Maximiliano José Nigro
@maxnigro.bsky.social
Associate Professor NTNU #NigroLab; Diversity of neurons; cortical circuits; Biologist looking at neurons with birdwatcher's eyes
https://nigrolab.com
https://nigrolab.com
Pinned
I am very proud to share the published version of our work on the Biogeography of fast-spiking interneurons in the mouse cortex
onlinelibrary.wiley.com/doi/full/10....
onlinelibrary.wiley.com/doi/full/10....
#Onthisday was published On the origin of the species by Charles Darwin
I get inspired by this book every time I read it
#evolution
#neuroskyence
I get inspired by this book every time I read it
#evolution
#neuroskyence
November 24, 2025 at 9:45 PM
#Onthisday was published On the origin of the species by Charles Darwin
I get inspired by this book every time I read it
#evolution
#neuroskyence
I get inspired by this book every time I read it
#evolution
#neuroskyence
Reposted by Maximiliano José Nigro
#QuattrocoloLab preprint out 👇! We explored changes in the proteome of hippocampal and dentate gyrus growth cones at early postnatal stages. We see that at P1 growth cones from the two subregions are very similar, but start to diverge from P3, with HP growth cones maturing earlier then DG ones.
Proteomic profile of hippocampal growth cones through early postnatal development https://www.biorxiv.org/content/10.1101/2025.11.10.687591v1
November 11, 2025 at 1:59 PM
#QuattrocoloLab preprint out 👇! We explored changes in the proteome of hippocampal and dentate gyrus growth cones at early postnatal stages. We see that at P1 growth cones from the two subregions are very similar, but start to diverge from P3, with HP growth cones maturing earlier then DG ones.
This week I am sharing what I think to be the most significant publication in biology since 1859. This paper opened the door to molecular biology and molecular genetics.
#neuroskyence
#neuroskyence
November 11, 2025 at 1:21 PM
This week I am sharing what I think to be the most significant publication in biology since 1859. This paper opened the door to molecular biology and molecular genetics.
#neuroskyence
#neuroskyence
The family coat of arms made at school by my son features birdwatching. I did get something right so far
@gquattrocolo.bsky.social
@gquattrocolo.bsky.social
October 29, 2025 at 3:49 PM
The family coat of arms made at school by my son features birdwatching. I did get something right so far
@gquattrocolo.bsky.social
@gquattrocolo.bsky.social
Developmental neuroscientists please keep inviting @gquattrocolo.bsky.social to your conferences. She is a great speaker and her lab is doing very interesting research. Plus she has great taste for presents to her husband when she returns from those conferences
October 24, 2025 at 4:53 PM
Developmental neuroscientists please keep inviting @gquattrocolo.bsky.social to your conferences. She is a great speaker and her lab is doing very interesting research. Plus she has great taste for presents to her husband when she returns from those conferences
In today’s lecture on microcircuit organization we will go through the classics from Penfield to Eccles and get to cell type specific optogenetics to dissect circuits for top down modulation of vision
How neurons connect to compute with a reminder to their biophysical properties
#neuroskyence
How neurons connect to compute with a reminder to their biophysical properties
#neuroskyence
October 15, 2025 at 8:55 AM
In today’s lecture on microcircuit organization we will go through the classics from Penfield to Eccles and get to cell type specific optogenetics to dissect circuits for top down modulation of vision
How neurons connect to compute with a reminder to their biophysical properties
#neuroskyence
How neurons connect to compute with a reminder to their biophysical properties
#neuroskyence
From the series “Once upon a time…the discoverers” an episode about Buffon and the concept of deep time
#evolution
#evolution
October 8, 2025 at 4:18 PM
From the series “Once upon a time…the discoverers” an episode about Buffon and the concept of deep time
#evolution
#evolution
Immunology is such a beautiful field! It was just recognized with another Nobel prize.
Richard Lewontin included it (“mechanisms of self-recognition”) in the five properties defining living organisms.
#biology
#neuroskyence
www.nobelprize.org/all-nobel-pr...
Richard Lewontin included it (“mechanisms of self-recognition”) in the five properties defining living organisms.
#biology
#neuroskyence
www.nobelprize.org/all-nobel-pr...
All Nobel Prizes 2025
The Nobel Prizes are awarded to those that have conferred the greated benefit to humankind.
www.nobelprize.org
October 6, 2025 at 11:40 AM
Immunology is such a beautiful field! It was just recognized with another Nobel prize.
Richard Lewontin included it (“mechanisms of self-recognition”) in the five properties defining living organisms.
#biology
#neuroskyence
www.nobelprize.org/all-nobel-pr...
Richard Lewontin included it (“mechanisms of self-recognition”) in the five properties defining living organisms.
#biology
#neuroskyence
www.nobelprize.org/all-nobel-pr...
To honor the memory of Dr Jane Goodall I am sharing her 1963 article for National Geographic Magazine
#neuroskyence
#neuroskyence
October 3, 2025 at 9:14 AM
To honor the memory of Dr Jane Goodall I am sharing her 1963 article for National Geographic Magazine
#neuroskyence
#neuroskyence
A pioneer of science, conservation and education who left a long lasting legacy.
Dr Jane Goodall
#neuroskyence
Dr Jane Goodall
#neuroskyence
October 2, 2025 at 8:07 AM
A pioneer of science, conservation and education who left a long lasting legacy.
Dr Jane Goodall
#neuroskyence
Dr Jane Goodall
#neuroskyence
Short philosophical summary for the lecture on Touch
#neuroskyence
#neuroskyence
October 1, 2025 at 8:56 AM
Short philosophical summary for the lecture on Touch
#neuroskyence
#neuroskyence
This looks like a promising step forward that improves quality rather than quantity
Looking forward to dig in more!
Looking forward to dig in more!
Neuropixels Ultra!
By @steinmetzneuro.bsky.social, who led a big collaboration
www.sciencedirect.com/science/arti...
By @steinmetzneuro.bsky.social, who led a big collaboration
www.sciencedirect.com/science/arti...
Ultra-high-density Neuropixels probes improve detection and identification in neuronal recordings
To understand the neural basis of behavior, it is essential to sensitively and accurately measure neural activity at single-neuron and single-spike re…
www.sciencedirect.com
September 30, 2025 at 7:00 PM
This looks like a promising step forward that improves quality rather than quantity
Looking forward to dig in more!
Looking forward to dig in more!
Grilling on a gorgeous fall evening while enjoying a wonderful Zinfandel. A present from the last master student graduated from the lab. The joys of teaching…
September 27, 2025 at 4:41 PM
Grilling on a gorgeous fall evening while enjoying a wonderful Zinfandel. A present from the last master student graduated from the lab. The joys of teaching…
This is very interesting. I am always terrified by extracellular recordings and Neuropixels have aggravated my anxiety. So I really appreciate studies like this.
#neuroskyence
#neuroskyence
Science of the day: Some spikes are just more positive than others, at least waveform-wise.
Side science: interested in these positive units (Punits), check out this work by Shirly Someck www.nature.com/articles/s42...
#Neuroscience #neuroskyence #punits #PositiveVibes
Side science: interested in these positive units (Punits), check out this work by Shirly Someck www.nature.com/articles/s42...
#Neuroscience #neuroskyence #punits #PositiveVibes
September 24, 2025 at 8:44 PM
This is very interesting. I am always terrified by extracellular recordings and Neuropixels have aggravated my anxiety. So I really appreciate studies like this.
#neuroskyence
#neuroskyence
Basket cells, parvalbumin expressing or fast-spiking neurons, names that emphasize different properties of the same type. However they are not all the same, like these in the mouse barrel cortex: one has axon in its layer; the other sends axon to other layers
Both are very beautiful
#neuroskyence
Both are very beautiful
#neuroskyence
September 24, 2025 at 1:04 PM
Basket cells, parvalbumin expressing or fast-spiking neurons, names that emphasize different properties of the same type. However they are not all the same, like these in the mouse barrel cortex: one has axon in its layer; the other sends axon to other layers
Both are very beautiful
#neuroskyence
Both are very beautiful
#neuroskyence
Congratulations to @seanfw.bsky.social and team! Very interesting project leveraging large scale models to make sense of the even larger scale anatomical diversity across regions and species
Very grateful to be among an inspiring group of @ukri.org Future Leaders Fellows for the next 4-7 years. We will infuse brain anatomy into AI to study shared principles and important differences in cognition across species. www.ukri.org/news/ukri-an...
UKRI announces winners of £120 million Future Leaders Fellowships
Research into the causes of lung cancer and Alzheimer’s disease are among 77 projects to be funded by UKRI’s Future Leaders Fellowships.
www.ukri.org
September 17, 2025 at 1:01 PM
Congratulations to @seanfw.bsky.social and team! Very interesting project leveraging large scale models to make sense of the even larger scale anatomical diversity across regions and species
Interesting passage. Buffon starts with a jab at the idea of classification by means of reducing beings to an ideal form. Are we, cell typers, exaggerating in splitting the transcriptomic dendrograms?
This reminds me of Agmon’s review
pubmed.ncbi.nlm.nih.gov/39091993/
#neuroskyence
#evolution
This reminds me of Agmon’s review
pubmed.ncbi.nlm.nih.gov/39091993/
#neuroskyence
#evolution
September 14, 2025 at 10:23 AM
Interesting passage. Buffon starts with a jab at the idea of classification by means of reducing beings to an ideal form. Are we, cell typers, exaggerating in splitting the transcriptomic dendrograms?
This reminds me of Agmon’s review
pubmed.ncbi.nlm.nih.gov/39091993/
#neuroskyence
#evolution
This reminds me of Agmon’s review
pubmed.ncbi.nlm.nih.gov/39091993/
#neuroskyence
#evolution
Our first steps into sensory processing is now online!
Work spearheaded by Rejwan Salih from experiments by @prime5222.bsky.social and François Pauzin
We were lucky to receive guidance from Davide Zoccolan on the analytical methods.
#neuroskyence
Work spearheaded by Rejwan Salih from experiments by @prime5222.bsky.social and François Pauzin
We were lucky to receive guidance from Davide Zoccolan on the analytical methods.
#neuroskyence
Tactile responses in the mouse perirhinal cortex show invariance to physical features of the stimulus https://www.biorxiv.org/content/10.1101/2025.08.15.670508v1
August 21, 2025 at 5:01 PM
Our first steps into sensory processing is now online!
Work spearheaded by Rejwan Salih from experiments by @prime5222.bsky.social and François Pauzin
We were lucky to receive guidance from Davide Zoccolan on the analytical methods.
#neuroskyence
Work spearheaded by Rejwan Salih from experiments by @prime5222.bsky.social and François Pauzin
We were lucky to receive guidance from Davide Zoccolan on the analytical methods.
#neuroskyence
This week I am sharing the closing remarks from Wallace’s The Malay Archipelago. Here Wallace gives a critique of of Victorian society and what he learned living with the people he met in his travels
#historyofscience
#biogeography
#neuroskyence
#historyofscience
#biogeography
#neuroskyence
August 18, 2025 at 9:47 AM
This week I am sharing the closing remarks from Wallace’s The Malay Archipelago. Here Wallace gives a critique of of Victorian society and what he learned living with the people he met in his travels
#historyofscience
#biogeography
#neuroskyence
#historyofscience
#biogeography
#neuroskyence
A few highlights of a morning birdwatching in Bali Barat National Park @gquattrocolo.bsky.social
The two mynas are critically endangered and the park has a repopulation program
The two mynas are critically endangered and the park has a repopulation program
August 2, 2025 at 5:51 PM
A few highlights of a morning birdwatching in Bali Barat National Park @gquattrocolo.bsky.social
The two mynas are critically endangered and the park has a repopulation program
The two mynas are critically endangered and the park has a repopulation program
This week I am sharing this very interesting study where I learned about the weird meiosis of 🌹
#evolution
#evolution
July 31, 2025 at 7:10 AM
This week I am sharing this very interesting study where I learned about the weird meiosis of 🌹
#evolution
#evolution
Reposted by Maximiliano José Nigro
📢 Calling all senior neuro postdocs: SYNAPSES brings postdocs from around the world to Yale to share their work during an in-person symposium on October 23, 2025. Apply today to present your research, talk with faculty members in 1:1s, & interact with Yale postdocs! 🧠🧪 Deadline Sept 7. #neuroskyence
July 30, 2025 at 1:31 PM
📢 Calling all senior neuro postdocs: SYNAPSES brings postdocs from around the world to Yale to share their work during an in-person symposium on October 23, 2025. Apply today to present your research, talk with faculty members in 1:1s, & interact with Yale postdocs! 🧠🧪 Deadline Sept 7. #neuroskyence
Bali surprised me as it did with Wallace
@gquattrocolo.bsky.social
@gquattrocolo.bsky.social
July 24, 2025 at 3:33 AM
Bali surprised me as it did with Wallace
@gquattrocolo.bsky.social
@gquattrocolo.bsky.social
July 12, 2025 at 9:58 AM
The sun is finally shining on the last day of recordings before going on vacation, so I make my own sunshine with an LED and some channelrhodopsin
#neuroskyence
#neuroskyence
July 9, 2025 at 1:12 PM
The sun is finally shining on the last day of recordings before going on vacation, so I make my own sunshine with an LED and some channelrhodopsin
#neuroskyence
#neuroskyence