Max Stammnitz
@maxstammnitz.bsky.social
Postdoc at @crg.eu Barcelona,
previously PhD at Cambridge University
Genomics | Mutational Scanning | Molecular Evolution 🧬🌱
www.pyrisentinel.eu ⛰️🌊 www.puntseq.com
previously PhD at Cambridge University
Genomics | Mutational Scanning | Molecular Evolution 🧬🌱
www.pyrisentinel.eu ⛰️🌊 www.puntseq.com
Pinned
The genetic architecture of an allosteric hormone receptor
Many proteins function as switches, detecting chemicals and transducing their concentrations into cellular responses. Receptor switches are key to the integration of environmental signals, yet it is n...
www.biorxiv.org
1 plant hormone receptor ☘️
3,500 mutants, to single-site saturation 🧬
>45,000 binding and abundance measurements 📶
Very happy to present our latest work – where deep mutational scanning meets the world of small molecules.
www.biorxiv.org/content/10.1...
With @benlehner.bsky.social
[1/7]
3,500 mutants, to single-site saturation 🧬
>45,000 binding and abundance measurements 📶
Very happy to present our latest work – where deep mutational scanning meets the world of small molecules.
www.biorxiv.org/content/10.1...
With @benlehner.bsky.social
[1/7]
Reposted by Max Stammnitz
TF-MAPS: fast high-resolution functional and allosteric mapping of DNA-binding proteins by @XianghuaLi2
Are Transcription Factors really 'undruggable'?
www.biorxiv.org/content/10.1...
Are Transcription Factors really 'undruggable'?
www.biorxiv.org/content/10.1...
TF-MAPS: fast high-resolution functional and allosteric mapping of DNA-binding proteins
Transcription factors (TFs) bind specific DNA sequences to control gene expression. Modulating TF activity is of considerable therapeutic interest but very few TFs have been successfully drugged. TF D...
www.biorxiv.org
October 23, 2025 at 12:50 PM
TF-MAPS: fast high-resolution functional and allosteric mapping of DNA-binding proteins by @XianghuaLi2
Are Transcription Factors really 'undruggable'?
www.biorxiv.org/content/10.1...
Are Transcription Factors really 'undruggable'?
www.biorxiv.org/content/10.1...
Reposted by Max Stammnitz
Why fundamental research is fundamental to progress, seeding major breakthroughs
Editorial @nature.com this week
And 7 basic science discoveries that changed the world
nature.com/articles/d41...
nature.com/articles/d41...
Editorial @nature.com this week
And 7 basic science discoveries that changed the world
nature.com/articles/d41...
nature.com/articles/d41...
October 29, 2025 at 12:58 PM
Why fundamental research is fundamental to progress, seeding major breakthroughs
Editorial @nature.com this week
And 7 basic science discoveries that changed the world
nature.com/articles/d41...
nature.com/articles/d41...
Editorial @nature.com this week
And 7 basic science discoveries that changed the world
nature.com/articles/d41...
nature.com/articles/d41...
Reposted by Max Stammnitz
Are you looking for a PhD? Join us in Barcelona! You'll dive into a community of >100 PhD students from 30 countries exploring the frontiers of biology. You can also join an online workshop on 6 November (15:00 CET) to learn how to find the right lab for you.
More info: www.crg.eu/en/content/t...
More info: www.crg.eu/en/content/t...
October 23, 2025 at 7:56 AM
Are you looking for a PhD? Join us in Barcelona! You'll dive into a community of >100 PhD students from 30 countries exploring the frontiers of biology. You can also join an online workshop on 6 November (15:00 CET) to learn how to find the right lab for you.
More info: www.crg.eu/en/content/t...
More info: www.crg.eu/en/content/t...
Reposted by Max Stammnitz
Opportunity for a Master’s/Bachelor’s student:
- Join us for up to 5 months 🗓️
- Build computational/mathematical models 💻
- Learn about genotype-phenotype maps and evolution 🧬
- Work closely with PhD student Manuela Giraud - full info here:
www.crg.eu/en/content/t...
- Join us for up to 5 months 🗓️
- Build computational/mathematical models 💻
- Learn about genotype-phenotype maps and evolution 🧬
- Work closely with PhD student Manuela Giraud - full info here:
www.crg.eu/en/content/t...
October 7, 2025 at 2:38 PM
Opportunity for a Master’s/Bachelor’s student:
- Join us for up to 5 months 🗓️
- Build computational/mathematical models 💻
- Learn about genotype-phenotype maps and evolution 🧬
- Work closely with PhD student Manuela Giraud - full info here:
www.crg.eu/en/content/t...
- Join us for up to 5 months 🗓️
- Build computational/mathematical models 💻
- Learn about genotype-phenotype maps and evolution 🧬
- Work closely with PhD student Manuela Giraud - full info here:
www.crg.eu/en/content/t...
Reposted by Max Stammnitz
🚨JOB ALERT🚨
FRIENDS PLEASE SPREAD and RT
We are building a small expert team within the @bokelab.bsky.social at @crg.eu @prbb.org to investigate fundamental questions in oocyte cell biology, focusing on how proteostasis regulation influences dormancy and fertility.
See below 2 calls👇
FRIENDS PLEASE SPREAD and RT
We are building a small expert team within the @bokelab.bsky.social at @crg.eu @prbb.org to investigate fundamental questions in oocyte cell biology, focusing on how proteostasis regulation influences dormancy and fertility.
See below 2 calls👇
October 2, 2025 at 11:00 AM
🚨JOB ALERT🚨
FRIENDS PLEASE SPREAD and RT
We are building a small expert team within the @bokelab.bsky.social at @crg.eu @prbb.org to investigate fundamental questions in oocyte cell biology, focusing on how proteostasis regulation influences dormancy and fertility.
See below 2 calls👇
FRIENDS PLEASE SPREAD and RT
We are building a small expert team within the @bokelab.bsky.social at @crg.eu @prbb.org to investigate fundamental questions in oocyte cell biology, focusing on how proteostasis regulation influences dormancy and fertility.
See below 2 calls👇
Reposted by Max Stammnitz
O maior fotógrafo do Brasil e um dos maiores do mundo descansa hoje. Vá em paz, Sebastião Salgado.
May 23, 2025 at 3:24 PM
O maior fotógrafo do Brasil e um dos maiores do mundo descansa hoje. Vá em paz, Sebastião Salgado.
Reposted by Max Stammnitz
🎲 Our paper on the genetics, energetics, and allostery in proteins with randomized cores and surfaces is out today @science.org!
🧬 By charting a protein’s sequence universe, we could rationalize which versions were kept through evolution – and why many stable ones were not.
🧬 By charting a protein’s sequence universe, we could rationalize which versions were kept through evolution – and why many stable ones were not.
July 25, 2025 at 6:27 AM
🎲 Our paper on the genetics, energetics, and allostery in proteins with randomized cores and surfaces is out today @science.org!
🧬 By charting a protein’s sequence universe, we could rationalize which versions were kept through evolution – and why many stable ones were not.
🧬 By charting a protein’s sequence universe, we could rationalize which versions were kept through evolution – and why many stable ones were not.
1 plant hormone receptor ☘️
3,500 mutants, to single-site saturation 🧬
>45,000 binding and abundance measurements 📶
Very happy to present our latest work – where deep mutational scanning meets the world of small molecules.
www.biorxiv.org/content/10.1...
With @benlehner.bsky.social
[1/7]
3,500 mutants, to single-site saturation 🧬
>45,000 binding and abundance measurements 📶
Very happy to present our latest work – where deep mutational scanning meets the world of small molecules.
www.biorxiv.org/content/10.1...
With @benlehner.bsky.social
[1/7]
The genetic architecture of an allosteric hormone receptor
Many proteins function as switches, detecting chemicals and transducing their concentrations into cellular responses. Receptor switches are key to the integration of environmental signals, yet it is n...
www.biorxiv.org
June 2, 2025 at 1:36 PM
1 plant hormone receptor ☘️
3,500 mutants, to single-site saturation 🧬
>45,000 binding and abundance measurements 📶
Very happy to present our latest work – where deep mutational scanning meets the world of small molecules.
www.biorxiv.org/content/10.1...
With @benlehner.bsky.social
[1/7]
3,500 mutants, to single-site saturation 🧬
>45,000 binding and abundance measurements 📶
Very happy to present our latest work – where deep mutational scanning meets the world of small molecules.
www.biorxiv.org/content/10.1...
With @benlehner.bsky.social
[1/7]