MetaMorpheus
@metamorpheus.bsky.social
600 followers 270 following 130 posts
The number of people using expensive, black-box software for proteomics is bewildering.
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metamorpheus.bsky.social
I've seen a spike in major ampullate spidroins (MaSp1 and MaSp2) from a "certain lab in pittsburgh".
Reposted by MetaMorpheus
lukaskall.bsky.social
There is a position open in our lab, within this network. Our project deals with assessing identification and quantification errors for MS-based proteomics. www.protaiomics.eu/project/dc13...
Please check out all the project descriptions at the site below:
metamorpheus.bsky.social
Not bike mechanic? Aren’t you all about the tour de French fries.
metamorpheus.bsky.social
No one has stepped up to be our cult leader. I’d follow you anywhere. Interested?
metamorpheus.bsky.social
So. I want to hear about everyone’s alternate life dream. When you finally get disenfranchised, what would you do if you could do what you want?
metamorpheus.bsky.social
I’m thinking we should all form a colony of off-grid proteomics ex-pats (read: formerly employed) where we can all live out our dreams. We can call it Animal Farm.
metamorpheus.bsky.social
Well. You know my dream....
metamorpheus.bsky.social
you also probably remember ripping of the strips on the sides of the paper that were used to feed it. The times they are a changin.
a blurred image of a person sitting at a desk in front of a monitor
ALT: a blurred image of a person sitting at a desk in front of a monitor
media.tenor.com
metamorpheus.bsky.social
What a missed opportunity!!!!!!! @proteomicsnews.bsky.social

Backyard Proteomics: A Case Study with the Black Widow Spider | Journal of Proteome Research pubs.acs.org/doi/full/10....
pubs.acs.org
metamorpheus.bsky.social
I don't know anything about the monetary side of this.
1. I do love to see more of my old #TeamMassSpec friends here
2. But, the #TeamMassSpec conversation is a pale shadow of its former self :(
metamorpheus.bsky.social
Referee questioned the adoption/accessibility of lc-ms to the research community. I think that's reasonable. So, realistically, how big of a problem do I need to solve to make my method worth the investment and effort? What is a thoughtful response to this critique?
metamorpheus.bsky.social
Maybe you could work there and develop a new biometric test that will make it even harder and take longer to get through security? Honestly, it's getting to the point that it is not worth the effort for me to buy a 100 pounds of canned tuna to save 12cent.
metamorpheus.bsky.social
IDK. I'm confidant that I am wrong most of the time and I don't attend CS conferences. This may be a widespread problem.
Reposted by MetaMorpheus
pastelbio.bsky.social
Improved Detection of Differentially Abundant Proteins through FDR-Control of Peptide-Identity-Propagation pubs.acs.org/doi/10....

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#proteomics #prot-paper
metamorpheus.bsky.social
out of curiosity, and only if you are willing, what are your preferred modes of communication?
metamorpheus.bsky.social
on the off chance that you are wondering..... ChatGPT put this little questionnaire together for you to peform an at-home assessment. Enjoy.
metamorpheus.bsky.social
Phenotype of the contemporary grant referee:
metamorpheus.bsky.social
referees found a similar hole in my last grant application. must be spreading.
metamorpheus.bsky.social
Hey Team Proteomics.

New release of MetaMorpheus now natively supports Bruker .d files for DDA PASEF.

Also now supporting .msalign as inputs.

get your copy free now while they last:
github.com/smith-chem-w...
Releases · smith-chem-wisc/MetaMorpheus
Proteomics search software with integrated calibration, PTM discovery, bottom-up, top-down and LFQ capabilities - smith-chem-wisc/MetaMorpheus
github.com
metamorpheus.bsky.social
Good luck. You've done everything within your control. recommend managing your expectations. don't ask me how i know.