Lightnews — Scholar-powered news

Michelle Jansman @michellejansman.bsky.social · 4d

I had a great time attending and presenting my work at #BMES2025 in San Diego. It was such a nice opportunity to talk about my and others' projects on bone tissue engineering. Thank you everyone for the great talks! 🧪👩‍🔬

Presenting my project on Modulating oxygen tension in bone tissue engineering via hemoglobin-loaded microribbon hydrogels.

2 17

Reposted by Michelle Jansman

Tanja Schneider @taschn.bsky.social · 6d

🍁 Beautiful autumn atmosphere at #DTU this morning

#Autumn
#Photography
#Nature
#Morninglight

Red vine leaves turned red on a wall/building in autumn

1 10

Michelle Jansman @michellejansman.bsky.social · 10d

Excited to be attending #BMES2025!

I will be presenting my work on fabricating oxygen releasing scaffolds for bone tissue engineering in Friday's poster session (T37). Interested in targeting hypoxia, hemoglobin-based oxygen carriers, or bone TE? Please come say hi 😀

🧪👩‍🔬

Poster T37. Modulating oxygen tension in bone tissue engineering via hemoglobin-loaded microribbon hydrogels.

1 7

Reposted by Michelle Jansman

Elisabeth Bik - Perpetrator 5, a fraudulent microbiologist @elisabethbik.bsky.social · 13d

The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”

Cartoon from the Nobel Assembly showing the three prize winners, their names, and “for their discoveries concerning peripheral immune tolerance.”

20 99

Reposted by Michelle Jansman

AJ Lauer @ayjaylauer.bsky.social · 26d

What’s your #1 survival tip for scientific conference season? 👀

Mine: update LinkedIn, sponsor others, and do something fun off-site

Read more about why these 3 strategies work on the Thriving Ibis blog: www.thrivingibis.com/post/3-must-...

#AcademicSky #WomenInSTEM #WomenInTech #WomenInScience

3 Conference Preparation Tips for Science and Tech Events

In addition to making last-minute updates to your talk 👀 Update your LinkedIn profile before you go!Make it easy for new connections to find and follow your work.Make sure everything is current. Doubl...

www.thrivingibis.com

3 9

Michelle Jansman @michellejansman.bsky.social · Sep 12

Excited to be a topic editor for:
Synthetic Biology in Pharmacology: Engineering Circuits and Cells for Therapeutics

We are seeking articles regarding:
- Artificial Cells for Drug Delivery
- Metabolic Engineering for Drug Production
- Synthetic Gene Circuits
tinyurl.com/38j4d6u4

🧪👩‍🔬#Chemsky

Frontiers | Synthetic Biology in Pharmacology: Engineering Circuits and Cells for Therapeutics

Synthetic biology, an interdisciplinary field blending principles from molecular biology, organic chemistry, computational modeling, and nanobiotechnology, f...

www.frontiersin.org

1 6 11

Reposted by Michelle Jansman

Riccardo Levato @riclevato.bsky.social · Sep 10

Thanks nu.nl for featuring our recent research results on GRACE #bioprinting @natureportfolio.nature.com . Check out the "good news" section (a fitting home and anme!) of Nu . nl of today:

🇳🇱 www.nu.nl/goed-nieuws/...

@utrechtuniversity.bsky.social
#3dprinting

Nieuwe stap in 3D-printen: ook menselijk weefsel kan worden 'geprint'

Onderzoekers van de Universiteit Utrecht zijn een stap dichter bij het 3D-bioprinten van organen. De nieuwe techniek genaamd GRACE kan door middel van kunstmatige intelligentie zelf meedenken en sugge...

www.nu.nl

1 9

Reposted by Michelle Jansman

The Wyss Institute at Harvard University @wyssinstitute.bsky.social · Aug 13

Scientists at the Wyss have created cellular "backpacks," disk-shaped nanoparticles that can stick to immune cells without being engulfed, and release a steady stream of cytokines into their "host" cells to keep them activated.

Cellular “Backpacks” to Fight Cancer, Autoimmune Disorders, and More

Macrophages are very malleable immune cells, but that also means that they can be influenced by cancerous tumors and inflammatory processes. Our cellular "backpacks" stick to macrophages and can deliv...

wyss.harvard.edu

4 9

Reposted by Michelle Jansman

Nikolay Tumanov @ntumanovxray.bsky.social · Jul 28

Some say that #MOF were discovered in 1900s, but this figure from 1760s clearly show a crystal structure of a MOF with inclusion in pores. Look - metal centers, linkers, guest molecules, all in!

#MOF #chemsky #BraggYourPattern reporting from Portugal

1 6 32

Reposted by Michelle Jansman

Chemistry World @chemistryworld.com · Jun 26

New research shows that simply changing how a reaction vessel is positioned on a magnetic stirrer can significantly change a reaction's speed and product quality, influencing the reproducibility of results. #ChemSky #ScienceSky #EduSky

Position of flask on magnetic stirrers can drastically affect reproducibility of experiments

Comprehensive examination reveals improper siting of reaction vessels can affect catalyst formation, alter nanoparticle formation and change yields

www.chemistryworld.com

3 12 26

Reposted by Michelle Jansman

Climate, Ecology, War & More by Dr. Glen Barry, BigEarthData.ai @bigearthdata.bsky.social · Jun 7

Instant assembly of collagen for tissue engineering and bioprinting
->Nature | More info from EcoSearch

Instant assembly of collagen for tissue engineering and bioprinting

(a) Video recording showing high-throughput micro-liter collagen disk fabrication. Red boxes mark the same location where a 5 μL collagen droplet was deposited at t = 0. Scale bar, 2 mm. (b) Reflectance confocal microscopy reveals pore sizes from the...

www.nature.com

1 2

Reposted by Michelle Jansman

Ritu Raman @rituraman.bsky.social · Jun 6

Great to work on this review with Miguel Castilho, @ruidomingues.bsky.social and colleagues - we outline methods to design responsive #biomaterials that enable fabrication of more complex multicellular systems:

www.cell.com/trends/biote...

#TissueEngineering

Meta-adaptive biomaterials: multiscale, spatiotemporal organization and actuation in engineered tissues

Organized cell architecture and dynamic forces are key for (re)creating native-like tissue function (e.g., contractile soft tissues). However, few studies have explored the combined effects of materia...

www.cell.com

7 8

Reposted by Michelle Jansman

Anna Clemens, PhD @annaclemens.com · Jun 3

Not sure where to publish your research? Here are 7 bookmark-worthy tools that help you decide on the right target journal or repository for your research!

A thread. 🧵

#ScienceSky
#PhDSky
#Postdoc

3 1 3

Reposted by Michelle Jansman

Tissue Engineering, Parts A, B, & C @tissueengineering.bsky.social · Jun 3

Check out this recent article from @bioe-stanford.bsky.social‬ on donor variability and 3D culture models influence human mesenchymal stem cell differentiation!

Read more here: doi.org/10.1089/ten....

1 2

Michelle Jansman @michellejansman.bsky.social · Apr 30

Three new cases reported on using artificial oxygen carriers, by Dr Zhen Mei (UCLA, US).
HBOC-201 was successfully used on sickle cell disease patients as bridge therapy and/or as substitute for allogeneic blood transfusion.
doi.org/10.1097/MJT....

🧪 #MedSky #HBOCs

Artificial Oxygen Carriers Save Lives in Expanded Access... : American Journal of Therapeutics

en conventional blood products are not available for transfusion yet the patient requires additional oxygen-carrying support, artificial oxygen carriers may be required. However, there are no such FDA...

doi.org

1 5

Reposted by Michelle Jansman

Ryan M. Pearson, PhD. @ryanmpearson.bsky.social · Jan 22

Extremely excited to share our latest research in Nature Communications @naturecomms.bsky.social! We show that inflammatory disease progression shapes nanoparticle biomolecular corona-mediated immune activation profiles. Congratulations to all authors!! rdcu.be/d68EH @umbaltimore.bsky.social

Inflammatory disease progression shapes nanoparticle biomolecular corona-mediated immune activation profiles

Nature Communications - Nanoparticle biomolecular corona fingerprints vary with disease state. Here, the authors use integrated multi-omics to show that inflammatory disease dynamics alter corona...

rdcu.be

3 8

Michelle Jansman @michellejansman.bsky.social · Apr 18

Attended an interesting talk by Prof. Derek Amanatullah (Stanford Med), discussing dormant infections in joint replacements. Concl.: MPS-mediated response as biomarker enables better screening and patient prognosis.

doi.org/10.1186/s129...

#AcademicSky #MedSky 🧪
@stanfordmedicine.bsky.social

The mononuclear phagocyte system obscures the accurate diagnosis of infected joint replacements, by Manasherob et al. Published in the Journal of Tranlational medicine, 2024.
https://doi.org/10.1186/s12967-024-05866-5.
Below: Schematic understanding of dormant infection (green) as an MPS-mediated IL17 response to biofilm inhibiting PMN recruitment and function when compared to patients with (red) or without (blue) and active infection.

2 5

Michelle Jansman @michellejansman.bsky.social · Mar 18

Fully agree with this piece 🧪
In the past, I've contacted a Prof that miscited my paper (we did do the research, just in another ref). No response..

I think the reason is the long process of corrections post publ. So, better to ignore. Wrong citations should be treated easier, it will help everyone

Part of the article:
Peer review cannot realistically verify every reference. There simply is not enough time. Today, targeted AI tools could potentially help detect mis-citations or odd citation patterns, making the work more robust [4].

Journals should also offer a clear, low-friction process for post-publication corrections. A publication should not be set in stone after proofs. A formal reporting mechanism must allow authors to challenge and fix citation errors without needing the citing author’s approval.

1 4

Michelle Jansman @michellejansman.bsky.social · Mar 10

It shows that each approach has its adv/disadvantages, whether using stem cells or particle systems.
While I am more interested in the latter, it is good to follow all the progresses made in each approach. Knowing a clinical trial was done in 2022 shows great promise for artificial blood!

Michelle Jansman @michellejansman.bsky.social · Mar 10

Interesting & short article about artificial blood in Aljazeera, focusing on lab-grown blood (the alternative to HBOCs /PFCs).
Also summarizes their main disadvantage: "producing lab-grown blood is currently much more expensive than using donated blood".

1/2
🧪 #chemsky

David Davies @acute-tomato.bsky.social · Mar 9

How close are scientists to producing artificial blood? ~

How close are scientists to producing artificial blood?

Clinical trials from the UK to Japan are exploring man-made substitutes for blood.

buff.ly

1 2 4

Michelle Jansman @michellejansman.bsky.social · Mar 10

Another TissueTalk is online, this time with with Prof. Warren Grayson (John Hopkins U, US)🧪
www.youtube.com/watch?v=yNuK...

Gave a clear introduction to the use of scRNA-seq in deciphering cells’ expressions during bone regeneration. Looking forward to reading the article on this.

#biomaterials

Summary slide from the TissueTalk given by Prof. Warren Grayson. Shows that 1) Multimodal imaging and QLS provide rich dataset that illuminate the interplay between vasculature and bone. 2) Adapted QLSM imaging and analysis pipeline used to elucidate aging neural dynamics. 3) Single cell sequencing revealed proliferative factors that may be signaling to osteoprogenitors to maintain stemness in critical-sized defects.

1

Michelle Jansman @michellejansman.bsky.social · Mar 4

New review paper on artificial O2 carriers by Mohanto et al (Shosun U, KR)🧪
-Products: Hb-, PFC-, stem cell-, bubble-based O2 carriers
-Targets incl: anemia, tumor hypoxia, hemor. shock, tissue regeneration, organ preservation
-Finishes with key considerations for future

doi.org/10.1186/s129...

Paper: Therapeutic delivery of oxygen using artificial oxygen carriers demonstrates the possibility of treating a wide range of diseases, by Mohanto et al. Published in Journal of Nanobiotechnology, 2025. https://doi.org/10.1186/s12951-024-03060-9

TOC shows the four discussed products: hemoglobin-, perfluorocarbon-, stem cell-, and micro/nanobubble-based oxygen carriers. For each product, various disease models are targeted. These include i.a. hemorrhagic shock, oxygen preservation, tumor hypoxia, respiratory failure, stroke, chronic hypoxia, and sickle cell crisis. Fig 9 shows the required goals for the perfect O2 carrier. Include i.a. efficient O2 release, extended half-life, innate to inflammatory system, and no acute or long-term toxicities.

6

Michelle Jansman @michellejansman.bsky.social · Feb 28

Another way to showcase the group's research👩‍🎨🧪

www.fanyanggroup.com/paintourrese...
Visit the site to see all 14 paintings (and maybe more to come!)
#AcademicSky

Paint Our Research page on the Fan Yang Lab website. Showing the first three painings called: Tree of Life, Conversations, and the Crabs Cycle

2 29