Iñaki Ruiz-Trillo
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multicellgenome.bsky.social
Iñaki Ruiz-Trillo
@multicellgenome.bsky.social
Leading a research lab with Elena Casacuberta. We aim to unravel how #protists evolved into multicellular animals.
#Multicellularity #Ichthyosporea #holozoans #filastereans #development #diversity #genomes #modelsystems
https://multicellgenome.com
Pinned
The quest for the #Magnificent8 continues! This time, in search of Freship1 and Freship2 in Lago de Sanabria. See Marina, Alicia, and Rubén in action!
Thanks to Antonio from proyectoagua; Juan and David from Europarques & many others!
#ProtistsOnSky @ibe-barcelona.bsky.social @prbb.org
What do unicellular organisms teach us about cancer? 🦠 Elena took the stage at @congresofuturo.bsky.social (LatAm's biggest science event!) to explain the connection.🎥 Watch Elena's talk:
www.youtube.com/live/eyEYS3a...
@ibe-barcelona.bsky.social @csic.es @prbb.org @icreacommunity.bsky.social
CONGRESO FUTURO 2026 | SÁBADO 17 DE ENERO (IDIOMA ORIGINAL)
YouTube video by Congreso Futuro
www.youtube.com
January 19, 2026 at 8:36 AM
🎓Gonzalo defended his PhD on #Capsaspora aggregation & animal origins. Privilege to co-supervise with Koryu—watching a former trainee mentor the next generation is so cool! Thanks Núria, Nick & Cristina for the stimulating discussion! @icreacommunity.bsky.social @ibe-barcelona.bsky.social
January 17, 2026 at 10:07 PM
Elena presenting our work on animal origins at Universidad Católica del Norte, Antofagasta, as part of the #CongresoFuturo #multicellularity #ichthyosporeans @prbb.org @csic.es @csicdivulga.bsky.social @csiccat.bsky.social @ibe-barcelona.bsky.social
January 16, 2026 at 9:51 PM
📱Is the origin of animals comparable to the origin of the smartphones? Yes! See our new review in @embojournal.org where we show how important it was the new "Operating System" (animalOS)for animals to evolve! with @ricardsole.bsky.social, Nick and Elena @ibe-barcelona.bsky.social @csic.es @prbb.org
January 15, 2026 at 11:00 AM
Reposted by Iñaki Ruiz-Trillo
Our latest: Independent origins of spicules reconcile paleontological and molecular evidence of sponge evolutionary history, led by @meleonora-rossi.bsky.social with help from friends @bristolpalaeo.bsky.social including @anariesgo.bsky.social @evopalaeo.bsky.social Davide Pisani and many others
Independent origins of spicules reconcile paleontological and molecular evidence of sponge evolutionary history
Sponges have a cryptic Ediacaran history because ancestral sponges were soft-bodied and had low fossilization potential.
www.science.org
January 8, 2026 at 7:39 AM
Reposted by Iñaki Ruiz-Trillo
How did organs originated in the evolution of multicellularity? Despite their obvious importance, we still lack a theory of evolutionary organogenesis. Here's a @cp-trendsecolevo.bsky.social paper on how the placenta can offer answers @multicellgenome.bsky.social www.researchgate.net/profile/Oliv...
December 26, 2025 at 11:28 AM
The real drama of life happened "backstage" in the unicellular world. 🎭🧬 #protistsonSky
Our postdoc Vika Shabardina is co-organizing this symposium with Annia (@ankarn.bsky.social). Two brilliant minds leading the evocell way!
Plus, a talk by @vikramalva.bsky.social. 👇
January 1, 2026 at 10:45 AM
Reposted by Iñaki Ruiz-Trillo
New preprint out! Using ~75k environmental OTUs + 77 fossil calibrations, we reconstructed a Proterozoic timeline of eukaryote evolution. Our results show crown eukaryotes were already diversifying >1.6 Ga, long before the first undisputed fossils (~1.05 Ga).
🔗 DOI: www.biorxiv.org/content/10.6...
December 15, 2025 at 8:19 AM
Reposted by Iñaki Ruiz-Trillo
Are you very busy but still want to learn what Aphelids are and why they are important to understand the evolution of Fungi?
Then check out our “Quick guide” on Aphelids published in collaboration with @deemteam.bsky.social, Sergey and Guifré. #protistsonsky
doi.org/10.1016/j.cu...
December 15, 2025 at 5:41 PM
Reposted by Iñaki Ruiz-Trillo
🎄 Just published 🎉! Our ongoing genome sequencing of the basal dinoflagellate Oxyrrhis marina uncovered a new lineage of endogenized Polinton-like viruses, OmPLV. Notably, OmPLV encodes ... [cont]
#VirEvol #MicroSky #Mevosky #SymbioSky #ProtistsOnSky
Endogenized polinton-like viruses in the dinoflagellate Oxyrrhis marina uncover novel PolB fusion
Marine viruses are ubiquitous entities that impact the biology of a large fraction of prokaryotic and eukaryotic diversity. Dinoflagellates are heterotrophic, mixotrophic and photosynthetic eukaryotes...
doi.org
December 23, 2025 at 4:39 PM
Very nice evidence of the power of convergence evolution in #terrestrialization. Congrats to all authors! @martaalvarez.bsky.social Jordi, Davide, @phil-donoghue.bsky.social & Jialin #metazoans
Happy to share Jialin's first publication. She did a great job exploring the transition to land in animals. Co-supervised by the great Jordi Paps and me and in collaboration with Davide Pisani and @phil-donoghue.bsky.social
nature.com Nature @nature.com · Nov 13
Nature research paper: Convergent genome evolution shaped the emergence of terrestrial animals

go.nature.com/4i0i61w
November 13, 2025 at 6:57 PM
Indeed! Very nice collaboration with @irenedelrey.bsky.social @sebasn1.bsky.social @konsmitsi.bsky.social @jtrinidad13.bsky.social Montse Elias, Padhu & others to decipher the origin of the #plasmalogen biosynthesis pathway. @ibe-barcelona.bsky.social @icreacommunity.bsky.social @csic.es
November 12, 2025 at 7:05 PM
Reposted by Iñaki Ruiz-Trillo
And for the online participants we had the first round of Backstage Interviews led by Vika interviewing Iñaki Ruiz-Trillo and Laura Nuño de la Rosa. #Multicellverse @multicellgenome.bsky.social
October 9, 2025 at 4:58 PM
Reposted by Iñaki Ruiz-Trillo
📣The #EMBOWorkshop hosted by @multicellgenome.bsky.social Lab has begun!

🔬Three days filled with talks from international experts exploring the #evolution and origins of #multicellularity🦠🧬

#Multicellverse #UnravellingEvolution #DiscoveringLife
October 9, 2025 at 8:49 AM
Thrilled to see choanoflagellates can glide! I think this provide further support to the stunning complexity of the unicellular ancestor of animals, as we have been proposing. Congrats @thibautbrunet.bsky.social ! very nice work. #AnimalOrigins #choanos #multicellularity #protistsOnSky
September 12, 2025 at 10:52 AM
Less than a month away! 📣 Our lab is so excited to co-host the #EMBOWorkshop on the evolution of #multicellularity.
Get ready to dive deep into the origins of multicellular life across all kingdoms. 🔬See you in Barcelona (or online) soon!

@prbb.org @csic.es
📣The #EMBOWorkshop is almost here!

🔬 Learn all about the evolution and origins of multicellularity 🦠🧬 from October 9–11, ONLINE🤩

🗓️ Register by September 5 ➡️ https://meetings.embo.org/event/25-multicellularity

#UnravellingEvolution #DiscoveringLife
September 10, 2025 at 9:46 AM
#PhDposition! Great PI, nice project, wonderful environment.
@IBE_Barcelona #microbes #evolution
We are hiring a PhD student! Are you fascinated by microbes and evolution? Come join us in Barcelona!
September 10, 2025 at 9:37 AM
What you're looking at is a brand new protist species! 🤯🔬
Isn't it beautiful?
This image is just a glimpse of what's to come. We can't wait to share our full findings soon, in partnership with Guifré @beaplab.bsky.social @luisjagago.bsky.social. Stay tuned! #NewSpecies #protistsonSky #diversity
September 9, 2025 at 4:21 PM
Reposted by Iñaki Ruiz-Trillo
Editor-in-Chief Joel Dacks looks back on the year and shares some of our new initiatives, including "Issue Highlight" image and AI use guidance.

Read about these initiatives and more in the Editor's Message
onlinelibrary.wiley.com/doi/10.1111/...

#protistsonsky
Summer 2025 Editor‐In‐Chief Message
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onlinelibrary.wiley.com
September 5, 2025 at 5:19 PM
More on the ancient foundation of animal development. Coyle & King illustrate how core regulatory modules were present in our pre-animal ancestors. The key was not invention, but recycling & new protein interactions. #CellBiology #multicellularity #protistsOnSky
www.nature.com/articles/s41...
September 8, 2025 at 9:33 AM
We couldn't imagine a better way to send off the incredible @MartonaAlvarez than with black paella and sea views! 🥘
Marta, thanks for everything! We will be cheering you on every step of the way. 🥰🥰🥰
#science #farewell #newbeginnings #teamwork #academialife
@ibe-barcelona.bsky.social @prbb.org
September 5, 2025 at 4:33 PM
Reposted by Iñaki Ruiz-Trillo
Cnidarian-Microbe Interactions
Fully-funded postdoctoral position is available in the Gibson Lab at the Stowers Institute to investigate any aspect of cnidarian-microbe interactions. Strong background in coral symbiosis or eukaryotic microbiology preferred.
Contact Matt Gibson: [email protected]
August 14, 2025 at 4:50 PM
Congrats Haillot & the whole @ulrichtechnau.bsky.social lab! Another brilliant example of how we shouldn't assume simplicity in non-bilaterian animals. Triploblasty’s roots seem to run older than we thought! Nice to see a crosstalk between MAPK, β-catenin & Notch to define identities. #EvoDevo
Finally, the excellent postdoc work of Emmanuel Haillot is out, where he dissected the integration of Wnt, MAPK and Notch signaling in defining mesoderm and endoderm identities in the diploblast Nematostella. Strikingly similar to sea urchins. www.nature.com/articles/s41...
September 2, 2025 at 12:36 PM
🚀 Watching Núria Ros-Rocher grow from PhD student to independent @cnrs.fr researcher has been a joy. Talent + grit + kindness = 🔥. Huge congrats, Núria—and kudos, Thibaut. And I know this is just the beginning! Can’t wait for the next C. flexa chapters!
A thousand bravos for Núria Ros-Rocher, who just secured a permanent @cnrs.fr researcher position in our lab. These positions are (too) rare but give much-needed job security to young scientists and allow long-term projects. Núria will dive deep into the natural history of C. flexa 🧪🌊 #ProudPI
September 2, 2025 at 8:26 AM