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Nihar Desai MD, DM

@nihardesai7.bsky.social

600 followers 120 following 86 posts

Bone marrow transplant physician at the Princess Margaret Cancer Center, Toronto • Love wildlife, classic rock, and common sense medicine • Follow to learn hematology ❤ @nihardesai89 on that Elon app 🤷🏼

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Reposted by Nihar Desai MD, DM

Arjun Law @haemophage.bsky.social · Mar 25

A bit of a #HumbleBrag
The Hans Messner AlloBMT program @hansbmt.bsky.social just infused the 200th allograft of this fiscal year. A new record for us and for Canada! #bmtsm
@tomam04.bsky.social @nihardesai7.bsky.social @uhnresearch.bsky.social

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Reposted by Nihar Desai MD, DM

OncoDaily @oncodaily.bsky.social · Mar 21

Central Nervous System Manifestations of Graft-Versus-Host Disease - Nihar Desai
@nihardesai7.bsky.social

oncodaily.com/science/2581...

#Cancer #CentralNervousSystem #Medicine #Health #CancerResearch #Oncology #OncoDaily

Nihar Desai: Central Nervous System Manifestations of Graft-Versus-Host Disease - OncoDaily

Nihar Desai: Central Nervous System Manifestations of Graft-Versus-Host Disease / cancer, central nervous system, CNS, European Journal of Hematology, fight

oncodaily.com

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Nihar Desai MD, DM @nihardesai7.bsky.social · Mar 16

Central venous catheter and thrombosis!

Nihar Desai MD, DM @nihardesai7.bsky.social · Mar 5

Reviewer 2 walking away after destroying the manuscript 😭😭

Reposted by Nihar Desai MD, DM

OncoDaily @oncodaily.bsky.social · Mar 4

25 years of imatinib - Nihar Desai
@nihardesai7.bsky.social

oncodaily.com/drugs/nihar-...

#Cancer #CancerResearch #CancerTreatment #Medicine #Health #Oncology #OncoDaily

Nihar Desai: 25 years of imatinib - OncoDaily

Nihar Desai: 25 years of imatinib / Brian J. Druker, cancer, imatinib, Nihar Desai, OncoDaily, Oncology

oncodaily.com

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Nihar Desai MD, DM @nihardesai7.bsky.social · Feb 19

Sorry, what? This happens??

Nihar Desai MD, DM @nihardesai7.bsky.social · Feb 19

This 35 yr old man is always tired 😭

You find 👇🏽 on clinical examination. He also has bradycardia 🫀

Ddx?
Management?

📸 @nejm.org

Nihar Desai MD, DM @nihardesai7.bsky.social · Feb 12

Out now in Blood Advances 🙌🏽

Our work from Princess Margaret Cancer Centre evaluating the role of PTCy in matched sibling donor allogeneic transplantation!

Also read this excellent commentary by my good friend @nicogagelmann.bsky.social 👇🏽

ashpublications.org/bloodadvance...

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Nihar Desai MD, DM @nihardesai7.bsky.social · Feb 7

I am pleased to present 3 posters and chair a session at the EBMT annual meeting in Florence 🙌🏽

@hansbmt.bsky.social

Nihar Desai MD, DM @nihardesai7.bsky.social · Feb 5

What doesn’t evolve, goes extinct!!

If you don’t adapt new data, you’ll never improve patient care. No study is perfect, and none ever will be. What matters is critical appraisal of available literature and adapting it to improve patient care 🙏🏽

Nihar Desai MD, DM @nihardesai7.bsky.social · Feb 5

Can a D-dimer be used to diagnose DVT/PE?

NOOOOOOOOOOOOOOOOOOOO!

What else ⤴️D-dimer?
•Any infection
•Any inflammation
•Old age
•Cancer

Remember, D-dimer is a very sensitive test but NOT a very specific test 🙌🏽

Nihar Desai MD, DM @nihardesai7.bsky.social · Feb 2

It's not just the ⤵️EPO that causes anemia in patients with CKD

CKD = inflammation = ⤴️Hepcidin = ⤵️iron absorption = anemia

Blood loss during dialysis = iron deficiency anemia

CKD = ⤴️Uremic toxins = ⤵️red cell production

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Nihar Desai MD, DM @nihardesai7.bsky.social · Feb 2

Anemia in CKD 👇🏽

We all know that CKD = ⤵️EPO

What's the mechanism?

The interstitial cells transdifferentiate into MYOFIBROBLASTS instead of EPO producing cells

⤵️ EPO producing cells = ⤵️EPO = Anemia 👇🏽

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Nihar Desai MD, DM @nihardesai7.bsky.social · Jan 31

Fever + cytopenias + organomegaly ➡️ think HLH!

If you don't suspect HLH, you'll miss HLH 🙌🏽

Nice figure by Nguyen et al 👇🏽

doi.org/10.1038/s122...

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Nihar Desai MD, DM @nihardesai7.bsky.social · Jan 14

The magic of stem cell transplantation for aplastic anemia 💪🏽

Before ➡️ After

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Nihar Desai MD, DM @nihardesai7.bsky.social · Jan 13

📢 Happy to speak about the impact of ABO status on engraftment and survival after allogeneic transplant in the PTCy era at the Cochin Hematology Group annual meeting 🙌🏽

Nihar Desai MD, DM @nihardesai7.bsky.social · Jan 13

Ivermectin is a great drug for parasitic infections but it does NOT cure cancer.

Sincerely,
An oncologist

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Reposted by Nihar Desai MD, DM

NEJM.org @nejm.org · Jan 10

In a single-group, single-center study, clearance of driver mutations 30 days after bone marrow transplantation predicted long-term disease-free survival in patients with myelofibrosis. Read the full study results: nej.md/4fQNdKn

#MedSky

Clearance of Driver Mutations after Transplantation for Myelofibrosis | NEJM

Allogeneic hematopoietic stem-cell transplantation is the only curative treatment for myelofibrosis. Driver mutations are the pathophysiological hallmark of the disease, but the role of mutation cl...

nej.md

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Reposted by Nihar Desai MD, DM

Hank Green @hankgreen.bsky.social · Jan 11

I do feel like we forget that a mere 100 years ago 20% of children in America just fucking died.

260 1.2K 12K

Nihar Desai MD, DM @nihardesai7.bsky.social · Jan 10

Now that the USA sucks, have you considered moving to USB?

Nihar Desai MD, DM @nihardesai7.bsky.social · Jan 10

Remember, the mentor - mentee relationship is a two way street. Mentees must learn to deliver what they've promised 🙌🏽

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Nihar Desai MD, DM @nihardesai7.bsky.social · Jan 10

A mentor need not be your Prof. It could be anyone! A person you meet online, a friend, a senior colleague. It's also possible to have multiple mentors 🙏🏽

Nihar Desai MD, DM @nihardesai7.bsky.social · Jan 5

I ❤️ road trips!

Nihar Desai MD, DM @nihardesai7.bsky.social · Jan 2

Walking in to 2025 with my ❤️