Nick Steele
@njsteele01.bsky.social
Neuroscience researcher at Duke University 🧠 Researching pyschopathology and brain network organization.
/1 Here's yet another study on the thalamus in PTSD! We show that PTSD patients display different patterns of connectivity between the thalamus & cortex. Different nuclei displayed different patterns of altered RSFC..
#neuroskyence #neuroscience #science #fMRI
www.sciencedirect.com/science/arti...
#neuroskyence #neuroscience #science #fMRI
www.sciencedirect.com/science/arti...
Disrupted thalamocortical functional connectivity and canonical resting-state network integration in posttraumatic stress disorder
The thalamus exhibits widespread connectivity to the entire cortical mantle, yet distinct thalamic subregions possess unique connectivity profiles and…
www.sciencedirect.com
January 14, 2026 at 5:56 PM
/1 Here's yet another study on the thalamus in PTSD! We show that PTSD patients display different patterns of connectivity between the thalamus & cortex. Different nuclei displayed different patterns of altered RSFC..
#neuroskyence #neuroscience #science #fMRI
www.sciencedirect.com/science/arti...
#neuroskyence #neuroscience #science #fMRI
www.sciencedirect.com/science/arti...
Reposted by Nick Steele
A video of ICE agents conducting door-to-door searches today in Minneapolis
The homeowner requests a warrant repeatedly, is told they don't require one, then is told they're getting it, then the agents storm in anyway
They also point a taser at her to try and disrupt filming
The homeowner requests a warrant repeatedly, is told they don't require one, then is told they're getting it, then the agents storm in anyway
They also point a taser at her to try and disrupt filming
January 12, 2026 at 1:42 AM
A video of ICE agents conducting door-to-door searches today in Minneapolis
The homeowner requests a warrant repeatedly, is told they don't require one, then is told they're getting it, then the agents storm in anyway
They also point a taser at her to try and disrupt filming
The homeowner requests a warrant repeatedly, is told they don't require one, then is told they're getting it, then the agents storm in anyway
They also point a taser at her to try and disrupt filming
Reposted by Nick Steele
“The Party told you to reject the evidence of your eyes and ears. It was their final, most essential command.” —George Orwell (1984)
January 8, 2026 at 3:32 PM
“The Party told you to reject the evidence of your eyes and ears. It was their final, most essential command.” —George Orwell (1984)
Reposted by Nick Steele
“'The guy, I’m telling him like, "Please step off the school grounds," and this dude comes up and bumps into me and then tells me that I pushed him, and he knocked me down,' an official at Roosevelt High School said. 'They don’t care. They’re just animals. I’ve never seen people behave like this.'"
Minneapolis schools cancel classes after Border Patrol clash disrupts dismissal at Roosevelt
Minneapolis schools closed for the week citing safety concerns after an encounter involving armed Border Patrol agents near Roosevelt High School.
www.mprnews.org
January 8, 2026 at 2:09 PM
“'The guy, I’m telling him like, "Please step off the school grounds," and this dude comes up and bumps into me and then tells me that I pushed him, and he knocked me down,' an official at Roosevelt High School said. 'They don’t care. They’re just animals. I’ve never seen people behave like this.'"
Reposted by Nick Steele
Thank you to everyone who came out and helped spread the word. Thousands of Minnesotans gathered tonight for a vigil honoring Renee Good, who was murdered by ICE agents. Let’s get ICE out of MN!
January 8, 2026 at 12:59 AM
Thank you to everyone who came out and helped spread the word. Thousands of Minnesotans gathered tonight for a vigil honoring Renee Good, who was murdered by ICE agents. Let’s get ICE out of MN!
Reposted by Nick Steele
This paper had a pretty shocking headline result (40% of voxels!), so I dug into it, and I think it is wrong. Essentially: they compare two noisy measures and find that about 40% of voxels have different sign between the two. I think this is just noise!
Would love to hear expert views on this paper. It appears to show that the operationalization of brain activity the field has relied on for 3 decades—the BOLD response—is not actually a sensible measure of brain activity.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
BOLD signal changes can oppose oxygen metabolism across the human cortex - Nature Neuroscience
Using quantitative brain imaging, the authors show opposite fMRI BOLD signal to metabolic activity due to variable oxygen extraction across the human cortex. This questions the canonical interpretatio...
www.nature.com
January 5, 2026 at 5:22 PM
This paper had a pretty shocking headline result (40% of voxels!), so I dug into it, and I think it is wrong. Essentially: they compare two noisy measures and find that about 40% of voxels have different sign between the two. I think this is just noise!
Reposted by Nick Steele
The calendar changes— on the one hand, an entirely arbitrary chronological signifier. On the other, an absolutely necessary chance to catch our breath, renew our energies, and look ahead. Let’s go!
January 1, 2026 at 5:44 AM
The calendar changes— on the one hand, an entirely arbitrary chronological signifier. On the other, an absolutely necessary chance to catch our breath, renew our energies, and look ahead. Let’s go!
Reposted by Nick Steele
New paper in Imaging Neuroscience by Hecheng Jin, Ting Xu, et al:
Is Pearson’s correlation coefficient enough for functional connectivity in fMRI?
doi.org/10.1162/IMAG...
Is Pearson’s correlation coefficient enough for functional connectivity in fMRI?
doi.org/10.1162/IMAG...
December 8, 2025 at 11:20 PM
New paper in Imaging Neuroscience by Hecheng Jin, Ting Xu, et al:
Is Pearson’s correlation coefficient enough for functional connectivity in fMRI?
doi.org/10.1162/IMAG...
Is Pearson’s correlation coefficient enough for functional connectivity in fMRI?
doi.org/10.1162/IMAG...
How is the thalamus impacted by trauma? The thalamus is more than a relay - it is a key node in perceptual, cognitive, and affective processing circuits. We found that the limbic thalamus has lower volume in both PTSD and MDD, while the sensorimotor thalamus has lower volume in PTSD only /1
Volumetric Differences of Thalamic Nuclei are Associated with Post-Trauma Psychopathology
Previous investigations of whole thalamus and thalamic nuclei volumes in post-trauma
psychopathology have been sparse, limited in scope, and yielded inconsistent results.
To address this, volumetric e...
www.biologicalpsychiatrycnni.org
November 12, 2025 at 4:22 AM
How is the thalamus impacted by trauma? The thalamus is more than a relay - it is a key node in perceptual, cognitive, and affective processing circuits. We found that the limbic thalamus has lower volume in both PTSD and MDD, while the sensorimotor thalamus has lower volume in PTSD only /1
Working with @enigmabrains.bsky.social datasets or conducting meta- or mega-analyses? Check out our software package, IBMMA, designed to facilitate analysis of neuroimaging big data. Excited the toolbox manuscript is now out! @ptenigma.bsky.social @jennistevens.bsky.social doi.org/10.1016/j.ne...
Image-Based Meta- and Mega-Analysis (IBMMA): A Unified Framework for Large-Scale, Multi-Site, Neuroimaging Data Analysis
The increasing scale and complexity of neuroimaging datasets aggregated from multiple study sites present substantial analytic challenges, as existing…
www.sciencedirect.com
October 23, 2025 at 6:23 PM
Working with @enigmabrains.bsky.social datasets or conducting meta- or mega-analyses? Check out our software package, IBMMA, designed to facilitate analysis of neuroimaging big data. Excited the toolbox manuscript is now out! @ptenigma.bsky.social @jennistevens.bsky.social doi.org/10.1016/j.ne...