Noah Reid
@noahreid.bsky.social
1.5K followers 1.2K following 450 posts
Computational Biology Core at the University of Connecticut. Genomics, bioinformatics, evolution. Also nature, natural history. A little too into birding. https://scholar.google.com/citations?user=IbPpB9sAAAAJ&h
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noahreid.bsky.social
Maybe time to rewatch The Wire
junoryleejournalism.com
David Simon, creator of ‘The Wire’, being interviewed by Ari Shapiro (NPR)
SHAPIRO: OK, so you've spent your career creating television without Al, and I could imagine today you thinking, boy, I wish I had had that tool to solve those thorny problems...
SIMON: What?
SHAPIRO: ...Or saying...
SIMON: You imagine that?
SHAPIRO: ...Boy, if that had existed, it would have screwed me over.
SIMON: I don't think Al can remotely challenge what writers do at a fundamentally creative level.
SHAPIRO: But if you're trying to transition from scene five to scene six, and you're stuck with that transition, you could imagine plugging that portion of the script into an Al and say, give me 10 ideas for how to transition this.
SIMON: I'd rather put a gun in my mouth.
noahreid.bsky.social
look, I don't want people going to jail for weed, but is there some compromise position that makes it so I don't have to smell weed 100% of the time in any populated part of the country?
noahreid.bsky.social
The number one thing I miss about being 20 is the ability to sleep like the dead for 12 straight hours.
noahreid.bsky.social
we started using Starfish to look at data on our HPC. it's pretty amazing. getting a high level view of storage and being able to immediately see problems like, say, 60TB of old nextflow work directories floating around is fantastic.
noahreid.bsky.social
"Oceans are a spectrum" is an assault on western civilization.
noahreid.bsky.social
S: well just don't guess if there's a red storm trooper in it.
Me: stop, you're telling me too much! You just told me there's a red storm trooper!
S: I told you not to guess that! ....<sad voice> oh no, I spoiled it.
noahreid.bsky.social
S: I'll never tell you what kind of Lego set it is.
Me: ...
S: I'll never tell you what kind of guys are in the star wars Lego set we got you.
Me: kid, you're not supposed to tell me this!
noahreid.bsky.social
Reminds me of 2020, with then 4yo:

S: we got you a present for your birthday, daddy!
Me: great! I can't wait to see what it is.
S: I'm never going to tell you what it is.
Me: very good. Keep it a surprise.
philippbayer.bsky.social
I was wondering whether ChatGPT could identify species from drawings, but it said 'no for safety reasons, you can absolutely tell me context (for example: “this jellyfish is small, transparent, and causes Irukandji syndrome”)' -
guess what, I uploaded an Irukandji image
noahreid.bsky.social
I hear what you're probably saying and I could totally re-record the video and either not lie or just make it shorter and one day I probably will.
noahreid.bsky.social
My worst trait as an instructor of online courses is my tendency to start demo videos with "this will be a short video about X" and then the demonstration is absolutely not short.

I console myself with the fact that students can see the progress bar and know that I am lying.
noahreid.bsky.social
Can someone explain to me what is happening here
buffalobillsnfl.bsky.social
Ornithology is all about the process.

#GoBills | #BillsMafia
Reposted by Noah Reid
anaignatieva.bsky.social
Delighted that our paper about the distribution of genomic spans of clades/edges in genealogies (ARGs), and using this for detecting inversions and other SVs (and other phenomena that cause local disruption of recombination) is out in MBE academic.oup.com/mbe/article/... (1/n)
The Length of Haplotype Blocks and Signals of Structural Variation in Reconstructed Genealogies
Abstract. Recent breakthroughs have enabled the accurate inference of large-scale genealogies. Through modelling the impact of recombination on the correla
academic.oup.com
noahreid.bsky.social
I see nobody answered this question in 2023! Do we know now? I was able to download data from SRA last night, but will access continue?
noahreid.bsky.social
RE NCBI and the shutdown: I was able to grab some SRA data I needed last night. Is there any reason to think that NCBI databases might become inaccessible?
Reposted by Noah Reid
noahreid.bsky.social
UConn's CBC is offering a virtual workshop on ChIP and ATAC seq at the end of October.
Join us Oct. 28–30 for a Virtual ChIP-Seq / ATAC-Seq Workshop! 🧬

📅 10 AM – 2 PM EST
💻 Live on Zoom + recordings
💰 $500 ($400 UConn affiliates)

Register: bioinformatics.uconn.edu/cbc-workshops/

#ChIPSeq #ATACSeq #Bioinformatics #Workshop
noahreid.bsky.social
I'm confused because I genuinely thought the types of christians who fret about the antichrist see end of the world as a good thing.
Reposted by Noah Reid
yun-s-song.bsky.social
We are excited to share GPN-Star, a cost-effective, biologically grounded genomic language modeling framework that achieves state-of-the-art performance across a wide range of variant effect prediction tasks relevant to human genetics.
www.biorxiv.org/content/10.1...
(1/n)
noahreid.bsky.social
yeah, I guess it's not digging or trying to move it, just poking at it repeatedly. super weird and interesting and very cool looking! thanks for sharing!
noahreid.bsky.social
that's amazing. I wonder if to a ghost crab an object or mound of sand right next to the burrow is viewed as a threat because it obscures their view of possible predators.
Reposted by Noah Reid
sarahmackattack.bsky.social
I wanted to get a video of this ghost crab but every time I got close to their hole they scuttled back in, so I tried getting clever with it. I made a little sandcastle and shoved my phone into it, hit record, and walked away. Crab was VERY suspicious of this addition to their environment.
noahreid.bsky.social
real basic bioinfo q:

bioawk has a function `meanqual` that takes the arithmetic mean of phred-scaled base qualities. this is the geometric mean of the actual base error probabilities. why would anyone actually want that vs the arithmetic mean which can be interpreted as expected # errors?
noahreid.bsky.social
I'm not a big boycotter, but we canceled Hulu/Disney+ over the Kimmel thing. This is straightforward authoritarianism.
noahreid.bsky.social
In my fantasy world, the late night hosts are planning to get together on one of their shows and just do an hour long MAGA themed "aristocrats" riff.
noahreid.bsky.social
for me it's R in a terminal window.