Paulina Wanrooij
@paulinawanrooij.bsky.social
Research group leader at Umeå University, interested in mitochondrial DNA instability and its signaling to the rest of the cell.
🚨 Postdoc position open!
Join us at Umeå University to study proteins that maintain mitochondrial DNA stability.
2-year fellowship | International research environment | Apply now!
🔗 umustipendie.varbi.com/en/what:job/...
#Postdoc #Mitochondria #Biochemistry #AcademicJobs
Join us at Umeå University to study proteins that maintain mitochondrial DNA stability.
2-year fellowship | International research environment | Apply now!
🔗 umustipendie.varbi.com/en/what:job/...
#Postdoc #Mitochondria #Biochemistry #AcademicJobs
Postdoctoral fellowship (2 years) to study proteins that maintain mitochondrial DNA
The Department of Medical Biochemistry and Biophysics is offering a postdoctoral scholarship within the project "Signaling of mitochondrial DNA instability". The scholarship is full-time for two year
umustipendie.varbi.com
October 22, 2025 at 11:20 AM
🚨 Postdoc position open!
Join us at Umeå University to study proteins that maintain mitochondrial DNA stability.
2-year fellowship | International research environment | Apply now!
🔗 umustipendie.varbi.com/en/what:job/...
#Postdoc #Mitochondria #Biochemistry #AcademicJobs
Join us at Umeå University to study proteins that maintain mitochondrial DNA stability.
2-year fellowship | International research environment | Apply now!
🔗 umustipendie.varbi.com/en/what:job/...
#Postdoc #Mitochondria #Biochemistry #AcademicJobs
Our newest paper on mitochondrial Topoisomerase 1 shows that Top1mt has only weak endoribonuclease activity and it therefore does not often generate deletions at incorporated ribonucleotides. This helps explain why ribonucleotides are tolerated in mtDNA. Read more:
academic.oup.com/nar/article-...
academic.oup.com/nar/article-...
The low endoribonuclease activity and lack of rNMP preference of human mitochondrial topoisomerase 1 protect against ribonucleotide-dependent deletions
Abstract. The incorporation of ribonucleotides (rNMPs) into the nuclear genome leads to severe genomic instability, including strand breaks and short 2–5 b
academic.oup.com
June 8, 2025 at 11:31 AM
Our newest paper on mitochondrial Topoisomerase 1 shows that Top1mt has only weak endoribonuclease activity and it therefore does not often generate deletions at incorporated ribonucleotides. This helps explain why ribonucleotides are tolerated in mtDNA. Read more:
academic.oup.com/nar/article-...
academic.oup.com/nar/article-...
Only just over a week left to apply for a postdoc position in our lab - if you are passionate about mtDNA maintenance and biochemistry or signaling, here is your chance!
Hello fellow mitochondriacs! Are you passionate about mtDNA? We now offer a 2-year postdoc opportunity for studies of mtDNA instability and its signaling. Apply by May 18th to join our international team in exotic Umeå. Please share!
www.umu.se/en/work-with...
www.umu.se/en/work-with...
Postdoctoral fellowship (2 years) to study mitochondrial DNA stability
www.umu.se
May 9, 2025 at 4:57 PM
Only just over a week left to apply for a postdoc position in our lab - if you are passionate about mtDNA maintenance and biochemistry or signaling, here is your chance!
Two mtDNA papers of ours in one PNAS issue:
#1 on the Y951N patient mutation of PolG, heroically spear-headed by Josefin Forslund
#2 revealing surprising dNTP imbalance & subsequent mtDNA depletion in RRM2B-deficient mice, a great collaboration with the Chabes lab
www.pnas.org/toc/pnas/122...
#1 on the Y951N patient mutation of PolG, heroically spear-headed by Josefin Forslund
#2 revealing surprising dNTP imbalance & subsequent mtDNA depletion in RRM2B-deficient mice, a great collaboration with the Chabes lab
www.pnas.org/toc/pnas/122...
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
www.pnas.org
April 22, 2025 at 6:41 PM
Two mtDNA papers of ours in one PNAS issue:
#1 on the Y951N patient mutation of PolG, heroically spear-headed by Josefin Forslund
#2 revealing surprising dNTP imbalance & subsequent mtDNA depletion in RRM2B-deficient mice, a great collaboration with the Chabes lab
www.pnas.org/toc/pnas/122...
#1 on the Y951N patient mutation of PolG, heroically spear-headed by Josefin Forslund
#2 revealing surprising dNTP imbalance & subsequent mtDNA depletion in RRM2B-deficient mice, a great collaboration with the Chabes lab
www.pnas.org/toc/pnas/122...
Hello fellow mitochondriacs! Are you passionate about mtDNA? We now offer a 2-year postdoc opportunity for studies of mtDNA instability and its signaling. Apply by May 18th to join our international team in exotic Umeå. Please share!
www.umu.se/en/work-with...
www.umu.se/en/work-with...
Postdoctoral fellowship (2 years) to study mitochondrial DNA stability
www.umu.se
April 16, 2025 at 11:43 AM
Hello fellow mitochondriacs! Are you passionate about mtDNA? We now offer a 2-year postdoc opportunity for studies of mtDNA instability and its signaling. Apply by May 18th to join our international team in exotic Umeå. Please share!
www.umu.se/en/work-with...
www.umu.se/en/work-with...
Our newest paper on mtDNA instability signaling by Gustavo Carvalho, Tran Nguyen and Bruno Repolês et al is out: Activating AMPK improves pathological phenotypes due to mtDNA depletion - Carvalho - The FEBS Journal - Wiley Online Library febs.onlinelibrary.wiley.com/doi/full/10....
FEBS Press
In a cellular model of mitochondrial disease characterized by progressive mitochondrial DNA (mtDNA) depletion, we found that advancing mitochondrial dysfunction triggers the early and specific activa...
febs.onlinelibrary.wiley.com
February 9, 2025 at 8:31 AM
Our newest paper on mtDNA instability signaling by Gustavo Carvalho, Tran Nguyen and Bruno Repolês et al is out: Activating AMPK improves pathological phenotypes due to mtDNA depletion - Carvalho - The FEBS Journal - Wiley Online Library febs.onlinelibrary.wiley.com/doi/full/10....
Reposted by Paulina Wanrooij
We are hiring!
We're looking for a Postdoctoral Researcher to explore the dynamics of human mitochondrial DNA replication at the single-molecule level.
Review the details below👇or visit borjaibarralab.com 💻
We're looking for a Postdoctoral Researcher to explore the dynamics of human mitochondrial DNA replication at the single-molecule level.
Review the details below👇or visit borjaibarralab.com 💻
February 7, 2025 at 3:28 PM
We are hiring!
We're looking for a Postdoctoral Researcher to explore the dynamics of human mitochondrial DNA replication at the single-molecule level.
Review the details below👇or visit borjaibarralab.com 💻
We're looking for a Postdoctoral Researcher to explore the dynamics of human mitochondrial DNA replication at the single-molecule level.
Review the details below👇or visit borjaibarralab.com 💻