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pavelbarahtjan.bsky.social
Pavel Barahtjan
@pavelbarahtjan.bsky.social
250 followers 400 following 9 posts
Lipids | Membranes | Tardigrades | Chemical Biology | PostDoc @EPFL | MPICBG Alumnus
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Reposted by Pavel Barahtjan
nadlerlab.bsky.social
André Nadler @nadlerlab.bsky.social · 1d
Lipid imaging on the cover of @nature.com! Great times for lipid cell biology indeed. And a fantastic recognition of all the hard work by the team, especially Juan M. Iglesias-Artola and Kristin Böhlig (who made the cover). Link to article: www.nature.com/articles/s41...
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pavelbarahtjan.bsky.social
Pavel Barahtjan @pavelbarahtjan.bsky.social · 2d
I thinkt its one of those 'once in a lifetime' events
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Reposted by Pavel Barahtjan
jamessaenz.bsky.social
James Saenz @jamessaenz.bsky.social · 16d
🌶️ Lipids bring the heat 🔥

Lipids don’t just shape membranes, they influence cellular metabolism.

We show that tuning lipidome composition strongly alters metabolic heat flow in the minimal cell JCVI-Syn3B 🦠

Fantastic collaboration with Karim Fahmy’s lab (HZDR) 🎉

www.biorxiv.org/content/10.1...
Metabolic heat flow from the minimal cell JCVI-Syn3B reveals the lipidome-dependence of growth and metabolism
The cell membrane facilitates interactions with the environment and serves as an organizational platform for coordinating cellular processes, with lipids playing a central role in determining membrane...
www.biorxiv.org
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pavelbarahtjan.bsky.social
Pavel Barahtjan @pavelbarahtjan.bsky.social · 15d
Amazing news. Well deserved.
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Reposted by Pavel Barahtjan
mschuhmacher.bsky.social
Milena Schuhmacher @mschuhmacher.bsky.social · Sep 4
So honored to be awarded the ERC Starting Grant! I am very grateful for this support and looking forward to more exciting #lipidtime 🥳
Also, we will have positions available next year. So stay tuned!
erc.europa.eu
European Research Council (ERC) @erc.europa.eu · Sep 4
📣 The ERC Starting Grant call results are out!

Find out which early-career researchers will receive funding this year, what they will be investigating, where they will be based... plus lots of other #ERCStG facts & figures for 2025!

➡️ buff.ly/IsafuFh

#FrontierResearch 🇪🇺#EUfunded #HorizonEurope
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Reposted by Pavel Barahtjan
paveltomancak.bsky.social
paveltomancak.bsky.social @paveltomancak.bsky.social · Sep 4
We are all super happy and proud to see our work on the function and evolution of the #cephalic #furrow published in @nature.com. Let me say a few things about the background and history of this work on the #Evolution_of_Morphogenesis (1/12)
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Reposted by Pavel Barahtjan
giodang.bsky.social
Giovanni D’Angelo @giodang.bsky.social · Sep 3
Happy to share our work on uMAIA, a framework for building metabolomic atlases from mass spectrometry imaging.
With uMAIA, we mapped the lipidome of zebrafish development, uncovering spatially organized metabolic programs .
www.nature.com/articles/s41...
#developmentalbiology #MSI #lipidtime
Unified mass imaging maps the lipidome of vertebrate development
Nature Methods - uMAIA is an analytical framework designed to enable the construction of metabolic atlases at high resolution using mass spectrometry imaging data.
www.nature.com
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Reposted by Pavel Barahtjan
nadlerlab.bsky.social
André Nadler @nadlerlab.bsky.social · Aug 21
Out today in @nature.com: Together with the Honigmann, Shevchenko, Drobot and Hof labs, we present a general workflow for imaging the localization and transport of individual lipids in cells and mapping their metabolism.
www.nature.com/articles/s41...
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Reposted by Pavel Barahtjan
jeremybaskin.bsky.social
Jeremy Baskin @jeremybaskin.bsky.social · Aug 20
Quite a week for #lipidtime: phenomenal study using bifunctional lipid probes to quantify intracellular lipid transport from @nadlerlab.bsky.social and colleagues is now out @nature.com! www.nature.com/articles/s41...
Quantitative imaging of lipid transport in mammalian cells - Nature
Directional, non-vesicular lipid transport is responsible for fast, species-selective lipid sorting into organelle membranes.
www.nature.com
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Reposted by Pavel Barahtjan
mschuhmacher.bsky.social
Milena Schuhmacher @mschuhmacher.bsky.social · Aug 12
We are hiring!

If you are looking for a postdoc position and you are interested in signaling lipids and proteomics, come join us in beautiful Switzerland!

More information on www.epfl.ch/labs/gr-schu...
Open positions
GR-SCHUHMACHER
www.epfl.ch
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pavelbarahtjan.bsky.social
Pavel Barahtjan @pavelbarahtjan.bsky.social · May 29
Yeah, let's see if we can arrange something for when I'm in Tsuruoka at the end of June.
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pavelbarahtjan.bsky.social
Pavel Barahtjan @pavelbarahtjan.bsky.social · May 29
The world is small... Randomly found out that @mikelangelipid.bsky.social and I are both in Osaka, so we met up for some drinks and #lipidtime talk.
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Reposted by Pavel Barahtjan
ritamateus.bsky.social
Rita Mateus @ritamateus.bsky.social · May 13
Think biosensors that give absolute measurement values! So happy this is out :) congrats to everyone involved, especially @sascha-kuhn.bsky.social and @nadlerlab.bsky.social
nadlerlab.bsky.social
André Nadler @nadlerlab.bsky.social · May 13
Meet GEQO: Genetically-encoded biosensors for absolute small-molecule quantification in single cells brought to you by @sascha-kuhn.bsky.social. For simple absolute quantification of your favourite small molecule or ion, head on over to @bioarxiv and read our new preprint: doi.org/10.1101/2025...
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Reposted by Pavel Barahtjan
nadlerlab.bsky.social
André Nadler @nadlerlab.bsky.social · May 6
Why are biological membranes asymmetric, with different lipids in the two bilayer leaflets? Discovered in the 70s, lipid asymmetry is linked to many cellular processes, but why the cell needs it is largely unclear. @pavelbarahtjan.bsky.social addresses this question: www.biorxiv.org/content/10.1...
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Reposted by Pavel Barahtjan
nadlerlab.bsky.social
André Nadler @nadlerlab.bsky.social · May 13
Meet GEQO: Genetically-encoded biosensors for absolute small-molecule quantification in single cells brought to you by @sascha-kuhn.bsky.social. For simple absolute quantification of your favourite small molecule or ion, head on over to @bioarxiv and read our new preprint: doi.org/10.1101/2025...
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Reposted by Pavel Barahtjan
lipid.bsky.social
Coskun Lipid Cellar @ ZML Dresden @lipid.bsky.social · May 9
An amazing new enabling technology. Measurements of molecular size and shape on a chip. Couldn't be prouder of our friend Madhavi Krishnan of @ox.ac.uk this was and is one among the must fun collaborations I ever had. www.science.org/doi/10.1126/...
Measurements of molecular size and shape on a chip
Size and shape are critical discriminators between molecular species and states. We describe a microchip-based high-throughput imaging approach offering rapid and precise determination of molecular pr...
www.science.org
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pavelbarahtjan.bsky.social
Pavel Barahtjan @pavelbarahtjan.bsky.social · May 6
Really happy that my main PhD story is out! Huge thanks to everyone involved - especially @nadlerlab.bsky.social - for giving me the opportunity to work on this amazing topic.
nadlerlab.bsky.social
André Nadler @nadlerlab.bsky.social · May 6
Why are biological membranes asymmetric, with different lipids in the two bilayer leaflets? Discovered in the 70s, lipid asymmetry is linked to many cellular processes, but why the cell needs it is largely unclear. @pavelbarahtjan.bsky.social addresses this question: www.biorxiv.org/content/10.1...
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pavelbarahtjan.bsky.social
Pavel Barahtjan @pavelbarahtjan.bsky.social · May 5
Why not combining both? Glycosphingolipids can get pretty complex and important
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pavelbarahtjan.bsky.social
Pavel Barahtjan @pavelbarahtjan.bsky.social · May 5
Right :D but I didnt feel like optimising the prompt
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pavelbarahtjan.bsky.social
Pavel Barahtjan @pavelbarahtjan.bsky.social · May 5
Original image (colorised), well according to chatgpt
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pavelbarahtjan.bsky.social
Pavel Barahtjan @pavelbarahtjan.bsky.social · Mar 10
Amazing work! Of course LA is the answer to all questions :D
nadlerlab.bsky.social
André Nadler @nadlerlab.bsky.social · Mar 10
Are lipids actively sorted during clathrin mediated endocytosis like proteins? @mathilda95.bsky.social addresses this key open question together with our collaborators from the Honigmann and Modes labs using a new Lipid-STED workflow.
www.biorxiv.org/content/10.1...
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Reposted by Pavel Barahtjan
jean-maillat.bsky.social
jean-maillat.bsky.social @jean-maillat.bsky.social · Jan 16
Amazing review to learn about single-cell lipid biology ! Congratulations to all authors @antonino-asaro.bsky.social @Agostina Crotta Asis @giodang.bsky.social published in @cp-trendscellbio.bsky.social !

www.cell.com/trends/cell-...
Single cell lipid biology
Lipids are major cell constituents endowed with astonishing structural diversity. The pathways responsible for the assembly and disposal of different lipid species are energetically demanding, and gen...
www.cell.com
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