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Reposted by Milena Schuhmacher

GBM (Gesellschaft für Biochemie und Molekularbiologie) @gbmev.bsky.social · 23h

Registration open: 77. Mosbacher Kolloquium "More than lipidic barriers - New horizons in membrane biology" from March 25-28, 2026
lnkd.in/dgsW4c3

Scientific Organizers: Britta Brügger, Robert Ernst, André Nadler, Christian Ungermann
Early registration & poster abstracts until January 31, 2026

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Reposted by Milena Schuhmacher

Erdinc Sezgin @sciezgin.bsky.social · Sep 8

Previous preprint is now published in RSC Chemical Biology.
If you are interested in plasma membrane labeling, see the paper! 👇
pubs.rsc.org/en/content/a...

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Milena Schuhmacher @mschuhmacher.bsky.social · Sep 5

Thanks James!

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Milena Schuhmacher @mschuhmacher.bsky.social · Sep 5

Thank you so much Claudia!

Milena Schuhmacher @mschuhmacher.bsky.social · Sep 5

Thank you so much!

Milena Schuhmacher @mschuhmacher.bsky.social · Sep 5

Thank you so much André!

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Milena Schuhmacher @mschuhmacher.bsky.social · Sep 4

So honored to be awarded the ERC Starting Grant! I am very grateful for this support and looking forward to more exciting #lipidtime 🥳
Also, we will have positions available next year. So stay tuned!

European Research Council (ERC) @erc.europa.eu · Sep 4

📣 The ERC Starting Grant call results are out!

Find out which early-career researchers will receive funding this year, what they will be investigating, where they will be based... plus lots of other #ERCStG facts & figures for 2025!

➡️ buff.ly/IsafuFh

#FrontierResearch 🇪🇺#EUfunded #HorizonEurope

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Reposted by Milena Schuhmacher

Science Magazine @science.org · Aug 19

In the new book Labwork to Leadership, chemist Jen Heemstra offers actionable leadership advice to principal investigators.

Read the #ScienceBooks Review: https://scim.ag/4mljVr1

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Reposted by Milena Schuhmacher

tafesselab.bsky.social @tafesselab.bsky.social · Aug 12

Have you published lipid-protein interactome data? Please let us know, we’d love to include it in the repository. The goal is to build a centralized hub for the scientific community.

Huge thanks to Gaelen Guzman, a graduate student/postdoc in the lab who built it from scratch.

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Reposted by Milena Schuhmacher

André Nadler @nadlerlab.bsky.social · Aug 21

Many thanks Helge!

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Milena Schuhmacher @mschuhmacher.bsky.social · Aug 21

Fantastic to finally see this story out!!! What a tremendous team effort, so proud to be part of it and congratulations to everyone involved!!!

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Milena Schuhmacher @mschuhmacher.bsky.social · Aug 12

We are hiring!

If you are looking for a postdoc position and you are interested in signaling lipids and proteomics, come join us in beautiful Switzerland!

More information on www.epfl.ch/labs/gr-schu...

Open positions

GR-SCHUHMACHER

www.epfl.ch

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Reposted by Milena Schuhmacher

Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · Jun 26

Novel Research in Biological Artificial Intelligence: Expressions of interest and nominations for a Max Planck Director to lead research in the field of Biological Artificial Intelligence @mpi-cbg.de and @csbdresden.bsky.social. More information: www.mpi-cbg.de/news-outreac...

Novel Research in Biological Artificial Intelligence

Expressions of interest and nominations for a Max Planck Director to lead research in the field of Biological Artificial Intelligence.

www.mpi-cbg.de

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Reposted by Milena Schuhmacher

Helena Klara Jambor @helenajambor.bsky.social · Jun 18

I gave in! After students asking for it, I now made a simple figure design checklist.
To help all scientists w/o graphic skills create clear, accessible, and truthful charts!
-> Out in @nature Cell Biology: rdcu.be/erwl4

#DataVisualization #PhD #SciComm

Thx for review @bethcimini.bsky.social + 2

A checklist for designing and improving the visualization of scientific data

Nature Cell Biology - Creating clear and engaging scientific figures is crucial to communicate complex data. In this Comment, I condense principles from design, visual perception and data...

rdcu.be

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Reposted by Milena Schuhmacher

Spirochrome @spirochrome.com · Jun 17

New preprint by @kjohnsson.bsky.social lab!

A new split Halotag system with higher affinity of the complements + lower background. The system works with our SiR-CA & CPY-CA halotag ligands and enables STED imaging or FLIM multiplexing.

The short 14 aa tag Hpep enables easy cloning free CRISPR-KI.

schematic illustration of protein labeling using the spontaneous self-complementing peptide protein split-HaloTag system. POI: protein of interest

Pairwise combination of Hpep11 (TOM20-tagged) with the other three Hpep variants 8, 9 and 10 (H2B-tagged) for FLIM multiplexing. The total fluorescence intensity composite, the two separated species and their corresponding wavelet-filtered phasor plot used for species separation are presented.

Live-cell confocal imaging of histone H2B type-2E-Hpep11 CRISPR KI cell lines after 2-hours labeling with the specified CA- ligand [100 nM]. Images were taken with optimal image acquisition parameter for each dye. Scale bar: 50 μm.

(a) Confocal laser scanning microscopy (CLSM) and STED images of mitochondria in U2OS cells coexpressing cpHaloΔ3 and TOM20-Hpep, either overexpressed or endogenously tagged. Scale bar: 1 μm. Pixel intensities scaled according to reference bar. (b) Representative CLSM, STED images of the CRISPR/Cas9 KI cells expressing TOM20 tagged with intact HaloTag (upper) or Hpep11 (bottom). (c) Intensity profiles along mitochondrial tubules (red and blue lines in b). Scale bar: 2 μm. (d) Representative CLSM and STED images of endogenous Hpep11-tagged clathrin with cpHaloΔ3 coexpression. Scale bar: 10 μm (overview) and 2 μm (magnification). (e) Representative CLSM, STED
images of endogenously tagged tubulin beta 4B with Hpep11. Scale bar: 10 μm (overview) and 2 μm (magnification). (f) Intensity profiles along tubulin filaments (red and blue lines in e) Means ± s.d. of the filament diameters were calculated as full width at half maximum (FWHM) from n=20 microtubule filaments, ≥ 2 images. A slight increase in cytosolic signal was noted in cells tagged with split-HaloTagat TUBB4B, compared to cells tagged with the full-length HaloTag, which may result from the presence of unbound but labeled cpHaloΔ3. All images were acquired after labeling with CA-SiR [100 nM] for one hour.

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Martin Weigert @maweigert.bsky.social · Jun 6

Out today in @natmethods.nature.com : Spotiflow, our transcript localization method for imaging-based spatial transcriptomics. Led by amazing PhD student @albertdm.bsky.social, joint work w @gioelelamanno.bsky.social at EPFL / @scadsai.bsky.social
www.nature.com/articles/s41...
rdcu.be/epIB7

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Reposted by Milena Schuhmacher

Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦ @dudinlab.bsky.social · Jun 10

90% of you probably don’t need to read this.
But maybe some of you are curious & 10% will feel seen. Or a little less alone. This isn’t about seeking sympathy.
It’s about sharing something hard to say out loud;
partly to heal, partly in case someone needs to hear it too. (1/3)
tinyurl.com/DudinO

Omaya Dudin

Interview with Omaya Dudin, who uses Ichthyosporea as models to study how and why unicellular organisms evolved multicellularity at the University of Geneva.

www.cell.com

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Reposted by Milena Schuhmacher

Sphingolipid Biology @slbiology.bsky.social · Jun 1

Over 150 participants from 23 countries came to Varna, Bulgaria for the 2025 FEBS Special Meeting/13th ICC. Five days of outstanding science, networking, socializing, and community! We are grateful to all the sponsors and look forward to the next one!

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Reposted by Milena Schuhmacher

Bianca Schrul @biancaschrul.bsky.social · May 14

The abstract submission deadline for the 2nd edition of our #EMBOLipidDroplets Workshop (21-26 September 2025) is approaching.

Check out the agenda with an amazing lineup of speakers and submit your abstract before 10 June 2025!

@embo.org
@biologists.bsky.social

meetings.embo.org/event/25-lip...

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Milena Schuhmacher @mschuhmacher.bsky.social · Apr 9

Thank you so much for your visit Jeremy, it was fantastic to have you here in Lausanne!

Jeremy Baskin @jeremybaskin.bsky.social · Apr 9

Bonjour et au revoir, Lausanne! And a big merci to @mschuhmacher.bsky.social for hosting me for a memorable day of engaging #lipidtime and protein engineering discussions at EPFL!

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Reposted by Milena Schuhmacher

Michelle Frei @michellefrei17.bsky.social · Apr 8

My lab at @ethzurich.bsky.social is looking for a motivated PhD student. We develop chemical tools for advanced fluorescence microscopy 🔬 and work at the interface of synthetic chemistry ⚗️ and protein engineering 🦠. Sharing with skilled Master students appreciated. More info at tinyurl.com/2dbjk5ty

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André Nadler @nadlerlab.bsky.social · Mar 10

Are lipids actively sorted during clathrin mediated endocytosis like proteins? @mathilda95.bsky.social addresses this key open question together with our collaborators from the Honigmann and Modes labs using a new Lipid-STED workflow.
www.biorxiv.org/content/10.1...

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Reposted by Milena Schuhmacher

Spirochrome @spirochrome.com · Mar 4

📢New product launch:

SPY555-FastAct_X:

✅ Improved actin ligand captures very fast actin dynamics
✅ No toxicity
✅ High brightness
✅ Low phototoxicity
✅ High photoblueing & bleaching resistance

spirochrome.com/product/spy5...

Image: @lindawedemann.bsky.social from @mschuhmacher.bsky.social lab

HeLa cells labeled with SPY555-FastAct_X. The picture is fluorescence micrograph showing the actin cytoskeleton as straight stress Fibers as well as some fainter mesh-like actin fibers. Image kindly provided by Linda Wedemann from the Schumacher group at EPFL, Switzerland.

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Reposted by Milena Schuhmacher

Kai Johnsson @kjohnsson.bsky.social · Feb 7

Check out our new fluorescent probe for imaging f-actin dynamics: 𝗦𝗶𝗥-𝗫𝗔𝗰𝘁𝗶𝗻: 𝗔 𝗳𝗹𝘂𝗼𝗿𝗲𝘀𝗰𝗲𝗻𝘁 𝗽𝗿𝗼𝗯𝗲 𝗳𝗼𝗿 𝗶𝗺𝗮𝗴𝗶𝗻𝗴 𝗮𝗰𝘁𝗶𝗻 𝗱𝘆𝗻𝗮𝗺𝗶𝗰𝘀 𝗶𝗻 𝗹𝗶𝘃𝗲 𝗰𝗲𝗹𝗹𝘀 www.biorxiv.org/content/10.1...
Thank you @veselin-nasufovic.bsky.social

SiR-XActin: A fluorescent probe for imaging actin dynamics in live cells

Imaging actin-dependent processes in live cells is important for understanding numerous biological processes. However, currently used natural-product based fluorescent probes for actin filaments affec...

www.biorxiv.org

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Reposted by Milena Schuhmacher

André Nadler @nadlerlab.bsky.social · Jan 31

It’s incredibly hard to study lipids in biological membranes on the nanoscale. You need near-perfect information on both membrane ultrastructure and lipid density, which usually isn’t attainable. Lipid-CLEM brought to you by @mathilda95.bsky.social changes that.
www.biorxiv.org/content/10.1...

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