Patrick
@plferree.bsky.social
Philosophy of science | biomedicine
Reposted by Patrick
Lots of great content in the latest newsletter from the Society for Philosophy of Science in Practice (SPSP is so good at fostering community). If you scroll all the way to the last feature I pour my heart out in the Proust Questionnaire. So good of Saana Jukola to give me the opportunity 🙏
ok, so I'm in serious procrastination mode, which led me to read the SPSP-newletter cover to cover, enjoying the interview with @annaalexandrova.bsky.social (among other things)!
sway.cloud.microsoft/Et71m6wUBR3w...
Over and out
Please call me out if you see me on here again today
#SPSP
sway.cloud.microsoft/Et71m6wUBR3w...
Over and out
Please call me out if you see me on here again today
#SPSP
SPSP Newsletter # 24
November 2025
sway.cloud.microsoft
November 25, 2025 at 7:08 PM
Lots of great content in the latest newsletter from the Society for Philosophy of Science in Practice (SPSP is so good at fostering community). If you scroll all the way to the last feature I pour my heart out in the Proust Questionnaire. So good of Saana Jukola to give me the opportunity 🙏
Reposted by Patrick
🎄 Day 4 of the 24 Days of Development ✨🧬
In 1984, Drosophila homeotic genes were found to be conserved across animals, including humans 🧬🐸. This article highlights a shared genetic toolkit for embryonic development 🔬🌟🎁 doi.org/10.1016/j.yd...
In 1984, Drosophila homeotic genes were found to be conserved across animals, including humans 🧬🐸. This article highlights a shared genetic toolkit for embryonic development 🔬🌟🎁 doi.org/10.1016/j.yd...
December 4, 2025 at 9:44 PM
🎄 Day 4 of the 24 Days of Development ✨🧬
In 1984, Drosophila homeotic genes were found to be conserved across animals, including humans 🧬🐸. This article highlights a shared genetic toolkit for embryonic development 🔬🌟🎁 doi.org/10.1016/j.yd...
In 1984, Drosophila homeotic genes were found to be conserved across animals, including humans 🧬🐸. This article highlights a shared genetic toolkit for embryonic development 🔬🌟🎁 doi.org/10.1016/j.yd...
Reposted by Patrick
'Here, we present a multi-organ single-cell atlas encompassing 23 fetal and adult organs, integrating scRNA-seq & scTCR-seq fm over 2.8 million immune cells across 15 second-trimester fetal & 4 adult donors.'
#Immunology
#Immunology
Systemic immune activity occurs during human immune system maturation
Profiling of immune cells from consecutive developmental time points in second-trimester
fetuses and adults reveals that immune activation, immune tolerance, and hematopoiesis
occur in a systemic way ...
www.cell.com
October 30, 2025 at 10:26 PM
'Here, we present a multi-organ single-cell atlas encompassing 23 fetal and adult organs, integrating scRNA-seq & scTCR-seq fm over 2.8 million immune cells across 15 second-trimester fetal & 4 adult donors.'
#Immunology
#Immunology
Reposted by Patrick
If you’re interested in practicing the philosophy of science in practice why not come along to an online workshop “the philosophy of science in practice - in practice”? #philsci
October 8, 2025 at 1:01 PM
If you’re interested in practicing the philosophy of science in practice why not come along to an online workshop “the philosophy of science in practice - in practice”? #philsci
Reposted by Patrick
Very saddened to hear of John Gurdon’s passing. I’ve been lucky enough to interact with him at multiple points through my career - from undergrad lectures, through his position as former Chair of @biologists.bsky.social’s Board of Directors, and as an author at @dev-journal.bsky.social.
Nobel Laureate Professor Sir John Gurdon dies aged 92
It is with great sadness that the University shares the news of the death of Professor Sir John Gurdon, founder of the Gurdon Institute.
www.cam.ac.uk
October 7, 2025 at 5:40 PM
Very saddened to hear of John Gurdon’s passing. I’ve been lucky enough to interact with him at multiple points through my career - from undergrad lectures, through his position as former Chair of @biologists.bsky.social’s Board of Directors, and as an author at @dev-journal.bsky.social.
Reposted by Patrick
'What happened during those reviews remains confidential, hidden behind the ethics panel’s closed doors. But the financial ties between the drugmaker and its ethics panel highlight how private-equity investors are transforming this obscure but vital corner of American health care'
How Private Equity Oversees the Ethics of Drug Research
www.nytimes.com
October 5, 2025 at 8:57 AM
'What happened during those reviews remains confidential, hidden behind the ethics panel’s closed doors. But the financial ties between the drugmaker and its ethics panel highlight how private-equity investors are transforming this obscure but vital corner of American health care'
Reposted by Patrick
'(...) the troubling question of who is actually making sense of such a cortical roadmap. Is there a tiny executive homunculus watching the visual, acoustic, somatosensory, and other sensory maps and sending out instructions to muscles in accordance with the picture of the world it is receiving?'
Wider Than the Sky: An Alternative to “Mapping” the World Onto the Brain
Challenging the topographic paradigm: The olfactory system's dynamic organization and phenomena like representational drift challenge traditional spatial mapping models, advocating for flexible, r...
onlinelibrary.wiley.com
September 30, 2025 at 6:58 AM
'(...) the troubling question of who is actually making sense of such a cortical roadmap. Is there a tiny executive homunculus watching the visual, acoustic, somatosensory, and other sensory maps and sending out instructions to muscles in accordance with the picture of the world it is receiving?'
PhD project in philosophy of science in practice. The main PI is Sara Green. Check it out!
employment.ku.dk/phd/?show=16...
employment.ku.dk/phd/?show=16...
PhD Project in Philosophy of Science: Philosophical Perspectives on Animal Models in Translational Neuroscience
employment.ku.dk
September 24, 2025 at 2:33 PM
PhD project in philosophy of science in practice. The main PI is Sara Green. Check it out!
employment.ku.dk/phd/?show=16...
employment.ku.dk/phd/?show=16...
Reposted by Patrick
A new #HOPOS paper from Tivadar Vervoort on the relations between Georg Lukács and the Frankfurt School and the French epistemologists including Michel Foucault.
“Nous Sommes Tous Néokantiens”: Foucault, Lukács, and the Critique of Social Forms
www.journals.uchicago.edu/doi/full/10....
“Nous Sommes Tous Néokantiens”: Foucault, Lukács, and the Critique of Social Forms
www.journals.uchicago.edu/doi/full/10....
September 22, 2025 at 7:01 AM
A new #HOPOS paper from Tivadar Vervoort on the relations between Georg Lukács and the Frankfurt School and the French epistemologists including Michel Foucault.
“Nous Sommes Tous Néokantiens”: Foucault, Lukács, and the Critique of Social Forms
www.journals.uchicago.edu/doi/full/10....
“Nous Sommes Tous Néokantiens”: Foucault, Lukács, and the Critique of Social Forms
www.journals.uchicago.edu/doi/full/10....
PhD and postdoc positions available in HPS at the University of Copenhagen. The project is “Human Variables in Biodiversity Assessment” with Joeri Witteveen.
employment.ku.dk/phd/?show=16...
employment.ku.dk/phd/?show=16...
PhD position in History and Philosophy of Science
employment.ku.dk
September 22, 2025 at 7:19 AM
PhD and postdoc positions available in HPS at the University of Copenhagen. The project is “Human Variables in Biodiversity Assessment” with Joeri Witteveen.
employment.ku.dk/phd/?show=16...
employment.ku.dk/phd/?show=16...
Reposted by Patrick
Two tenure track/ tenured positions--one Assist Prof & one Assoc Prof in Philosophy of Science &/or Technology at @ihpst-uoft.bsky.social
philjobs.org/job/show/29502
philjobs.org/job/show/29506
Areas include phil of social science, Native American philo, phil of race
#philsci #philtech #philjobs
philjobs.org/job/show/29502
philjobs.org/job/show/29506
Areas include phil of social science, Native American philo, phil of race
#philsci #philtech #philjobs
Assistant Professor - Philosophy of Science and/or Technology, University of Toronto
- PhilJobs:JFP
Assistant Professor - Philosophy of Science and/or Technology, University of Toronto
An international database of jobs for philosophers
philjobs.org
August 27, 2025 at 7:59 PM
Two tenure track/ tenured positions--one Assist Prof & one Assoc Prof in Philosophy of Science &/or Technology at @ihpst-uoft.bsky.social
philjobs.org/job/show/29502
philjobs.org/job/show/29506
Areas include phil of social science, Native American philo, phil of race
#philsci #philtech #philjobs
philjobs.org/job/show/29502
philjobs.org/job/show/29506
Areas include phil of social science, Native American philo, phil of race
#philsci #philtech #philjobs
Reposted by Patrick
CFA The Human Diversity Dilemma: Navigating the intersection of microbes, ethics & society
ISHPSSB Off-Year Workshop
Stellenbosch University, Cape Town, South Africa
October 1-3, 2025
Abstracts due Aug.18
Organizers @abigailnd.bsky.social & @msimang.bsky.social
#philsci #STS 🦠
More info ⤵️
ISHPSSB Off-Year Workshop
Stellenbosch University, Cape Town, South Africa
October 1-3, 2025
Abstracts due Aug.18
Organizers @abigailnd.bsky.social & @msimang.bsky.social
#philsci #STS 🦠
More info ⤵️
Home | The Human Diversity
perspectivesrace.wixsite.com
August 10, 2025 at 6:27 PM
CFA The Human Diversity Dilemma: Navigating the intersection of microbes, ethics & society
ISHPSSB Off-Year Workshop
Stellenbosch University, Cape Town, South Africa
October 1-3, 2025
Abstracts due Aug.18
Organizers @abigailnd.bsky.social & @msimang.bsky.social
#philsci #STS 🦠
More info ⤵️
ISHPSSB Off-Year Workshop
Stellenbosch University, Cape Town, South Africa
October 1-3, 2025
Abstracts due Aug.18
Organizers @abigailnd.bsky.social & @msimang.bsky.social
#philsci #STS 🦠
More info ⤵️
Reposted by Patrick
Integrating and interpreting brain maps | doi.org/10.1016/j.ti...
Imaging and recording technologies make it possible to map multiple biological features of the brain. How can these features be conceptually integrated into a coherent understanding of brain structure and function? ⤵️
Imaging and recording technologies make it possible to map multiple biological features of the brain. How can these features be conceptually integrated into a coherent understanding of brain structure and function? ⤵️
August 4, 2025 at 2:27 PM
Integrating and interpreting brain maps | doi.org/10.1016/j.ti...
Imaging and recording technologies make it possible to map multiple biological features of the brain. How can these features be conceptually integrated into a coherent understanding of brain structure and function? ⤵️
Imaging and recording technologies make it possible to map multiple biological features of the brain. How can these features be conceptually integrated into a coherent understanding of brain structure and function? ⤵️
Postdoc in Public Engagement around Personalized Medicine (Let's Get Personal)
employment.ku.dk
August 4, 2025 at 10:02 AM
Reposted by Patrick
RIP #histsci Margaret Rossiter, who coined term Matilda Effect
en.wikipedia.org/wiki/Margare...
#philsci #feministsky
en.wikipedia.org/wiki/Margare...
#philsci #feministsky
August 4, 2025 at 9:00 AM
RIP #histsci Margaret Rossiter, who coined term Matilda Effect
en.wikipedia.org/wiki/Margare...
#philsci #feministsky
en.wikipedia.org/wiki/Margare...
#philsci #feministsky
Reposted by Patrick
We already know that overselling findings and “story over substance” are a threat to scientific knowledge production.
I’m extremely worried that the massive restructuring of science funding will reproduce the same hype-dependent dynamic for research.
I’m extremely worried that the massive restructuring of science funding will reproduce the same hype-dependent dynamic for research.
August 3, 2025 at 6:12 PM
We already know that overselling findings and “story over substance” are a threat to scientific knowledge production.
I’m extremely worried that the massive restructuring of science funding will reproduce the same hype-dependent dynamic for research.
I’m extremely worried that the massive restructuring of science funding will reproduce the same hype-dependent dynamic for research.
Reposted by Patrick
Different disciplines handle the division of labor between theory and experiment. Some fields have dedicated theoreticians who hardly ever do experiments (and vice versa). Others divide it less strongly or not at all.
Why is this?
Why is this?
August 3, 2025 at 3:28 PM
Different disciplines handle the division of labor between theory and experiment. Some fields have dedicated theoreticians who hardly ever do experiments (and vice versa). Others divide it less strongly or not at all.
Why is this?
Why is this?
Reposted by Patrick
'To determine whether a screening truly works, we have to measure not survival time but mortality. Did fewer people die of cancer in the screened group? This is the outcome that really matters. Yet demonstrating such a benefit is slow, arduous work (...) you must wait for the final end point: death'
The Catch in Catching Cancer Early
New blood tests promise to detect malignancies before they’ve spread. But proving that these tests actually improve outcomes remains a stubborn challenge.
www.newyorker.com
August 3, 2025 at 6:28 AM
'To determine whether a screening truly works, we have to measure not survival time but mortality. Did fewer people die of cancer in the screened group? This is the outcome that really matters. Yet demonstrating such a benefit is slow, arduous work (...) you must wait for the final end point: death'
Reposted by Patrick
This collection of foreign bodies removed from the oesophagus was donated to the museum in 1928.
July 17, 2025 at 11:02 AM
This collection of foreign bodies removed from the oesophagus was donated to the museum in 1928.
Reposted by Patrick
Very excited to share our new work on gastruloids by the incredible Cat Triandafillou! We mapped gene expression across 26 individual gastruloids at single-cell resolution and discovered some pretty amazing patterns about how these "mini-embryos" organize themselves.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Single-cell spatial mapping reveals reproducible cell type organization and spatially-dependent gene expression in gastruloids
Gastruloids are three-dimensional stem-cell-based models that recapitulate key aspects of mammalian gastrulation, including formation of an anterior-posterior (AP) axis. However, we do not have detail...
www.biorxiv.org
July 15, 2025 at 3:43 PM
Very excited to share our new work on gastruloids by the incredible Cat Triandafillou! We mapped gene expression across 26 individual gastruloids at single-cell resolution and discovered some pretty amazing patterns about how these "mini-embryos" organize themselves.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
A Museum Contends with Its Collection of Human Remains www.newyorker.com/magazine/202...
A Medical-History Museum Contends with Its Collection of Human Remains
Supporters saw the Mütter’s preserved fetuses, skulls, and “Soap Lady” as a celebration of human difference. New management saw an ethical and a political minefield.
www.newyorker.com
June 30, 2025 at 2:24 PM
A Museum Contends with Its Collection of Human Remains www.newyorker.com/magazine/202...
Reposted by Patrick
So sorry that Helen de Cruz has died. I have never met her in person, and don't know her work well. But during Covid, she suggested that we play music together (lute and voice). We only had a few online sessions but they made me appreciate what a brilliant and warm person she is. R.I.P. #philosophy
June 22, 2025 at 8:10 AM
So sorry that Helen de Cruz has died. I have never met her in person, and don't know her work well. But during Covid, she suggested that we play music together (lute and voice). We only had a few online sessions but they made me appreciate what a brilliant and warm person she is. R.I.P. #philosophy