Author | Lightnews

Pranvera Sadiku

@pranvera.bsky.social

240 followers 310 following 3 posts

Postdoc in @walmsley-lab.bsky.social @edinuni-irr.bsky.social interested in neutrophils and metabolism.

Posts Media Videos Starter Packs

Pranvera Sadiku @pranvera.bsky.social · 4d

@walmsley-lab.bsky.social

Pranvera Sadiku @pranvera.bsky.social · 4d

Our most recent work entitled “Hypoxia induces histone clipping and H3K4me3 loss in neutrophil progenitors resulting in long-term impairment of neutrophil immunity” is now published. Well done @mas-g.bsky.social. rdcu.be/eM5MT

Hypoxia induces histone clipping and H3K4me3 loss in neutrophil progenitors resulting in long-term impairment of neutrophil immunity

Nature Immunology - Walmsley and colleagues report that systemic hypoxia induces persistent loss of histone H3K4me3 marks and epigenetic reprogramming in neutrophil progenitors, resulting in...

rdcu.be

1 8 19

Reposted by Pranvera Sadiku

bioRxiv Immunology @biorxiv-immuno.bsky.social · Jul 27

Single cell proteomic analysis defines discrete neutrophil functional states in human glioblastoma https://www.biorxiv.org/content/10.1101/2025.07.23.666094v1

2 2

Reposted by Pranvera Sadiku

Jose M. Adrover @adrover.bsky.social · Jul 17

I’m happy to share our latest work on tumour necrosis! During my time in the @megeblad.bsky.social lab, we found that tumour necrosis is not a passive phenomenon secondary to tumour growth, but an active phenomenon driven by neutrophils and NETs! Thread below: (1/13)
www.nature.com/articles/s41...

Neutrophils drive vascular occlusion, tumour necrosis and metastasis - Nature

Neutrophils actively induce tumour necrosis, driving vascular occlusion, pleomorphic necrosis and metastasis.

www.nature.com

3 25 62

Reposted by Pranvera Sadiku

Fendt Lab @fendtlab.bsky.social · Jan 1

Did you ever wonder why metastatic cancers often spread to the lungs? Amazing research from @ginevradoglioni.bsky.social! Many thanks to all collaborators, funders and patients. Wishing you all an enjoyable read and a happy new year and Ginevra a great next endeavor @salkinstitute.bsky.social

Ginevra Doglioni @ginevradoglioni.bsky.social · Jan 1

Beyond excited to share that the main work of my PhD on how aspartate signaling drives metastasis is finally out in @nature.com ✨

-> go.nature.com/4gCYtuL

A huge thank to the @fendtlab.bsky.social and all our collaborators for the terrific team work 🙏

A brief 🧵

Aspartate signalling drives lung metastasis via alternative translation - Nature

Aspartate in the tumour environment activates the N-methyl-d-aspartate receptor in cancer cells to induce cellular programmes that increase the aggressiveness of metastasis.

go.nature.com

5 10 59

Reposted by Pranvera Sadiku

Ivan Zanoni @lozanzi.bsky.social · Jan 8

#InterferonPower! Khan Tran Divanghai &co show @natimmunol.bsky.social that systemic fungal b-glucan administration potentates granulopoieis via type I IFNs (not IL1!) driving IL10-producing neutrophils that protect against lung influenza A virus infection increasing immune tolerance, not resistance

β-Glucan reprograms neutrophils to promote disease tolerance against influenza A virus - Nature Immunology

Divangahi and colleagues report that β-glucan pretreatment before influenza A virus challenge can increase survival by inducing long-term reprogramming of neutrophils, promoting disease tolerance irre...

www.nature.com

6 20

Pranvera Sadiku @pranvera.bsky.social · Jan 7

Thanks. I’d love to be added.

1 1