Priti Agarwal
@pritiagarwal.bsky.social
Assistant Professor @NCBS Interested in #Mechanobiology, #morphogenesis, # cell biology, #cytoskeleton, #microscopy and -omics. Previously at Mechanobiology Instt., NUS and TAU, Israel
https://scholar.google.com/citations?hl=en&user=J4HuJBAAAAAJ
https://scholar.google.com/citations?hl=en&user=J4HuJBAAAAAJ
Reposted by Priti Agarwal
So called microtubule organizing centers (MTOCs) are not "organizing centers". They don't control their position (network center), nor MT orientation, length and shape (network shape). The actual organizers are MTs, molecular motors and regulators of MT +ends. MTOCs nucleate MTs.
Let's rename MTOCs.
Let's rename MTOCs.
November 27, 2025 at 8:47 AM
So called microtubule organizing centers (MTOCs) are not "organizing centers". They don't control their position (network center), nor MT orientation, length and shape (network shape). The actual organizers are MTs, molecular motors and regulators of MT +ends. MTOCs nucleate MTs.
Let's rename MTOCs.
Let's rename MTOCs.
Reposted by Priti Agarwal
Reposted by Priti Agarwal
Why fundamental research is fundamental to progress, seeding major breakthroughs
Editorial @nature.com this week
And 7 basic science discoveries that changed the world
nature.com/articles/d41...
nature.com/articles/d41...
Editorial @nature.com this week
And 7 basic science discoveries that changed the world
nature.com/articles/d41...
nature.com/articles/d41...
October 29, 2025 at 12:58 PM
Why fundamental research is fundamental to progress, seeding major breakthroughs
Editorial @nature.com this week
And 7 basic science discoveries that changed the world
nature.com/articles/d41...
nature.com/articles/d41...
Editorial @nature.com this week
And 7 basic science discoveries that changed the world
nature.com/articles/d41...
nature.com/articles/d41...
Reposted by Priti Agarwal
q.e.d Science
Critical Thinking AI for constructive criticism and science evaluation
qedscience.com
October 15, 2025 at 12:22 PM
Reposted by Priti Agarwal
October 12, 2025 at 9:25 AM
The secret to our big brains? Going with the flow(Tissue fluidization)!
New preprint from the lab! We discovered a transient fluidization in the basal region of human forebrains by tracking microdroplets in cerebral organoids.This “basal fluidization”, absent in gorilla and mouse, may contribute to greater surface expansion in human forebrains
1/
doi.org/10.1101/2025...
1/
doi.org/10.1101/2025...
October 10, 2025 at 2:50 AM
The secret to our big brains? Going with the flow(Tissue fluidization)!
A stunning image!
My entry for today’s #FluorescenceFriday: a pupal #Drosophila testis with muscles expressing
🔵 lifeact &
🔴 RFP-nls
Honored & grateful to receive an honorable mention at @healthcare.nikon.com Nikon Small World 🌍🔬✨
🔗 www.nikonsmallworld.com/galleries/20...
#NikonSmallWorld #Microscopy #ScienceArt
🔵 lifeact &
🔴 RFP-nls
Honored & grateful to receive an honorable mention at @healthcare.nikon.com Nikon Small World 🌍🔬✨
🔗 www.nikonsmallworld.com/galleries/20...
#NikonSmallWorld #Microscopy #ScienceArt
October 5, 2025 at 9:42 AM
A stunning image!
Reposted by Priti Agarwal
It's online! In this series of perspectives @dev-journal.bsky.social, yours truly talks about the exciting open questions and many things to do in the field of dev bio and neuroscience #DevBio🧪 #PIsOfTomorrow journals.biologists.com/dev/article/...
Pathway to Independence: a forecast for the future of developmental biology
ABSTRACT. In 2022, Development launched its Pathway to Independence (PI) programme, aimed at supporting postdocs as they transition to their first independent position. In 2025, we welcome our third c...
journals.biologists.com
September 30, 2025 at 11:00 AM
It's online! In this series of perspectives @dev-journal.bsky.social, yours truly talks about the exciting open questions and many things to do in the field of dev bio and neuroscience #DevBio🧪 #PIsOfTomorrow journals.biologists.com/dev/article/...
🚨 New preprint!
We profile the transcriptome of the C. elegans distal tip cell: a persistent leader cell that invades basement membrane to shape the gonad.
Our dataset defines the molecular signature of invasive leader cells & uncovers new regulators of collective cell invasion.
We profile the transcriptome of the C. elegans distal tip cell: a persistent leader cell that invades basement membrane to shape the gonad.
Our dataset defines the molecular signature of invasive leader cells & uncovers new regulators of collective cell invasion.
Stage-specific transcriptomics of a leader cell reveals cell machineries driving collective invasion
Collective cell invasion underlies organ development, epithelial repair, and cancer metastasis. Leader cells remodel extracellular matrix, sense guidance cues, reorganize their cytoskeleton, and coord...
www.biorxiv.org
October 3, 2025 at 6:24 AM
🚨 New preprint!
We profile the transcriptome of the C. elegans distal tip cell: a persistent leader cell that invades basement membrane to shape the gonad.
Our dataset defines the molecular signature of invasive leader cells & uncovers new regulators of collective cell invasion.
We profile the transcriptome of the C. elegans distal tip cell: a persistent leader cell that invades basement membrane to shape the gonad.
Our dataset defines the molecular signature of invasive leader cells & uncovers new regulators of collective cell invasion.
Reposted by Priti Agarwal
If anyone ever wants to brush up on a lot of cell migration concepts don't forget we have several wonderful scientists who have given talks previously in cell migration seminars. I find it so comforting to go look at old videos, maybe someone else who will do as well!!
youtube.com/@cellmigrati...
youtube.com/@cellmigrati...
Cell Migration Seminars
Cell Migration Seminars every Tuesday at 16:00 BST.
youtube.com
September 29, 2025 at 1:48 AM
If anyone ever wants to brush up on a lot of cell migration concepts don't forget we have several wonderful scientists who have given talks previously in cell migration seminars. I find it so comforting to go look at old videos, maybe someone else who will do as well!!
youtube.com/@cellmigrati...
youtube.com/@cellmigrati...
🚨 The International Developmental Mechanics Zoom Seminar Series is back on Sept 25!
🎤 We have an exciting line-up of speakers this fall. See the image below for details
🌐 Website: sites.google.com/view/devmech...
📝 Interested in presenting? Sign up here: tinyurl.com/2munv5bv
🎤 We have an exciting line-up of speakers this fall. See the image below for details
🌐 Website: sites.google.com/view/devmech...
📝 Interested in presenting? Sign up here: tinyurl.com/2munv5bv
September 16, 2025 at 6:08 PM
🚨 The International Developmental Mechanics Zoom Seminar Series is back on Sept 25!
🎤 We have an exciting line-up of speakers this fall. See the image below for details
🌐 Website: sites.google.com/view/devmech...
📝 Interested in presenting? Sign up here: tinyurl.com/2munv5bv
🎤 We have an exciting line-up of speakers this fall. See the image below for details
🌐 Website: sites.google.com/view/devmech...
📝 Interested in presenting? Sign up here: tinyurl.com/2munv5bv
Reposted by Priti Agarwal
📢📢Hiring 2 Research Assistants & 2 Postdocs at Emory University in Atlanta to study cytoskeletal biophysics/biochemistry. Please RT.
RAs: great for recent bachelor's/master's in Physics/Bio/Chem/Biochem. Email CV and interests to [email protected].
More info: www.shekharlab.org
RAs: great for recent bachelor's/master's in Physics/Bio/Chem/Biochem. Email CV and interests to [email protected].
More info: www.shekharlab.org
August 29, 2025 at 3:50 AM
📢📢Hiring 2 Research Assistants & 2 Postdocs at Emory University in Atlanta to study cytoskeletal biophysics/biochemistry. Please RT.
RAs: great for recent bachelor's/master's in Physics/Bio/Chem/Biochem. Email CV and interests to [email protected].
More info: www.shekharlab.org
RAs: great for recent bachelor's/master's in Physics/Bio/Chem/Biochem. Email CV and interests to [email protected].
More info: www.shekharlab.org
Reposted by Priti Agarwal
A snapshot of the mechanics shaping organs: what plants and animals can teach each other.
Thank you Mabel, @MabelMathew_M and Ankita @Dash_Ankita
for putting this together.
authors.elsevier.com/a/1lamy3si8Q...
Thank you Mabel, @MabelMathew_M and Ankita @Dash_Ankita
for putting this together.
authors.elsevier.com/a/1lamy3si8Q...
authors.elsevier.com
August 12, 2025 at 7:20 AM
A snapshot of the mechanics shaping organs: what plants and animals can teach each other.
Thank you Mabel, @MabelMathew_M and Ankita @Dash_Ankita
for putting this together.
authors.elsevier.com/a/1lamy3si8Q...
Thank you Mabel, @MabelMathew_M and Ankita @Dash_Ankita
for putting this together.
authors.elsevier.com/a/1lamy3si8Q...
Reposted by Priti Agarwal
Excited to share the final version of the STRESS software paper 🎉 Do you want to measure cell or tissue stresses using deformable beads or droplets, please check this paper:
nature.com/articles/s41...
Full access: rdcu.be/ezlGj
and the preprint thread below ⬇️
x.com/CampasLab/st...
nature.com/articles/s41...
Full access: rdcu.be/ezlGj
and the preprint thread below ⬇️
x.com/CampasLab/st...
x.com
August 6, 2025 at 1:06 PM
Excited to share the final version of the STRESS software paper 🎉 Do you want to measure cell or tissue stresses using deformable beads or droplets, please check this paper:
nature.com/articles/s41...
Full access: rdcu.be/ezlGj
and the preprint thread below ⬇️
x.com/CampasLab/st...
nature.com/articles/s41...
Full access: rdcu.be/ezlGj
and the preprint thread below ⬇️
x.com/CampasLab/st...
Reposted by Priti Agarwal
Thrilled to bits to see our latest work online in Dev Cell! 🥳
We wanted to know how cells build functional organs with precision🫀🫁📏 Here we show how coupling of cell shape and organ function fine tunes the form and contractile power of the developing #zebrafish heart 1/n
tinyurl.com/cell-stretch
We wanted to know how cells build functional organs with precision🫀🫁📏 Here we show how coupling of cell shape and organ function fine tunes the form and contractile power of the developing #zebrafish heart 1/n
tinyurl.com/cell-stretch
Mechanochemical coupling of cell shape and organ function optimizes heart size and contractile efficiency in zebrafish
Andrews et al. demonstrate that multiscale feedback between mechanical and chemical
cues builds a functional heart to support zebrafish embryonic life. Cell recruitment
and organ-scale forces drive tr...
tinyurl.com
August 6, 2025 at 2:53 PM
Thrilled to bits to see our latest work online in Dev Cell! 🥳
We wanted to know how cells build functional organs with precision🫀🫁📏 Here we show how coupling of cell shape and organ function fine tunes the form and contractile power of the developing #zebrafish heart 1/n
tinyurl.com/cell-stretch
We wanted to know how cells build functional organs with precision🫀🫁📏 Here we show how coupling of cell shape and organ function fine tunes the form and contractile power of the developing #zebrafish heart 1/n
tinyurl.com/cell-stretch
Happy to share my recent clipboard article link.springer.com/article/10.1...
Thanks to @kavita-babu.bsky.social and @wormlockholmes.bsky.social
for giving me this wonderful opportunity! #germline #mechanics #cellmorphogenesis #Organ-leveldynamics
Thanks to @kavita-babu.bsky.social and @wormlockholmes.bsky.social
for giving me this wonderful opportunity! #germline #mechanics #cellmorphogenesis #Organ-leveldynamics
Caenorhabditis elegans germline flux pulls its stem-cell niche cells into shape - Journal of Biosciences
Journal of Biosciences -
link.springer.com
July 3, 2025 at 7:37 AM
Happy to share my recent clipboard article link.springer.com/article/10.1...
Thanks to @kavita-babu.bsky.social and @wormlockholmes.bsky.social
for giving me this wonderful opportunity! #germline #mechanics #cellmorphogenesis #Organ-leveldynamics
Thanks to @kavita-babu.bsky.social and @wormlockholmes.bsky.social
for giving me this wonderful opportunity! #germline #mechanics #cellmorphogenesis #Organ-leveldynamics
Interested in understanding how cells move collectively and build tissues and organs! Join the collective cell migration/dynamics starter pack by @maikbischoff.bsky.social👇 #cell migration #cellbio #devbio
What happened to #BioStarterPacks?
People still join here, but we’ve stopped sharing them!
Let’s repost them from time to time to help newcomers find their way 😊
Here’s my starter pack collective: #cellmigration
Comment if you’d like to be added—I haven’t updated it in months 😉
#cellbio #devbio
People still join here, but we’ve stopped sharing them!
Let’s repost them from time to time to help newcomers find their way 😊
Here’s my starter pack collective: #cellmigration
Comment if you’d like to be added—I haven’t updated it in months 😉
#cellbio #devbio
June 27, 2025 at 3:06 AM
Interested in understanding how cells move collectively and build tissues and organs! Join the collective cell migration/dynamics starter pack by @maikbischoff.bsky.social👇 #cell migration #cellbio #devbio
Reposted by Priti Agarwal
Interested in Developmental Mechanics??? We are organizing a mechanobiology workshop in Baeza, Spain, October 21-23, 2025. Come join us (and please help us spread the word)!!!
April 25, 2025 at 2:08 PM
Interested in Developmental Mechanics??? We are organizing a mechanobiology workshop in Baeza, Spain, October 21-23, 2025. Come join us (and please help us spread the word)!!!
Reposted by Priti Agarwal
Students (Master's/PhD), do not miss this fantastic Developmental Biology course of @sorbonne-universite.fr and @institutcurie.bsky.social - It is FREE and open to international students, however, room and board + travel are not included.
training.institut-curie.org/courses/deve...
training.institut-curie.org/courses/deve...
June 13, 2025 at 4:55 PM
Students (Master's/PhD), do not miss this fantastic Developmental Biology course of @sorbonne-universite.fr and @institutcurie.bsky.social - It is FREE and open to international students, however, room and board + travel are not included.
training.institut-curie.org/courses/deve...
training.institut-curie.org/courses/deve...
Reposted by Priti Agarwal
Shroff, N. P., Xu, P., Kim, S., Shelton, E. R., ..., Campàs, O. & Klein, O. D. (2024). Proliferation-driven mechanical compression induces signalling centre formation during mammalian organ development. Nature Cell Biology. #EpithelialMechanics www.nature.com/articles/s41...
Proliferation-driven mechanical compression induces signalling centre formation during mammalian organ development - Nature Cell Biology
Shroff and colleagues report that cell proliferation induces localized mechanical compression in the tissue, driving the formation of the main mouse tooth signalling centre via differential YAP…
www.nature.com
June 14, 2025 at 1:00 PM
Shroff, N. P., Xu, P., Kim, S., Shelton, E. R., ..., Campàs, O. & Klein, O. D. (2024). Proliferation-driven mechanical compression induces signalling centre formation during mammalian organ development. Nature Cell Biology. #EpithelialMechanics www.nature.com/articles/s41...
Reposted by Priti Agarwal
What do we see when looking at cells under the microscope? 👉Some are bigger than others, some are elongated and align with the neighbors & others seem to move. Cool, right? But wouldn't it be cooler to quantify these observations?
I'm @juliaeckert.bsky.social. Let's explore some analysis software!
I'm @juliaeckert.bsky.social. Let's explore some analysis software!
June 8, 2025 at 7:01 AM
What do we see when looking at cells under the microscope? 👉Some are bigger than others, some are elongated and align with the neighbors & others seem to move. Cool, right? But wouldn't it be cooler to quantify these observations?
I'm @juliaeckert.bsky.social. Let's explore some analysis software!
I'm @juliaeckert.bsky.social. Let's explore some analysis software!
Reposted by Priti Agarwal
🔬💡A serendipitous discovery while troubleshooting an imaging issue led Yamini @yamini.bsky.social down a project studying mechanically induced morphogenesis in Hydra
Check out this new 'behind the paper story' ⬇️
Check out this new 'behind the paper story' ⬇️
Thank you for this opportunity @the-node.bsky.social to let me share the behind the story of my postdoc article from the @rouxlab.bsky.social here’s to squishing jellies!!
Squishing jellies!! - the Node
Behind the paper: “Topology changes of Hydra define actin orientation defects as organizers of morphogenesis”
thenode.biologists.com
June 5, 2025 at 7:43 AM
🔬💡A serendipitous discovery while troubleshooting an imaging issue led Yamini @yamini.bsky.social down a project studying mechanically induced morphogenesis in Hydra
Check out this new 'behind the paper story' ⬇️
Check out this new 'behind the paper story' ⬇️
Reposted by Priti Agarwal
*Paid internship opportunity*
@biologists.bsky.social is looking for a 3-month intern this summer to work across the Node, @prelights.bsky.social and
@focalplane.bsky.social
If you're interested in #SciCommm & #publishing, and have the right to work in the UK, apply by 5 June 👇
@biologists.bsky.social is looking for a 3-month intern this summer to work across the Node, @prelights.bsky.social and
@focalplane.bsky.social
If you're interested in #SciCommm & #publishing, and have the right to work in the UK, apply by 5 June 👇
Community site paid internship - the Node
The Company of Biologists currently has an opportunity for a paid three-month internship to work on our community sites – the Node, preLights and FocalPlane. This is a great opportunity to gain experi...
thenode.biologists.com
May 21, 2025 at 10:38 AM
*Paid internship opportunity*
@biologists.bsky.social is looking for a 3-month intern this summer to work across the Node, @prelights.bsky.social and
@focalplane.bsky.social
If you're interested in #SciCommm & #publishing, and have the right to work in the UK, apply by 5 June 👇
@biologists.bsky.social is looking for a 3-month intern this summer to work across the Node, @prelights.bsky.social and
@focalplane.bsky.social
If you're interested in #SciCommm & #publishing, and have the right to work in the UK, apply by 5 June 👇
Story of resilience!
This is a science 🧪 story about Mount St Helens, and gophers, and how small positive actions can, in time, make a big difference. I thought a few of you might need to hear it this week. (1/x) 🧵
May 18, 2025 at 3:44 PM
Story of resilience!
Reposted by Priti Agarwal
A most inspiring thread!
This is a science 🧪 story about Mount St Helens, and gophers, and how small positive actions can, in time, make a big difference. I thought a few of you might need to hear it this week. (1/x) 🧵
May 18, 2025 at 1:50 PM
A most inspiring thread!