PSanchoLab
@psancholab.bsky.social
710 followers
380 following
24 posts
Working on cancer metabolism focused on pancreatic cancer and cancer stem cells. Interested in drug repurposing for cancer treatment
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PSanchoLab
@psancholab.bsky.social
· Jul 4
PSanchoLab
@psancholab.bsky.social
· Jul 4
PSanchoLab
@psancholab.bsky.social
· Jul 4
PPAR-δ Orchestrates a Pro-metastatic Metabolic Response to Microenvironmental Cues in Pancreatic Cancer
Abstract. The pronounced desmoplastic response in pancreatic ductal adenocarcinoma (PDAC) contributes to the development of a microenvironment depleted of oxygen and nutrients. To survive in this host...
aacrjournals.org
Reposted by PSanchoLab
Reposted by PSanchoLab
Reposted by PSanchoLab
Reposted by PSanchoLab
Reposted by PSanchoLab
Fernando Calvo
@calvolab.bsky.social
· Apr 25
Proteostasis control via HSP90α sustains YAP activity to drive aggressive behaviours in cancer-associated fibroblasts
Cancers adapt proteostasis to cope with the burden of misfolded proteins, stabilize key signalling nodes and sustain their malignant behaviour. Tumour stroma is subjected to similar stresses, but how ...
doi.org
Reposted by PSanchoLab
PSanchoLab
@psancholab.bsky.social
· Apr 25
Reposted by PSanchoLab
Reposted by PSanchoLab
PSanchoLab
@psancholab.bsky.social
· Feb 11
Reposted by PSanchoLab
Reposted by PSanchoLab
Reposted by PSanchoLab