Radcliffe Department of Medicine
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rdm.ox.ac.uk
Radcliffe Department of Medicine
@rdm.ox.ac.uk
We are a University of Oxford department specialising in cardiovascular medicine, metabolism, haematology and immunology. www.rdm.ox.ac.uk
Congratulations to the 2025 RDM Graduate Prize winner - Lauren Murphy πŸŽ‰

The annual RDM Graduate Prize is awarded to current or recently graduated students of RDM supervisors for exceptional achievement in their research.

Read more about Lauren's work πŸ‘‡

shorturl.at/QWaty

@imm.ox.ac.uk
2025 RDM Graduate Prize winner
Congratulations to the 2025 RDM Graduate Prize Winner; Lauren Murphy.
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January 15, 2026 at 12:16 PM
Researchers have discovered that previous episodes of hypoglycaemia alter how cells within the pancreas communicate, reducing the release of glucagon - the hormone responsible for raising blood glucose levels when they fall dangerously low.

Read more πŸ‘‡

shorturl.at/AVOpI

@medsci.ox.ac.uk
Why the body stops protecting itself against low blood sugar
New RDM research reveals how prior hypoglycaemia weakens a key hormonal defence.
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January 13, 2026 at 4:51 PM
Reposted by Radcliffe Department of Medicine
Back in December, we shared that the #MRCWIMM #Sustainability Team received an award at the #LEAF Oxford Forum 🌱 πŸ§ͺ

The full story is now live on our website, with more on the people and work behind this recognition.

Read more πŸ‘‡
@medsci.ox.ac.uk @ox.ac.uk #ResearchCulture #WIMMHighlights
MRC WIMM Sustainability Team recognised at LEAF Oxford Forum
Congratulations to the Sustainability Committee and Working Group, who received an award for β€˜Community and Culture’ at the LEAF Oxford Forum 2025.
www.imm.ox.ac.uk
January 13, 2026 at 1:18 PM
Researchers have found that the most common liver disease follows a strong day-night pattern, and the metabolic changes that drive the disease are most pronounced overnight, when the body is least able to process sugar and fat.

Read more πŸ‘‡

shorturl.at/SvCEe

@oxfordbrc.bsky.social
Night-time changes in metabolism may be driving common liver disease
Researchers at the University of Oxford have discovered that the most common liver disease follows a strong day-night pattern, and the metabolic changes that drive the disease are most pronounced over...
shorturl.at
January 13, 2026 at 8:39 AM
Researchers from the Acute Multidisciplinary Imaging and Interventional Centre (AMIIC) in RDM are leading a new partnership to strengthen international collaboration in advanced medical imaging, with a focus on improving how heart disease is studied and diagnosed.

Read more πŸ‘‡

shorturl.at/zQxQy
Scientists in the UK and Germany partner to advance heart imaging research
Researchers from the Acute Multidisciplinary Imaging and Interventional Centre (AMIIC) in RDM’s Division of Cardiovascular Medicine are leading a new partnership to strengthen international collaborat...
shorturl.at
January 8, 2026 at 1:39 PM
Reposted by Radcliffe Department of Medicine
NEWS: Oxford recruits first participant in Europe for heart inflammation treatment study

The patient has been recruited by the Acute Multidisciplinary Imaging and Interventional Centre (AMIIC) team, which is a state-of-the art facility in @rdm.ox.ac.uk
Oxford recruits first participant in Europe for heart inflammation treatment study
FORTIFY is an international clinical trial to test a potential treatment for people with coronary inflammation. The first patient in Europe has been recruited by the team at the Acute Multidisciplinary Imaging and Interventional Centre (AMIIC). AMIIC is a state-of-the art facility in the Radcliffe Department of Medicine linking interventional, non-invasive imaging and artificial intelligence/big data capabilities.
www.medsci.ox.ac.uk
January 8, 2026 at 1:00 PM
Reposted by Radcliffe Department of Medicine
#WIMMReads
πŸ§ͺ A new article on cancer inequalities shows why inclusive research is essential to beat cancer for everyone.

Written by Cancer Research UK experts including #MRCWIMM Director KJ Patel.

#CancerResearch #CancerInequalities @cancerresearchuk.org @rdm.ox.ac.uk @medsci.ox.ac.uk @ox.ac.uk πŸ§¬πŸ”¬
Cancer inequalities: Empowering inclusive cancer research
Experts from Cancer Research UK share how through world-class research, we can better understand and tackle the impacts of cancer inequalities
www.openaccessgovernment.org
January 8, 2026 at 10:03 AM
Reposted by Radcliffe Department of Medicine
#WIMMReads: A new #review in Nature Reviews Immunology by Hal Drakesmith and Joe N Frost explores how #iron shapes immune responses in infection inflammation and cancer.
Read more πŸ‘‡

#Immunology #Immunology #IronMetabolism #Infection
@rdm.ox.ac.uk @drakesmith-lab.bsky.social @medsci.ox.ac.uk
Iron and the immune system - Nature Reviews Immunology
Iron is crucial for cellular metabolism, but its availability varies greatly within and between individuals and populations. This Review highlights how iron regulates innate and adaptive cellular and ...
www.nature.com
December 18, 2025 at 9:28 AM
Almost every species on Earth fundamentally needs iron. This feature on the work led by @drakesmith-lab.bsky.social from @imm.ox.ac.uk reveals more about iron's complex role in shaping human health. www.ox.ac.uk/pulse/health...
Tackling iron deficiency
More than 1.2 billion people worldwide are so iron-deficient that they develop iron-deficiency anaemia. The consequences include fatigue, dizziness, hair loss, greater risk of pregnancy complications,...
www.ox.ac.uk
December 16, 2025 at 9:37 AM
Reposted by Radcliffe Department of Medicine
Reposted by Radcliffe Department of Medicine
Huge congratulations to Holly Russell who has been awarded a fellowship from the Lee Placito Medical Fund.

@rdm.ox.ac.uk @medsci.ox.ac.uk @ox.ac.uk

www.imm.ox.ac.uk/news/holly-r...
Holly Russell receives Lee Placito Research Fellowship
Congratulations to Holly Russell who has been awarded a fellowship from the Lee Placito Medical Fund.
www.imm.ox.ac.uk
December 9, 2025 at 1:57 PM
The @meassociation.org.uk is taking part in Big Give's #ChristmasChallenge this week to raise money to support a case-control study led by some of our researchers. The study will use MRI and Near-Infrared Spectroscopy to uncover what goes wrong in the muscles during Post-Exertional Malaise.
We’re taking part in Big Give’s #ChristmasChallenge from 2–9 December; every donation you make to the ME Association will be DOUBLED by Big Give!

Donate here: https://meassociation.org.uk/BigGive2025

#MECFS #MyalgicEncephalomyelitis #LongCovid #BigGive2025 #WhenRestIsntEnough #DoubleYourDonation
December 2, 2025 at 3:50 PM
Reposted by Radcliffe Department of Medicine
"It's beginning to look a lot like Gutmas!"

Congratulations to @vywien-lai.bsky.social on winning the MRF/MRC 2025 Festive Science Image Competition with these striking cross sections of gut tissue at different developmental stages πŸ§ͺπŸŽ„

@medresfdn.bsky.social @ukri.org @rdm.ox.ac.uk

Learn more πŸ‘‡
It's beginning to look a lot like Gutmas!
Congratulations to Vy Wien Lai, whose image was chosen for 1st place in the MRC/MRF 2025 Festive Science Image Competition.
www.imm.ox.ac.uk
December 1, 2025 at 9:56 AM
Reposted by Radcliffe Department of Medicine
Don’t miss out on this opportunity- come and join us at the Oxford Organoid Hub working under the MRC-BHF REACT programme! If you love in vitro 3D models, the ❀️ and regenerative therapies, this is for you - apply by 18 Dec @oxforddpag.bsky.social @idrm.ox.ac.uk @rdm.ox.ac.uk
Some good news, myself and @simoesfilipa.bsky.social are advertising for a post-doctoral researcher to join us at the Oxford Organoid hub: tinyurl.com/OOHJob

Come and join us to develop novel human organoid systems as part of the MRC/BHF CRE in advanced cardiac therapies.
November 30, 2025 at 11:02 PM
Reposted by Radcliffe Department of Medicine
How much do you know about what’s going on in your gut? 🦠

That’s the question that a group of scientists, led by @anna-aulicino.bsky.social from the Simmons Group, asked attendees at β€˜TECHWORKS’ - one of #IFOxford’s family zones this year.

Learn more πŸ‘‡

@rdm.ox.ac.uk | @medsci.ox.ac.uk
Battle in the Gut at IF Oxford 2025
In October 2025, researchers from the MRC Translational Immune Discovery Unit led activities on researching gut bacteria at Oxford Science + Ideas Festival.
www.imm.ox.ac.uk
November 25, 2025 at 1:59 PM
Reposted by Radcliffe Department of Medicine
#WIMMReads: Researchers from the MRC Molecular Haematology Unit and the MRC WIMM Centre for Computational Biology review how #DNA sequence shapes the complex regulatory layers inside our cells.
Read more πŸ‘‡

#Genomics
#3DGenome
#ComputationalBiology
@rdm.ox.ac.uk @medsci.ox.ac.uk
The emerging sequence grammar of 3D genome organisation - Human Genetics
The multiplexed layers of regulatory processes and mechanisms within a cell are, to a degree, encoded in our genome. Unravelling the relationship between DNA sequence and molecular processes is crucia...
doi.org
November 20, 2025 at 9:38 AM
We are delighted to welcome @profjdchalmers.bsky.social to @rdm.ox.ac.uk as the Rhodes Professor of Experimental Therapeutics and Clinical Pharmacology. James conducts clinical trials and translational research to understand airway disease and develop new therapies. www.rdm.ox.ac.uk/news/profess...
Professor James Chalmers to join the Radcliffe Department of Medicine
We are delighted to announce that Professor James Chalmers has been recruited to the statutory Rhodes Professorship of Experimental Therapeutics and Clinical Pharmacology at the University of Oxford. ...
www.rdm.ox.ac.uk
November 19, 2025 at 12:00 PM
Reposted by Radcliffe Department of Medicine
NEW: Researchers in the Vyas Group used TARGET-seq+ to uncover how drug resistance develops in new treatment for acute myeloid leukaemia - these findings could help identify patients likely to relapse & find ways to prevent or treat relapse πŸ§ͺ

Learn more πŸ‘‡

@rdm.ox.ac.uk @oxfordbrc.bsky.social
Study reveals how drug resistance develops early in targeted AML therapy
A new study led by researchers at the MRC Molecular Haematology Unit has shown that resistance to a targeted treatment for acute myeloid leukaemia (AML) can develop much earlier than expected.
www.imm.ox.ac.uk
November 17, 2025 at 1:26 PM
Reposted by Radcliffe Department of Medicine
#WIMMReads: New @nature.com study, led by the Simmons & Antanaviciute Groups, used advanced single-cell and spatial analysis techniques to map the cells that drive #Crohn's fistulas - paving the way for targeted treatments πŸ§ͺ

Learn more πŸ‘‡

@rdm.ox.ac.uk @medsci.ox.ac.uk @ox.ac.uk
Oxford scientists map the cells that drive Crohn’s disease fistulas
Researchers at the MRC Translational Immune Discovery Unit have identified how rare populations of abnormal cells drive the formation and persistence of fistulas - painful, tunnel-like tracts that dev...
www.imm.ox.ac.uk
November 13, 2025 at 9:34 AM
Great to hear @jojdavies.bsky.social on @bbc5live.bsky.social last week, talking about how his team have been able to see the most detailed view yet of DNA inside a cell.

This allows them to find where things go wrong in disease.

Listen again (from 26 mins) πŸ‘‡
www.bbc.co.uk/sounds/play/...
5 Live Drive - 05/11/2025 - BBC Sounds
A round-up of the day's top news and sport with Clare McDonnell and Chris Warburton.
www.bbc.co.uk
November 11, 2025 at 11:30 AM
Professor Ellie Tzima has been awarded a highly competitive ERC Synergy Grant to investigate the enigmatic neurovascular interface of peripheral nerves – a critical but poorly understood junction between the nervous and vascular systems.

@erc.europa.eu

www.rdm.ox.ac.uk/news/profess...
Professor Ellie Tzima receives €10m to investigate the neurovascular interface of peripheral nerves
www.rdm.ox.ac.uk
November 7, 2025 at 11:18 AM
Scientists have the most detailed view yet of how DNA folds and functions inside living cells!

The breakthrough helps us understand how genetic differences lead to disease and opens up fresh routes for drug discovery πŸ‘‡

shorturl.at/nQjsx

@jojdavies.bsky.social @imm.ox.ac.uk @medsci.ox.ac.uk
Oxford scientists capture genome’s structure in unprecedented detail
RDM scientists have achieved the most detailed view yet of how DNA folds and functions inside living cells, revealing the physical structures that control when and how genes are switched on.
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November 6, 2025 at 11:18 AM
Reposted by Radcliffe Department of Medicine
We are thrilled to share that Dr Abdullah Khan has received a Wellcome Career Development Award for his research on age-related immune dysfunction.

Congratulations, Abs! πŸ‘

www.imm.ox.ac.uk/news/abs-kha...
@rdm.ox.ac.uk @medsci.ox.ac.uk @ox.ac.uk @abattacks.bsky.social
Abdullah Khan receives Wellcome Career Development Award
Congratulations are in order for Dr Abdullah (Abs) Khan, who has been awarded a Wellcome Career Development Award for his research on age-related immune dysfunction using human model systems.
www.imm.ox.ac.uk
November 4, 2025 at 10:11 AM
Congratulations to DPhil student Waleed Seddiq who has been awarded an UKEV MOVE Fellowship to advance heart disease research.

Read more πŸ‘‡

shorturl.at/u1OfV
DPhil student awarded UKEV MOVE Fellowship to advance heart disease research
Congratulations to RDM DPhil student Waleed Seddiq, who has been awarded a MOVE Fellowship from the UK Society for Extracellular Vesicles (UKEV).
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October 20, 2025 at 2:45 PM