Filipa Simões
@simoesfilipa.bsky.social
3.1K followers 710 following 110 posts
Development and Regeneration of the Heart | Cardio-Immuno Genomics | Group Leader University of Oxford IDRM-DPAG | playing with zebrafish & cardiac organoids | academic mama of 2 children & 1 dog | curiosity led
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simoesfilipa.bsky.social
Just published! Our Review on how immune cells masterfully orchestrate heart development and regeneration. Beyond fighting pathogens, they're actually building & repairing your heart! Learn how cutting-edge technologies are driving therapeutic opportunities here www.sciencedirect.com/science/arti...
Immune-mediated cardiac development and regeneration
The complex interplay between the immune and cardiovascular systems during development, homeostasis and regeneration represents a rapidly evolving fie…
www.sciencedirect.com
Reposted by Filipa Simões
tuuliel.bsky.social
This is a landmark paper and resource describing circulating proteome variation in human diseases. Congrats to many colleagues in 🇸🇪 @proteinatlas.bsky.social @scilifelab.se !
Reposted by Filipa Simões
drgillesv.bsky.social
Only a few days left to apply to join the lab, come have fun with lasers and fish to answer some cool questions along the gut-brain axis. Denmark is also a lovely country to live in!
drgillesv.bsky.social
We are recruiting a postdoc to join our team and study neuroinflammation along the gut-brain axis. Please share it with anyone who may be interested, and do not hesitate to reach out if you have questions.
international.au.dk/about/profil...
Postdoc position in Neuroinflammation - Vacancy at Aarhus University
Vacancy at Department of Molecular Biology and Genetics - Neurobiology, Aarhus University
international.au.dk
Reposted by Filipa Simões
Reposted by Filipa Simões
richardsever.bsky.social
Super-impressive - I’ve seen this peer review training in action. Something other institutions should replicate prereview.org/clubs/hhmi-t...
Reposted by Filipa Simões
profannawatts.bsky.social
Lol the Nobels can't even acknowledge women's contribution to discovery. But sure let's acknowledge The Machines.
Headline from an article in Nature this week that states "Prizes must recognize machine contributions to discovery. The future of science will be written by humans and machines together. Awards should reflect that reality."
Reposted by Filipa Simões
Reposted by Filipa Simões
crick.ac.uk
We're now recruiting early career group leaders at the Crick to lead ambitious research programmes and explore bold scientific questions.

Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research.

Apply now ➡️ www.crick.ac.uk/careers-stud...
Reposted by Filipa Simões
ebisuyamiki.bsky.social
New preprint from the lab! We discovered a transient fluidization in the basal region of human forebrains by tracking microdroplets in cerebral organoids.This “basal fluidization”, absent in gorilla and mouse, may contribute to greater surface expansion in human forebrains
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doi.org/10.1101/2025...
Reposted by Filipa Simões
jowolff.bsky.social
This was not a sample of academics.
yougov.co.uk
How many browsing tabs do you typically have open?*

1: 6%
2-5: 54%
6-10: 14%
11-20: 8%
21-30: 2%
More than 30: 3%

*across all windows, on desktop/laptop

yougov.co.uk/topics/techn...
Reposted by Filipa Simões
mrsantos.bsky.social
John Gurdon was a true giant:
- founder of cell reprogramming;
- founder of molecular embryology;
- unabashed advocate for basic research;
- advisor to numerous successful trainees/PIs;
- gentle human that touched so many.
In dark times with science under attack, let his vision be a guiding light.
katherine-brown.bsky.social
Very saddened to hear of John Gurdon’s passing. I’ve been lucky enough to interact with him at multiple points through my career - from undergrad lectures, through his position as former Chair of @biologists.bsky.social’s Board of Directors, and as an author at @dev-journal.bsky.social.
Nobel Laureate Professor Sir John Gurdon dies aged 92
It is with great sadness that the University shares the news of the death of Professor Sir John Gurdon, founder of the Gurdon Institute.
www.cam.ac.uk
Reposted by Filipa Simões
labrawlins.bsky.social
Saddened to learn of the death of John Gurdon today. He was the supreme scientist. And truly inspirational lecturer and speaker. The Gurdon Institute @gurdoninstitute.bsky.social has been a wonderful place to run a lab - and he will be truly missed.

www.gurdon.cam.ac.uk/nobel-laurea...
Nobel Laureate Professor Sir John Gurdon Dies Aged 92 – Gurdon Institute
www.gurdon.cam.ac.uk
Reposted by Filipa Simões
sumrubayin.bsky.social
John Gurdon's research inspired me in my own scientific pursuits as a stem cell biologist. Starting my lab at
@gurdoninstitute.bsky.social was therefore particularly exciting. Seeing him around daily only underscored his admirable dedication to science and research. RIP John.
tinyurl.com/nha6z25h
Reposted by Filipa Simões
michaelhendricks.bsky.social
"The work I was involved in had no obvious therapeutic benefit. It was purely of scientific interest. I hope the country will continue to support basic research even though it may have no obvious practical value."
- John Gurdon
katherine-brown.bsky.social
Very saddened to hear of John Gurdon’s passing. I’ve been lucky enough to interact with him at multiple points through my career - from undergrad lectures, through his position as former Chair of @biologists.bsky.social’s Board of Directors, and as an author at @dev-journal.bsky.social.
Nobel Laureate Professor Sir John Gurdon dies aged 92
It is with great sadness that the University shares the news of the death of Professor Sir John Gurdon, founder of the Gurdon Institute.
www.cam.ac.uk
Reposted by Filipa Simões
nsota.bsky.social
With grateful thanks for the life of the Nobel scientist, Sir John Gurdon: a man of immeasurable kindness & humility as well as a visionary biologist.

www.magd.cam.ac.uk/news/profess...
Reposted by Filipa Simões
katherine-brown.bsky.social
It’s no underestimate to say that he founded a whole field of biology - reprogramming - and his influence on the #devbio field and community has been enormous. He’ll be sorely missed, but his legacy will live on.
simoesfilipa.bsky.social
A huge loss for our community, truly sad news…
Reposted by Filipa Simões
cellysally.bsky.social
An inspiration to so many of us. I can say with no hesitation that reading John Gurdon's papers as an undergraduate changed my life. I was reprogrammed from a slightly bored biochemistry student into a person with a life-long love of developmental biology. I have much to thank him for.
Reposted by Filipa Simões
jamesbriscoe.bsky.social
Very sad news, John Gurdon has died.

A developmental biologist's developmental biologist, Nobel prize winner

His work is the foundation of much of today's dev & stem cell bio.

An inspiration to many, including me. Always asking questions & wanting the answers

www.magd.cam.ac.uk/news/profess...
Professor Sir John Gurdon FRS (1933-2025) | Magdalene College
Magdalene College is deeply saddened to announce the death of Professor Sir John Gurdon FRS, who served as Master of the College from 1995 to 2002.
www.magd.cam.ac.uk
Reposted by Filipa Simões
professor-dave.bsky.social
A remarkable transformation in @rsc.org prizes.
30% of prizes recognise teams rather than individuals (up from 5%).
36% of prize-winners are early-career (up from 4%)
38% of prize winners are women (up from 25%)
Twice as many prizes for work outside universities.
www.rsc.org/policy-and-c...
Reshaping recognition: evolving how we celebrate excellence
A multi-year journey to transform our prizes
www.rsc.org
Reposted by Filipa Simões
akanksha-jain.bsky.social
🧠 Join us @uzh-ch.bsky.social ! We are a new lab looking for PhDs, Postdocs & Master’s students interested in studying how human neural systems emerge & go awry using brain organoids, light-sheet imaging & genomics. 🚀 Deadline for LSZGS 1st Nov! www.lifescience-graduateschool.uzh.ch/en.html.
Reposted by Filipa Simões
mitisbio.bsky.social
Our calcium paper is out in PLOS Biology!
Check it out! #Calcium #Embryo #Development
plosbiology.org
During #development, distal visceral #endoderm (DVE) cells migrate to shape A-P axis specification. @m-stower.bsky.social @srinivas-lab.bsky.social &co reveal the role of Ca2+ dynamics in this, showing that inhibition of #calcium transients causes DVE arrest @plosbiology.org 🧪 plos.io/4nHWxF4
Epiblast Ca2+ waves propagate from the apical to basal domain. The images show selected time points from movies of E5.5 GCaMP6f embryos imaged using a ZEISS lattice light-sheet 7 microscope. Top row: An example of an epiblast wave involving a large proportion of the tissue captured by imaging a volume of the embryo at 20-s intervals. A total of 9/16 embryos showed at least one epiblast Ca2+ wave. Bottom row: Faster imaging at 5-s interval revealed that the Ca2+ wave in the epiblast can be preceded by a transient in a neighboring VE cell—this was observed in 5/19 events from 9 embryos (white arrowheads).
Reposted by Filipa Simões
dev-journal.bsky.social
Issue 18 is complete!

On the cover: Clones on Drosophila retina with activated Mbt kinase (pink), expanding Sdk protein (yellow) from tri- to bi-cellular adheren junctions & distorting the ommatidial lattice (cyan).

See Research Article by Gandhi et al.

journals.biologists.com/dev/article/...