Lightnews — Scholar-powered news

SMT Evidence @smtevidence.com · 5h

H/T @hildabast.bsky.social for the share in her excellent newsletter

SMT Evidence @smtevidence.com · 5h

“The most important thing about #AI isn't its technical capabilities or limitations. The most important thing is the investor story and the ensuing mania that has teed up an economical catastrophe that will harm hundreds of millions or even billions of people.”

pluralistic.net/2025/09/27/e...

Pluralistic: The real (economic) AI apocalypse is nigh (27 Sep 2025) – Pluralistic: Daily links from Cory Doctorow

pluralistic.net

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SMT Evidence @smtevidence.com · 1d

A microsimulation model to estimate the impact of care disruption during the COVID-19 pandemic on breast cancer mortality using an administrative database.

www.jclinepi.com/article/S089...

Via @jclinepi.bsky.social

A microsimulation model based on healthcare pathways to estimate the impact of COVID-19 pandemic–induced delays on breast cancer mortality

This study aimed to develop a microsimulation model to estimate the impact of a care disruption during the COVID-19 pandemic on breast cancer mortality using an administrative database.

www.jclinepi.com

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ACOG @acog.org · 17d

ACOG reaffirms that acetaminophen is safe for managing pain and fever during pregnancy. No reputable studies support suggestions like those in HHS’s recent announcement linking acetaminophen use in pregnancy to autism; in fact, high-quality studies show no such risk. https://bit.ly/47Wxc59

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NIHR Innovation Observatory @nihr-io.bsky.social · Sep 3

🚨Emerging Point-of-Care Testing in Genomics

Exploring the development pipeline of genomic POCTs designed to identify variations in the genome & epigenome, supporting diagnosis, prognosis & treatment decisions across clinical areas👉 ow.ly/UB2R50WQcvo @newcastleuni.bsky.social @nihr.bsky.social

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SMT Evidence @smtevidence.com · 26d

The contribution of conference abstracts in #systematicreviews - "Their inclusion changed the effect estimate in 55.6% and imprecision in 16% of cases when using MIDs. In a few instances, CAs also influenced RoB and inconsistency assessments."

www.jclinepi.com/article/S089...

@jclinepi.bsky.social

Including conference abstracts rarely changed systematic review conclusions: a case study from a living network meta-analysis of COVID-19 treatments

Including conference abstracts (CAs) in systematic reviews (SRs) helps reduce publication bias but raises concerns about reporting quality and reliability. While discrepancies with full publications a...

www.jclinepi.com

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Swift Science Writing @swiftsciencewriting.co.uk · Sep 4

Most Americans still don’t know that #alcohol can cause #cancer — and the alcohol industry and Trump are working hard to make sure it stays that way by discrediting and burying a new report that offers new evidence of the link between drinking alcohol and dying www.vox.com/health/46008... @vox.com

Exclusive: RFK Jr. and the White House buried a major study on alcohol and cancer. Here’s what it shows.

Kennedy wants to “Make America Healthy Again” — but doesn’t want you to see a report that could do just that.

www.vox.com

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Science Magazine @science.org · Sep 2

In a new #ScienceExpertVoices article, Seth Berkley unravels the arc of vaccine progress. https://scim.ag/3VrCDBx

Quote by Seth Berkley on a black background, stating: "…one of humanity's most dramatic successes has been the application of science to understand and then decisively intervene to improve...harrowing conditions."

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The Conversation U.S. @us.theconversation.com · Aug 20

Most air cleaning devices have not been tested on people, and little is known about their potential harms. Professors of medicine and public health explain:

Most air cleaning devices have not been tested on people − and little is known about their potential harms, new study finds

Manufacturers often make bold claims about how well these technologies work. Better testing would allow consumers and institutions to pick the most effective ones.

buff.ly

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SMT Evidence @smtevidence.com · Aug 20

New #research that could help clinical trials avoid early termination.

Identifying predictors of early trial termination: a meta-epidemiological study utilising elements of the research ethics committee evaluation.

www.jclinepi.com/article/S089...

Via @jclinepi.bsky.social

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SMT Evidence @smtevidence.com · Aug 6

A really thought-provoking article from @elife.bsky.social about manuscript publication, peer review and who acts as the gatekeepers of publishing: “why are indexers unable to see that peer review can be more than a thumbs up or a thumbs down?” sfdora.org/2025/07/30/s... H/T @hildabast.bsky.social

Why are indexers unable to see that peer review can be more than a thumbs up or a thumbs down? | DORA

Journals and peer review are unlikely to change for the better if the companies that operate scientific indexes and citation databases continue to stifle innovation. At eLife we believe that the conte...

sfdora.org

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SMT Evidence @smtevidence.com · Jul 30

Does this infographic possibly miss out the fact that Americans also tend to drive much larger SUVs, which increases the likelihood of pedestrian fatalities quite substantially, especially for children? www.lshtm.ac.uk/newsevents/n...

Being hit by an SUV increases the likelihood of death or serious injury | LSHTM

The likelihood of a pedestrian or cyclist being fatally injured is 44% higher if they are hit by a sports utility vehicle (SUV) or light truck vehicle (LTV) compared with smaller passenger cars, new

www.lshtm.ac.uk

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Nature Portfolio @natureportfolio.nature.com · Jul 25

A Review in Nature Reviews Endocrinology assesses the role of ultra-processed foods in obesity, examining the epidemiological evidence, biological mechanisms and implications for policymakers. go.nature.com/44zGHoO 🍎📃 #medsky 🧪

This is figure 2, which shows physiological pathways underlying the association between ultra-processed dietary patterns and obesity.

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New Scientist @newscientist.com · Jul 20

In human beings, egg cells need to survive for about five decades, much longer than most other cell types – and they may achieve this unusually long lifespan by slowing down their natural cell processes.

How human eggs stay fresh for decades

In human beings, egg cells need to survive for about five decades, much longer than most other cell types – and they may achieve this unusually long lifespan by slowing down their natural cell processes

www.newscientist.com

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ZB MED - Informationszentrum Lebenswissenschaften @zbmed.bsky.social · Jun 12

#SupportOLSPub - every vote counts
The first giant steps have been taken, the OLSPub application has been submitted. For all those who, as researchers, information specialists or simply as people, would like to position themselves, everyone can leave a signature here.
blog.zbmed.de/olspub-support

OLSPub support – ZB MED-Blog

Support for the project OLSPub - Open Life Science Publications Database as individuals.

blog.zbmed.de

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Eric Topol @erictopol.bsky.social · Jun 4

The MAHA report critique, by @hiltzikm.bsky.social
www.latimes.com/business/sto...
And the Trojan horse, by @drjengunter.bsky.social
vajenda.substack.com/p/hijacking-...

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Eric Topol @erictopol.bsky.social · Jun 1

The remarkable benefit of exercise was just extended to improved survival after cancer in a randomized trial
@nejm.org
nejm.org/doi/full/10....

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SMT Evidence @smtevidence.com · May 29

In the wake of several countries legalising #marijuana, questions remain about the drug's long-term #health effects. A new study has found that people who smoke weed or use edibles do worse on measures of vascular health that predict cardiovascular risk.

jamanetwork.com/journals/jam...

@jama.com

Endothelial Dysfunction and Chronic Cannabis Use

This cross-sectional study aims to determine whether cannabis use is associated with vascular endothelial function.

jamanetwork.com

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SMT Evidence @smtevidence.com · May 23

A scoping review of carbon emissions associated with clinical trials finds that several trial activities, including travel and meetings, trial facilities, and sample & lab activities, are consistently carbon heavy.

www.jclinepi.com/article/S089...

@jclinepi.bsky.social

#scopingreview #openaccess

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SMT Evidence @smtevidence.com · May 18

Brand new SPIRIT and CONSORT #reporting #guidelines are out now!

🎯 CONSORT 2025 for reporting RCTs now has a 30-item checklist

🎯 SPIRIT 2025 for reporting trial protocols now has a 34-item checklist

www.jclinepi.com/article/S089...

@jclinepi.bsky.social

#SPIRIT #CONSORT #RCTs #protocols

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Journal of Clinical Epidemiology @jclinepi.bsky.social · May 17

What makes a good guideline? – A systematic review and analysis of 120 clinical practice guidelines using the AGREE II tool - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

What makes a good guideline? – A systematic review and analysis of 120 clinical practice guidelines using the AGREE II tool

Clinical practice guidelines (CPGs) translate evidence into actionable recommendations to enhance care quality, improve clinical outcomes, reduce treatment variations, and make healthcare delivery mor...

www.jclinepi.com

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SMT Evidence @smtevidence.com · May 11

A new reporting guideline has just been published for the involvement of patients and caregivers in identifying and designing healthcare interventions: the IDEAS framework www.jclinepi.com/article/S089... HT @jclinepi.bsky.social #OA #openaccess #IDEAS #coproduction #patients #partners #research

A diagram with seven blue circles describing the different items within a patient-researcher research cycle. The seven blue circles include: designing and managing, undertaking, disseminating, implementing, evaluating impact, prioritising and commissioning

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The Lancet @thelancet.com · Apr 25

The RTS,S/AS01E malaria vaccine has been successfully administered to over 2 million children since 2019.

On #WorldMalariaDay, a paper in @lancetgh.bsky.social reports the results of a study evaluating RTS,S/AS01E safety and effectiveness in real-world settings: tinyurl.com/3jthn39h

Research in context panel for The Lancet Global Health article "Safety of RTS,S/AS01E malaria vaccine up to 1 year after the third dose in Ghana, Kenya, and Malawi (EPI-MAL-003): a phase 4 cohort event monitoring study". Copyright: 2025 GSK plc. Published by Elsevier Ltd. CC By 4.0.

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The Health Foundation @healthfoundation.bsky.social · Apr 16

Electronic patient records (EPRs) can potentially transform health care delivery, improving quality, efficiency and patient safety. Most trusts in England now have EPRs but many are not yet using them to their full potential.

We explored the challenges in our recent analysis ⬇️

Electronic patient records: why the NHS urgently needs a strategy to reap the benefits

Our qualitative research with five acute NHS trusts and a US medical centre investigates the current state of EPR adoption and use, and what it takes to really see the benefits.

bit.ly

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SMT Evidence @smtevidence.com · Apr 15

Out of the top 25 most-cited papers in the 21st century, the #PRISMA statement comes in at number 6 with a mind-boggling 133,965 citations according to Web of Science.

www.nature.com/articles/d41...

H/T @nature.com

#systematicreviews #evidence #evidencesynthesis #statistics #data #citations

Exclusive: the most-cited papers of the twenty-first century

A Nature analysis reveals the 25 highest-cited papers published this century and explores why they are breaking records.

www.nature.com

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