SMT Evidence
@smtevidence.com
Helping industry and academic partners generate the evidence they need to successfully bring their new drugs and technologies to market www.smtevidence.com
Day 2️⃣ of the @nihr-io.bsky.social Futures, Foresight & Horizon Scanning conference has been absolutely jam-packed with great science!
We kicked off with a thought-provoking keynote, followed a great range of talks - from new start-up projects to horizon scanning in the wearables space.
#FFHSC
We kicked off with a thought-provoking keynote, followed a great range of talks - from new start-up projects to horizon scanning in the wearables space.
#FFHSC
November 20, 2025 at 8:08 PM
Day 2️⃣ of the @nihr-io.bsky.social Futures, Foresight & Horizon Scanning conference has been absolutely jam-packed with great science!
We kicked off with a thought-provoking keynote, followed a great range of talks - from new start-up projects to horizon scanning in the wearables space.
#FFHSC
We kicked off with a thought-provoking keynote, followed a great range of talks - from new start-up projects to horizon scanning in the wearables space.
#FFHSC
A fantastic first day today at the @nihr-io.bsky.social Futures, Foresight & Horizon Scanning conference!
Really interesting range of talks, and lots of engaging, in-depth insights and methodologies on display.
Can’t wait for day two!
#FFHSC
Really interesting range of talks, and lots of engaging, in-depth insights and methodologies on display.
Can’t wait for day two!
#FFHSC
November 19, 2025 at 5:45 PM
A fantastic first day today at the @nihr-io.bsky.social Futures, Foresight & Horizon Scanning conference!
Really interesting range of talks, and lots of engaging, in-depth insights and methodologies on display.
Can’t wait for day two!
#FFHSC
Really interesting range of talks, and lots of engaging, in-depth insights and methodologies on display.
Can’t wait for day two!
#FFHSC
Very excited to be off to the @nihr-io.bsky.social Futures, Foresight & Horizon Scanning conference on 19th-20th November!
Looking forward to lots of great talks - the lightning sessions especially sound fantastic ⚡️⚡️⚡️
Please do shout if you are going along - would be great to say hello 👋
#FFHSC25
Looking forward to lots of great talks - the lightning sessions especially sound fantastic ⚡️⚡️⚡️
Please do shout if you are going along - would be great to say hello 👋
#FFHSC25
November 7, 2025 at 12:47 PM
Very excited to be off to the @nihr-io.bsky.social Futures, Foresight & Horizon Scanning conference on 19th-20th November!
Looking forward to lots of great talks - the lightning sessions especially sound fantastic ⚡️⚡️⚡️
Please do shout if you are going along - would be great to say hello 👋
#FFHSC25
Looking forward to lots of great talks - the lightning sessions especially sound fantastic ⚡️⚡️⚡️
Please do shout if you are going along - would be great to say hello 👋
#FFHSC25
A new #systematicreview and #networkmetaanalysis shows that antidepressants differ markedly in their physiological effects, with substantial differences in parameters such as weight, cholesterol, heart rate, blood pressure
www.thelancet.com/journals/lan...
@thelancet.com
#OA #depression #NMA
www.thelancet.com/journals/lan...
@thelancet.com
#OA #depression #NMA
October 28, 2025 at 10:59 AM
A new #systematicreview and #networkmetaanalysis shows that antidepressants differ markedly in their physiological effects, with substantial differences in parameters such as weight, cholesterol, heart rate, blood pressure
www.thelancet.com/journals/lan...
@thelancet.com
#OA #depression #NMA
www.thelancet.com/journals/lan...
@thelancet.com
#OA #depression #NMA
Happy Ada Lovelace Day! Enjoy this annual international celebration of the achievements of women in science, technology, engineering and maths (STEM).
findingada.com
findingada.com
Ada Lovelace Day – Celebrating the achievements of women in science, technology, engineering and maths
findingada.com
October 14, 2025 at 4:58 PM
Happy Ada Lovelace Day! Enjoy this annual international celebration of the achievements of women in science, technology, engineering and maths (STEM).
findingada.com
findingada.com
“The most important thing about #AI isn't its technical capabilities or limitations. The most important thing is the investor story and the ensuing mania that has teed up an economical catastrophe that will harm hundreds of millions or even billions of people.”
pluralistic.net/2025/09/27/e...
pluralistic.net/2025/09/27/e...
Pluralistic: The real (economic) AI apocalypse is nigh (27 Sep 2025) – Pluralistic: Daily links from Cory Doctorow
pluralistic.net
October 10, 2025 at 9:23 AM
“The most important thing about #AI isn't its technical capabilities or limitations. The most important thing is the investor story and the ensuing mania that has teed up an economical catastrophe that will harm hundreds of millions or even billions of people.”
pluralistic.net/2025/09/27/e...
pluralistic.net/2025/09/27/e...
A microsimulation model to estimate the impact of care disruption during the COVID-19 pandemic on breast cancer mortality using an administrative database.
www.jclinepi.com/article/S089...
Via @jclinepi.bsky.social
www.jclinepi.com/article/S089...
Via @jclinepi.bsky.social
A microsimulation model based on healthcare pathways to estimate the impact of COVID-19 pandemic–induced delays on breast cancer mortality
This study aimed to develop a microsimulation model to estimate the impact of a care
disruption during the COVID-19 pandemic on breast cancer mortality using an administrative
database.
www.jclinepi.com
October 8, 2025 at 3:42 PM
A microsimulation model to estimate the impact of care disruption during the COVID-19 pandemic on breast cancer mortality using an administrative database.
www.jclinepi.com/article/S089...
Via @jclinepi.bsky.social
www.jclinepi.com/article/S089...
Via @jclinepi.bsky.social
Reposted by SMT Evidence
ACOG reaffirms that acetaminophen is safe for managing pain and fever during pregnancy. No reputable studies support suggestions like those in HHS’s recent announcement linking acetaminophen use in pregnancy to autism; in fact, high-quality studies show no such risk. https://bit.ly/47Wxc59
September 22, 2025 at 9:24 PM
ACOG reaffirms that acetaminophen is safe for managing pain and fever during pregnancy. No reputable studies support suggestions like those in HHS’s recent announcement linking acetaminophen use in pregnancy to autism; in fact, high-quality studies show no such risk. https://bit.ly/47Wxc59
Reposted by SMT Evidence
🚨Emerging Point-of-Care Testing in Genomics
Exploring the development pipeline of genomic POCTs designed to identify variations in the genome & epigenome, supporting diagnosis, prognosis & treatment decisions across clinical areas👉 ow.ly/UB2R50WQcvo @newcastleuni.bsky.social @nihr.bsky.social
Exploring the development pipeline of genomic POCTs designed to identify variations in the genome & epigenome, supporting diagnosis, prognosis & treatment decisions across clinical areas👉 ow.ly/UB2R50WQcvo @newcastleuni.bsky.social @nihr.bsky.social
September 3, 2025 at 9:21 AM
🚨Emerging Point-of-Care Testing in Genomics
Exploring the development pipeline of genomic POCTs designed to identify variations in the genome & epigenome, supporting diagnosis, prognosis & treatment decisions across clinical areas👉 ow.ly/UB2R50WQcvo @newcastleuni.bsky.social @nihr.bsky.social
Exploring the development pipeline of genomic POCTs designed to identify variations in the genome & epigenome, supporting diagnosis, prognosis & treatment decisions across clinical areas👉 ow.ly/UB2R50WQcvo @newcastleuni.bsky.social @nihr.bsky.social
The contribution of conference abstracts in #systematicreviews - "Their inclusion changed the effect estimate in 55.6% and imprecision in 16% of cases when using MIDs. In a few instances, CAs also influenced RoB and inconsistency assessments."
www.jclinepi.com/article/S089...
@jclinepi.bsky.social
www.jclinepi.com/article/S089...
@jclinepi.bsky.social
Including conference abstracts rarely changed systematic review conclusions: a case study from a living network meta-analysis of COVID-19 treatments
Including conference abstracts (CAs) in systematic reviews (SRs) helps reduce publication
bias but raises concerns about reporting quality and reliability. While discrepancies
with full publications a...
www.jclinepi.com
September 14, 2025 at 11:21 AM
The contribution of conference abstracts in #systematicreviews - "Their inclusion changed the effect estimate in 55.6% and imprecision in 16% of cases when using MIDs. In a few instances, CAs also influenced RoB and inconsistency assessments."
www.jclinepi.com/article/S089...
@jclinepi.bsky.social
www.jclinepi.com/article/S089...
@jclinepi.bsky.social
Reposted by SMT Evidence
Most Americans still don’t know that #alcohol can cause #cancer — and the alcohol industry and Trump are working hard to make sure it stays that way by discrediting and burying a new report that offers new evidence of the link between drinking alcohol and dying www.vox.com/health/46008... @vox.com
Exclusive: RFK Jr. and the White House buried a major study on alcohol and cancer. Here’s what it shows.
Kennedy wants to “Make America Healthy Again” — but doesn’t want you to see a report that could do just that.
www.vox.com
September 4, 2025 at 2:43 PM
Most Americans still don’t know that #alcohol can cause #cancer — and the alcohol industry and Trump are working hard to make sure it stays that way by discrediting and burying a new report that offers new evidence of the link between drinking alcohol and dying www.vox.com/health/46008... @vox.com
Reposted by SMT Evidence
In a new #ScienceExpertVoices article, Seth Berkley unravels the arc of vaccine progress. https://scim.ag/3VrCDBx
September 2, 2025 at 5:10 PM
In a new #ScienceExpertVoices article, Seth Berkley unravels the arc of vaccine progress. https://scim.ag/3VrCDBx
Reposted by SMT Evidence
Most air cleaning devices have not been tested on people, and little is known about their potential harms. Professors of medicine and public health explain:
Most air cleaning devices have not been tested on people − and little is known about their potential harms, new study finds
Manufacturers often make bold claims about how well these technologies work. Better testing would allow consumers and institutions to pick the most effective ones.
buff.ly
August 20, 2025 at 10:03 PM
Most air cleaning devices have not been tested on people, and little is known about their potential harms. Professors of medicine and public health explain:
New #research that could help clinical trials avoid early termination.
Identifying predictors of early trial termination: a meta-epidemiological study utilising elements of the research ethics committee evaluation.
www.jclinepi.com/article/S089...
Via @jclinepi.bsky.social
Identifying predictors of early trial termination: a meta-epidemiological study utilising elements of the research ethics committee evaluation.
www.jclinepi.com/article/S089...
Via @jclinepi.bsky.social
August 20, 2025 at 10:02 AM
New #research that could help clinical trials avoid early termination.
Identifying predictors of early trial termination: a meta-epidemiological study utilising elements of the research ethics committee evaluation.
www.jclinepi.com/article/S089...
Via @jclinepi.bsky.social
Identifying predictors of early trial termination: a meta-epidemiological study utilising elements of the research ethics committee evaluation.
www.jclinepi.com/article/S089...
Via @jclinepi.bsky.social
A really thought-provoking article from @elife.bsky.social about manuscript publication, peer review and who acts as the gatekeepers of publishing: “why are indexers unable to see that peer review can be more than a thumbs up or a thumbs down?” sfdora.org/2025/07/30/s... H/T @hildabast.bsky.social
Why are indexers unable to see that peer review can be more than a thumbs up or a thumbs down? | DORA
Journals and peer review are unlikely to change for the better if the companies that operate scientific indexes and citation databases continue to stifle innovation. At eLife we believe that the conte...
sfdora.org
August 6, 2025 at 11:36 AM
A really thought-provoking article from @elife.bsky.social about manuscript publication, peer review and who acts as the gatekeepers of publishing: “why are indexers unable to see that peer review can be more than a thumbs up or a thumbs down?” sfdora.org/2025/07/30/s... H/T @hildabast.bsky.social
Reposted by SMT Evidence
A Review in Nature Reviews Endocrinology assesses the role of ultra-processed foods in obesity, examining the epidemiological evidence, biological mechanisms and implications for policymakers. go.nature.com/44zGHoO 🍎📃 #medsky 🧪
July 25, 2025 at 1:46 AM
A Review in Nature Reviews Endocrinology assesses the role of ultra-processed foods in obesity, examining the epidemiological evidence, biological mechanisms and implications for policymakers. go.nature.com/44zGHoO 🍎📃 #medsky 🧪
Reposted by SMT Evidence
In human beings, egg cells need to survive for about five decades, much longer than most other cell types – and they may achieve this unusually long lifespan by slowing down their natural cell processes.
How human eggs stay fresh for decades
In human beings, egg cells need to survive for about five decades, much longer than most other cell types – and they may achieve this unusually long lifespan by slowing down their natural cell processes
www.newscientist.com
July 20, 2025 at 4:38 PM
In human beings, egg cells need to survive for about five decades, much longer than most other cell types – and they may achieve this unusually long lifespan by slowing down their natural cell processes.
Reposted by SMT Evidence
#SupportOLSPub - every vote counts
The first giant steps have been taken, the OLSPub application has been submitted. For all those who, as researchers, information specialists or simply as people, would like to position themselves, everyone can leave a signature here.
blog.zbmed.de/olspub-support
The first giant steps have been taken, the OLSPub application has been submitted. For all those who, as researchers, information specialists or simply as people, would like to position themselves, everyone can leave a signature here.
blog.zbmed.de/olspub-support
OLSPub support – ZB MED-Blog
Support for the project OLSPub - Open Life Science Publications Database as individuals.
blog.zbmed.de
June 12, 2025 at 11:19 AM
#SupportOLSPub - every vote counts
The first giant steps have been taken, the OLSPub application has been submitted. For all those who, as researchers, information specialists or simply as people, would like to position themselves, everyone can leave a signature here.
blog.zbmed.de/olspub-support
The first giant steps have been taken, the OLSPub application has been submitted. For all those who, as researchers, information specialists or simply as people, would like to position themselves, everyone can leave a signature here.
blog.zbmed.de/olspub-support
Reposted by SMT Evidence
The MAHA report critique, by @hiltzikm.bsky.social
www.latimes.com/business/sto...
And the Trojan horse, by @drjengunter.bsky.social
vajenda.substack.com/p/hijacking-...
www.latimes.com/business/sto...
And the Trojan horse, by @drjengunter.bsky.social
vajenda.substack.com/p/hijacking-...
June 4, 2025 at 3:19 PM
The MAHA report critique, by @hiltzikm.bsky.social
www.latimes.com/business/sto...
And the Trojan horse, by @drjengunter.bsky.social
vajenda.substack.com/p/hijacking-...
www.latimes.com/business/sto...
And the Trojan horse, by @drjengunter.bsky.social
vajenda.substack.com/p/hijacking-...
Reposted by SMT Evidence
The remarkable benefit of exercise was just extended to improved survival after cancer in a randomized trial
@nejm.org
nejm.org/doi/full/10....
@nejm.org
nejm.org/doi/full/10....
June 1, 2025 at 2:52 PM
The remarkable benefit of exercise was just extended to improved survival after cancer in a randomized trial
@nejm.org
nejm.org/doi/full/10....
@nejm.org
nejm.org/doi/full/10....
In the wake of several countries legalising #marijuana, questions remain about the drug's long-term #health effects. A new study has found that people who smoke weed or use edibles do worse on measures of vascular health that predict cardiovascular risk.
jamanetwork.com/journals/jam...
@jama.com
jamanetwork.com/journals/jam...
@jama.com
Endothelial Dysfunction and Chronic Cannabis Use
This cross-sectional study aims to determine whether cannabis use is associated with vascular endothelial function.
jamanetwork.com
May 29, 2025 at 11:45 AM
In the wake of several countries legalising #marijuana, questions remain about the drug's long-term #health effects. A new study has found that people who smoke weed or use edibles do worse on measures of vascular health that predict cardiovascular risk.
jamanetwork.com/journals/jam...
@jama.com
jamanetwork.com/journals/jam...
@jama.com
A scoping review of carbon emissions associated with clinical trials finds that several trial activities, including travel and meetings, trial facilities, and sample & lab activities, are consistently carbon heavy.
www.jclinepi.com/article/S089...
@jclinepi.bsky.social
#scopingreview #openaccess
www.jclinepi.com/article/S089...
@jclinepi.bsky.social
#scopingreview #openaccess
May 23, 2025 at 10:41 AM
A scoping review of carbon emissions associated with clinical trials finds that several trial activities, including travel and meetings, trial facilities, and sample & lab activities, are consistently carbon heavy.
www.jclinepi.com/article/S089...
@jclinepi.bsky.social
#scopingreview #openaccess
www.jclinepi.com/article/S089...
@jclinepi.bsky.social
#scopingreview #openaccess
Brand new SPIRIT and CONSORT #reporting #guidelines are out now!
🎯 CONSORT 2025 for reporting RCTs now has a 30-item checklist
🎯 SPIRIT 2025 for reporting trial protocols now has a 34-item checklist
www.jclinepi.com/article/S089...
@jclinepi.bsky.social
#SPIRIT #CONSORT #RCTs #protocols
🎯 CONSORT 2025 for reporting RCTs now has a 30-item checklist
🎯 SPIRIT 2025 for reporting trial protocols now has a 34-item checklist
www.jclinepi.com/article/S089...
@jclinepi.bsky.social
#SPIRIT #CONSORT #RCTs #protocols
May 18, 2025 at 10:14 AM
Brand new SPIRIT and CONSORT #reporting #guidelines are out now!
🎯 CONSORT 2025 for reporting RCTs now has a 30-item checklist
🎯 SPIRIT 2025 for reporting trial protocols now has a 34-item checklist
www.jclinepi.com/article/S089...
@jclinepi.bsky.social
#SPIRIT #CONSORT #RCTs #protocols
🎯 CONSORT 2025 for reporting RCTs now has a 30-item checklist
🎯 SPIRIT 2025 for reporting trial protocols now has a 34-item checklist
www.jclinepi.com/article/S089...
@jclinepi.bsky.social
#SPIRIT #CONSORT #RCTs #protocols
Reposted by SMT Evidence
What makes a good guideline? – A systematic review and analysis of 120 clinical practice guidelines using the AGREE II tool - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
What makes a good guideline? – A systematic review and analysis of 120 clinical practice guidelines using the AGREE II tool
Clinical practice guidelines (CPGs) translate evidence into actionable recommendations
to enhance care quality, improve clinical outcomes, reduce treatment variations, and
make healthcare delivery mor...
www.jclinepi.com
May 17, 2025 at 7:28 PM
What makes a good guideline? – A systematic review and analysis of 120 clinical practice guidelines using the AGREE II tool - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
A new reporting guideline has just been published for the involvement of patients and caregivers in identifying and designing healthcare interventions: the IDEAS framework www.jclinepi.com/article/S089... HT @jclinepi.bsky.social #OA #openaccess #IDEAS #coproduction #patients #partners #research
May 11, 2025 at 2:12 PM
A new reporting guideline has just been published for the involvement of patients and caregivers in identifying and designing healthcare interventions: the IDEAS framework www.jclinepi.com/article/S089... HT @jclinepi.bsky.social #OA #openaccess #IDEAS #coproduction #patients #partners #research