Spang Lab
@spanglab.bsky.social
We are scientists interested in understanding the basics of how a cell, the building block of our body, works.
@biozentrum
@UniBasel_en
#cellbio #Biozentrum #RNA #organelles #membranes #aging #stress #proteostasis #signaling
@biozentrum
@UniBasel_en
#cellbio #Biozentrum #RNA #organelles #membranes #aging #stress #proteostasis #signaling
A little stress is good for you in #health #ageing ! #Diet is important! Take a look at our article with Emmanouil Kyriakakis as 1st author!
@unibas.ch
@natcomms.nature.com
@snsf.ch
#Longevity #healthspan
rdcu.be/eI1vZ
@unibas.ch
@natcomms.nature.com
@snsf.ch
#Longevity #healthspan
rdcu.be/eI1vZ
Bacterial RNA promotes proteostasis through inter-tissue communication in C. elegans
Nature Communications - Kyriakakis et al. show that bacterial RNA can improve C. elegans healthspan and reduce toxic protein aggregation in muscles. This depends on inter-tissue communication and...
rdcu.be
October 1, 2025 at 5:14 PM
A little stress is good for you in #health #ageing ! #Diet is important! Take a look at our article with Emmanouil Kyriakakis as 1st author!
@unibas.ch
@natcomms.nature.com
@snsf.ch
#Longevity #healthspan
rdcu.be/eI1vZ
@unibas.ch
@natcomms.nature.com
@snsf.ch
#Longevity #healthspan
rdcu.be/eI1vZ
Reposted by Spang Lab
We are thankful to our collaborators from the @spanglab.bsky.social and @maierlab.bsky.social @biozentrum.unibas.ch @unibas.ch
August 11, 2025 at 9:10 AM
We are thankful to our collaborators from the @spanglab.bsky.social and @maierlab.bsky.social @biozentrum.unibas.ch @unibas.ch
Great collaboration with Liza Malong and Filip Roudnicky from pRED @Roche rdcu.be/et6Nw
A CRISPR/Cas9 screen reveals proteins at the endosome-Golgi interface that modulate cellular anti-sense oligonucleotide activity
Nature Communications - Antisense oligonucleotide (ASO) cellular activity requires endosomal escape. Here, the authors show that disrupting Golgi-endosome protein AP1M1 enhances ASO activity by...
rdcu.be
June 30, 2025 at 3:30 PM
Great collaboration with Liza Malong and Filip Roudnicky from pRED @Roche rdcu.be/et6Nw
Reposted by Spang Lab
Congratulations to Anne Spang @spanglab.bsky.social for being elected as a new #AAASFellow by @aaas.org ! The world’s largest scientific society recognizes her outstanding contributions to the field of cell #biology and #biochemistry. @unibas.ch
www.biozentrum.unibas.ch/news/detail/...
www.biozentrum.unibas.ch/news/detail/...
Anne Spang awarded distinction of AAAS Fellow
The AAAS has elected Prof. Anne Spang at the Biozentrum, University of Basel, as a Fellow. With this honor, the world’s largest scientific society recognizes her outstanding contributions to the field...
www.biozentrum.unibas.ch
March 28, 2025 at 8:17 AM
Congratulations to Anne Spang @spanglab.bsky.social for being elected as a new #AAASFellow by @aaas.org ! The world’s largest scientific society recognizes her outstanding contributions to the field of cell #biology and #biochemistry. @unibas.ch
www.biozentrum.unibas.ch/news/detail/...
www.biozentrum.unibas.ch/news/detail/...
In issue 6:
Commentary: organoids for decoding host-microbe interactions
Importance of mitochondrial DNA elimination during spermatogenesis
How kinesin KIF12 promotes steatohepatitis
Cancer cell adaptation strategies to aneuploidy
Cover: Daniel Ott, Anne Spang et al
www.embopress.org/toc/14602075...
Commentary: organoids for decoding host-microbe interactions
Importance of mitochondrial DNA elimination during spermatogenesis
How kinesin KIF12 promotes steatohepatitis
Cancer cell adaptation strategies to aneuploidy
Cover: Daniel Ott, Anne Spang et al
www.embopress.org/toc/14602075...
March 17, 2025 at 3:18 PM
Awesome lab outing: snow shoeing and sledding! Thank you for being such a wonderful team!
February 28, 2025 at 9:42 AM
Awesome lab outing: snow shoeing and sledding! Thank you for being such a wonderful team!
Interested how events are coordinated during #endosome maturation? Check out our latest paper! Congrats Daniel, Samit and Jachen!
www.embopress.org/doi/full/10....
www.embopress.org/doi/full/10....
Coordination between ESCRT function and Rab conversion during endosome maturation | The EMBO Journal
imageimageEarly endosome maturation requires Rab conversion and ESCRT function; however, how
these processes are coordinated remains largely elusive. This study proposes that
Rab conversion in both C....
www.embopress.org
February 5, 2025 at 3:53 PM
Interested how events are coordinated during #endosome maturation? Check out our latest paper! Congrats Daniel, Samit and Jachen!
www.embopress.org/doi/full/10....
www.embopress.org/doi/full/10....
I feel humble and honored to receive the Lelio Orci Award 2024. I want to thank my amazing co-workers and trainees who are with me on the pursuit of the understanding how intracellular communication is achieved.
Congratulations to Anne Spang for receiving the renowned Lelio Orci Award.
The award honors her pioneering work in intracellular organization and her research achievements in Cell Biology. @unibas.ch
www.biozentrum.unibas.ch/news/detail/...
The award honors her pioneering work in intracellular organization and her research achievements in Cell Biology. @unibas.ch
www.biozentrum.unibas.ch/news/detail/...
January 14, 2025 at 4:42 PM
I feel humble and honored to receive the Lelio Orci Award 2024. I want to thank my amazing co-workers and trainees who are with me on the pursuit of the understanding how intracellular communication is achieved.