Stephanie Orchanian
stephorch.bsky.social
Stephanie Orchanian
@stephorch.bsky.social
UCLA Chancellor’s Postdoctoral Fellow studying the maternal gut microbiome
Reposted by Stephanie Orchanian
Excited to share new work by Guli Agirman + co that identifies a direct mechanism linking gut microbial imidazole propionate to stress! 🧠🦠 Btw this image was made by Nano Banana Pro 🍌. First time I've gotten a model to accurately generate a science graphic 🤯 authors.elsevier.com/a/1mA5M6t8JE...
November 25, 2025 at 5:45 PM
Excited to share our recent publication in this month's issue of mBio, based on my PhD research. We show that replication of 𝘛. 𝘨𝘰𝘯𝘥𝘪𝘪 is required to trigger a localized immune response in the brain! 🧠 bit.ly/3TA9ALj
Toxoplasma gondii parasites induce a localized myeloid cell immune response surrounding parasites in the brain during acute infection | mBio
Toxoplasma gondii is a brain-infecting parasite, and the mobilization of peripheral immune cells to the brain is critical for controlling T. gondii infection. However, the initial events driving these...
bit.ly
July 10, 2025 at 5:22 PM
Reposted by Stephanie Orchanian
Thrilled to share this collaborative work by Kristie Yu, Francis Chandra, Amina Schartup and teams @Scripps_Ocean and @UCLA showing that an engineered gut bacterium can be used to reduce the neurotoxic effects of dietary methylmercury www.cell.com/cell-host-mi...
An engineered gut bacterium protects against dietary methylmercury exposure in pregnant mice
Yu and Chandra et al. engineered a commensal gut microbe, Bacteroides thetaiotaomicron, to detoxify methylmercury (MeHg). The engineered bacterium reduces MeHg in the intestinal lumen, limits its accu...
www.cell.com
May 2, 2025 at 2:08 AM
Reposted by Stephanie Orchanian
Maternal microbiome is a cornerstone of maternal and fetal health. https://buff.ly/431YoNu

@stephorch.bsky.social‬ & @pipethero.bsky.social highlight gut microbiome x environmental interactions at the maternal-fetal interface that influence the brains of pregnant people and developing offspring.
February 20, 2025 at 4:33 PM
Curious about how the gut microbiome modulates the neurological health of pregnant women and their offspring? Check out my recent review with @pipethero.bsky.social out now @jclinical-invest.bsky.social! 🦠🤰👶🧠

www.jci.org/articles/vie...
JCI - The microbiome as a modulator of neurological health across the maternal-offspring interface
www.jci.org
February 17, 2025 at 9:51 PM