Kristoffer Krogerus
@suregork.bsky.social
Senior Scientist at VTT Finland. I work with yeast and beer.
Reposted by Kristoffer Krogerus
✨ Latest exciting story of the group in @nature.com. Here, we go beyond SNPs and built a species-wide atlas of genetic variants in yeast. With >1,000 near T2T genomes, we show how large genomic variations affect trait diversity.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
From genotype to phenotype with 1,086 near telomere-to-telomere yeast genomes - Nature
A newly compiled atlas of species-wide structural variants and gene-based and graph pangenomes derived from highly complete assemblies of genomes from 1,086 natural isolates enable integrative genome-...
www.nature.com
October 16, 2025 at 7:49 AM
✨ Latest exciting story of the group in @nature.com. Here, we go beyond SNPs and built a species-wide atlas of genetic variants in yeast. With >1,000 near T2T genomes, we show how large genomic variations affect trait diversity.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Kristoffer Krogerus
Incredible new paper from @schacherer.bsky.social et al rdcu.be/eLcTH
From genotype to phenotype with 1,086 near telomere-to-telomere yeast genomes
Nature - A newly compiled atlas of species-wide structural variants and gene-based and graph pangenomes derived from highly complete assemblies of genomes from 1,086 natural isolates enable...
rdcu.be
October 15, 2025 at 9:06 PM
Incredible new paper from @schacherer.bsky.social et al rdcu.be/eLcTH
Reposted by Kristoffer Krogerus
New preprint from the lab: we show that the ability to switch mating type was lost at least 13 times independently in the evolution of S. cerevisiae. At least 27% of isolates are heterothallic with a strong association with polyploidy and heterozygosity
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Repeated losses of self-fertility shaped heterozygosity and polyploidy in yeast evolution
Evolutionary transitions in mating strategy have profound consequences for genetic variation and adaptation. In Saccharomyces cerevisiae, mating-type switching is a central feature of the life cycle t...
www.biorxiv.org
September 16, 2025 at 6:42 PM
New preprint from the lab: we show that the ability to switch mating type was lost at least 13 times independently in the evolution of S. cerevisiae. At least 27% of isolates are heterothallic with a strong association with polyploidy and heterozygosity
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Kristoffer Krogerus
Delighted to see @sakshikhaiwal.bsky.social work in print www.embopress.org/doi/full/10....
Huge thank to @univcotedazur.bsky.social for providing extensive support on this project, @pedrobeltrao.bsky.social and Jonas groups for huge help, @cnrs.fr @ircan.bsky.social
Huge thank to @univcotedazur.bsky.social for providing extensive support on this project, @pedrobeltrao.bsky.social and Jonas groups for huge help, @cnrs.fr @ircan.bsky.social
Predicting natural variation in the yeast phenotypic landscape with machine learning | Molecular Systems Biology
imageimageAn ensemble of phenotypes measured in the genome-sequenced 1,011 S. cerevisiae collection were coupled with genomics and molecular-level data to benchmark machine learning models for quantitative phenotypic predictions at scale. Large-...
www.embopress.org
September 1, 2025 at 9:13 AM
Delighted to see @sakshikhaiwal.bsky.social work in print www.embopress.org/doi/full/10....
Huge thank to @univcotedazur.bsky.social for providing extensive support on this project, @pedrobeltrao.bsky.social and Jonas groups for huge help, @cnrs.fr @ircan.bsky.social
Huge thank to @univcotedazur.bsky.social for providing extensive support on this project, @pedrobeltrao.bsky.social and Jonas groups for huge help, @cnrs.fr @ircan.bsky.social
Ten postdoc positions available at VTT in various fields, including one on bioprocess modelling and one on automated fungal strain construction. ats.talentadore.com/apply/apply-...
August 2, 2025 at 6:59 AM
Ten postdoc positions available at VTT in various fields, including one on bioprocess modelling and one on automated fungal strain construction. ats.talentadore.com/apply/apply-...
Reposted by Kristoffer Krogerus
🚨 We're hiring! 🚨
A 2-year postdoc position is now open in our lab to explore the fascinating world of yeast polyploid genomes, their structure, stability, and adaptive potential.
🔗 More info here:
docs.google.com/document/d/1...
Please repost!
#Postdoc #Genomics #Yeast #Polyploidy #Evolution
A 2-year postdoc position is now open in our lab to explore the fascinating world of yeast polyploid genomes, their structure, stability, and adaptive potential.
🔗 More info here:
docs.google.com/document/d/1...
Please repost!
#Postdoc #Genomics #Yeast #Polyploidy #Evolution
Postdoc_Evol_Genomics_Sorbonne.docx
Postdoctoral position in Yeast Evolutionary Genomics Hosting unit Laboratory of Computational, Quantitative, and Synthetic Biology (CQSB). The CQSB is an interdisciplinary research unit within the ...
docs.google.com
May 19, 2025 at 3:41 PM
🚨 We're hiring! 🚨
A 2-year postdoc position is now open in our lab to explore the fascinating world of yeast polyploid genomes, their structure, stability, and adaptive potential.
🔗 More info here:
docs.google.com/document/d/1...
Please repost!
#Postdoc #Genomics #Yeast #Polyploidy #Evolution
A 2-year postdoc position is now open in our lab to explore the fascinating world of yeast polyploid genomes, their structure, stability, and adaptive potential.
🔗 More info here:
docs.google.com/document/d/1...
Please repost!
#Postdoc #Genomics #Yeast #Polyploidy #Evolution
Really excited to see this one out! I was involved in this joint study with @briangibsontub.bsky.social, Nubia G-V, Mathias H, helping with sequencing and genomics. We characterize strains isolated from Ecuadorian maize chicha, and found many diastatic strains carrying STA1! doi.org/10.1016/j.fm...
Genetic pre-adaptations in Saccharomyces cerevisiae Andean chicha isolates facilitate industrial brewery application
Strains of Saccharomyces cerevisiae were isolated from a traditionally produced Andean maize-based chicha from Ecuador and characterised with respect …
www.sciencedirect.com
May 15, 2025 at 12:21 PM
Really excited to see this one out! I was involved in this joint study with @briangibsontub.bsky.social, Nubia G-V, Mathias H, helping with sequencing and genomics. We characterize strains isolated from Ecuadorian maize chicha, and found many diastatic strains carrying STA1! doi.org/10.1016/j.fm...
Reposted by Kristoffer Krogerus
Creating Better Brewing #Yeast With the 1011 Yeast Genomes Data Sets: @suregork.bsky.social & Nils Rettberg reanalyze large-scale ‘omics’ data sets to identify strains with better #brewing performance 🍺🍺🍺
onlinelibrary.wiley.com/doi/full/10....
onlinelibrary.wiley.com/doi/full/10....
Creating Better Brewing Yeast With the 1011 Yeast Genomes Data Sets
An overview of how large-scale omics data sets can be exploited for brewing yeast strain development.
onlinelibrary.wiley.com
February 19, 2025 at 6:22 PM
Creating Better Brewing #Yeast With the 1011 Yeast Genomes Data Sets: @suregork.bsky.social & Nils Rettberg reanalyze large-scale ‘omics’ data sets to identify strains with better #brewing performance 🍺🍺🍺
onlinelibrary.wiley.com/doi/full/10....
onlinelibrary.wiley.com/doi/full/10....
Interested in how omics data sets can be used for brewing yeast development? Here is a short overview how recent data sets derived from the 1011 yeast genomes project can be used to identify potentially interesting strains for brewing.
doi.org/10.1002/yea.... #yeast #saccharomyces #beer
doi.org/10.1002/yea.... #yeast #saccharomyces #beer
Creating Better Brewing Yeast With the 1011 Yeast Genomes Data Sets
An overview of how large-scale omics data sets can be exploited for brewing yeast strain development.
doi.org
February 17, 2025 at 6:47 PM
Interested in how omics data sets can be used for brewing yeast development? Here is a short overview how recent data sets derived from the 1011 yeast genomes project can be used to identify potentially interesting strains for brewing.
doi.org/10.1002/yea.... #yeast #saccharomyces #beer
doi.org/10.1002/yea.... #yeast #saccharomyces #beer
Has anyone ever notice peptone brand would influence antibiotic resistance in #yeast? We suddenly started having issues with our transformations with NAT and HYG selection (no colonies appearing with plasmids that have worked well before).
January 31, 2025 at 10:37 AM
Has anyone ever notice peptone brand would influence antibiotic resistance in #yeast? We suddenly started having issues with our transformations with NAT and HYG selection (no colonies appearing with plasmids that have worked well before).