The Tidgewell Research Lab
@thetidgelab.bsky.social
490 followers 260 following 22 posts
Drug Discovery Lab at the University of Kentucky College of Pharmacy We do natural products discovery and medicinal chemistry synthesis to develop new compounds to treat and understand CNS disorders Account ran by KJT
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roszenil.bsky.social
The Department of Biology at the University of Kentucky is hiring a Microbiologist (broadly defined). Microbial eco-evo folks, this is your sign to come work with us. Not in the search committee, but happy to answer questions.
ukjobs.uky.edu/postings/600...
#microbiology #ecology
Assistant or Associate Professor in Microbiology
The Department of Biology in the College of Arts and Sciences at the University of Kentucky in Lexington, KY seeks to fill a tenure-eligible faculty position at the Assistant or Associate Professor le...
ukjobs.uky.edu
thetidgelab.bsky.social
Fun to start the day off today with a departmental seminar by one of the grad students in the lab.
FLyer listing title and location for a seminar within the Department of Pharmaceutical Sciences at the University of Kentucky. Includes an image of the graduate student presenter.
thetidgelab.bsky.social
Back in New Hampshire for some fun at the GRC Bioactives and Natural Products!! Stoked for a week of science and walking in the woods and more science
thetidgelab.bsky.social
So I was doing some account balancing today and just noticed the Sigma is adding a "Tarriff" Charge onto our most recent orders ... anyone else notice that? #chemsky
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jeremymberg.bsky.social
A short Bluetorial about my early days as the Director of the National Institute of General Medical Sciences (NIGMS) at NIH.

The importance of feeling responsibility and taking pride in doing the best job you can
a cartoon says hey everybody an old man 's talking while bart simpson looks on
ALT: a cartoon says hey everybody an old man 's talking while bart simpson looks on
media.tenor.com
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erictopol.bsky.social
Summary Table of the massive defunding of biomedical research in the United States
www.nytimes.com/interactive/...
Reposted by The Tidgewell Research Lab
thetidgelab.bsky.social
Lab earned a gold star today! Way to go team, keep up the hard work
@ukresearch.bsky.social
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sethabramson.bsky.social
Here is the dirty secret no one is speaking out loud: Trump does not believe that bombing the hell out of Iran is going to send Iran back to the negotiation table, nor has anyone in his inner circle suggested to him that outcome.

He fully knows he has entered America into a war.
thetidgelab.bsky.social
My new favorite one are www.nature.com/articles/s41... and bpspubs.onlinelibrary.wiley.com/doi/10.1111/...

So Yoda1 is the compound that actives Piezo channels and Dooku1 blocks them!!

Piezo channels are ... wait for it ... Force channels
#maythe4thbewithyou
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ukresearch.bsky.social
Research drives discovery at UK.

Funding from the NIH makes a difference. UK Acting Vice President for Research Ilhem Messaoudi explains how this funding impacts Kentuckians.

Learn more: www.research.uky.edu/news/researc...
Reposted by The Tidgewell Research Lab
jeremymberg.bsky.social
Some important additional considerations about the need to comment of the implementation of schedule F.

First, several sources have indicated that Institute Director and Division Director positions would likely be converted but not Program Officers.

1/n
thetidgelab.bsky.social
This is heartbreaking and terrifying
jeremymberg.bsky.social
NIH just posted a Notice with the new Terms and Conditions...

grants.nih.gov/grants/guide...
thetidgelab.bsky.social
Really fun visit to @ucsantacruz.bsky.social for a seminar
Huge thanks to @drlaurasanchez.bsky.social for the invite
Tried my best to channel banana slugs and was rewarded with a couple along the walk in 😁
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ddiamond.bsky.social
See this chart for one stark example: NIH funding has dramatically slowed down.

Grant awards are down *$3 billion* so far, compared to same time period last year

I asked the White House to explain.

“This is not a researcher entitlement program,” said an official, defending their new approach.
thetidgelab.bsky.social
Awesome visit to @utah.edu for a seminar in the Pharm Tox Department
Lots of great neuroscience focused chats and great group of faculty plus snuck out to see a bit of nature as well
thetidgelab.bsky.social
Another fun international collaboration (that started via email) resulting in a publication out today!
Happy to be a small part of this awesome chemistry effort by the groups at Uni Bristol
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planetdr.bsky.social
All of the physics knowledge in the world and all of the paper published about NASA’s success and failures won’t save you if you fired the seamstress who knew the one weird trick to the stitches on a blanket or a parachute.

Not all knowledge is translated well by text. (2/)
thetidgelab.bsky.social
One new post on Federal Register about meetings in late March early April and three more that should be posted by tomorrow ... at least review can return and hopefully that means we can have a sense of grant funding soon