Vincent CASTRIC
@vincentcastric.bsky.social
Evolutionary biologist @CNRS - European citizen 🇪🇺.
Reposted by Vincent CASTRIC
🪱 Selfish genes are everywhere and drive some of biology’s biggest innovations (CRISPR, antibody recombination, epigenetics). Yet almost no one asks the obvious question: how does a selfish gene begin? Our new manuscript uncovers how selfishness can emerge directly from the host genome.
November 24, 2025 at 1:03 PM
🪱 Selfish genes are everywhere and drive some of biology’s biggest innovations (CRISPR, antibody recombination, epigenetics). Yet almost no one asks the obvious question: how does a selfish gene begin? Our new manuscript uncovers how selfishness can emerge directly from the host genome.
Reposted by Vincent CASTRIC
Our new collaborative work led by @taliamycota.bsky.social
Jiajun Cui & Emma Caullireau between my lab @ucllifesciences.bsky.social @cloeucl.bsky.social & the Karasov Lab (tkarasovlab.org) @uofubiology.bsky.social
and collaborators: @plantricia.bsky.social et al.
tinyurl.com/5yx2wmz5
(1/n)
Jiajun Cui & Emma Caullireau between my lab @ucllifesciences.bsky.social @cloeucl.bsky.social & the Karasov Lab (tkarasovlab.org) @uofubiology.bsky.social
and collaborators: @plantricia.bsky.social et al.
tinyurl.com/5yx2wmz5
(1/n)
November 18, 2025 at 8:41 AM
Our new collaborative work led by @taliamycota.bsky.social
Jiajun Cui & Emma Caullireau between my lab @ucllifesciences.bsky.social @cloeucl.bsky.social & the Karasov Lab (tkarasovlab.org) @uofubiology.bsky.social
and collaborators: @plantricia.bsky.social et al.
tinyurl.com/5yx2wmz5
(1/n)
Jiajun Cui & Emma Caullireau between my lab @ucllifesciences.bsky.social @cloeucl.bsky.social & the Karasov Lab (tkarasovlab.org) @uofubiology.bsky.social
and collaborators: @plantricia.bsky.social et al.
tinyurl.com/5yx2wmz5
(1/n)
Reposted by Vincent CASTRIC
We (Nordborg & Weigel labs) need input on the next generation of genome browsers & data download modes for the #Arabidopsis #1001GenomesPlus project. We have now a curated collection of over 500 long read genomes.
Please help us by filling out this questionnaire: docs.google.com/forms/d/e/1F...
Please help us by filling out this questionnaire: docs.google.com/forms/d/e/1F...
Next generation of 1001 Genomes Plus browser and data download
Please indicate all features you would like to see in a browser that displays features of completely sequenced Arabidopsis thaliana genomes
docs.google.com
November 24, 2025 at 2:49 PM
We (Nordborg & Weigel labs) need input on the next generation of genome browsers & data download modes for the #Arabidopsis #1001GenomesPlus project. We have now a curated collection of over 500 long read genomes.
Please help us by filling out this questionnaire: docs.google.com/forms/d/e/1F...
Please help us by filling out this questionnaire: docs.google.com/forms/d/e/1F...
Reposted by Vincent CASTRIC
#OnThisDay in 1859, Charles Darwin's On the Origin of Species was first published.
Much of the original manuscript was used as scrap paper by Darwin's children. On the back of this painting of a house is an original manuscript page from Origin!
#CambridgeUniversityLibrary (DAR 185)
Much of the original manuscript was used as scrap paper by Darwin's children. On the back of this painting of a house is an original manuscript page from Origin!
#CambridgeUniversityLibrary (DAR 185)
November 24, 2025 at 11:26 AM
#OnThisDay in 1859, Charles Darwin's On the Origin of Species was first published.
Much of the original manuscript was used as scrap paper by Darwin's children. On the back of this painting of a house is an original manuscript page from Origin!
#CambridgeUniversityLibrary (DAR 185)
Much of the original manuscript was used as scrap paper by Darwin's children. On the back of this painting of a house is an original manuscript page from Origin!
#CambridgeUniversityLibrary (DAR 185)
Reposted by Vincent CASTRIC
Seeking a postdoc position?
Balancing selection is a fascinating process: malaria resistance, self-incompatibility,etc. Yet, countless examples remain hidden in genomes!
If this question intrigues you, the project led by Laure Segurel and Violaine Llaurens (Paris + Lyon) is perfect! urlr.me/Huj2De
Balancing selection is a fascinating process: malaria resistance, self-incompatibility,etc. Yet, countless examples remain hidden in genomes!
If this question intrigues you, the project led by Laure Segurel and Violaine Llaurens (Paris + Lyon) is perfect! urlr.me/Huj2De
Portail Emploi CNRS - Offre d'emploi - Post-doctoral fellow (M/F): Assessing the power of current methods to detect balancing selection in population genomic datasets
urlr.me
November 18, 2025 at 10:16 AM
Seeking a postdoc position?
Balancing selection is a fascinating process: malaria resistance, self-incompatibility,etc. Yet, countless examples remain hidden in genomes!
If this question intrigues you, the project led by Laure Segurel and Violaine Llaurens (Paris + Lyon) is perfect! urlr.me/Huj2De
Balancing selection is a fascinating process: malaria resistance, self-incompatibility,etc. Yet, countless examples remain hidden in genomes!
If this question intrigues you, the project led by Laure Segurel and Violaine Llaurens (Paris + Lyon) is perfect! urlr.me/Huj2De
Reposted by Vincent CASTRIC
#OpenCloning is a an Open Source alternative to SnapGene/Benchling that supports automation and integration with other software
✅ Free
🔓 Open Source
🧬 More cloning methods than SnapGene
🤖 Can be automated with python
👨🔬 Built by a researcher — for researchers!
👉 Check it out at opencloning.org
✅ Free
🔓 Open Source
🧬 More cloning methods than SnapGene
🤖 Can be automated with python
👨🔬 Built by a researcher — for researchers!
👉 Check it out at opencloning.org
November 24, 2025 at 4:57 PM
#OpenCloning is a an Open Source alternative to SnapGene/Benchling that supports automation and integration with other software
✅ Free
🔓 Open Source
🧬 More cloning methods than SnapGene
🤖 Can be automated with python
👨🔬 Built by a researcher — for researchers!
👉 Check it out at opencloning.org
✅ Free
🔓 Open Source
🧬 More cloning methods than SnapGene
🤖 Can be automated with python
👨🔬 Built by a researcher — for researchers!
👉 Check it out at opencloning.org
Reposted by Vincent CASTRIC
With the 50-year rise of Arabidopsis as the most studied plant, is it time for its downfall?
Let’s investigate it’s history and outlook 🧵
Let’s investigate it’s history and outlook 🧵
November 24, 2025 at 10:36 AM
With the 50-year rise of Arabidopsis as the most studied plant, is it time for its downfall?
Let’s investigate it’s history and outlook 🧵
Let’s investigate it’s history and outlook 🧵
Reposted by Vincent CASTRIC
Can anyone help:
I want to take photos of arabidopsis rosettes everyday as they grow to get growth curves for a lot of ecotypes. Does anyone know of software that can be used to read the label from inside the photo and rename the file with the plant ID and then amend the date to the file name too?
I want to take photos of arabidopsis rosettes everyday as they grow to get growth curves for a lot of ecotypes. Does anyone know of software that can be used to read the label from inside the photo and rename the file with the plant ID and then amend the date to the file name too?
November 21, 2025 at 1:50 PM
Can anyone help:
I want to take photos of arabidopsis rosettes everyday as they grow to get growth curves for a lot of ecotypes. Does anyone know of software that can be used to read the label from inside the photo and rename the file with the plant ID and then amend the date to the file name too?
I want to take photos of arabidopsis rosettes everyday as they grow to get growth curves for a lot of ecotypes. Does anyone know of software that can be used to read the label from inside the photo and rename the file with the plant ID and then amend the date to the file name too?
Reposted by Vincent CASTRIC
Registration for #APSPM2026 closes soon.
Everyone’s welcome! whether you study evolution, structure, or computational methods, join us in Brisbane (and online) Feb 16–18, 2026 to learn how protein structure meets phylogenetics.
biosig.lab.uq.edu.au/strphy26
@official-smbe.bsky.social
Everyone’s welcome! whether you study evolution, structure, or computational methods, join us in Brisbane (and online) Feb 16–18, 2026 to learn how protein structure meets phylogenetics.
biosig.lab.uq.edu.au/strphy26
@official-smbe.bsky.social
November 23, 2025 at 10:03 PM
Registration for #APSPM2026 closes soon.
Everyone’s welcome! whether you study evolution, structure, or computational methods, join us in Brisbane (and online) Feb 16–18, 2026 to learn how protein structure meets phylogenetics.
biosig.lab.uq.edu.au/strphy26
@official-smbe.bsky.social
Everyone’s welcome! whether you study evolution, structure, or computational methods, join us in Brisbane (and online) Feb 16–18, 2026 to learn how protein structure meets phylogenetics.
biosig.lab.uq.edu.au/strphy26
@official-smbe.bsky.social
Reposted by Vincent CASTRIC
It's Friday. This means it is time for a new post on #Autism : The Evidence. If you missed last week, I discussed what is TRULY behind the rise in prevalence. Today I am going to talk about what it is not: #VACCINES . They are SAFE and EFFECTIVE, but where did this idea come from?
November 22, 2025 at 4:35 AM
Reposted by Vincent CASTRIC
I wrote a little bit about the "missing heritability" question and several recent studies that have brought it to a close. A short 🧵
The missing heritability question is now (mostly) answered
Not with a bang but with a whimper
theinfinitesimal.substack.com
November 21, 2025 at 10:34 PM
I wrote a little bit about the "missing heritability" question and several recent studies that have brought it to a close. A short 🧵
Reposted by Vincent CASTRIC
I was quite impressed and humbled yesterday to give a talk at the @linneansociety.bsky.social, in front of this very portrait and plate!
November 21, 2025 at 9:37 PM
I was quite impressed and humbled yesterday to give a talk at the @linneansociety.bsky.social, in front of this very portrait and plate!
Reposted by Vincent CASTRIC
📌 Appel à propositions pour les mini-#symposia à #JOBIM2026
📅 #JOBIM aura lieu à Strasbourg du 30/06 au 3/07/26
ℹ️ Sessions thématiques afin de favoriser les échanges autour de sujets émergents, interdisciplinaires ou particulièrement dynamiques en #bioinformatique et #biologie #computationnelle
📅 #JOBIM aura lieu à Strasbourg du 30/06 au 3/07/26
ℹ️ Sessions thématiques afin de favoriser les échanges autour de sujets émergents, interdisciplinaires ou particulièrement dynamiques en #bioinformatique et #biologie #computationnelle
November 19, 2025 at 7:38 PM
📌 Appel à propositions pour les mini-#symposia à #JOBIM2026
📅 #JOBIM aura lieu à Strasbourg du 30/06 au 3/07/26
ℹ️ Sessions thématiques afin de favoriser les échanges autour de sujets émergents, interdisciplinaires ou particulièrement dynamiques en #bioinformatique et #biologie #computationnelle
📅 #JOBIM aura lieu à Strasbourg du 30/06 au 3/07/26
ℹ️ Sessions thématiques afin de favoriser les échanges autour de sujets émergents, interdisciplinaires ou particulièrement dynamiques en #bioinformatique et #biologie #computationnelle
Reposted by Vincent CASTRIC
Fun week for DNA methylation research! Here is a thread of three cool papers that came out, all with an evolution angle. And a bonus 4th that examines DNAme/PcG interplay (certainly an interest for our lab!) #Epigenetics
November 19, 2025 at 9:48 AM
Fun week for DNA methylation research! Here is a thread of three cool papers that came out, all with an evolution angle. And a bonus 4th that examines DNAme/PcG interplay (certainly an interest for our lab!) #Epigenetics
Reposted by Vincent CASTRIC
I’ve released a tool to sketch and edit phylogenetic trees!
yawak.jp/PhyloWeaver/
Load a Newick file and intuitively add/remove/resize branches.
Useful for quick conceptual trees, extracting subtrees, or turning ideas into Newick.
yawak.jp/PhyloWeaver/
Load a Newick file and intuitively add/remove/resize branches.
Useful for quick conceptual trees, extracting subtrees, or turning ideas into Newick.
PhyloWeaver – Interactive phylogenetic tree editor
Edit and visualize phylogenetic trees directly in your browser. PhyloWeaver lets you interactively rearrange tree topologies and export high-quality figures for publications and presentations.
yawak.jp
November 18, 2025 at 1:59 AM
I’ve released a tool to sketch and edit phylogenetic trees!
yawak.jp/PhyloWeaver/
Load a Newick file and intuitively add/remove/resize branches.
Useful for quick conceptual trees, extracting subtrees, or turning ideas into Newick.
yawak.jp/PhyloWeaver/
Load a Newick file and intuitively add/remove/resize branches.
Useful for quick conceptual trees, extracting subtrees, or turning ideas into Newick.
Reposted by Vincent CASTRIC
gggenomes: A Grammar of Graphics for Comparative Genomics thackl.github.io/gggenomes/ #Rstats
A Grammar of Graphics for Comparative Genomics
An extension of ggplot2 for creating complex genomic maps. It builds on the power of ggplot2 and tidyverse adding new ggplot2-style geoms & positions and dplyr-style verbs to manipulate the…
thackl.github.io
November 18, 2025 at 7:02 PM
gggenomes: A Grammar of Graphics for Comparative Genomics thackl.github.io/gggenomes/ #Rstats
Reposted by Vincent CASTRIC
We are growing our first #Arabidopsis accessions!! Thanks to Nacho and colleagues at CRAG @uab.cat and Sònia @sphaeromeria.bsky.social @ibb-botanic.bsky.social!!
November 18, 2025 at 5:34 PM
We are growing our first #Arabidopsis accessions!! Thanks to Nacho and colleagues at CRAG @uab.cat and Sònia @sphaeromeria.bsky.social @ibb-botanic.bsky.social!!
Reposted by Vincent CASTRIC
Un poste d’IE en bioinformatique est actuellement ouvert au CEFE à Montpellier pour travailler dans le cadre de l'ERC RegEvol.
Détails ici:
emploi.cnrs.fr/Offres/CDD/U...
Début 01/01/2026 pour 18 mois potentiellement renouvelable.
candidature jusqu'au 29/11
N’hésitez pas à diffuser largement
Détails ici:
emploi.cnrs.fr/Offres/CDD/U...
Début 01/01/2026 pour 18 mois potentiellement renouvelable.
candidature jusqu'au 29/11
N’hésitez pas à diffuser largement
Portail Emploi CNRS - Offre d'emploi - Ingénieur d'études en bioinformatique (H/F)
emploi.cnrs.fr
November 18, 2025 at 3:09 PM
Un poste d’IE en bioinformatique est actuellement ouvert au CEFE à Montpellier pour travailler dans le cadre de l'ERC RegEvol.
Détails ici:
emploi.cnrs.fr/Offres/CDD/U...
Début 01/01/2026 pour 18 mois potentiellement renouvelable.
candidature jusqu'au 29/11
N’hésitez pas à diffuser largement
Détails ici:
emploi.cnrs.fr/Offres/CDD/U...
Début 01/01/2026 pour 18 mois potentiellement renouvelable.
candidature jusqu'au 29/11
N’hésitez pas à diffuser largement
Reposted by Vincent CASTRIC
I'm really glad I moved to Canada in 2017.
Most of the time it is very normal to live here.
But then sometimes there is a 5-gallon bucket labeled "SAUCE TRADITIONNELLE | TRADITIONAL SAUCE | poutine Québécoise | 180 litres" in my office.
Most of the time it is very normal to live here.
But then sometimes there is a 5-gallon bucket labeled "SAUCE TRADITIONNELLE | TRADITIONAL SAUCE | poutine Québécoise | 180 litres" in my office.
November 17, 2025 at 5:39 PM
I'm really glad I moved to Canada in 2017.
Most of the time it is very normal to live here.
But then sometimes there is a 5-gallon bucket labeled "SAUCE TRADITIONNELLE | TRADITIONAL SAUCE | poutine Québécoise | 180 litres" in my office.
Most of the time it is very normal to live here.
But then sometimes there is a 5-gallon bucket labeled "SAUCE TRADITIONNELLE | TRADITIONAL SAUCE | poutine Québécoise | 180 litres" in my office.
Reposted by Vincent CASTRIC
November 15, 2025 at 11:57 AM
Reposted by Vincent CASTRIC
Our NY area population genetics meeting is back and "upgraded", as Simons Foundation @simonsfoundation.org generously agreed to host. Please save the date: March 9, 2026. Look forward to seeing many of you from NY and beyond.
SAVE THE DATE: the yearly NY Population Genetics meeting will be back on March 9 2026, generously hosted by the
@simonsfoundation.org. Details to follow. Please RT.
@simonsfoundation.org. Details to follow. Please RT.
November 14, 2025 at 5:58 PM
Our NY area population genetics meeting is back and "upgraded", as Simons Foundation @simonsfoundation.org generously agreed to host. Please save the date: March 9, 2026. Look forward to seeing many of you from NY and beyond.
Reposted by Vincent CASTRIC
🌻 Sharing this preprint where we assembled 3 new chromosome-level genomes, including the first for Asteraceae's South American sister Calyceraceae! Asteraceae uses all the tricks when it comes to being the most ecologically successful family of flowering plants. www.biorxiv.org/content/10.1...
www.biorxiv.org
November 14, 2025 at 5:00 PM
🌻 Sharing this preprint where we assembled 3 new chromosome-level genomes, including the first for Asteraceae's South American sister Calyceraceae! Asteraceae uses all the tricks when it comes to being the most ecologically successful family of flowering plants. www.biorxiv.org/content/10.1...
Reposted by Vincent CASTRIC
Modestly, we decided to review a century's worth of theories of balancing selection :) onlinelibrary.wiley.com/doi/10.1111/...
A century of theories of balancing selection
Traits that affect organismal fitness are often highly genetically variable. This genetic variation is vital for populations to adapt to their environments, but it is also surprising given that natur...
onlinelibrary.wiley.com
November 14, 2025 at 2:31 PM
Modestly, we decided to review a century's worth of theories of balancing selection :) onlinelibrary.wiley.com/doi/10.1111/...
Reposted by Vincent CASTRIC
A handy translation guide for non-academic speakers.
November 13, 2025 at 2:19 PM
A handy translation guide for non-academic speakers.
Reposted by Vincent CASTRIC
🥁Out on @science.org
👉Transposable elements are vectors of recurrent transgenerational epigenetic inheritance
🔗 www.science.org/doi/full/10....
👏Congratulations to @pierrebaduel.bsky.social, Vincent Colot, and all authors and collaborators!
👉Transposable elements are vectors of recurrent transgenerational epigenetic inheritance
🔗 www.science.org/doi/full/10....
👏Congratulations to @pierrebaduel.bsky.social, Vincent Colot, and all authors and collaborators!
November 12, 2025 at 1:40 PM
🥁Out on @science.org
👉Transposable elements are vectors of recurrent transgenerational epigenetic inheritance
🔗 www.science.org/doi/full/10....
👏Congratulations to @pierrebaduel.bsky.social, Vincent Colot, and all authors and collaborators!
👉Transposable elements are vectors of recurrent transgenerational epigenetic inheritance
🔗 www.science.org/doi/full/10....
👏Congratulations to @pierrebaduel.bsky.social, Vincent Colot, and all authors and collaborators!