Maxim Greenberg
@maxvcg.bsky.social
Group leader at Institut Jacques Monod. When I say "epigenetics" what I really mean is "DNA methylation".
www.maximgreenberglab.com
www.maximgreenberglab.com
Reposted by Maxim Greenberg
We wrote a protocol article detailing induction of dormancy in stem cells, embryos, and blastoids. We hope that it is useful to the community. As usual fun to work with @nicolasrivron.bsky.social, Heidar and Dhanur.
January 26, 2026 at 6:55 PM
We wrote a protocol article detailing induction of dormancy in stem cells, embryos, and blastoids. We hope that it is useful to the community. As usual fun to work with @nicolasrivron.bsky.social, Heidar and Dhanur.
Reposted by Maxim Greenberg
💼 Postdoctoral researcher in computational and experimental biology M/F
📍Institut Jacques Monod / @sandraduharcourt.bsky.social 's Lab
📆 April 1st
Apply on the CNRS job portal before February 13th 🔗 emploi.cnrs.fr/Offres/CDD/U...
📍Institut Jacques Monod / @sandraduharcourt.bsky.social 's Lab
📆 April 1st
Apply on the CNRS job portal before February 13th 🔗 emploi.cnrs.fr/Offres/CDD/U...
January 26, 2026 at 1:50 PM
💼 Postdoctoral researcher in computational and experimental biology M/F
📍Institut Jacques Monod / @sandraduharcourt.bsky.social 's Lab
📆 April 1st
Apply on the CNRS job portal before February 13th 🔗 emploi.cnrs.fr/Offres/CDD/U...
📍Institut Jacques Monod / @sandraduharcourt.bsky.social 's Lab
📆 April 1st
Apply on the CNRS job portal before February 13th 🔗 emploi.cnrs.fr/Offres/CDD/U...
Reposted by Maxim Greenberg
stunning work by our neighbors at @fbzt.bsky.social lab
I’m happy to share the main result of my PhD, which you can find on bioRxiv www.biorxiv.org/content/10.6.... If you are interested in learning about a new way to perform DNA-PAINT multiplexing, which we call Combi-PAINT, or if you are interested in the study of mRNA conformation, keep reading! 1/10
January 26, 2026 at 12:15 PM
stunning work by our neighbors at @fbzt.bsky.social lab
I find it a bit overwritten as all *this* is happening, a catastrophic ice storm is bearing down on the eastern half of the US. Send back for edits.
January 25, 2026 at 7:40 AM
I find it a bit overwritten as all *this* is happening, a catastrophic ice storm is bearing down on the eastern half of the US. Send back for edits.
Reposted by Maxim Greenberg
Archaea fans (and the archaeal-curious) — please spread the word and register! Early sign-ups really help us plan, so if you know you’ll come, please register now.
A reminder to sign up for the 2026 EMBO archaeal meeting im Cambridge: meetings.embo.org/event/26-arc.... Registration is open. We are looking forward to hosting you!
Molecular Biology of Archaea: Life Through the Prism of Archaea
In 1977, Woese and colleagues revealed Archaea as a distinct domain of life. Building on this insight, the discovery of Asgard archaea has strengthened the view that many hallmarks of eukaryotic cell…
meetings.embo.org
January 23, 2026 at 8:19 AM
Archaea fans (and the archaeal-curious) — please spread the word and register! Early sign-ups really help us plan, so if you know you’ll come, please register now.
I am back from an absolutely unforgettable visit to Tsinghua University, where I got to see firsthand a hotbed of incredible epigenetics research. I was so spoiled by my incredible hosts (Fan Zhou and his lab), who introduced me to the cultural and culinary wonders of Beijing. 谢谢 🙏
January 22, 2026 at 10:41 AM
I am back from an absolutely unforgettable visit to Tsinghua University, where I got to see firsthand a hotbed of incredible epigenetics research. I was so spoiled by my incredible hosts (Fan Zhou and his lab), who introduced me to the cultural and culinary wonders of Beijing. 谢谢 🙏
Reposted by Maxim Greenberg
📢 Three new #bioRxiv preprints from our team on holocentric chromosomes.
Together, they connect centromere repeat evolution, karyotype dynamics, and meiotic recombination outcomes, revealing how holocentric genomes evolve and function. 🧬👇
Together, they connect centromere repeat evolution, karyotype dynamics, and meiotic recombination outcomes, revealing how holocentric genomes evolve and function. 🧬👇
January 21, 2026 at 2:45 PM
📢 Three new #bioRxiv preprints from our team on holocentric chromosomes.
Together, they connect centromere repeat evolution, karyotype dynamics, and meiotic recombination outcomes, revealing how holocentric genomes evolve and function. 🧬👇
Together, they connect centromere repeat evolution, karyotype dynamics, and meiotic recombination outcomes, revealing how holocentric genomes evolve and function. 🧬👇
Reposted by Maxim Greenberg
⚠️ The final work of two former PhD students Till @tschwammle.bsky.social and Verena @verenamutzel.bsky.social is out!
➡️⬅️ They dissect how memory can arise from antisense transcription using mathematical modelling 💻, genomics 🧬 and synthetic biology ⚒️! link.springer.com/article/10.1...
➡️⬅️ They dissect how memory can arise from antisense transcription using mathematical modelling 💻, genomics 🧬 and synthetic biology ⚒️! link.springer.com/article/10.1...
Antisense transcription can induce expression memory via stable promoter repression - Genome Biology
Background The capacity of cells to retain a memory of previous signals enables acquisition of unique fates and adaptation to their environment. The underlying gene expression memory can arise from mu...
link.springer.com
January 20, 2026 at 11:02 AM
⚠️ The final work of two former PhD students Till @tschwammle.bsky.social and Verena @verenamutzel.bsky.social is out!
➡️⬅️ They dissect how memory can arise from antisense transcription using mathematical modelling 💻, genomics 🧬 and synthetic biology ⚒️! link.springer.com/article/10.1...
➡️⬅️ They dissect how memory can arise from antisense transcription using mathematical modelling 💻, genomics 🧬 and synthetic biology ⚒️! link.springer.com/article/10.1...
Reposted by Maxim Greenberg
Epimutations: raw material for evolution?
Nabeel Ganem & @psarkies.bsky.social explore how epimutations mediating transgenerational epigenetic inheritance compare to DNA sequence mutations w.r.t. influence on drift and natural selection
link.springer.com/article/10.1...
Nabeel Ganem & @psarkies.bsky.social explore how epimutations mediating transgenerational epigenetic inheritance compare to DNA sequence mutations w.r.t. influence on drift and natural selection
link.springer.com/article/10.1...
Epimutations: raw material for evolution? - The EMBO Journal
Epigenetics is fundamental to cell differentiation as it enables cells with identical genomes to adopt distinct fates. Some epigenetic information can also be transmitted between generations, in a pro...
link.springer.com
January 16, 2026 at 10:33 AM
Epimutations: raw material for evolution?
Nabeel Ganem & @psarkies.bsky.social explore how epimutations mediating transgenerational epigenetic inheritance compare to DNA sequence mutations w.r.t. influence on drift and natural selection
link.springer.com/article/10.1...
Nabeel Ganem & @psarkies.bsky.social explore how epimutations mediating transgenerational epigenetic inheritance compare to DNA sequence mutations w.r.t. influence on drift and natural selection
link.springer.com/article/10.1...
Nice work from Shawn Liu's lab @columbiauniversity.bsky.social ! In vivo DNA methylation editing www.nature.com/articles/s41...
Editing DNA methylation in vivo - Nature Communications
Precise editing of DNA methylation has emerged as a promising tool in disease biology but most applications are limited to in vitro systems. Here, we develop two transgenic mouse lines harboring an in...
www.nature.com
January 16, 2026 at 1:39 PM
Nice work from Shawn Liu's lab @columbiauniversity.bsky.social ! In vivo DNA methylation editing www.nature.com/articles/s41...
Reposted by Maxim Greenberg
Sign up date coming quickly!
Come join us in beautiful Roscoff for this Conference Jacques Monod on Developmental regulation: from molecular to ecological niches
May 18-22, 2026 Roscoff, France
Abstract deadline: January 31, 2026
Apply here: cjm.sb-roscoff.fr/en
Come join us in beautiful Roscoff for this Conference Jacques Monod on Developmental regulation: from molecular to ecological niches
May 18-22, 2026 Roscoff, France
Abstract deadline: January 31, 2026
Apply here: cjm.sb-roscoff.fr/en
January 15, 2026 at 10:31 PM
Sign up date coming quickly!
Come join us in beautiful Roscoff for this Conference Jacques Monod on Developmental regulation: from molecular to ecological niches
May 18-22, 2026 Roscoff, France
Abstract deadline: January 31, 2026
Apply here: cjm.sb-roscoff.fr/en
Come join us in beautiful Roscoff for this Conference Jacques Monod on Developmental regulation: from molecular to ecological niches
May 18-22, 2026 Roscoff, France
Abstract deadline: January 31, 2026
Apply here: cjm.sb-roscoff.fr/en
Reposted by Maxim Greenberg
Our work on #RegulatoryTrajectories is out today in Nat. Comms: www.nature.com/articles/s41...
Led by @raquelrouco.bsky.social, this study establishes a new framework to study how enhancer landscapes act sequentially at developmental loci and are silenced to shape gene expression patterns. (1/n)
Led by @raquelrouco.bsky.social, this study establishes a new framework to study how enhancer landscapes act sequentially at developmental loci and are silenced to shape gene expression patterns. (1/n)
Client Challenge
www.nature.com
January 12, 2026 at 11:48 AM
Our work on #RegulatoryTrajectories is out today in Nat. Comms: www.nature.com/articles/s41...
Led by @raquelrouco.bsky.social, this study establishes a new framework to study how enhancer landscapes act sequentially at developmental loci and are silenced to shape gene expression patterns. (1/n)
Led by @raquelrouco.bsky.social, this study establishes a new framework to study how enhancer landscapes act sequentially at developmental loci and are silenced to shape gene expression patterns. (1/n)
Reposted by Maxim Greenberg
Reposted by Maxim Greenberg
I am very happy (and a bit scared) to present to you what we have been working on over the last 4 years. This manuscript is exactly what I dreamt of when I started the lab and I could not be happier and prouder of the outcome!
Evolutionary dynamics of temporal transcription factor series in the insect optic lobe https://www.biorxiv.org/content/10.64898/2026.01.08.698497v1
January 10, 2026 at 9:43 AM
I am very happy (and a bit scared) to present to you what we have been working on over the last 4 years. This manuscript is exactly what I dreamt of when I started the lab and I could not be happier and prouder of the outcome!
Reposted by Maxim Greenberg
International Genome Dynamics course in Institut Curie-Paris (April 8-15), experimental and computational methods in multiomics,with a #TE centered session.
Free registration, until Jan 15th
Don’t miss it!
👉https://training.institut-curie.org/courses/Genome-Dynamics-2026
@institutcurie.bsky.social
Free registration, until Jan 15th
Don’t miss it!
👉https://training.institut-curie.org/courses/Genome-Dynamics-2026
@institutcurie.bsky.social
January 9, 2026 at 10:54 AM
International Genome Dynamics course in Institut Curie-Paris (April 8-15), experimental and computational methods in multiomics,with a #TE centered session.
Free registration, until Jan 15th
Don’t miss it!
👉https://training.institut-curie.org/courses/Genome-Dynamics-2026
@institutcurie.bsky.social
Free registration, until Jan 15th
Don’t miss it!
👉https://training.institut-curie.org/courses/Genome-Dynamics-2026
@institutcurie.bsky.social
"Bluesky is the worst form of social media except for all the others that have been tried" - Winston Churchill
January 8, 2026 at 10:44 PM
"Bluesky is the worst form of social media except for all the others that have been tried" - Winston Churchill
Reposted by Maxim Greenberg
One thing I'd love to see on this platform is a teeny, tiny more self-awareness that this platform (which I use!) is *wildly* unrepresentative of broader popular opinion and concerns.
January 8, 2026 at 9:39 PM
One thing I'd love to see on this platform is a teeny, tiny more self-awareness that this platform (which I use!) is *wildly* unrepresentative of broader popular opinion and concerns.
The site is good for two things: 1) science and 2) liberal infighting 😅
THREAD
The first full year of tracking research on @bsky.app
Hi, we are Altmetric, and we track how research is communicated across the web.
We now have one full calendar year of Bluesky research data and thought we'd have a looksie.
The first full year of tracking research on @bsky.app
Hi, we are Altmetric, and we track how research is communicated across the web.
We now have one full calendar year of Bluesky research data and thought we'd have a looksie.
January 8, 2026 at 5:51 PM
The site is good for two things: 1) science and 2) liberal infighting 😅
Reposted by Maxim Greenberg
The US has some of the world’s best climate scientists (and more of them than anywhere else) & has contributed disproportionately to understanding the climate system. It’s idiotic for the US to withdraw from the UN Framework Convention on Climate Change & the IPCC but it’s on brand for this regime.
Withdrawing the United States from International Organizations, Conventions, and Treaties that Are Contrary to the Interests of the United States
MEMORANDUM FOR THE HEADS OF EXECUTIVE DEPARTMENTS AND AGENCIES By the authority vested in me as President by the Constitution and the laws of the United
www.whitehouse.gov
January 8, 2026 at 8:40 AM
The US has some of the world’s best climate scientists (and more of them than anywhere else) & has contributed disproportionately to understanding the climate system. It’s idiotic for the US to withdraw from the UN Framework Convention on Climate Change & the IPCC but it’s on brand for this regime.
Reposted by Maxim Greenberg
This went under the radar but answers a fundamental question in Epigenetics...
From many hundreds of olfactory receptor genes, each neuron selects expression of only single one (near-randomly). How?
Outstanding work from Mathieu Boulard and colleagues
www.biorxiv.org/content/10.6...
From many hundreds of olfactory receptor genes, each neuron selects expression of only single one (near-randomly). How?
Outstanding work from Mathieu Boulard and colleagues
www.biorxiv.org/content/10.6...
The transcription of a single olfactory receptor per neuron is enforced by epigenetic silencing of their enhancers
The ability to discriminate thousands of odors in our environment requires each olfactory neuron to express a single olfactory receptor from hundreds of available genes. The biochemical mechanism enfo...
www.biorxiv.org
January 5, 2026 at 12:51 PM
This went under the radar but answers a fundamental question in Epigenetics...
From many hundreds of olfactory receptor genes, each neuron selects expression of only single one (near-randomly). How?
Outstanding work from Mathieu Boulard and colleagues
www.biorxiv.org/content/10.6...
From many hundreds of olfactory receptor genes, each neuron selects expression of only single one (near-randomly). How?
Outstanding work from Mathieu Boulard and colleagues
www.biorxiv.org/content/10.6...
Reposted by Maxim Greenberg
Need a bit of escapism? Not exactly Lord of the Rings, but in similar vein:
doi.org/10.1038/s443...
doi.org/10.1038/s443...
Epimutations: raw material for evolution? - The EMBO Journal
Epigenetics is fundamental to cell differentiation as it enables cells with identical genomes to adopt distinct fates. Some epigenetic information can also be transmitted between generations, in a pro...
link.springer.com
January 6, 2026 at 6:33 PM
Need a bit of escapism? Not exactly Lord of the Rings, but in similar vein:
doi.org/10.1038/s443...
doi.org/10.1038/s443...
Reposted by Maxim Greenberg
Happy to begin the year with the publication of a Journal Club article - Programmed ‘DNA splicing’ removes transposons from genes.
rdcu.be/eXBym
rdcu.be/eXBym
Programmed ‘DNA splicing’ removes transposons from genes
Nature Reviews Molecular Cell Biology - A study that showed that programmed DNA elimination in somatic genomes of ciliates involves excision of intrusive, transposon-derived sequences from genes.
rdcu.be
January 5, 2026 at 2:07 PM
Happy to begin the year with the publication of a Journal Club article - Programmed ‘DNA splicing’ removes transposons from genes.
rdcu.be/eXBym
rdcu.be/eXBym