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Yasu Okamoto

@yasuokamoto.bsky.social

120 followers 150 following 9 posts

Chemist working on Artificial metalloenzyme, Bioinorganic chemistry, Protein engineering. Institute for Molecular Science🇯🇵<-Tohoku Univ.🇯🇵<- Univ. Basel🇨🇭<-Osaka Univ.🇯🇵(Univ. Texas🇺🇸) HP: https://sites.google.com/view/y-okamoto-chemistry/home

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Yasu Okamoto @yasuokamoto.bsky.social · Aug 1

Our latest paper is finally published in @natcomms.nature.com (doi.org/10.1038/s414...) !! We successfully constructed synthetic multinuclear metal complexes using only proteins.

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Reposted by Yasu Okamoto

European Research Council (ERC) @erc.europa.eu · Sep 4

📣 The ERC Starting Grant call results are out!

Find out which early-career researchers will receive funding this year, what they will be investigating, where they will be based... plus lots of other #ERCStG facts & figures for 2025!

➡️ buff.ly/IsafuFh

#FrontierResearch 🇪🇺#EUfunded #HorizonEurope

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Reposted by Yasu Okamoto

Oliver Wenger @wengeroliver.bsky.social · Aug 27

New molecular design absorbs 2 photons to store 2 positive and 2 negative charges

100 ns lifetime, 3 eV energy storage, and 37% quantum yield

A step toward multi-electron photochemistry

Mathis Brändlin and @bjoernpfund.bsky.social in @natchem.nature.com

www.nature.com/articles/s41...

Photoinduced double charge accumulation in a molecular compound - Nature Chemistry

The photoinduced accumulation of redox equivalents is a challenging requirement for artificial photosynthesis. Now a molecule has been developed in which the sequential absorption of photons results i...

www.nature.com

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Yasu Okamoto @yasuokamoto.bsky.social · Aug 1

This is my second original artificial enzyme since going independent! Now I have both synthetic molecule-based (ACS Catal 2023) and metal ion-based ones. Ready for the new journey with them!

Yasu Okamoto @yasuokamoto.bsky.social · Aug 1

Our latest paper is finally published in @natcomms.nature.com (doi.org/10.1038/s414...) !! We successfully constructed synthetic multinuclear metal complexes using only proteins.

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Reposted by Yasu Okamoto

Shinya Tsukiji @shinyatsukiji.bsky.social · Jul 29

Excited to share that our Concept article on the chemogenetic protein translocation tool "SLIPT-PM" is now out in ChemBioChem! We review its development, key features, current applications, and future challenges in chemical biology.
chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...

chemistry-europe.onlinelibrary.wiley.com

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Yasu Okamoto @yasuokamoto.bsky.social · Jul 27

Heading to Long Beach for #ICBIC21! Excited to present our latest artificial metalloenzyme.

Reposted by Yasu Okamoto

Virtual ChemBioTalks @chembiotalks.bsky.social · Jul 24

The fourth talk of the 5th Virtual ChemBioTalks will be given by @cathleenzeymer.bsky.social. She will talk about her group’s exciting research under the title “Design and directed evolution of artificial photoenzymes”.

Make sure to register for free: https://cvent.me/G1geWW

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Reposted by Yasu Okamoto

Ryosuke Kojima @ryosukekojima.bsky.social · Jul 24

Excited to share that our new paper is out in
@jacs.acspublications.org !
We introduce a new design principle for fluorogenic antigen probes, using an intramolecular reaction between a thiol-reactive fluorophore and a cysteine engineered into a DARPin.
pubs.acs.org/doi/10.1021/...

Design of Antigen-Targeting Fluorogenic Probes Utilizing Intramolecular Addition Reaction of Protein-Dye Hybrids

Fluorogenic probes for antigens are useful for various purposes, including medical diagnostics and imaging, but achieving a rapid, large fluorescence increase is difficult. Here, we report a new class...

pubs.acs.org

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Reposted by Yasu Okamoto

Alicia Casitas @aliciacasitas.bsky.social · Jul 20

JOB ALERT! 🚨 Are you interested in organic synthesis and catalysis? We have an open PhD position in our group at Philipps-Universität Marburg in Germany. 👩‍🔬👨‍🔬 Deadline: 10th August 2025. For more details and to submit an application, please refer to the official posting here: lnkd.in/e_f3Xerq
#chemsky

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Reposted by Yasu Okamoto

Oliver Wenger @wengeroliver.bsky.social · Jul 18

We show how photoredox catalysis can bypass Kasha’s rule, enabling reactions from higher excited states.

This work, led by the exceptional @bjoernpfund.bsky.social, offers new insights into photochemical reactivity.

Published in JACS @jacs.acspublications.org

bit.ly/3IysmjX

Breaking Kasha’s Rule to Enable Higher Reactivity in Photoredox Catalysis

Nearly all photochemical transformations known to date follow Kasha’s rule, implying that reactions occur only from the lowest electronically excited state of a given spin multiplicity due to the fast...

bit.ly

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Reposted by Yasu Okamoto

Kai Johnsson @kjohnsson.bsky.social · Jul 10

Molecular recording of cellular protein kinase activity with chemical labeling:

www.nature.com/articles/s41...

Congratulations to De-en Sun and the entire team.

Molecular recording of cellular protein kinase activity with chemical labeling - Nature Chemical Biology

Molecular recorders based on kinase activity-dependent protein labeling track specific kinase activities to understand their link to cellular phenotypes in heterogeneous cell populations and in vivo.

www.nature.com

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Yasu Okamoto @yasuokamoto.bsky.social · Jul 7

Grateful for the opportunity to present our photo-driven artificial metalloenzyme at #Biotrans2025. It was wonderful to reconnect with old colleagues and meet new friends!

Yasu Okamoto @yasuokamoto.bsky.social · Jul 7

So many impressive and inspiring presentations at Repartzyme! Amazing to see how rapidly and significantly the field is progressing. Thrilled to meet many of my scientific heroes from my undergraduate days.

Yasu Okamoto @yasuokamoto.bsky.social · Jun 29

Very happy to be back in Basel🇨🇭 for a while!

Reposted by Yasu Okamoto

University of Basel @unibas.ch · Jun 17

Professor Oliver Wenger has received an Advanced Grant for his research projects in photochemistry, which involve chemical reactions triggered by light. This plays a part in processes such as the conversion of solar energy into other forms of energy.
@wengeroliver.bsky.social

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Reposted by Yasu Okamoto

University of Basel @unibas.ch · Jun 17

Professor Thomas Ward's ERC project "Bionix" explores new ways of producing nitrate, which plays a key role in global agriculture as a plant nutrient in fertilizers. Professor Ward and his team aim to establish an efficient process that uses significantly less energy and produces fewer emissions.

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Reposted by Yasu Okamoto

Verena Resch | 🧪🖥️ @verenaresch.bsky.social · Feb 18

New cover design @naturesynthesis.bsky.social

I really had fun visualizing the Turner Lab’s research and am grateful that they let me take a playful approach. We turned one-pot multienzyme cascade reactions into a marble run—perfect for an animated cover!
Research behind the cover ▶️ rdcu.be/ealKn

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Reposted by Yasu Okamoto

Johannes Rebelein @rebeleinlab.bsky.social · Jan 25

Come and join us in Marburg

Max Planck Institute for Terrestrial Microbiology @mpimicrobiomarburg.bsky.social · Jan 20

Exciting opportunity! Max Planck Institute for Terrestrial Microbiology is looking for a Head of the DNA-Biofoundry MaxGENESYS. Join us in vibrant #Marburg - apply by 15 February 2025. #ScienceJobs #SyntheticBiology #Biofoundry @maxplanck.de

Job opening for the Head of the Max Planck DNA Biofoundry for automated DNA assembly. Applications are invited for a full time scientist position to head a Core Facility for DNA assembly / DNA Biofoundry at the Max Planck Institute (MPI) for Terrestrial Microbiology in Marburg, Germany (http://www.mpi-marburg.mpg.de). Further information can be obtained from https://www.mpi-marburg.mpg.de/148510/e_open_positions.

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Reposted by Yasu Okamoto

Ryosuke Kojima @ryosukekojima.bsky.social · Jan 21

当グループ(@東大医)で博士研究員を募集しています。細胞外小胞/細胞間コミュニケーションの理解や操作を可能とする合成生物学研究に興味のある方はぜひご検討ください。もちろん学振PDの応募などの相談にものれます。ご興味があればお気軽にDMください！https://www.m.u-tokyo.ac.jp/news/jobs/20250121.pdf

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Reposted by Yasu Okamoto

Chemjobber @chemjobber.bsky.social · Jan 14

The 2025 Chemistry Faculty Jobs List has 462 tenure-track positions and 77 teaching positions: bit.ly/facultychemj... #facultychemjobs chemjobs chemsky

The 2025 Chemistry Faculty Jobs List

bit.ly

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Reposted by Yasu Okamoto

Xile Hu @xilehu-epfl.bsky.social · Jan 7

By incorporating two cofactors into the four binding sites of streptavidin, we engineered programmable artifical enzymes for tandem abiotic transformations including an enantioselective formal C–H hydroxylation and a photooxidation-Michael addition. onlinelibrary.wiley.com/doi/10.1002/... #chemsky

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Yasu Okamoto @yasuokamoto.bsky.social · Dec 13

📣 Our website got a fresh makeover! 🔍 Check out our updated lab website!
sites.google.com/view/y-okamo...

Designer Biomolecular Chemistry - English

Member Staff Assoc. Prof. (PI) : Yasunori Okamoto Assist. Prof. : – Administrative assistant : Ayaka Noda Research assistant : Tomoko Etoh Student It's you. Apply now！

sites.google.com

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The Royal Swedish Academy of Sciences @scienceacademyswe.bsky.social · Dec 5

Today, several #NobelPrize Laureates arrive in Stockholm, warmly welcomed by Hans Ellegren. Here we see David Baker stepping off the plane at Arlanda.

This week is packed with inspiration, press conferences and lectures, so stay tuned! 🌟
@uofwa.bsky.social @hhmi.bsky.social
#Science #AcademicSky

Hans Ellegren Welcoming David Baker at Stockholm Arlanda.

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Reposted by Yasu Okamoto

Eric Topol @erictopol.bsky.social · Dec 5

The next frontier of T cell therapeutics when the T also stands for tissue-targeting, such as brain or local immune response, via synthetic gene circuits
@science.org

science.org/doi/10.1126/...
science.org/doi/10.1126/...
science.org/doi/10.1126/...

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Reposted by Yasu Okamoto

Anna Peacock - Peacock Group @peacockgroup.bsky.social · Dec 5

One more week till the deadline - Please reach out if you have any questions or want to know more. Thanks

Anna Peacock - Peacock Group @peacockgroup.bsky.social · Nov 21

We're recruiting two PDRAs (one computational and one experimental) to join the project "Designer metallo coiled coils for use in MRI" - closing date Dec.12th. Please get in touch if you'd like to know more. @uobchemistry.bsky.social
www.jobs.ac.uk/job/DKS611/r...
www.jobs.ac.uk/job/DKS605/r...

Research Fellow at University of Birmingham

Looking for a new job opportunity in academia? Check out this job opening for a Research Fellow on jobs.ac.uk!

www.jobs.ac.uk

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