Saccharomyces Genome Database
@yeastgenome.bsky.social
The Saccharomyces Genome Database (SGD) provides comprehensive biological information for the budding yeast Saccharomyces cerevisiae along with search and analysis tools to explore these data, enabling scientific discovery.
Reposted by Saccharomyces Genome Database
The European Drosophila Society #flyEDS extends the condolences on the passing of Antonio García-Bellido, considered the founder of the Spanish school of #Drosophila genetics and an influential figure in developmental biology research worldwide. May he rest in peace.
November 11, 2025 at 2:15 PM
The European Drosophila Society #flyEDS extends the condolences on the passing of Antonio García-Bellido, considered the founder of the Spanish school of #Drosophila genetics and an influential figure in developmental biology research worldwide. May he rest in peace.
Using #yeast, Yu et al show templated insertions at double-strand breaks in cancers arise from foldback mechanism involving microhomologies. Lack of RPA may drive this process, shedding light on cancer's genetic instability #CancerResearch #Genetics #DNARepair
www.yeastgenome.org/reference/39...
www.yeastgenome.org/reference/39...
November 13, 2025 at 8:57 PM
Using #yeast, Yu et al show templated insertions at double-strand breaks in cancers arise from foldback mechanism involving microhomologies. Lack of RPA may drive this process, shedding light on cancer's genetic instability #CancerResearch #Genetics #DNARepair
www.yeastgenome.org/reference/39...
www.yeastgenome.org/reference/39...
New insights into #meiosisI reveal distinct roles of spindle checkpoint proteins. Mad2p drives transition to #metaphase, Mad3p ensures microtubule-dependent #chromosome capture on spindle, safeguarding fidelity of segregation #Yeast #CellBiology #Genetics www.yeastgenome.org/reference/39...
November 12, 2025 at 10:57 PM
New insights into #meiosisI reveal distinct roles of spindle checkpoint proteins. Mad2p drives transition to #metaphase, Mad3p ensures microtubule-dependent #chromosome capture on spindle, safeguarding fidelity of segregation #Yeast #CellBiology #Genetics www.yeastgenome.org/reference/39...
Researchers have identified cullin E3 ubiquitin ligase Rtt101p as key player in repairing DNA−protein crosslinks (DPCs) during #DNA #replication. Rtt101p's role is crucial across #cellCycle phases, ensuring genomic integrity. #Yeast #Genetics #CellBiology www.yeastgenome.org/reference/39...
November 12, 2025 at 10:16 PM
Researchers have identified cullin E3 ubiquitin ligase Rtt101p as key player in repairing DNA−protein crosslinks (DPCs) during #DNA #replication. Rtt101p's role is crucial across #cellCycle phases, ensuring genomic integrity. #Yeast #Genetics #CellBiology www.yeastgenome.org/reference/39...
Reposted by Saccharomyces Genome Database
This October I’m drawing 1 molecule a day inspired by proteins in pdb @rcsbpdb.bsky.social
Day 13
Prompt DRINK
Pdb: 7BTW
A pair of mitochondrial outer membrane β-barrel SAM complexes from Saccharomyces cerevisiae, the yeast used to make beer.
Cheers!
Next: TRUNK
Suggestions?
Day 13
Prompt DRINK
Pdb: 7BTW
A pair of mitochondrial outer membrane β-barrel SAM complexes from Saccharomyces cerevisiae, the yeast used to make beer.
Cheers!
Next: TRUNK
Suggestions?
October 14, 2025 at 5:57 AM
This October I’m drawing 1 molecule a day inspired by proteins in pdb @rcsbpdb.bsky.social
Day 13
Prompt DRINK
Pdb: 7BTW
A pair of mitochondrial outer membrane β-barrel SAM complexes from Saccharomyces cerevisiae, the yeast used to make beer.
Cheers!
Next: TRUNK
Suggestions?
Day 13
Prompt DRINK
Pdb: 7BTW
A pair of mitochondrial outer membrane β-barrel SAM complexes from Saccharomyces cerevisiae, the yeast used to make beer.
Cheers!
Next: TRUNK
Suggestions?
Reposted by Saccharomyces Genome Database
In the latest #Yeast research article, Miguel A. Rocha, Gowda Bhavani and Jacob Fleischmann investigate the role of exonuclease-resistant ribosomal RNAs in Saccharomyces cerevisiae, their relationship with nutritional status and the TOR signalling pathway.
onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com/doi/10.1002/...
18S and 25S Exonuclease Resistant Ribosomal RNA Molecules Are Produced by 5′‐End Modification During TOR Inhibition.
Saccharomyces cerevisiae produces exonuclease-resistant rRNA molecules upon TOR inhibition. This phenomenon occurs when cells enter the diauxic phase, upon addition of rapamycin to the culture, or wh...
onlinelibrary.wiley.com
November 10, 2025 at 2:10 PM
In the latest #Yeast research article, Miguel A. Rocha, Gowda Bhavani and Jacob Fleischmann investigate the role of exonuclease-resistant ribosomal RNAs in Saccharomyces cerevisiae, their relationship with nutritional status and the TOR signalling pathway.
onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com/doi/10.1002/...
Unlocking secrets of #meiosis! Wei et al. reveal how Mei5-Sae3 complex enhances Dmc1p assembly by stabilizing Dmc1p clusters on ssDNA, altering RPA dynamics, paving way for successful interhomolog recombination. Fascinating proteins in action! #yeast #Genetics www.yeastgenome.org/reference/39...
November 7, 2025 at 11:45 PM
Unlocking secrets of #meiosis! Wei et al. reveal how Mei5-Sae3 complex enhances Dmc1p assembly by stabilizing Dmc1p clusters on ssDNA, altering RPA dynamics, paving way for successful interhomolog recombination. Fascinating proteins in action! #yeast #Genetics www.yeastgenome.org/reference/39...
Insights into mitochondrial #ribosome reveal mL44 mutations linked to childhood #cardiomyopathy, neuro issues. Box et al. study #yeast homolog MRPL3, show evolutionary divergence, translation hierarchy in mitochondrial protein synthesis #Mitochondria #Genetics www.yeastgenome.org/reference/38...
November 7, 2025 at 11:14 PM
Insights into mitochondrial #ribosome reveal mL44 mutations linked to childhood #cardiomyopathy, neuro issues. Box et al. study #yeast homolog MRPL3, show evolutionary divergence, translation hierarchy in mitochondrial protein synthesis #Mitochondria #Genetics www.yeastgenome.org/reference/38...
Cap-binding protein eIF4E links protein synthesis to metabolic regulation. When depleted, cells adapt by upregulating amino acid catabolism and biosynthesis. Read how this regulation helps maintain balance during stress. #CellBiology #ProteinSynthesis #yeast www.yeastgenome.org/reference/38...
November 7, 2025 at 5:18 PM
Cap-binding protein eIF4E links protein synthesis to metabolic regulation. When depleted, cells adapt by upregulating amino acid catabolism and biosynthesis. Read how this regulation helps maintain balance during stress. #CellBiology #ProteinSynthesis #yeast www.yeastgenome.org/reference/38...
2026 #Yeast #Genetics Meeting is 13–17 June 2026 in Pacific Grove CA. Conference website has invited speakers, abstract submission topics, preliminary schedule, etc. Bookmark the site as additional updates will be published as they become available. #YEAST26
genetics-gsa.org/yeast-2026/
genetics-gsa.org/yeast-2026/
November 7, 2025 at 3:41 PM
2026 #Yeast #Genetics Meeting is 13–17 June 2026 in Pacific Grove CA. Conference website has invited speakers, abstract submission topics, preliminary schedule, etc. Bookmark the site as additional updates will be published as they become available. #YEAST26
genetics-gsa.org/yeast-2026/
genetics-gsa.org/yeast-2026/
The 33rd Fungal Genetics Conference is accepting abstracts - due December 4, 2025! genetics-gsa.org/fungal-2026/... #FUNGAL26
November 4, 2025 at 10:05 PM
The 33rd Fungal Genetics Conference is accepting abstracts - due December 4, 2025! genetics-gsa.org/fungal-2026/... #FUNGAL26
Reposted by Saccharomyces Genome Database
📣Advance your skills in #pathogen genomics — no coding required — with the #Fungal Pathogen Genomics (Virtual) course #FungiDB @ensembl.org #mycocsm @yeastgenome.bsky.social #CGD
🗓️ 1–5 June 2026 Deadline: 16 March 2026
Apply here: coursesandconferences.wellcomeconnectingscience.org/event/fungal...
🗓️ 1–5 June 2026 Deadline: 16 March 2026
Apply here: coursesandconferences.wellcomeconnectingscience.org/event/fungal...
October 29, 2025 at 2:43 PM
📣Advance your skills in #pathogen genomics — no coding required — with the #Fungal Pathogen Genomics (Virtual) course #FungiDB @ensembl.org #mycocsm @yeastgenome.bsky.social #CGD
🗓️ 1–5 June 2026 Deadline: 16 March 2026
Apply here: coursesandconferences.wellcomeconnectingscience.org/event/fungal...
🗓️ 1–5 June 2026 Deadline: 16 March 2026
Apply here: coursesandconferences.wellcomeconnectingscience.org/event/fungal...
Abstract submission and registration now open for the 33rd #Fungal #Genetics Conference at #Asilomar! Abstracts due December 4, early registration deadline December 5.
genetics-gsa.org/fungal-2026/
genetics-gsa.org/fungal-2026/
October 24, 2025 at 9:58 PM
Abstract submission and registration now open for the 33rd #Fungal #Genetics Conference at #Asilomar! Abstracts due December 4, early registration deadline December 5.
genetics-gsa.org/fungal-2026/
genetics-gsa.org/fungal-2026/
Reposted by Saccharomyces Genome Database
Nature has published an article on the crisis facing MODs
Model organism databases face budget cuts and closures www.nature.com/articles/d41...
@zfinmod.bsky.social @xenbase.bsky.social @yeastgenome.bsky.social @mousegenome.bsky.social @ratgenome.bsky.social @geneontology.bsky.social @nature.com
Model organism databases face budget cuts and closures www.nature.com/articles/d41...
@zfinmod.bsky.social @xenbase.bsky.social @yeastgenome.bsky.social @mousegenome.bsky.social @ratgenome.bsky.social @geneontology.bsky.social @nature.com
Model organism databases face budget cuts and closures
Beyond the crucial data they contain, these digital archives have provided an important space for academic communities to exchange ideas and resources.
www.nature.com
October 3, 2025 at 6:52 PM
Nature has published an article on the crisis facing MODs
Model organism databases face budget cuts and closures www.nature.com/articles/d41...
@zfinmod.bsky.social @xenbase.bsky.social @yeastgenome.bsky.social @mousegenome.bsky.social @ratgenome.bsky.social @geneontology.bsky.social @nature.com
Model organism databases face budget cuts and closures www.nature.com/articles/d41...
@zfinmod.bsky.social @xenbase.bsky.social @yeastgenome.bsky.social @mousegenome.bsky.social @ratgenome.bsky.social @geneontology.bsky.social @nature.com
Pro tip for getting your data into SGD and other knowledgebases: don't hide the data in the supplemental info in PDF format. Put it in Excel with stable identifiers like SGDIDs and systematic_names (ex. YFL039C) in addition to gene names. #yeast #modelOrganism #getYourDataOutGetCited
August 20, 2025 at 3:17 PM
Pro tip for getting your data into SGD and other knowledgebases: don't hide the data in the supplemental info in PDF format. Put it in Excel with stable identifiers like SGDIDs and systematic_names (ex. YFL039C) in addition to gene names. #yeast #modelOrganism #getYourDataOutGetCited
Latest #yeast #microPublication: Schiemann et al. Functional Analysis of the Yeast Counterpart to the Human GCN2 p.Glu738_Asp739insArgArg Variant
www.micropublication.org/journals/bio... @micropub7n.bsky.social
www.micropublication.org/journals/bio... @micropub7n.bsky.social
August 12, 2025 at 7:27 PM
Latest #yeast #microPublication: Schiemann et al. Functional Analysis of the Yeast Counterpart to the Human GCN2 p.Glu738_Asp739insArgArg Variant
www.micropublication.org/journals/bio... @micropub7n.bsky.social
www.micropublication.org/journals/bio... @micropub7n.bsky.social
WormBase announces its final major update, WS298, will be in Oct2025. No more new WormBase releases; existing data will be moved into Alliance of Genome Resources, ensuring vital C. elegans datasets remain accessible. Stay tuned for more updates.
Read more: blog.wormbase.org/2025/07/23/a...
Read more: blog.wormbase.org/2025/07/23/a...
July 31, 2025 at 9:21 PM
WormBase announces its final major update, WS298, will be in Oct2025. No more new WormBase releases; existing data will be moved into Alliance of Genome Resources, ensuring vital C. elegans datasets remain accessible. Stay tuned for more updates.
Read more: blog.wormbase.org/2025/07/23/a...
Read more: blog.wormbase.org/2025/07/23/a...
#YeastNomenclature reminder: Protein Name Format
#Yeast proteins are referred to by the relevant gene symbol, non-italic, initial letter uppercase and with the suffix ‘p’ (for example, Ade5p). The suffix can be omitted if the word 'protein' is appended (for example, the Ade5 protein).
#Yeast proteins are referred to by the relevant gene symbol, non-italic, initial letter uppercase and with the suffix ‘p’ (for example, Ade5p). The suffix can be omitted if the word 'protein' is appended (for example, the Ade5 protein).
June 26, 2025 at 6:57 PM
#YeastNomenclature reminder: Protein Name Format
#Yeast proteins are referred to by the relevant gene symbol, non-italic, initial letter uppercase and with the suffix ‘p’ (for example, Ade5p). The suffix can be omitted if the word 'protein' is appended (for example, the Ade5 protein).
#Yeast proteins are referred to by the relevant gene symbol, non-italic, initial letter uppercase and with the suffix ‘p’ (for example, Ade5p). The suffix can be omitted if the word 'protein' is appended (for example, the Ade5 protein).
Reposted by Saccharomyces Genome Database
On 16 June, a federal court in Boston will hear two cases challenging the terminations of hundreds of National Institutes of Health grants.
Trump’s cuts to more than 1700 NIH grants get court hearing
District judge could declare terminations unlawful—or toss suit based on technicalities
scim.ag
June 13, 2025 at 4:23 PM
On 16 June, a federal court in Boston will hear two cases challenging the terminations of hundreds of National Institutes of Health grants.
FlyBase needs your help!
Because of recent changes to government funding, the NIH grant that supported FlyBase has been "terminated." flybase.org
Because of recent changes to government funding, the NIH grant that supported FlyBase has been "terminated." flybase.org
June 9, 2025 at 2:42 PM
FlyBase needs your help!
Because of recent changes to government funding, the NIH grant that supported FlyBase has been "terminated." flybase.org
Because of recent changes to government funding, the NIH grant that supported FlyBase has been "terminated." flybase.org
Noticing slowness on the SGD website? Thank the web-scraping AI bots
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Web-scraping AI bots cause disruption for scientific databases and journals
Automated programs gathering training data for artificial-intelligence tools are overwhelming academic websites.
www.nature.com
June 5, 2025 at 3:19 PM
Noticing slowness on the SGD website? Thank the web-scraping AI bots
www.nature.com/articles/d41...
www.nature.com/articles/d41...
#YeastJob: 2-year postdoc available at #Sorbonne Université (central Paris) to investigate dynamic architecture of natural polyploid genomes in #Saccharomyces cerevisiae focusing on resolving complex genomic structure of polyploids at population level.
More info docs.google.com/document/d/1...
More info docs.google.com/document/d/1...
Postdoc_Evol_Genomics_Sorbonne.docx
Postdoctoral position in Yeast Evolutionary Genomics Hosting unit Laboratory of Computational, Quantitative, and Synthetic Biology (CQSB). The CQSB is an interdisciplinary research unit within the ...
docs.google.com
May 19, 2025 at 5:57 PM
#YeastJob: 2-year postdoc available at #Sorbonne Université (central Paris) to investigate dynamic architecture of natural polyploid genomes in #Saccharomyces cerevisiae focusing on resolving complex genomic structure of polyploids at population level.
More info docs.google.com/document/d/1...
More info docs.google.com/document/d/1...
Virtual #Conference: 5th Annual CanFunNet #Fungal #Biology
August 6-8 "From Local to Global"
canfunnet.conferences.uwo.ca
Abstract submissions, early registration open until May30
Topics include: Evolutionary Pathways of Fungal Pathogens, Fungal Genomics, Host Interactions, Fungal Resilience
August 6-8 "From Local to Global"
canfunnet.conferences.uwo.ca
Abstract submissions, early registration open until May30
Topics include: Evolutionary Pathways of Fungal Pathogens, Fungal Genomics, Host Interactions, Fungal Resilience
May 7, 2025 at 4:17 PM
Virtual #Conference: 5th Annual CanFunNet #Fungal #Biology
August 6-8 "From Local to Global"
canfunnet.conferences.uwo.ca
Abstract submissions, early registration open until May30
Topics include: Evolutionary Pathways of Fungal Pathogens, Fungal Genomics, Host Interactions, Fungal Resilience
August 6-8 "From Local to Global"
canfunnet.conferences.uwo.ca
Abstract submissions, early registration open until May30
Topics include: Evolutionary Pathways of Fungal Pathogens, Fungal Genomics, Host Interactions, Fungal Resilience
SGD Newsletter is out!
www.yeastgenome.org/blog/sgd-new...
- SGD’s Latest #GENETICS Publication
- #Pathway Annotations Available as GO Annotations
- New #Yeast #Phenome Links
- #microPublications – Latest Yeast Papers
- Alliance of #Genome Resources – Release 8.1.0
- Upcoming Conferences & Courses
www.yeastgenome.org/blog/sgd-new...
- SGD’s Latest #GENETICS Publication
- #Pathway Annotations Available as GO Annotations
- New #Yeast #Phenome Links
- #microPublications – Latest Yeast Papers
- Alliance of #Genome Resources – Release 8.1.0
- Upcoming Conferences & Courses
SGD Newsletter, Spring 2025 | SGD
The Saccharomyces Genome Database (SGD) provides comprehensive integrated biological information for the budding yeast Saccharomyces cerevisiae.
www.yeastgenome.org
May 2, 2025 at 9:48 PM
SGD Newsletter is out!
www.yeastgenome.org/blog/sgd-new...
- SGD’s Latest #GENETICS Publication
- #Pathway Annotations Available as GO Annotations
- New #Yeast #Phenome Links
- #microPublications – Latest Yeast Papers
- Alliance of #Genome Resources – Release 8.1.0
- Upcoming Conferences & Courses
www.yeastgenome.org/blog/sgd-new...
- SGD’s Latest #GENETICS Publication
- #Pathway Annotations Available as GO Annotations
- New #Yeast #Phenome Links
- #microPublications – Latest Yeast Papers
- Alliance of #Genome Resources – Release 8.1.0
- Upcoming Conferences & Courses