Yiğitcan Sümbelli
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ysumbelli.bsky.social
Yiğitcan Sümbelli
@ysumbelli.bsky.social
Combining 3D biofabrication with synthetic biology via artificial cells | Biomed Eng PhD Candidate

TU Eindhoven | van Hest Lab | The Research Center for Materials Driven Regeneration
Our latest paper is out! We froze complex multiphases in time to study them in coacervates! Check it out here:
doi.org/10.1002/advs...
Preservation of Complex Multiphase Architectures in Polymer‐Based Artificial Cells by Photo‐Crosslinking
Phase separation organizes cellular components, yet stabilizing such dynamic structures in artificial cells remains challenging. A photo-crosslinking approach is presented that prolongs the lifetime ....
doi.org
November 22, 2025 at 8:04 AM
Reposted by Yiğitcan Sümbelli
"If you publish your book now, in the teeth of my opposition, history will condemn you”

“the tone used to describe Rosalind's work in the Epilogue
is perfectly reasonable,
but contrasts ludicrously with
the descriptions of her
in the text itself.”

-Francis Crick

Letter criticizing Watson’s book 🧪
November 8, 2025 at 12:04 AM
Check out our latest paper! We not only prepared artificial cells but also 3D printed artificial organelles inside of them.

This is one of my favorite projects from my PhD, and I am so happy that I can share the published version now.

pubs.acs.org/doi/10.1021/...
Intracompartmental 3D Printing of Enzymatically Active Organelle Mimics
Introducing subcellular structures in artificial cells is a key step in mimicking the structure and role of organelles, which are instrumental in compartmentalizing cellular reaction networks. Despite...
pubs.acs.org
November 6, 2025 at 8:44 PM
Getting an email in the early morning, saying that they accept your manuscript for publication is one of the greatest ways to start your day! 🥳
October 31, 2025 at 7:41 AM
The results of brain drain couldn't be more clear. One country's loss is another's win.

www.nature.com/articles/d41...
More than 30% of this century’s science Nobel prizewinners immigrated: see their journeys
The most common destination for eventual Nobel laureates in physics, chemistry and medicine since 2000 is the United States, Nature has found.
www.nature.com
October 11, 2025 at 9:24 AM
Reposted by Yiğitcan Sümbelli
The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi for their groundbreaking discoveries concerning peripheral immune tolerance that prevents the immune system from harming the body 🧪 www.nobelprize.org/prizes/medic...
October 6, 2025 at 9:42 AM
Yingtong just published a very nice article, and I contributed to that with SEM micrographs! In the paper, he introduced a strategy to optimize the optical absorbance of organic photothermal agents (OPTA) by adjusting the morphology of polymer assemblies.
Check it out here:
doi.org/10.1021/jacs...
Solvent-Induced Morphology Control of Polymer Assemblies with Improved Photothermal Features
Organic photothermal agents (OPTAs) are extensively utilized in applications such as therapy and imaging. However, enhancing their photothermal performance often depends on complex molecular designs, ...
doi.org
July 23, 2025 at 11:25 AM
Ah well... I only post academic stuff but the passing of Ozzy Osbourne is significant enough to break that. Such a massive name...
July 22, 2025 at 7:48 PM
Writing a manuscript takes time, and organizing figures covers a large portion of that time. Each time I export a figure, a suffix is added indicating the number of previous versions. You see it's the 50th version of the same figure and I'm not even sure whether this will be the final version.
July 9, 2025 at 12:43 PM
Reposted by Yiğitcan Sümbelli
Watch the latest Blackboard Lunch talk on "Liquid-liquid phase separations and condensates in and out of equilibrium" by Shura Grosberg (‪#NYU), from the ongoing #KITP Program: Physical Principles Shaping Biomolecular Condensates #biomol25 buff.ly/Qmu5521 🧪
Liquid-liquid phase separations and condensates in and out of equilibrium | Shura Grosberg (NYU)
The purpose of these Blackboard Talk lunches is for the science of one program to be explained to the other KITP program participants. These talks lead to cr...
youtu.be
June 3, 2025 at 4:30 PM
Reposted by Yiğitcan Sümbelli
In the context of our @reviewcommons.org revision process, I'm happy to announce Microscopy Nodes v2.2.0!
This packs lots of new fun features, including new color management 🌈, clearer transparency handling 🫥, custom default settings 🔧 and more!
Preprint at doi.org/10.1101/2025...
May 23, 2025 at 1:13 PM
We attended the annual symposium of @synbionl.bsky.social #synbionl2025 with Madelief, and presented some cool stuff from our projects related to controlled formation of subcellular structures within our artificial cells. It was a fun day!
May 2, 2025 at 2:25 PM
I came here from a country where they were actively making it hard to do scientific research. Now, the Netherlands is doing a similar thing. They're ruining higher education actively and passively. Why do governments sabotage their future like this? Isn't the cost of such an act obvious?
April 23, 2025 at 7:17 PM
As a scientist, I have tattoos about my MSc and PhD theses, and I love them!
Nature Careers spoke to scientists about their tattoos, which include scientific images to mark career accomplishments and illustrate research passions. #Academicsky 🧪
Science on our sleeves: the research that inspires our tattoos
Inked scientists choose scientific images to mark career accomplishments and illustrate their research passion.
go.nature.com
April 20, 2025 at 8:03 PM
Interestingly (!), they saw that when they paid the reviewers, the review quality did not get worse. It's good to see paying peer reviewers is under trial by some publishers.

www.nature.com/articles/d41....
Publishers trial paying peer reviewers — what did they find?
Two journals embarked on efforts to compensate reviewers, with different results.
www.nature.com
March 31, 2025 at 9:50 AM
Reposted by Yiğitcan Sümbelli
I wrote something... about writing. #ScientificWriting to be exact, but I think it applies to all kinds of #writing.
An open letter to graduate students and other procrastinators: it’s time to write
Nature Biotechnology - An open letter to graduate students and other procrastinators: it’s time to write
rdcu.be
March 17, 2025 at 5:52 PM
Please someone correct me if I got this wrong: the recent Dutch government made it clear that they don't want foreign students anymore and said that the money being spent on them was too much. They also decided that money being spent on research was too much in general. 1/3
March 21, 2025 at 6:44 AM
Reposted by Yiğitcan Sümbelli
💡 Looking for #FacultyPositions in Europe? The search can be a maze!

I shared my personal journey in this @cp-matter.bsky.social article, thanks to an invite from @cranfordmatter.bsky.social.

🔓 Free access here 👉 authors.elsevier.com/c/1kZ4b9Cyxd...

#chemsky #AcademicLife #CareersInScience
February 18, 2025 at 10:32 AM
I'm sure everyone has been telling you this but let me do it as well: getting a PhD is an emotional rollercoaster.
You live by those small glimpses of successful experiments in between a ton of failures. Everyday is a new journey and you try to keep it stable.
February 8, 2025 at 8:12 AM
Reposted by Yiğitcan Sümbelli
Watch out for those bastard professors
January 7, 2025 at 7:53 PM
Reposted by Yiğitcan Sümbelli
By mapping the meanings of the words used to communicate emotions across more than one-third of the planet’s spoken languages, a study in Science found that there is significant variation in how emotions are expressed across cultures. #ScienceMagArchives scim.ag/41X6dDk
Emotion semantics show both cultural variation and universal structure
Analysis of the terms used for emotions across a sample of 2474 spoken languages reveals low similarity across cultures.
scim.ag
December 26, 2024 at 2:38 PM
Reposted by Yiğitcan Sümbelli
Instead of listing my publications, as the year draws to an end, I want to shine the spotlight on the commonplace assumption that productivity must always increase. Good research is disruptive and thinking time is central to high quality scholarship and necessary for disruptive research.
December 20, 2024 at 11:18 AM
Reposted by Yiğitcan Sümbelli
I had the great pleasure of coordinating our annual "35 challenges in materials science". Was super fun to organise and engage with all these brilliant scientists!

Take a look at what this year's cohort of materials scientists are working on!

#Matter

www.cell.com/matter/abstr...
35 challenges in materials science being tackled by PIs under 35(ish) in 2024
Here, we highlight 35 global researchers approximately under the age of 35. This third annual cohort was self-generated by initial seed invitations sent by the editorial team, with each contributor su...
www.cell.com
November 21, 2024 at 5:17 PM
Even after you finish you keep thinking "I could've done this and that"...
"Done"
December 17, 2024 at 7:07 PM