Structural Biology
@actacrystd.iucr.org
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Acta Crystallographica Section D: Structural Biology is a leading structural biology journal published by the IUCr. journals.iucr.org/d
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Reposted by Structural Biology
Reposted by Structural Biology
Structural Biology
@actacrystd.iucr.org
· Aug 28
Crystal structures of 40- and 71-substitution variants of hydroxynitrile lyase from rubber tree
Variants HNL16, HNL40 and HNL71 of hydroxynitrile lyase from Hevea brasiliensis contain 16, 40 and 71 mutations, respectively, to make increasingly larger regions surrounding the active site identical in sequence to the esterase SABP2. X-ray structures of HNL40 and HNL71 reveal changes to the oxyanion hole and a new tunnel, which may contribute to their efficient esterase activity.
journals.iucr.org
Reposted by Structural Biology
Mike Hough
@mikehough.bsky.social
· Aug 22
Time-resolved serial synchrotron and serial femtosecond crystallography of heme proteins using photocaged nitric oxide
We demonstrate the application of a nitric oxide releasing photocage system for time-resolved serial crystallography studies of two heme containing proteins using a fixed target sample delivery system...
journals.iucr.org