adityakamat.bsky.social
Aditya Kamat
@adityakamat.bsky.social
67 followers 100 following 3 posts
Postdoctoral fellow at Rudner Lab @harvardmed | PhD at Badrinarayanan Lab @NCBS_Bangalore
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adityakamat.bsky.social
Aditya Kamat @adityakamat.bsky.social · Jan 29
There's more to SOS response timing than the LexA repressor. In our preprint from the Anjana Badrinarayanan @anjbadri.bsky.social Lab, we uncover a new regulatory layer that imparts temporal structure to the bacterial SOS response.

www.biorxiv.org/content/10.1...
Variability in intrinsic promoter strength underlies the temporal hierarchy of the Caulobacter SOS response induction
Bacteria encode for gene regulatory networks crucial for sensing and repairing DNA damage. Upon exposure to genotoxic stress, these transcriptional networks are induced in a temporally structured mann...
www.biorxiv.org
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Reposted by Aditya Kamat
tunglejic.bsky.social
Tung Le @tunglejic.bsky.social · 5d
Independent research fellowships leading to tenured positions at the John Innes Centre.

Repost = nice. Thank you very much!!!
johninnescentre.bsky.social
John Innes Centre @johninnescentre.bsky.social · 5d
Shortlisted candidates will be invited to give a seminar at the Fellows Conference, which will be held on 10 March 2026.

Candidates who win Fellowships will be offered a Tenure Track Group Leader position from the outset, initially for 5 years.

Find out more: www.jic.ac.uk/training-car...
Independent Research Fellowships Leading to Tenured Faculty Positions | John Innes Centre
The John Innes Centre (JIC), is a world leading centre of excellence in plant and microbial sciences based on the Norwich Research Park, UK. We are inviting applications from outstanding researchers…
www.jic.ac.uk
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Reposted by Aditya Kamat
goleylab.bsky.social
Erin Goley @goleylab.bsky.social · 19d
🚨🚨🚨Calling all Caulophiles and Alpha aficionados - stayed tuned for a virtual CauloCon in early 2026. And HOPEFULLY an in person alpha meeting in 2027!! DM me or @chienlab.bsky.social w questions or to stay in the know.
two men are standing next to each other and one of them is saying `` you wanna hang out shoot the breeze ''
ALT: two men are standing next to each other and one of them is saying `` you wanna hang out shoot the breeze ''
media.tenor.com
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Reposted by Aditya Kamat
lalouxlab.bsky.social
Géraldine Laloux @lalouxlab.bsky.social · 22d
🚨New paper out! #MicroSky
Studying obligate predators like Bdellovibrio bacteriovorus is tricky—essential genes for predation are also essential for survival.
We expanded its genetic toolbox:
🧬promoters to fine-tune expression
🧬IPTG-inducible system
🧬CRISPRi for rapid knockdown
bit.ly/46GUn2c
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Expanding the genetic toolbox of the obligate predatory bacterium Bdellovibrio bacteriovorus with inducible gene expression and CRISPR interference
Inducible gene expression and CRISPR interference-mediated depletion in the predatory bacterium Bdellovibrio bacteriovorus.
academic.oup.com
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Reposted by Aditya Kamat
evolvedbiofilm.bsky.social
Ákos T Kovács @evolvedbiofilm.bsky.social · Aug 21
N6-methyladenine modification of DNA enhances RecA-mediated homologous recombination

www.pnas.org/doi/10.1073/...
N6-methyladenine modification of DNA enhances RecA-mediated homologous recombination | PNAS
Both DNA methylation and homologous recombination (HR) are extensively studied. In bacteria, Dam methylation is the most studied DNA modification, ...
www.pnas.org
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Reposted by Aditya Kamat
archaellum.bsky.social
Sonja-Verena Albers @archaellum.bsky.social · Aug 20
🚨 Imagine a bacterium that refuses to follow the textbook:
It grows as tangled filaments, divides unevenly, reshapes its own membranes… and even builds grappling hooks.
Meet Litorilinea aerophila — and here’s why it blew our minds.
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Reposted by Aditya Kamat
youngbiophymeet.bsky.social
Young Biophysicists Meeting @youngbiophymeet.bsky.social · Aug 18
Biophysics enthusiasts, do consider applying for the seventh session of YBM! Submit your abstracts by 20th August.
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Reposted by Aditya Kamat
lalouxlab.bsky.social
Géraldine Laloux @lalouxlab.bsky.social · Jul 25
#MicroSky Summer read!

Predatory bacteria kill and eat other bacteria. Their deadly actions come in many flavors, often via direct physical contact between predator &
prey 🧛

How do they do it?
Our review 📖 @coralietesseur.bsky.social @ysantin.bsky.social

www.sciencedirect.com/science/arti...
Strategies and mechanisms of contact-dependent predation in bacteria
Predatory bacteria kill other bacteria to acquire nutrients. Among diverse strategies to kill and feed on prey, contact-dependent predation stands out…
www.sciencedirect.com
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Reposted by Aditya Kamat
danielabarilla.bsky.social
Daniela Barillà @danielabarilla.bsky.social · Jul 22
And the story is published now!🍾
www.nature.com/articles/s41...

Open access link: rdcu.be/exnOc

Many years in the making, great collaboration with @archaellum.bsky.social & @tunglejic.bsky.social

Thanks @ukri.org BBSRC & @leverhulme.ac.uk for funding, reviewers & editor!! 🙏
#microsky #archaeasky
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Reposted by Aditya Kamat
youngbiophymeet.bsky.social
Young Biophysicists Meeting @youngbiophymeet.bsky.social · Jul 17
Theoretical physics enthusiasts, do consider submitting an abstract for the upcoming sixth YBM!

Submit your abstracts here: t.co/W1qGraRpAc
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Reposted by Aditya Kamat
molabuw.bsky.social
Mo lab @molabuw.bsky.social · Jul 10
In @elife.bsky.social: Bacteriophage infection drives loss of β-lactam resistance in methicillin-resistant Staphylococcus aureus doi.org/10.7554/eLif...
Bacteriophage infection drives loss of β-lactam resistance in methicillin-resistant Staphylococcus aureus
In methicillin-resistant Staphylococcus aureus, evolution of bacteriophage resistance causes trade-offs that re-sensitize the bacteriato β-lactam antibiotics.
doi.org
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Reposted by Aditya Kamat
s-lab.bsky.social
Susan Schlimpert @s-lab.bsky.social · Jul 9
Happy to see our collaborative work on the contractile injection system (CIS) in Streptomyces published. We show that the membrane protein CisA gives Streptomyces CIS a licence to kill.
@pilhoferlab.bsky.social & Bastien Casu, @joesallmen.bsky.social #MicroSky

elifesciences.org/articles/104...
Function and firing of the Streptomyces coelicolor contractile injection system requires the membrane protein CisA
CryoEM, genetic, and cell biological analyses reveal that the conserved membrane protein CisA mediates membrane recruitment of contractile injection systems Streptomyces coelicolor, enabling their act...
elifesciences.org
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Reposted by Aditya Kamat
youngbiophymeet.bsky.social
Young Biophysicists Meeting @youngbiophymeet.bsky.social · Jul 4
The fifth session of YBM is coming up next week. Join us for two exciting talks on Monday (7th July) at 11am (EDT).

Mark your calendars🗓️: tinyurl.com/29b7yk47
Meeting link: shorturl.at/0ng5A
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Reposted by Aditya Kamat
tunglejic.bsky.social
Tung Le @tunglejic.bsky.social · Jul 2
Finally published! Many thanks to the reviewers and editor whose comments & suggestions improved this work significantly more than the first preprint version!!!

www.pnas.org/doi/10.1073/...
Expanding the diversity of bacterial DNA partitioning: A CTP-independent ParABS system for plasmid partitioning in Streptomyces | PNAS
The ATP- and CTP-dependent ParA-ParB-parS segrosome is a macromolecular complex that segregates chromosomes/plasmids in most bacterial species. CTP...
www.pnas.org
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Reposted by Aditya Kamat
amelia-mckitterick.bsky.social
Amelia McKitterick @amelia-mckitterick.bsky.social · Jun 25
The excitement continues! Check out my latest preprint examining how phages have adapted to lyse different bacterial envelopes. I found a lysis gene (lysZ) that is conserved in phages that infect corynebacteria mycobacteria, and other actinos.

www.biorxiv.org/content/10.1...
Bacteriophages target membrane-anchored glycopolymers to promote host cell lysis and progeny release
Most bacteriophages lyse their host cell to release progeny virions. Double-stranded DNA phages typically promote host lysis using a holin-endolysin system. Holins form pores in the cytoplasmic membra...
www.biorxiv.org
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Reposted by Aditya Kamat
amelia-mckitterick.bsky.social
Amelia McKitterick @amelia-mckitterick.bsky.social · Jun 24
I'm pleased to announce that I will be starting my lab as an Assistant Professor at UMass Chan Medical School in August! My group will study phages that infect corynebacteria and mycobacteria to understand bacterial cell envelope assembly and phage gene function. Website and more info to come soon!
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ncbsbangalore.bsky.social
National Centre for Biological Sciences, Bengaluru @ncbsbangalore.bsky.social · Jun 19
#PhDone! 🎓 Congratulations Dr Shivangi Verma! 🎊
@shivangiv10.bsky.social from Prof Vatsala Thirumalai's lab successfully defended her thesis!

🧵👇Check out the thread to learn more about her work on understanding how neuronal networks are sculpted in the cerebellum during development 🧠

(1/5)
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Reposted by Aditya Kamat
apbrogan.bsky.social
anna brogan @apbrogan.bsky.social · Jun 17
Very happy to share that a large part of my thesis work is out today: B. subtilis uses the second messenger c-di-AMP to modulate its turgor pressure in response to the state of its cell envelope. www.nature.com/articles/s41...
Cyclic-di-AMP modulates cellular turgor in response to defects in bacterial cell wall synthesis - Nature Microbiology
Brogan et al. uncover a signalling pathway in which levels of the nucleotide second messenger c-di-AMP increase in response to defects in cell wall synthesis. This regulatory pathway decreases turgor ...
www.nature.com
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Reposted by Aditya Kamat
veeninglab.com
Jan-Willem Veening @veeninglab.com · Jun 15
Some positive news in troubled times: New preprint by Vincent de Bakker, Xue Liu @jonbakerlab.bsky.social Infection-mimicking conditions+transcriptomics/proteomics/'essentialomics'/lipidomics shows many cool things!
www.biorxiv.org/content/10.1...
Multi-omics profiling reveals atypical sugar utilization and identifies a key membrane composition regulator in Streptococcus pneumoniae
The human body comprises many different microenvironments, each with their own challenges for microorganisms to overcome in order to survive, and possibly cause infection. The human pathogen Streptoco...
www.biorxiv.org
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Reposted by Aditya Kamat
jiexiaolab.bsky.social
Jie Xiao @jiexiaolab.bsky.social · Jun 11
Join us at the BPS Thematic Meeting on Spatial Organizations of Biological Functions in beautiful Bangalore, India! The early registration deadline is July 21st, 2025. www.biophysics.org/meetings-eve...
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Reposted by Aditya Kamat
brunlabcaulo.bsky.social
Yves Brun lab @brunlabcaulo.bsky.social · Jun 2
How does your favorite species elongate? 🧵 "Phenotypic plasticity in bacterial elongation among closely related species". Happy to see this paper in print @natcomms.nature.com. Nice work by @mariedelaby.bsky.social, Liu Yang et al. See original 🧵, different colours, same data and conclusions.
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adityakamat.bsky.social
Aditya Kamat @adityakamat.bsky.social · Jun 2
Starting in 15 minutes...
youngbiophymeet.bsky.social
Young Biophysicists Meeting @youngbiophymeet.bsky.social · May 29
We have three exciting talks lined up for the Fourth Young Biophysicists Meeting. See you all soon on the coming Monday (June 2) at 11am!

Mark your calendar🗓️: shorturl.at/choBf
Find out moreℹ️: shorturl.at/4oKNe
Reposted by Aditya Kamat
contamclub.bsky.social
Contamination Club @contamclub.bsky.social · Jun 2
🚨 Very excited to finally say… 🚨

The story of Noodlococcus - the contaminant that started ContamClub - is available to read 📖🍜🦠

Check it out ➡️ doi.org/10.1101/2025...

1/15 🧵
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Reposted by Aditya Kamat
stemartiniani.bsky.social
Stefano Martiniani @stemartiniani.bsky.social · Jun 2
🚀 Satyam and Guanming’s “Emergent Universal Long Range Structure in Random-Organizing Systems” shows noise correlations create long-range structure, from 🧩 hyperuniform materials to 🤖 ML, and that SGD’s flat minima bias is universal. 👇 arxiv.org/abs/2505.22933 #SoftMatter #ML
Emergent universal long-range structure in random-organizing systems
Self-organization through noisy interactions is ubiquitous across physics, mathematics, and machine learning, yet how long-range structure emerges from local noisy dynamics remains poorly understood. ...
arxiv.org
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Reposted by Aditya Kamat
fleshball.bsky.social
Ethan Garner @fleshball.bsky.social · May 20
I’m excited that the work by Diego Ramirez and Lei Yin is out, where they gained several key insights into what provides the force underlying bacterial cell division doi.org/10.1101/2025....

To divide, cells must first bend the membrane inward, a process that’s energetically expensive
The interplay of membrane tension and FtsZ filament condensation on the initiation and progression of cell division in B. subtilis
The first step of cell division is deforming the planar cell membrane inward towards the cytoplasm. As deforming membranes is energetically costly, biology has developed various protein systems to acc...
doi.org
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adityakamat.bsky.social
Aditya Kamat @adityakamat.bsky.social · May 17
Deadline to apply is just around the corner!
youngbiophymeet.bsky.social
Young Biophysicists Meeting @youngbiophymeet.bsky.social · May 11
Submission deadline for the fourth YB Meeting closes in 1 week (19th May)! Abstract submission link: forms.gle/SBeQeAp9MR2U...