Daniela Barillà
@danielabarilla.bsky.social
1.2K followers 1K following 220 posts
Microbial geneticist interested in large and small DNA 🧬 rings in bacteria and archaea. Living in Brontë country and based at the University of Old York. https://barillalabyork.weebly.com/
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danielabarilla.bsky.social
And the story is published now!🍾
www.nature.com/articles/s41...

Open access link: rdcu.be/exnOc

Many years in the making, great collaboration with @archaellum.bsky.social & @tunglejic.bsky.social

Thanks @ukri.org BBSRC & @leverhulme.ac.uk for funding, reviewers & editor!! 🙏
#microsky #archaeasky
Reposted by Daniela Barillà
pcmfogg.bsky.social
Still a couple of days left to apply for this postdoc #job. With access to world-class facilities, you will unravel the DNA-packaging mechanisms used by #phages and the unusual #GeneTransferAgents, and explore the impact of these tiny machines on evolution, resistance, and biotech. @ukri.org #bbsrc
pcmfogg.bsky.social
🚨Exciting #Postdoc opportunity in the Fogg & Antson labs: 3-year post based @biologyatyork.bsky.social to explore the #StructuralBiology & mechanism of viral DNA-packaging motors using cutting-edge #Cryo-EM, biophysical and molecular approaches. Apply by 9th Oct at bit.ly/3Iz3bOu #ScienceJobs
Jobs - The University of York
bit.ly
Reposted by Daniela Barillà
artecalabria.bsky.social
Bizantine style:
Vicino al castello aragonese di Reggio #Calabria troviamo la Chiesa degli Ottimati, edificio sacro di età bizantina (X sec. d.C.) con il suo pavimento cosmatesco del XII sec.
I normanni apportarono modifiche strutturali
#Calabria #arte #heritage #beauty #medieval #love #church
Reposted by Daniela Barillà
oborkowski.bsky.social
SHARK: a specialized host for assembling R6K plasmids
doi.org/10.1101/2025...
Reposted by Daniela Barillà
daumlab.bsky.social
Out in Science Advances: Our #cryoEM structure of HFTV1, a virus infecting the halophile #archaea. *First full atomic structure (containing all structural proteins) of any tailed virus!* Congrats and thanks to all co-authors and our fantastic collaborators! www.science.org/doi/10.1126/...
Cryo-EM resolves the structure of the archaeal dsDNA virus HFTV1 from head to tail
This structure of an archaeal tailed virus (arTV) provides detailed insights into arTV assembly and infection mechanisms.
www.science.org
Reposted by Daniela Barillà
danielabarilla.bsky.social
Holgate windmill, a little jewel and proper working mill consisting of five lovingly restored floors in #York. Visited last weekend for free during #YorkUnlocked #VisitYork #Yorkshire
Holgate Windmill painted black with mill stones on the external wall and a cloudy sky in the background.
Reposted by Daniela Barillà
pcmfogg.bsky.social
Fantastic @biologyatyork #Microbial_Life seminar yesterday by Mark Dillingham, @dillinghamlab.bsky.social 🧬🧪. An engaging talk and fascinating to hear about RecBCD, phage-host arms race, DNA mimics and the enigmatic retrons! Massive thanks to BIO-RAD, Starlab and BMKGENE for their sponsorship.
Mark Dillingham facing the audience while presenting a talk at the University of York. Protein structures of the RecBCD complex are shown on the projector screen.
Reposted by Daniela Barillà
giuliotesei.bsky.social
I'm hiring for a PhD position at Malmö University, Sweden!

The project will focus on molecular modelling of proteins, lipids, and biomolecular condensates at cell membranes.

More details and application form: tinyurl.com/4zm92365

Please feel free to share!

@vetenskapsradet.bsky.social | @mau.se
Snapshot of a condensate near a lipid membrane with Swedish Research Council and Malmö University logos.
Reposted by Daniela Barillà
steve-quinn-lab.bsky.social
We are delighted that our latest @york.ac.uk & @ybri-uoy.bsky.social work showcasing our photonic biosensor for Alzheimer's disease blood biomarkers has been published in @optica.org!
👇
opg.optica.org/optica/fullt...

Thanks to @alzheimerssoc.bsky.social & @alzheimersresearchuk.org for support!
Optica Publishing Group
opg.optica.org
Reposted by Daniela Barillà
thanbichlerlab.bsky.social
Now published as a Version of Record, with various new results compared to the initial preprint:

Membrane binding properties of the cytoskeletal protein bactofilin

Available at:
elifesciences.org/articles/100...

@synmikro.bsky.social @unimarburg.bsky.social @mpimicrobiomarburg.bsky.social
Reposted by Daniela Barillà
ec.europa.eu
#ChooseEurope for Science is live!

With €22.5 million under #MSCA, we’re funding organisations to:

🔬 Host postdoctoral researchers in all fields
🔬 Offer stable jobs and great working conditions
🔬 Create long-term career prospects

Europe is where science thrives.

More → link.europa.eu/6JhtHp
A visual featuring a black-and-white photo of Marie Skłodowska-Curie. On the left, text reads "Choose EUROPE for Science." Below it says, "Marie Skłodowska-Curie Actions €22.5 million for researchers." On the right is the European Union flag with yellow stars on a blue background.
Reposted by Daniela Barillà
dirkscheffers.bsky.social
One would hope that King Charles III withdraws the royal predicate until the moment this Society has relocated its spine and has removed a member that has basically called for the overthrow of Charles’ government.
Reposted by Daniela Barillà
imrsankhan.bsky.social
Our work deciphering the substrate preferences of a di-/tripeptide transporter from S. aureus is now available as a proof at @plos.org Pathogens! Big thanks to the reviewers and to all the brilliant co-authors, particularly Callum who helped get those last few crucial experiments across the line
Defined roles for the Staphylococcus aureus POT transporter DtpT in di/tripeptide uptake and glutathione utilisation inside human macrophages
Author summary The environments where bacterial pathogens thrive are often rich in proteins and their degradation products, including oligopeptides, which can be taken up by the bacterium and used as ...
journals.plos.org
Reposted by Daniela Barillà
natmicrobiol.nature.com
Some keen Observations in Our October issue!

🦠 Cancer microbiome
🌊 Marine microbes in warming oceans
🌐 broad-range phages
🧬 genetically minimised Salmonella
🔧 Viral infection mechanisms
🧪 Oxaloacetate antiviral defence

and more, here: www.nature.com/nmicrobiol/v...
Reposted by Daniela Barillà
dportik.bsky.social
New pre-print from the Banfield lab, highlighting an interesting case of 1.5Mb megaplasmids found in human gut.

Plasmid genomes were resolved using #PacBio HiFi sequencing with hifiasm-meta for #metagenome assembly. Host association was detected using epigenetic signals.

doi.org/10.1101/2025...
Megaplasmids associate with Escherichia coli and other Enterobacteriaceae
Humans and animals are ubiquitously colonized by Enterobacteriaceae , a bacterial family that contains both commensals and clinically significant pathogens. Here, we report Enterobacteriaceae megaplas...
doi.org
danielabarilla.bsky.social
What an inspiring and evocative title, Ricordanze, and what a great story! Congratulations on the final product after many years of work. 👏
Reposted by Daniela Barillà
lucas.farnunglab.com
New week, new tool: Find our Protein Domain Designer tool to generate publication-ready protein domain diagrams here: domaindesigner.farnunglab.com
Protein Domain Designer tool for the generation of publication-ready protein domain diagrams
Reposted by Daniela Barillà
artecalabria.bsky.social
Castello di Condojanni frazione Sant'Ilario dello Ionio (RC), eretto dai Normanni nel 1068 su un'altura che domina la locride e la costa.
Spicca possente donjon a basa quadrata, da documenti sappiamo che nel periodo svevo furono aggiunte delle torri.
#Calabria #art #beauty #love #landscape
Reposted by Daniela Barillà
theplanetaryguy.bsky.social
Saturn, rising behind its largest moon Titan.

This scene is a composite of images taken by the Cassini spacecraft on 31 March 2005. At the time, Cassini was 7,000 km from Titan and 1.2 million km from Saturn.

Credit: NASA/JPL/SSI/Ian Regan/Val Klavans
In the foreground is Saturn's giant moon Titan, its hazy, peach-coloured atmosphere extending into space. Behind is Saturn itself, its upper hemisphere crossed by the shadows of its vast ring system.