Didier Mazel
@amazeld.bsky.social
Bacterial geneticist, Prof @ Institut Pasteur.
The role of these additional PDFs is not always clear, many copies confer resistance to natural and synthetic anti-deformylases, and what's more, they are already found in integron cassettes! Congratulations to @morgan-lamberioux.bsky.social my student who led this "Back to the Future" project.
December 12, 2025 at 8:57 AM
The role of these additional PDFs is not always clear, many copies confer resistance to natural and synthetic anti-deformylases, and what's more, they are already found in integron cassettes! Congratulations to @morgan-lamberioux.bsky.social my student who led this "Back to the Future" project.
A key observation, explaining the easiness of cassette exchange among vibrios! Another brick from our lab. Kudos @kdebatisse.bsky.social and @celineloot.bsky.social as well as @eloilittner.bsky.social and @epcrocha.bsky.social !
November 18, 2025 at 4:45 PM
A key observation, explaining the easiness of cassette exchange among vibrios! Another brick from our lab. Kudos @kdebatisse.bsky.social and @celineloot.bsky.social as well as @eloilittner.bsky.social and @epcrocha.bsky.social !
Reposted by Didier Mazel
Congratulations to PhD students Jasmin Ostermayer and Noa Guzzi (co–first authors 🎉), together with Jakub Czarnecki and Alfonso Soler-Bistué, for compressing the diverse, lineage-wide literature on large extrachromosomal replicons into <5000 words and 80 references 😅
August 20, 2025 at 3:46 PM
Congratulations to PhD students Jasmin Ostermayer and Noa Guzzi (co–first authors 🎉), together with Jakub Czarnecki and Alfonso Soler-Bistué, for compressing the diverse, lineage-wide literature on large extrachromosomal replicons into <5000 words and 80 references 😅
Reposted by Didier Mazel
Our paper is published back2back with one from @amazeld.bsky.social and @epcrocha.bsky.social labs where @baptistedarracq.bsky.social, @eloilittner.bsky.social and co. show that Sedentary Chromosomal Integrons are biobanks of phage defense systems. www.science.org/doi/10.1126/...
Sedentary chromosomal integrons as biobanks of bacterial antiphage defense systems
Integrons are genetic systems that drive bacterial adaptation by acquiring, expressing, and shuffling gene cassettes. While mobile integrons are well known for spreading antibiotic resistance genes, t...
www.science.org
May 8, 2025 at 8:27 PM
Our paper is published back2back with one from @amazeld.bsky.social and @epcrocha.bsky.social labs where @baptistedarracq.bsky.social, @eloilittner.bsky.social and co. show that Sedentary Chromosomal Integrons are biobanks of phage defense systems. www.science.org/doi/10.1126/...