Andrew Gulick
@amgulick-lab.bsky.social
120 followers 110 following 62 posts
Structural Biology Lab – focused on remarkable enzymes of natural product biosynthesis
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Reposted by Andrew Gulick
nrpspapers.bsky.social
A rapid combinatorial assembly method for gene cluster characterisation illuminates glidobactin biosynthesis https://pubmed.ncbi.nlm.nih.gov/41050206/
amgulick-lab.bsky.social
Find a scientific community* to join. Regularly attend their conferences and contribute in meaningful ways. Don't flit about from topic to topic.

Added benefit: making lifelong friends from across the globe.

*not necessarily a formal society
amgulick-lab.bsky.social
correction: "directing PIs to put all their eggs in one basket."
jeremymberg.bsky.social
Here is NIGMS.

This reflects Jon Lorsch's push away from R01s and toward MIRA awards (R35s). While there are some advantages to the R35 mechanism, there are downsides to "putting all of your eggs in one basket" as some discovered this year.

8/n
amgulick-lab.bsky.social
I too strongly endorse this essay.
lewislab.bsky.social
"I would argue that this [research service] is no less so, and no less important, than when our country requests some of our young people to join the military."

I really like this framing of how to think about research fellowships and their purpose.
drugmonkey.bsky.social
On the nature of a NSF (or NIH) graduate training fellowship drugmonkey.wordpress.com/2025/09/29/o...
Reposted by Andrew Gulick
giantmolecular.cloud
It seems the GRFP solicitation is FINALLY released (like 5 minutes ago)! Due dates have also been pushed back, thankfully! 🧪 🔭

www.nsf.gov/funding/oppo...
NSF Graduate Research Fellowship Program (GRFP)
www.nsf.gov
Reposted by Andrew Gulick
kateduncan.bsky.social
There seems to quite a few new faces lately, so if I haven’t already added you, but you’d like added please let me know and for anyone interested in following more microbial natural products folks, then our starter pack is now 100 strong go.bsky.app/72NeGsT
Reposted by Andrew Gulick
challis-group.bsky.social
Lona Alkhalaf will speak about the discovery, structure, and mechanism of a cool new family of enzymes discovered by the group at the 29th Enzyme Mechanisms Conference.

www.enzymemechanismsconference.org/speakers
Speakers | emc2026
www.enzymemechanismsconference.org
Reposted by Andrew Gulick
stephanieaw.bsky.social
Structural bioinformatics is incredibly powerful on its own or when paired with theory or experiment. One of the PDB's superpowers isn’t from one structure, but comparing many to uncover folds, binding sites, and subtle conformational shifts. chemrxiv.org/engage/chemr...
10 Rules for a Structural Bioinformatic Analysis
The Protein Data Bank (PDB) is one of the richest open‑source repositories in biology, housing over 277,000 macromolecular structural models alongside much of the experimental data that underpins thes...
chemrxiv.org
amgulick-lab.bsky.social
When I've had a few spare minutes for the past few weeks, I've spent it browsing the literature and writing emails to authors of enzymology papers who are not part of the EMC mailing list.

www.enzymemechanismsconference.org

Too many people who otherwise should don't know about this gem.
Screen capture of text from EMC invitation email
amgulick-lab.bsky.social
You'll laugh but...

This is how I feel watching a Mets game when they have a big lead in the late innings and the TV pans across the diversity of fans at Citi Field:
hormiga.bsky.social
Hanging out in arrivals of a big international airport. If humanity is getting you down, this will always pick you up.
Reposted by Andrew Gulick
mayakaufman.bsky.social
BREAKING, from NY Playbook PM: New York Gov. Kathy Hochul will sign an executive order allowing pharmacists to prescribe and administer Covid vaccines to New Yorkers who request them.
amgulick-lab.bsky.social
One presentation will be selected as the Founders Award winner and promoted to give a full talk.

Please encourage your students/post-docs to apply and we hope to see you in January!

(end)
amgulick-lab.bsky.social
The Trainees page at the Enzyme Mechanisms Conference website is updated. Students and Postdocs can submit a 3 minute flash talk "audition" for one of 10 slots to be presented before the poster sessions.

www.enzymemechanismsconference.org/junior-inves...

(1/2)
Junior Investigators | emc2026
www.enzymemechanismsconference.org
Reposted by Andrew Gulick
jeremymberg.bsky.social
Yes, it was carefully hidden in the New England Journal of Medicine.

Pfizer/BioNTech vaccine (www.nejm.org/doi/pdf/10.1... )

1/2
A graph comparing COVID incidence after the Pfizer vaccine compared to placebo
Reposted by Andrew Gulick
davidimiller.bsky.social
🧪 And House appropriators say: no cuts to NIH budget!

House subcommittee version just came out (link below). Holds NIH flat at $48 billion.

To be clear: this is far from over. But a good sign that science still matters across both sides of aisle.

YOUR VOICE MATTERS!!
Reposted by Andrew Gulick
jamestaylor-com.bsky.social
Turns out it doesn't even matter if the sound goes out for an entire minute in the middle of a concert if you have the right audience. Great job, everyone at MGM Music Hall at Fenway! And thanks to #LuisConte for the percussion-eye view. youtu.be/NHcAFVxvuEE

#JT #JamesTaylor #2025Tour
Sound Loss at MGM Music Hall - James Taylor
YouTube video by James Taylor
youtu.be
Reposted by Andrew Gulick
ubuffalo.bsky.social
The Interlocking UB, loading in 3...2...1 ⏩ Welcome to the herd, Bulls! We're so glad to have you at #UBuffalo 💙 #UBTrueBlue 🤘🏾
Reposted by Andrew Gulick
chimerax.ucsf.edu
Here's how to predict binding of tens or hundreds of small molecules to protein assemblies using Boltz 2 in ChimeraX.
Accuracy depends on how similar the ligands and binding pockets are to existing experimental structures.
www.rbvi.ucsf.edu/chimerax/dat...
Reposted by Andrew Gulick
ubuffalo.bsky.social
#AI for social good 🫱🏼‍🫲🏽 During his visit to #UBuffalo, SUNY chancellor John B. King saw demos from faculty and students showcasing how Empire AI is driving solutions that can improve lives across the globe. Learn more 🔽
King marvels at speed of Empire AI
SUNY Chancellor John B. King Jr. received an update on UB's Empire AI-supported work during a visit to campus.
www.buffalo.edu
Reposted by Andrew Gulick
dereklowe.bsky.social
No matter how hard you try, you simply cannot guess the journal withe the highest “impact factor” in organic chemistry last year. Really. Nor will you guess many of the other “winners”:
Journal Impact Nonsense
www.science.org
Reposted by Andrew Gulick
profsje.bsky.social
BIOCHEMISTS! We are looking for a new post-doctoral colleague at BU who will be devoted to a combination of teaching Biochemistry and engaging in Research. Ask me anything! The deadline is short, but the job is awesome. #ChemJobs You can apply here: academicjobsonline.org/ajo/BU/CH/PA...
Boston University, BU Chemistry
Job #AJO30270, Postdoctoral Associate Teaching Scholar, BU Chemistry, Boston University, Boston, Massachusetts, US
academicjobsonline.org