AmirAli Toghani
@amiralito.bsky.social
1.2K followers 950 following 30 posts
Biologist @thesainsburylab.bsky.social. Currently doing a PhD with @kamounlab.bsky.social Curious about plant immune receptors, molecular evolution, and other stuff. 🌿💻 #evoMPMI Find out more here: amiralito.github.io
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Reposted by AmirAli Toghani
kamounlab.bsky.social
The sequences of 91,366 NLR immune proteins from 230 superasterid genomes are now printed in 931 bound volumes #OpenScience #OpenPlantNLR
Reposted by AmirAli Toghani
thesainsburylab.bsky.social
We are pleased to announce that @talbotlabtsl.bsky.social has been awarded the RKS Wood Prize 2026 by the @bspp.bsky.social.

“I am humbled to have been awarded the RKS Wood Prize 2026. I’d like to thank my research group and my TSL colleagues for their inspiration and support.”

buff.ly/VvoR27Q
Nick Talbot, Executive Director and senior group leader at TSL, is pictured in a glasshouse surrounded by rice plants.
Reposted by AmirAli Toghani
tolgaboz.bsky.social
Our latest work on how chloroplasts contribute to immunity: Membrane contact sites between chloroplasts and the pathogen interface underpin plant focal immune responses url: academic.oup.com/plcell/artic...
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Reposted by AmirAli Toghani
borisstojilkovic.bsky.social
Thrilled to share our new bioRxiv preprint!✨ Huge credit to first author Yujin Chen and thanks to all co-authors. Extra special: my first paper as co-corresponding author (with Lieve Gheysen).
Check how nematodes uncouple FLS2–BSK signalling in 🌱👇
www.biorxiv.org/content/10.1...
Reposted by AmirAli Toghani
kamounlab.bsky.social
First a pentamer, then a hexamer… now an octamer!

The riddle of the enigmatic CCG10-NLR immune receptor family cracked open 🔥

Congrats Guanghao @GuanghaoGuo He Zhang @mhz1989 Selva @M__Selvaraj et al.

#NLRbiology #plantsci #immunology
Reposted by AmirAli Toghani
Reposted by AmirAli Toghani
Reposted by AmirAli Toghani
nickdesnoyer.bsky.social
"Little Flower"

A Cryo-SEM portrait of my micro-rose depicting the flower as a sculpture of cells, fractured and frozen in time. Full image is 10k x 10k pixels.
amiralito.bsky.social
Thank you @newphyt.bsky.social for organizing this great meeting. Met some very cool people and had constructive discussions! I presented our most recent work, now published in New Phytologist. You can check out my poster here:
doi.org/10.5281/zeno...
Reposted by AmirAli Toghani
newphyt.bsky.social
Thank you to our brilliant delegates, mentors, speakers, the organising committee and our hosts at the University of Birmingham for making New Phytologist next generation scientists 2025 a great success!
Large group of diverse scientists and researchers gathered outside a modern building for a New Phytologist next generation scientists symposium.
Reposted by AmirAli Toghani
metalichen.bsky.social
Some belated personal news: at the end of July it was my time to say bye to @thesainsburylab.bsky.social and Norwich. Already missing my dear friends and the lab! Big thanks to @talbotlabtsl.bsky.social and everyone else with whom I crossed paths in these 3 years!
me and a group of colleagues assembled in a coffee room me standing next to a big sign saying "Norwich Research Park. Thank you for visiting"
Reposted by AmirAli Toghani
newphyt.bsky.social
To be clear, New Phytologist and @plantspeopleplanet.bsky.social fully support authors that choose to publish their work as preprints, and we welcome submissions submitted in full or part to preprint servers. [3/3]
amiralito.bsky.social
Thanks for the clarification. Beyond the replacement of journals with preprints, I found some of the views regarding publishing practices to be concerning, especially given New Phytologist's stance as a leading figure in the field, promoting open science.
amiralito.bsky.social
Imagine actively vouching for publishing models from the likes of Elsevier and Springer and talking against preprints in an early career meeting. I thought we're promoting open science and inclusive publishing for the new generation 🤷🏻
Reposted by AmirAli Toghani
matteogravino.bsky.social
🎉Thrilled to share our latest work, now published in @newphyt.bsky.social!

🧑‍🔬 @matteogravino.bsky.social, @samtmugford.bsky.social, @saskiahogenhout.bsky.social et al., @johninnescentre.bsky.social

#️⃣ #PlantScience #PlantImmunity

📄 Read the full paper👇
nph.onlinelibrary.wiley.com/share/8QSRJ9...
Model: Activation and suppression of defences in plant–aphid interactions. Upper left panel: aphid stylet penetration of the cell wall releases oligogalacturonides (OGs), which induce PAMP/DAMP-triggered immunity (PTI/DTI) in a process dependent on BRASSINOSTEROID INSENSITIVE 1-ASSOCIATED RECEPTOR KINASE 1 (BAK1), ENHANCED DISEASE SUSCEPTIBILITY 1 (EDS1), and CPK5/6/11 (data herein). The stabilisation of pattern recognition receptors (PRRs) and coreceptors at the plasma membrane may rely on the deubiquitination (DUB) activity of ASSOCIATED MOLECULE WITH THE SH3 DOMAIN OF STAM (AMSHs; Gravino et al., 2024). Upper right panel: the Mp10 effector, introduced by aphids into the cell cytoplasm (Mugford et al., 2016), suppresses OG-induced reactive oxygen species (ROS) (data herein) and flg22-induced PTI (Bos et al., 2010). Mp10 targeting of plant AMSHs is implicated in these processes (Gravino et al., 2024). EDS1 is essential for Mp10-mediated ROS suppression and PRR destabilisation (data herein), acting through an unidentified mechanism (denoted by the double-sided arrow with an asterisk). Lower left panel: effector-triggered immunity (ETI) is activated through EDS1, either directly or indirectly, upon recognition of Mp10 and/or its activities by a TNL (Gravino et al., 2024; Rao et al., 2024). Salicylic acid glucosyltransferase 1 (SGT1) is also required for TNL/ETI activation (Bos et al., 2010). Lower right panel: aphids secrete additional effectors, such as cathepsin B proteins (e.g. CathB6), which target EDS1 to suppress ETI (Liu et al., 2025). Solid arrows, increased activation; solid blunt-ended arrows, increased suppression; Dashed arrows, reduced activation; Dashed -blunt-ended arrows, reduced suppression.
Reposted by AmirAli Toghani
Reposted by AmirAli Toghani
Reposted by AmirAli Toghani
shirasulab.bsky.social
Cryo structure of CARD1 from N. benthamiana transiently produced protein.
Reposted by AmirAli Toghani
audeber.bsky.social
🦠🧍‍♀️From bacterial to human immunity.

We report in @science.org the discovery of a human homolog of SIR2 antiphage proteins that participates in the TLR pathway of animal innate immunity.
Co-led wt @enzopoirier.bsky.social by D. Bonhomme and @hugovaysset.bsky.social

www.science.org/doi/10.1126/...
www.science.org
Reposted by AmirAli Toghani
Reposted by AmirAli Toghani
yanma-fungalls.bsky.social
First Ma lab #GMI paper is now online! It‘s a mini-review on insect-induced plant #galls —their coolness and research potential! Plant galls induced by insects: Coordinated developmental reprogramming and defence manipulation www.sciencedirect.com/science/arti...