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Reposted by Anaïs Baudot

Rob Patro @robp.bsky.social · 14d

RECOMB 2026 website is up! RECOMB will be in Greece :). recomb.org/recomb2026/ --- no paper deadline yet though...

RECOMB 2026 | HOME

RECOMB 2026 - Thessaloniki, Greece

recomb.org

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Paul Villoutreix @paulvilloutreix.bsky.social · 22d

This work was motivated by settings with scarce data such as rare diseases.

It turned into multi-dimensional puzzles and alignement problems that we really enjoyed solving! Congrats to Daniel Lepe-Soltero, the postdoc who led this work.

Link -> arxiv.org/abs/2503.18856

MODIS: Multi-Omics Data Integration for Small and unpaired datasets

An important objective in computational biology is the efficient integration of multi-omics data. The task of integration comes with challenges: multi-omics data are most often unpaired (requiring dia...

arxiv.org

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Paul Villoutreix @paulvilloutreix.bsky.social · 22d

Very happy to share MODIS - a new Multi-Omics Data Integration method for Small and unpaired datasets!

We solve a long-standing problem in the field: how to perform data integration for small unpaired datasets

Our solution: learning with class imbalance on both reference and target datasets!

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Paul Villoutreix @paulvilloutreix.bsky.social · 19d

Link to the preprint ->
www.biorxiv.org/content/10.1...

jsPCA: fast, scalable, and interpretable identification of spatial domains and variable genes across multi-slice and multi-sample spatial transcriptomics data

Spatially structured cell heterogeneity within tissues is essential for healthy organ function. This heterogeneity is reflected by differential gene expression activity at various spatial location. Sp...

www.biorxiv.org

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Reposted by Anaïs Baudot

Paul Villoutreix @paulvilloutreix.bsky.social · 19d

Very happy to introduce jsPCA, a fast and interpretable computational framework for spatial transcriptomics that simultaneously identifies spatial domains and variable genes across multi-slice and multi-sample data.

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Anaïs Baudot @anaisbaudot.bsky.social · Jul 26

Great collaboration with fantastic colleagues :-)
@paulvilloutreix.bsky.social, @cantinilab.bsky.social, Morgane Térézol, and Matthieu Vignes.

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Anaïs Baudot @anaisbaudot.bsky.social · Jul 26

Excited to share David Hirst's PhD work!
🧬 When you only have a few datasets available for multi-omics integration, for instance because you work on rare diseases, one solution is Transfer Learning. Introducing #MOTL - now available in Genome Biology!

doi.org/10.1186/s130...

MOTL: enhancing multi-omics matrix factorization with transfer learning - Genome Biology

Joint matrix factorization is popular for extracting lower dimensional representations of multi-omics data but loses effectiveness with limited samples. Addressing this limitation, we introduce MOTL (...

link.springer.com

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Anthony Mathelier @amathelier.bsky.social · Jul 22

🚨 We're hiring! NCMBM @ncmbm.bsky.social is looking for 2 new group leaders to join our vibrant research community. Ready to build your own group with strong support and a solid startup package?

Interested and attending #ISMBECCB2025? Let’s connect!

🔗 www.jobbnorge.no/en/available...

Group Leader (282908) | University of Oslo

Job title: Group Leader (282908), Employer: University of Oslo, Deadline: Monday, September 8, 2025

www.jobbnorge.no

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NetBio COSI @netbio.bsky.social · Jul 23

👋 We wrap up our #NetBio track 2025 with announcing the #Cytoscape network visualization competition winners (woobox.com/b9poce)

Congrats:
1: Alejandra Paulina Perez Gonzalez
2. Michael Costanzo
3. Jong Chan Lim

👏👏👏 Exciting to have Alejandra and Jong in the audience and congrats to Michael!

NetBio Cytoscape Visualization Competition

woobox.com

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NetBio COSI @netbio.bsky.social · Jul 23

🎉 And now it is time to introduce our last and shared keynote with the Microbiome COSI:
@fionabrinkman.bsky.social is talking about "Microbiome multitudes and metadata madness" connecting the #Microbiome and #NetworkBiology communities!

#ISMBECCB2025

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NetBio COSI @netbio.bsky.social · Jul 23

✨ And it's already time for the last selected #NetBio talk! Piotr Sliwa is presenting "Multilayer Networks Identify Clinically Relevant Patient Endotypes in COVID-19 and Sepsis"

#ISMBECCB2025 #NetworkBiology

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NetBio COSI @netbio.bsky.social · Jul 23

#NetBio talks are continuing in room 1B:

Dongmin Bang is presenting his proceeding paper on "MixingDTA: Improved Drug-Target Affinity Prediction by Extending Mixup with Guilt-By-Association"

doi.org/10.1093/bioi...

#ISMBECCB2025 #NetworkBiology

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NetBio COSI @netbio.bsky.social · Jul 23

🔊 Nicoleta Siminea just presented her work on "Interactome-based computational solutions to support personalized drug therapy decisions in glioblastoma" at the #NetBio track at #ISMBECCB2025!

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NetBio COSI @netbio.bsky.social · Jul 23

🎤 Next up is Terence Egbelo
He is sharing his research on "Improving Target-Adverse Event Association Prediction by Mitigating Topological Imbalance in Knowledge Graphs" with the #NetBio audience! ✨

#ISMBECCB2025 #NetworkBiology #KnowledgeGraphs

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NetBio COSI @netbio.bsky.social · Jul 23

✨Johannes Kersting just presented his cool #Nextflow Pipeline for Network-Based Disease Module Identification and Drug Repurposing

nf-co.re/diseasemodul...
github.com/nf-core/dise...
#ISMBECCB2025 #NetworkBiology #NetBio

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NetBio COSI @netbio.bsky.social · Jul 23

📣Last speaker of the #NetBio morning session:
Samuele Firmani is presenting GATE (Graph Antiviral Target Explorer) to predict disease genes in viral infections with Message Passing Neural Networks"

#ISMBECCB2025 #NetworkBiology