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ANE International

@aneinternational.bsky.social

56 followers 97 following 65 posts

We aim to raise awareness, provide information & support families with #AcuteNecrotizingEncephalopathy. A devastating disease that affects the brain & is typically triggered by influenza & other viruses. www.aneinternational.org

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ANE International @aneinternational.bsky.social · Jul 30

ANE: The Brain Emergency Every Doctor Should Recognize.
#AcuteNecrotizingEncephalopathy

#ANEAwareness #ANE1 #SickKidsToronto #PediatricNeurology #Influenza #BrainHealth #EmergencyPediatrics #RareDiseaseAwareness #ViralEncephalopathy
@arhelnathalie.bsky.social
m.youtube.com/watch?v=ywrf...

ANE Clinical Overview: Symptoms, Diagnosis, and Treatment | Dr. E. Ann Yeh at ANEmone 2025

YouTube video by ANE International

m.youtube.com

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ANE International @aneinternational.bsky.social · 1d

Neurological complications from #influenza - ANE is one that Doctors dread. It typically occurs in previously healthy children. ##vaccinessavelives #ANEawareness
Check our website for symptoms to be aware of. www.aneinternational.org

Voices for Vaccines @voices4vaccines.bsky.social · 1d

Influenza can cause or trigger a brain condition called ANE. Beckett experienced it last flu season.

With vaccines, we hope he doesn't have to again.

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ANE International @aneinternational.bsky.social · 4d

#ANEawareness
#AcuteNecrotizingEncephalopathy

Voices for Vaccines @voices4vaccines.bsky.social · 7d

Influenza can be a very serious disease for otherwise healthy children. Everyone 6 months and up should get vaccinated.

www.voicesforvaccines.org/well-never-m...

We’ll Never Miss a Flu Shot Again

I typically stay on top of vaccines. But in 2023 we were late with flu shots–a mistake I will never make again.

www.voicesforvaccines.org

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ANE International @aneinternational.bsky.social · 4d

Thank you for helping to raise #ANEawareness. #AcuteNecrotizingEncephalopathy is a devastating disease. So many of our community were not vaccinated for influenza. Of those that survive, many live with severe brain injury. #vaccinessavelives

ANE International @aneinternational.bsky.social · 9d

#AcuteNecrotizingEncephalopathy
#RanBP2
#Genetics

Nathalie J Arhel @arhelnathalie.bsky.social · 10d

RANBP2 is a major susceptibility factor in Acute Necrotizing Encephalopathy. But is it a single protein, or are there other isoforms with distinct roles we should be studying?
@sdesgraupes.bsky.social @aneinternational.bsky.social @irim-life.bsky.social
www.sciencedirect.com/science/arti...

Unravelling the diversity of RANBP2: protein isoforms and implications for cellular function and human disease

RANBP2 (also known as Nup358) is the largest nucleoporin of the nuclear pore complex (NPC), where it constitutes the main component of the cytoplasmic…

www.sciencedirect.com

Reposted by ANE International

Alt CDC (they/them) @altcdc.altgov.info · 13d

5/
A really bad form of this is acute necrotizing encephalopathy, leading to literal brain damage 🧠
37 kids got this - from flu
And the worst bit is only 16% of the kids with flu-related encephalopathy who could get a flu shot had actually gotten one
GET 👏 YOUR 👏 FLU 👏 SHOT

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Reposted by ANE International

Lucia Ruggiero @lruggiero.bsky.social · 13d

Pediatric Influenza-Associated Encephalopathy and Acute Necrotizing Encephalopathy — United States, 2024–25 Influenza Season | MMWR
www.cdc.gov/mmwr/volumes...

Pediatric Influenza-Associated Encephalopathy ...

This report describes 109 U.S. cases of pediatric influenza-associated encephalopathy during the 2024–25 flu season – a high-severity season.

www.cdc.gov

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ANE International @aneinternational.bsky.social · 13d

We know first hand the severity of influenza. #ANEawareness is crucial. Thankyou for sharing.

ANE International @aneinternational.bsky.social · 13d

#influenza #AcuteNecrotizingEncephalopathy
www.nbcnews.com/health/healt...

More kids are severely ill or dying from the flu, CDC reports

As fewer children get their flu shots, cases of a rare, severe complication are rising. Last season, the U.S. experienced the highest number of pediatric flu deaths in 15 years.

www.nbcnews.com

Reposted by ANE International

J. Offir, PhD @joffirphd.bsky.social · 26d

Acute necrotizing encephalopathy is a rare but incredibly serious complication of infections like flu & covid. It often causes severe disability or death. Please get your kids their covid & flu vaccines; the families reported on in this story have to live w/ regret.

www.nytimes.com/2025/09/12/h...

Rare but Serious Complication Shows Flu’s Potential Harm

www.nytimes.com

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ANE International @aneinternational.bsky.social · Aug 29

👏👏#ANEawareness

Reposted by ANE International

ingohelbig.bsky.social @ingohelbig.bsky.social · Aug 28

Influenza and acute necrotizing encephalopathy – the genetic dimension

ANE. A rare complication with hidden genetic clues. Imagine a healthy child who goes to bed with a fever and wakes up unable to recognize their parents, slipping rapidly into coma. This is the terrifying course of acute…

Influenza and acute necrotizing encephalopathy – the genetic dimension

ANE. A rare complication with hidden genetic clues. Imagine a healthy child who goes to bed with a fever and wakes up unable to recognize their parents, slipping rapidly into coma. This is the terrifying course of acute necrotizing encephalopathy (ANE), one of the most severe neurological complications of influenza. In a recent study, children with influenza who developed ANE showed an unexpected pattern: nearly half of those tested carried genetic variants that might predispose them to this devastating complication.

epilepsygenetics.blog

ANE International @aneinternational.bsky.social · Aug 20

1️⃣ ANE while rare, is extremely serious, it can be deadly within a short period of time.
2️⃣ Most children with ANE were previously healthy.
3️⃣ Most of those with ANE & nearly all of those who died had not received the flu vaccine that season."

#influenza #vaccineswork #acutenecrotizingencephalopathy

CNN @cnn.com · Aug 19

A new study in JAMA has examined a rare but severe complication that can occur in children who contract the flu. This complication, called acute necrotizing encephalopathy, or ANE, carries a mortality rate of 27% despite intensive care and treatment, according to the new research. cnn.it/4lzElLI

ANE International @aneinternational.bsky.social · Aug 20

Thank you for sharing and raising awareness of this devastating complication. #ANEawareness
www.aneinternational.org

ANE International @aneinternational.bsky.social · Aug 15

👶Jasper was a happy, thriving 11 month old.
Then, an unknown virus triggered ANE.
📖 In this new story, Jasper's mother shares their experience & captures the devastating speed & impact of #AcuteNecrotizingEncephalopathy.
Read Here➡️ aneinternational.org/jasper/
#PedsICU #medicalemergency #virus

Reposted by ANE International

mtfamilies4vax.bsky.social @mtfamilies4vax.bsky.social · Aug 9

“I felt like I was robbed, we were robbed, of the opportunity to protect our children.”

Zach lost his daughter to influenza before the vaccine was recommended for all kids. If you’re a parent here’s what he has to say. youtu.be/5zBrARHsayE?... #NIAM2025

Why it's not "just the flu."

YouTube video by Voices for Vaccines

youtu.be

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Reposted by ANE International

CIDRAP @cidrap.bsky.social · Aug 5

Influenza, not Tamiflu, may raise risk of neuropsychiatric events in kids

Treatment with oseltamivir was associated with an approximately 50% reduction in the incidence of serious neuropsychiatric events.

www.cidrap.umn.edu/i...

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ANE International @aneinternational.bsky.social · Aug 5

🎥 In this expert talk, Dr. Ming Lim, Head of Children’s Neuroscience at Evelina London Children’s Hospital and King’s College London, breaks down the science behind ANE—and explains why early recognition and genetic testing matter.
#medsky #genetics #ANEawareness

m.youtube.com/watch?v=edV0...

Acute Necrotising Encephalopathy in Childhood: Genetic vs Sporadic | Dr. Ming Lim at ANEmone 2025

YouTube video by ANE International

m.youtube.com

ANE International @aneinternational.bsky.social · Aug 5

We certainly appreciated this work! 👏👏👏

ANE International @aneinternational.bsky.social · Aug 5

#ANEawareness
#AcuteNecrotizingEncephalopathy

Contemporary Pediatrics @contemppeds.bsky.social · Aug 5

In a new Q+A interview, Andrew Silverman, MD, MHS, Keith Van Haren MD, MD, and Molly Wilson-Murphy, MD, provide a deep dive into #influenza-associated acute necrotizing encephalopathy ( #ANE ). #Medsky #Pedsky

Read the full discussion here: www.contemporarypediatrics.com/view/q-a-a-d...

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ANE International @aneinternational.bsky.social · Aug 5

📌 We’ve laid out the facts. Now, we share another experience with #AcuteNecrotizingEncephalopathy (ANE)—because no two journeys are the same.

📖 One name. Many paths. Here's one more.
Read here ➡️ aneinternational.org/meredith/

#ANEawareness #i̇nfluenza #covid #RSV #virus #acquiredbraininjury #HHSV

ANE International @aneinternational.bsky.social · Aug 4

#AcuteNecrotizingEncephalopathy (ANE) may be the shared diagnosis—but every story unfolds uniquely.
🫶❤️📖 By sharing these diverse paths, we deepen awareness. One story at a time.

#ANEawareness #i̇nfluenza #VaccinePreventableDisease #virus #acquiredbraininury

aneinternational.org/stories/aust...

Reposted by ANE International

Samir S. Shah @samirshahmd.bsky.social · Aug 3

Two major points on influenza-associated acute necrotizing encephalopathy

- High mortality (27%)
- Most affected children were unvaccinated & did not have major comorbid conditions

#PedSky #IDSky

JAMA @jama.com · Aug 3

#Influenza-associated acute necrotizing encephalopathy in US children during the 2023-2024 and 2024-2025 influenza seasons showed high morbidity and mortality.

ja.ma/4oinX4Q #MedSky #PedSky

Figure 1. Neuroimaging Findings of Children With Influenza-Associated Necrotizing Encephalopathy

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ANE International @aneinternational.bsky.social · Aug 3

📋 We've shared the facts. Now, it’s time to meet the voices of lived reality.
#AcuteNecrotizingEncephalopathy isn’t just numbers—it’s real people, real families, and stories that deserve to be heard.

#ANEawareness #i̇nfluenza #RSV #covid #VPD

Video ➡️ aneinternational.org/grayson/

ANE International @aneinternational.bsky.social · Aug 2

Thanks so much Kevin, we really appreciate you helping us to raise awareness. 👏 More information is on our website - www.aneinternational.org #ANEawareness

ANE International | Acute Necrotizing Encephalopathy - Information & Support for Patients & Carers.