Adolfo Poma
@apoma.bsky.social
GōMartini 3 developer. 🇵🇪 Dad. Fascinated by how pathogens interact with cells.
🌐 http://pomalab.ippt.pan.pl/web/
🌐 http://pomalab.ippt.pan.pl/web/
Pinned
Adolfo Poma
@apoma.bsky.social
· Sep 7
Today our team member @fcofas.bsky.social is attending this @cecamevents.bsky.social organised in Sardegna: The Dual Nature of Glycans in Protein-Protein Interactions: Bridging Computational and Experimental Insights.
Thanks to @ncn.gov.pl for this great support!
Thanks to @ncn.gov.pl for this great support!
Reposted by Adolfo Poma
The Frankfurt Institute for Advanced Studies (FIAS) and the newly funded Cluster of Excellence SCALE are seeking several Independent Research Group Leaders to drive theoretical and computational research in molecular and cellular life science.
fias.institute/de/das-fias/...
fias.institute/de/das-fias/...
Independent Research Group Leaders (f/m/d) SCALE / FIAS
fias.institute
December 5, 2025 at 5:30 PM
The Frankfurt Institute for Advanced Studies (FIAS) and the newly funded Cluster of Excellence SCALE are seeking several Independent Research Group Leaders to drive theoretical and computational research in molecular and cellular life science.
fias.institute/de/das-fias/...
fias.institute/de/das-fias/...
Reposted by Adolfo Poma
Discussing my personal experiences navigating neurodiversity in academia, and what worked for me to cope better in my latest column for EMBO Reports. Please share with anyone who might find this useful/helpful. You are not alone.
www.embopress.org/doi/full/10....
www.embopress.org/doi/full/10....
A personal journey through academia as a neurodiverse scientist | EMBO reports
EMBO Press is an editorially independent publishing platform for the development of EMBO scientific publications.
www.embopress.org
November 24, 2025 at 5:43 PM
Discussing my personal experiences navigating neurodiversity in academia, and what worked for me to cope better in my latest column for EMBO Reports. Please share with anyone who might find this useful/helpful. You are not alone.
www.embopress.org/doi/full/10....
www.embopress.org/doi/full/10....
Reposted by Adolfo Poma
Happy to share the latest work from the lab, led by @mudgal17.bsky.social, in collaboration with the Weis lab @ethzurich.bsky.social.
How do nuclear membranes fuse during NPC assembly? We answer this question in our latest work, where we identify a new mechanism for membrane fusion… (1/13)
How do nuclear membranes fuse during NPC assembly? We answer this question in our latest work, where we identify a new mechanism for membrane fusion… (1/13)
July 23, 2025 at 11:40 AM
Happy to share the latest work from the lab, led by @mudgal17.bsky.social, in collaboration with the Weis lab @ethzurich.bsky.social.
How do nuclear membranes fuse during NPC assembly? We answer this question in our latest work, where we identify a new mechanism for membrane fusion… (1/13)
How do nuclear membranes fuse during NPC assembly? We answer this question in our latest work, where we identify a new mechanism for membrane fusion… (1/13)
🚀 New preprint!
We present an optimized contact map protocol for GōMartini 3 protein-assembly simulations.
🔹 Uses high-freq contacts from MD
🔹 Cuts contact sets by ~20–30% while keeping stability
🔹 Improves exploration of metastable states (e.g. SARS-CoV-2 spike)
Preprint: doi.org/10.1101/2025...
We present an optimized contact map protocol for GōMartini 3 protein-assembly simulations.
🔹 Uses high-freq contacts from MD
🔹 Cuts contact sets by ~20–30% while keeping stability
🔹 Improves exploration of metastable states (e.g. SARS-CoV-2 spike)
Preprint: doi.org/10.1101/2025...
November 16, 2025 at 9:30 PM
🚀 New preprint!
We present an optimized contact map protocol for GōMartini 3 protein-assembly simulations.
🔹 Uses high-freq contacts from MD
🔹 Cuts contact sets by ~20–30% while keeping stability
🔹 Improves exploration of metastable states (e.g. SARS-CoV-2 spike)
Preprint: doi.org/10.1101/2025...
We present an optimized contact map protocol for GōMartini 3 protein-assembly simulations.
🔹 Uses high-freq contacts from MD
🔹 Cuts contact sets by ~20–30% while keeping stability
🔹 Improves exploration of metastable states (e.g. SARS-CoV-2 spike)
Preprint: doi.org/10.1101/2025...
🚨 Preprint! Our work complements affinity studies for antibodies (Ab) design
🔹 Mechanostability as design criterion for Abs against viral escape.
🔹 Two-chain topology: H chain bears force, L chain reinforces via inter-chain contacts.
Great work by @fcofas.bsky.social www.biorxiv.org/cgi/content/...
🔹 Mechanostability as design criterion for Abs against viral escape.
🔹 Two-chain topology: H chain bears force, L chain reinforces via inter-chain contacts.
Great work by @fcofas.bsky.social www.biorxiv.org/cgi/content/...
A Comparative Nanomechanical Study of Antibody and Nanobody Binding to SARS-CoV-2 Variants
The receptor-binding domain of the SARS-CoV-2 spike protein is the principal target of neutralizing antibodies (Abs) and nanobodies (Nbs). Although their thermodynamic binding properties have been ext...
www.biorxiv.org
September 29, 2025 at 7:36 AM
🚨 Preprint! Our work complements affinity studies for antibodies (Ab) design
🔹 Mechanostability as design criterion for Abs against viral escape.
🔹 Two-chain topology: H chain bears force, L chain reinforces via inter-chain contacts.
Great work by @fcofas.bsky.social www.biorxiv.org/cgi/content/...
🔹 Mechanostability as design criterion for Abs against viral escape.
🔹 Two-chain topology: H chain bears force, L chain reinforces via inter-chain contacts.
Great work by @fcofas.bsky.social www.biorxiv.org/cgi/content/...
Today our team member @fcofas.bsky.social is attending this @cecamevents.bsky.social organised in Sardegna: The Dual Nature of Glycans in Protein-Protein Interactions: Bridging Computational and Experimental Insights.
Thanks to @ncn.gov.pl for this great support!
Thanks to @ncn.gov.pl for this great support!
September 7, 2025 at 6:08 PM
Today our team member @fcofas.bsky.social is attending this @cecamevents.bsky.social organised in Sardegna: The Dual Nature of Glycans in Protein-Protein Interactions: Bridging Computational and Experimental Insights.
Thanks to @ncn.gov.pl for this great support!
Thanks to @ncn.gov.pl for this great support!
🚨 "Evolution of the SARS-CoV-2 Spike Protein in Utilizing Host Transmembrane Serine Proteases"
🔬 How variants exploit more than just TMPRSS2 to enter cells.
Big thanks to @kpyrc.bsky.social team for this partnership 😎.
📄 Read: doi.org/10.1016/j.is... now in @cp-iscience.bsky.social
🔬 How variants exploit more than just TMPRSS2 to enter cells.
Big thanks to @kpyrc.bsky.social team for this partnership 😎.
📄 Read: doi.org/10.1016/j.is... now in @cp-iscience.bsky.social
August 25, 2025 at 9:14 PM
🚨 "Evolution of the SARS-CoV-2 Spike Protein in Utilizing Host Transmembrane Serine Proteases"
🔬 How variants exploit more than just TMPRSS2 to enter cells.
Big thanks to @kpyrc.bsky.social team for this partnership 😎.
📄 Read: doi.org/10.1016/j.is... now in @cp-iscience.bsky.social
🔬 How variants exploit more than just TMPRSS2 to enter cells.
Big thanks to @kpyrc.bsky.social team for this partnership 😎.
📄 Read: doi.org/10.1016/j.is... now in @cp-iscience.bsky.social