🧠 Alzheimer’s reversed in mice

A new study found that injecting nanoparticles can 'remind' the blood–brain barrier to function properly again, restoring normal brain activity in mice. Human trials could follow within years.

🔗 www.nature.com/articles/s41...

#SciComm #Alzheimers 🧪

Ideas aren't born in pristine originality. They explode when a familiar pattern is bent at just the right angle. And if that bothers you, ask yourself, would you rather clinging to a fantasy about being original or actually make something that people can't stop talking about?

youtu.be/jV09wDnQiTA

🎯"At the end of the day, our feelings do not tell us where they come from or why they exist. The only way to figure that out is to do some evolutionary psychology."

How David Hume split literature from philosophy

share.google/uRlpEYgdzNwW...

#philsky

My quote of the day

In the end, we will remember not the words of our enemies, but the silence of our friends.

Martin Luther King, Jr.

Excited to be heading to @Princeton @PrincetonSML to talk about my work on variational inference! Event details below:

csml.princeton.edu/events/batch...

🦎 Fossils rewriting snake and lizard evolution

Two new @nature.com studies reveal mosaic fossils showing how early lizards and snakes evolved. The findings uncover a Jurassic reptile mixing ancient and snake-like traits.

🔗 doi.org/10.1038/d415...

#SciComm #Paleontology 🧪

Evolutionary psychologists have claimed that "humans evolved heightened sensitivity to harm directed at women." This excellent (albeit at times gruesome) post makes the point that the ethnographic evidence does not really support this narrative.

Here's the core of recent content moderation questions relating to bsky. Or, why #JesseSingal is still here.

empirical contexts.

They do not depend upon our information (although our beliefs about frequencies do).

So when someone says that a process is #random, this can mean nothing more than ignorance of the details that would permit predicting the outcome

As a consequence, #probability changes when our information (or a model's information) changes. #Frequencies, in contrast, are facts about particular...

Equilibrium Matching (EqM): a generative modeling framework built from an equilibrium dynamics perspective

It simplifies and outperforms flow matching, where it exceeds Flow Matching in generation quality, supports optimization-based sampling, and solves downstream tasks naturally.

Feels good to see you back 😊

"No junk, no confusion" is an interesting expression that I've never heard before: mathoverflow.net/questions/16...

I keep a list of companies I don't want to work for, but those companies do hire people and make payroll. Am I self-sabotaging by refusing to work at those places? Will my friends disown me if I do take the money? What if it's companies that aren't wholly evil but have a bad internal track record?

Do AI reasoning models abstract and reason like humans?

New paper on this from my group:

arxiv.org/abs/2510.02125

🧵 1/10

"morality, the ghost of religion"

sysadmin, AI engineer, BI engineer

Meta open-sources OpenZL

A new data compression library and training tools to generator specialized compressors for structured data, achieving performance levels inaccessible to classic generic algorithms.

github.com/facebook/ope...

💭 AI can boost or block creativity, depending on task complexity

A new study found LLMs spark creativity in simple tasks but hinder it in complex ones. Constraining AI output helps restore balance.

🔗 www.nature.com/articles/s41...

#SciComm 🧪 #AI

highly recommend!

💡 Open science boosts research and growth

A new review found open access, open data, and open software make research faster, cheaper, and more innovative, but evidence is uneven across sectors.

🔗 doi.org/10.1098/rsos...

#SciComm 🧪 #OpenAccess

My friend @lkatfield.bsky.social has a book coming out that I think is essential reading for everyone. A starred review in Publisher's Weekly called it a "formidable debut ... a meticulous and unsettling revelation of a right-wing plan for a 'new old-fashioned world.'"