Check out the December 2025 issue of Trends in Neurosciences!
www.cell.com/issue/S0166-...

Featured content & more:
cell.com/trends/neuro...

Cover article: ‘Cracking the complexity of REM sleep’, by Yufan Dong & Danqian Liu
www.cell.com/trends/neuro...

Don't sleep on our December issue!

www.nature.com/neuro/volume...

Happening now ss3 ss4 dentate spikes, beta, category learning in freely moving 🐒

Rm 25a @10:45 to hear about first full cell assembly reactivation in sleep in primates (human or nonhuman), comparing rvn for newly-learned and old memoranda. Implications for memory linking, integration. @sabbaspoor.bsky.social and I would love your feedback! #sfn25 🧠🧪

Here are our contributions for #SFN2025 #SFN25, Sunday and Monday morning. Hope to see you there!

At SfN and interested in 'neuronal dynamics underlying memory'?? Come check out the nanosymposium (NANO011) that @catrinahacker.bsky.social and I are chairing tomorrow (Sunday) from 8-11:30am. So many awesome folks sharing their research, spanning work in rodents, NHPs, and humans!!

Research in primate brains has been essential for the development of brain-computer interfaces and artificial neural networks. New funding and policy changes put future such advances at risk, write Cory Miller, @movshon.bsky.social and Doris Tsao.

#neuroskyence

bit.ly/47MXYLH

Beta bursts mediate amygdala gating of hippocampal emotional encoding https://www.biorxiv.org/content/10.1101/2025.09.26.678792v1

The hippocampus is one of the most studied brain areas because of its major role in fundamental brain functions including learning, memory, and spatial navigation.

In a new #ScienceReview, researchers focus on the role of overlooked areas and circuits within the hippocampus. https://scim.ag/3VKRbMM

The new issue is out 👉https://www.cell.com/cell/current

On the cover, three articles from the Mesoscopic Brain Mapping Consortium published with Neuron and Developmental Cell shed light on the cell type diversity and their connectivity in mouse and primate brains.

This is an epic experiment and set of results bsky.app/profile/kari...

= massive labor of love, built over yrs of foundational work, made possible with the laudable contributions from international students @sabbaspoor.bsky.social (lead, now w/ @jordan-farrell.bsky.social) and @aymanaljishi.bsky.social, and with BRAIN Initiative NINDS + Whitehall Foundation funding.

The NEW assemblies showed greater drift during the task, associated with several ensemble/graph theoretic markers of isolatedness, as in @denisejcai.bsky.social . Again, day-old “RECENT” assemblies look like OLD. Even within CA1, laminar diffs a la Abbaspoor et al., 2024 drop with assembly age.

YES, both groups reactivated, and yes, during sharp-wave-ripples. But the OLD group had stronger reactivation, and actually, that was evident even after 1 day, in the RECENT group. That proved to be a theme.

After careful curation of single units from CA1 and connected structures, we identified cell assemblies - repeated patterns of synchronous firing (typically N~100, some approaching 300). Some assemblies were more active in NEW trials, others OLD. But did either or both groups reactivate in sleep?

We recorded wirelessly from high-density probes in freely-moving macaques as they learned item-context sequences. In the same session, they had to remember an OLD sequence, learned weeks earlier, and a NEW sequence learned that day. We came back the next day, too, calling the NEW sequence RECENT).

How does the brain integrate information from new experiences while preserving established memories? Have a look at our latest preprint,
"Experience reorganizes content-specific memory traces in macaques" 🧵
🧪🧠🤖👩‍🔬
www.biorxiv.org/content/10.1...