New paper out!
We show how mechanosensitive adherens junction proteins link actomyosin contractility to actin assembly using in vitro reconstitution.
Huge congrats to Aurélie Favarin, Rayan Said, & all authors!
In Science Advances: www.science.org/doi/10.1126/...
#actin #myosin #mechanobiology

We are very happy to share our new PrePrint: Myosin VI orchestrates estrogen-driven gene expression in breast
cancer cells. www.biorxiv.org/content/10.1...

We characterise how Myosin VI is a key regulator of the Estrogen Receptor. Perturbation of Myosin VI impedes ER functionality.

how cool is that? Congrats!!

we found that nuclear envelope rupture triggers rapid DIAPH3 formin influx to generate a actin mesh to prevent further chromatin leakage from damaged nuclei. thanks to Pitter Huesgen @degradomics.bsky.social and @cibss.bsky.social, @chrkam.bsky.social

Hi all, check out our new preprint where we uncover:"Regulation of YAP activity by nuclear G-actin binding", www.biorxiv.org/cgi/content/...
#actin #YAP/TAZ #transcription #nucleus with help from Sonja-Verena Albers
‪@archaellum.bsky.social‬

from our 'older' paper Baarlink et al. 2017, live imaging of a dividing mouse fibroblast stably expressing a shuttling chromobody detecting actin - showing nuclear actin filaments during postmitotic nuclear expansion and chromatin decompaction as well as simultaneous membrane dynamics

please re-post! we are looking for a PhD candidate:
www.uniklinik-freiburg.de/en/career/jo...

Very pleased to share the publication of our paper "Talin and vinculin combine their activities to trigger actin assembly" in Nature Commun. Congratulations Hong Wang for your great work ! Thanks to our team members, and the Grosse team.
Article here: www.nature.com/articles/s41...