Lightnews — Scholar-powered news

Reposted by Robert Grosse @ grosselab

The Francis Crick Institute @crick.ac.uk · 2d

We're now recruiting early career group leaders at the Crick to lead ambitious research programmes and explore bold scientific questions.

Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research.

Apply now ➡️ www.crick.ac.uk/careers-stud...

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Reposted by Robert Grosse @ grosselab

Pedro Beltrao @pedrobeltrao.bsky.social · 2d

new preprint: Ubiquitin is a protein modification linked with degradation but known to regulate other functions. Over 100k ubiquitination sites have been discovered and here we (@julianvangerwen.bsky.social + others) try to prioritize those most critical to the cell www.biorxiv.org/content/10.1...

The functional landscape of the human ubiquitinome

Protein ubiquitination regulates cell biology through diverse avenues, from quality control-linked protein degradation to signaling functions such as modulating protein-protein interactions and enzyme...

www.biorxiv.org

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Reposted by Robert Grosse @ grosselab

Barral Lab @barrallab.bsky.social · 2d

Looking for a PhD for 2026? We have 2 projects in collaboration with Clare Bennett (UCL) looking at macrophage metabolism in breast cancer. Check them out! @cruk-cityoflondon.bsky.social

www.colcc.ac.uk/2026-phd-pro...

crukradnet.colcc.ac.uk/phd-students...

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Reposted by Robert Grosse @ grosselab

University of Cambridge @cam.ac.uk · 4d

It is with great sadness that the University shares the news of the death of Professor Sir John Gurdon, founder of the @gurdoninstitute.bsky.social

Read our tribute to the visionary Nobel Laureate and watch an interview from 2012, just after he won: https://bit.ly/4mM8o3r

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Robert Grosse @ grosselab @grosselab.bsky.social · 3d

my favourite paper: genesdev.cshlp.org/content/25/9...

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Reposted by Robert Grosse @ grosselab

Max Planck Institute for the Science of Light (MPL) @mpi-scienceoflight.bsky.social · 3d

With deep sadness, we share that Prof. Jochen Guck, Director at the Max Planck Institute for the Science of Light passed away on October 3. His visionary work bridged physics and medicine. We have lost a brilliant scientist and dear friend.

mpl.mpg.de/news/article...
@fau.de

📸 Stephan Spangenberg

Professor Jochen Guck, Director at the Max Planck Institute for the Science of Light (MPL), He headed the division “Cell Physics” at MPL and the Max-Planck-Zentrum für Physik und Medizin (MPZPM).

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Reposted by Robert Grosse @ grosselab

EMBO @embo.org · 4d

Learn all things #cytoskeleton #research in an interdisciplinary environment at EMBO Workshop "Structure and Function of the Cytoskeleton" in Paris, FR, 7–10 April 2026.

Deadline: 20 December 2025

https://meetings.embo.org/event/26-cytoskeleton
#EMBOCytoskeletalFunction #EMBOevents #conference 🧪

Structure and Function of the Cytoskeleton

The cytoskeleton, a dynamic and intricate network of protein filaments, is found within the cytoplasm of all cells, from bacteria and archaea to complex eukaryotes. This essential cellular component …

meetings.embo.org

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Reposted by Robert Grosse @ grosselab

Journal of Cell Science @jcellsci.bsky.social · 8d

Mario Ledesma-Terrón, Diego Pérez-Dones, David Míguez and colleagues @cbm-csic-uam.bsky.social @ifimacuam.bsky.social present OSCAR, a framework to quantify 3D stacks with high cellular density.
journals.biologists.com/jcs/article-...

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Reposted by Robert Grosse @ grosselab

The Francis Crick Institute @crick.ac.uk · 9d

Long dismissed as genetic junk, the dark genome is stepping into the spotlight.

@rogerhighfield.bsky.social speaks to George Kassiotis and Samra Turajlic @turajliclab.bsky.social about how ancient viral remnants and rogue DNA impact evolution and disease.

www.crick.ac.uk/news/2025-10...

A message from the dark genome

Long dismissed as genetic junk, the dark genome is stepping into the spotlight, revealing how ancient viralremnants and rogue DNA elements impact evolution and disease.

www.crick.ac.uk

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Reposted by Robert Grosse @ grosselab

Proceedings of the National Academy of Sciences @pnas.org · 9d

Jackson Pollock’s painting, Number 1A, 1948, includes a vivid blue pigment of unknown origin. Laser spectroscopy identifies the paint as metal-based manganese blue, a distinctive color patented in 1935 and no longer available. In PNAS: www.pnas.org/doi/10.1073/...

Detail from Jackson Pollock's Number 1A
CREDIT: CC BY-NC-SA 2.0 PJMixer

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Reposted by Robert Grosse @ grosselab

The Francis Crick Institute @crick.ac.uk · 10d

We're looking for clinicians who are passionate about research to join our 3-year fully funded clinical PhD programme. 🔬🩺

Apply by 14 November 2025. 👇

www.crick.ac.uk/careers-stud...

Doctoral clinical fellows

The Crick's clinical PhD programme.

www.crick.ac.uk

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Reposted by Robert Grosse @ grosselab

Journal of Cell Science @jcellsci.bsky.social · 11d

We're still accepting submissions for our next special issue:
Cell Biology of the Nucleus
Guest edited by @abbybuch.bsky.social and Megan King @luskinglab.bsky.social.
Submission deadline: 3 November
journals.biologists.com/jcs/pages/nu...

#cellbiology #nucleus #notforprofit #freetopublish

Promotional graphic for a special issue of Journal of Cell Science titled 'Cell Biology of the Nucleus.' Guest Editor: Abby Buchwalter. Submission deadline: 3 November 2025. The image features a stylized cell with a bright pink, heart-shaped nucleus on a black background. Text includes a call for papers.

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Robert Grosse @ grosselab @grosselab.bsky.social · 11d

interesting!

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Reposted by Robert Grosse @ grosselab

Shiori Iida @shiori-iida.bsky.social · Aug 29

One more movie!
Using the RL algorithm (from pnas.org/doi/10.1073/...),
@masaashimazoe.bsky.social analyzed our nucleosome tracking data and classified them by their mobility.
Hotter color = faster motion (Slow🔵→ 🟢 → 🟡 → 🟠 Fast)

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Reposted by Robert Grosse @ grosselab

Pombo-GarciaLab @pombo-garcialab.bsky.social · Sep 6

🚨 We are hiring a #postdoc in Quantitative Cell Biology/Biochemistry. Join us if you are interested in using super-resolution STED & cryoET to uncover self-organization dynamics of epithelial cell interfaces & glycobiology collaboration with WuLab
zurl.co/aTGq7

About The Rosalind Franklin Institute - Rosalind Franklin Institute

The Rosalind Franklin Institute is a new national institute, announced in 2017 by the UK government, dedicated to bringing about transformative changes in life science through interdisciplinary resear...

zurl.co

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Reposted by Robert Grosse @ grosselab

Felix Campelo @felixmendu.bsky.social · 12d

Join us for the first @embo.org meeting on Intracellular mechanics and organelle mechanobiology! Registrations are open, submit your abstract by November 14: we have plenty of slots for short talks! #EMBOMechanobio

Felix Campelo @felixmendu.bsky.social · Jul 4

Announcing a new @embo.org Workshop on "Intracellular mechanics and organelle mechanobiology" that we are organizing with Michael Krieg and Verena Ruprecht at @icfo.eu (Barcelona) on 16-20 February, 2026. Please, repost and spread the word! 🙏 #EMBOmechanobio

meetings.embo.org/event/26-org...

Intracellular mechanics and organelle mechanobiology

Mechanobiology is an interdisciplinary field that emerges at the cross-section of biology, physics and engineering. It aims to understand how living cells, tissues and animals sense and respond to me…

meetings.embo.org

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Robert Grosse @ grosselab @grosselab.bsky.social · 15d

thanks!!

Robert Grosse @ grosselab @grosselab.bsky.social · 15d

#FluorescenceFriday : happy MitoFriday

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Reposted by Robert Grosse @ grosselab

Christophe 🔬 L @christlet.bsky.social · 15d

#FluorescenceFriday: getting ready for #GEF25, playing with Ciarán's stunning ExM data

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Robert Grosse @ grosselab @grosselab.bsky.social · 15d

yes, the probe sas very helpful and ist works amazingly well for live cell imaging, almost no bleaching :)

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Reposted by Robert Grosse @ grosselab

Connor Rogerson @doctorconnor.bsky.social · 16d

We have space for two postdoctoral fellows in the Taipale Lab at the @sangerinstitute.bsky.social. This is a core-funded open position! Come with your ideas and interests and we can develop a project together.

sanger.wd103.myworkdayjobs.com/en-US/Wellco...

Postdoctoral Fellow - Gene Regulation and Functional Genomics

Do you want to help us improve human health and understand life on Earth? Make your mark by shaping the future to enable or deliver life-changing science to solve some of humanity’s greatest challenge...

sanger.wd103.myworkdayjobs.com

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Reposted by Robert Grosse @ grosselab

Paul & Virginie - Centriole Lab @centriolelab.bsky.social · 26d

Be our new colleague! 🎉
The Dept of Molecular and Cellular Biology at the University of Geneva is hiring an Assistant Professor or Associate Professor.

👉 More details here: lnkd.in/e8Z9eAm4
👉 Our department: mocel.unige.ch

Please feel free to share this opportunity with your network.

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Reposted by Robert Grosse @ grosselab

Manuel Thery @manuelthery.bsky.social · Sep 9

Which city is the best for Cytoskeleton research?
Dresden? Barcelona? Cambridge ? Noooo ... you all know its Paris, right? 😎
Registering to the annual meeting on Friday 14th of November is now open:
pcd2025.sciencesconf.org
Keynote speeches by @carter-lab.bsky.social and Verena Ruprecht !

Paris Cytoskeleton Day 2025 - Sciencesconf.org

pcd2025.sciencesconf.org

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Reposted by Robert Grosse @ grosselab

John Lees @bacpop.org · 24d

The EMBL PhD programme is open until 13th October (entry ~Sep 2026):
www.embl.org/about/info/e...

We have three positions in microbial genomics at EMBL-EBI, including one in my group. Please do apply, or if you know anyone that would be interested pass on to them

EMBL International PhD Programme – Unique in the world and waiting for you!

www.embl.org

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Reposted by Robert Grosse @ grosselab

John Ngo @johntngo.bsky.social · 19d

🚀 Our new paper is out @natmethods.nature.com!

Kuffer & Marzilli engineered conditionally stable MS2 & PP7 coat proteins (dMCP & dPCP) that degrade unless bound to RNA, enabling ultra–low-background, single-mRNA imaging in live cells.

🔗 www.nature.com/articles/s41...
🧬 www.addgene.org/John_Ngo/

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