Staphylococci are the most common cause of orthopaedic device-related infections (ODRIs), with Staphylococcus aureus responsible for a third or more of cases. This prospective clinical and laboratory ...

How Staphylococcus aureus Plays Dirty in Orthopaedic Device Infections

Welcome to Pascoe Lab global Pathogen Genomics & evolution

Introduction. The global spread of extended-spectrum cephalosporinase-producing Escherichia coli (producing extended-spectrum β-lactamase or plasmid-borne AmpC, hereafter ESC-Ec) is a major public hea...

Abstract. The diffusible toxin ColIb produced by Salmonella enterica serovar Typhimurium SL1344 is a potent inhibitor of Escherichia coli growth. To identi

Identifying genetic variants associated with bacterial phenotypes, such as virulence, host preference and antimicrobial resistance, has great potential for a better understanding of the mechanisms inv...

Why now? Campylobacter infections are on the rise globally, with increasing levels of antimicrobial resistance (AMR) making treatment more challenging. As the world’s most common bacterial cause of gastroenteritis, Campylobacter poses a growing public health threat, yet effective interventions remain limited. There is an urgent need for research into novel and sustainable strategies to mitigate its impact—spanning genomics, surveillance, food safety, and public health interventions.

Heredity - Horizontal transfer of accessory chromosomes in fungi – a regulated process for exchange of genetic material?

Background Maintaining gut health is a persistent and unresolved challenge in the poultry industry. Given the critical role of gut health in chicken performance and welfare, there is a pressing need t...