Imagine if the blood type of a donor organ no longer mattered.

Researchers from Canada and China used glycoenzymes FpGalNAc deacetylase and FpGalactosaminidase to "convert" a Type-A donor kidney into a Universal organ by removing unwanted A-antigens. Great glyco-work!! #glycotime

rdcu.be/eJ4Bc

☀️ Your Brain Needs a Tan, Too! 🧠

Are you coming to San Diego for the SFG Annual Meeting (Nov 9–12), so why not make the most of it?

Jump straight into the focused, high-impact Workshops! Sign up today to take advantage of all the #glycotime goodness
www.glycobiology.org/annual-meeting

Think DNA and proteins are the whole story? Think again! 🤯 The Flynn lab just found a powerful new way to map out glycoRNAs using their super-sensitive rPAL-seq method. This innovative technique revealed glycoRNA patterns on snRNAs/snoRNAs and extracellular vesicles. #CellBiology #glycotime 🧪

We’re excited to invite you to the @giaglyco.bsky.social GIA2025 Symposium on Thursday and Friday, November 6–7. Registration is free and the event will take place in person and virtually for those joining online. glyco-alberta.ca/gia2025/ Come get the latest #Glycogang swag!

The key to cancer's sugar shield (O-GalNAc glycosylation) is the enzyme GalE! 🎯 Ben Schuman's lab just unveiled powerful new GlaE inhibitors of using a new fragment screening + structure-based design approach, opening new paths for oncology therapeutics! #ChemicalBiology #DrugDesign #glycotime 🧪

Using deuterium and neutron crystallography, the Imberty lab just cracked the atomic-level structure of the P. aeruginosa lectin, LecA, binding human sugars! 🧪

This structural insight is vital for designing new drugs. Great work, @anneimb.bsky.social team!

#DrugDesign #glycotime

I’m trying to remember what story Harry was telling to make him laugh like that 🤣🤣

Awesome to see GlyCounter at work!

www.biorxiv.org/content/10.1...

The world of biology is full of specific rules... but Glycosyltransferases (GTs) are here to shake things up! 🧪

GTs add sugar chains to proteins and lipids (glycosylation).

Understanding GT substrate selectivity is key to engineering enzymes with improved properties for industrial use! #glycotime

The BioFGREAT team is always excited about new tools to streamline protein design workflows. Looking forward to checking out ProteinDJ! 🚀🧪

Did you know the extracellular matrix has a sweet side? New research from the Robert Haltiwanger at @universityofga.bsky.social is shaking up what we know about Marfan syndrome! #glycotime #biochemistry #humanhealth

- Journal of Biological Chemistry www.jbc.org/article/S002...

Meet the BioF:GREAT Team at The Society for Glycobiology's Annual Meeting in San Diego this November and be part of the future of glycoscience! Register for SfGlycobiology here:

www.glycobiology.org/annual-meeting

See you there!
#SfGlycobiology #glycotime #biotech #glycotime #glycosylation

The team at BioF:GREAT is always on the lookout for new protein design models that care about more than just the backbone! We are excited to try the new RFdiffusion3 (RFD3)! 🚀 New preprint from David Baker!🚀 🧪 #ProteinDesign #DeepLearning #ComputationalBiology

www.biorxiv.org/content/10.1...

🍭 Glycans are biology’s sugar code—super complex, super important. Thanks to AlphaFold3, we can now model their interactions with proteins! 🧪 Our new workflow unlocks fresh ways to explore immunity, infection & disease.

doi.org/10.1093/glyc...

#BioFGREAT #NSF #glycotime

Breaking news: Richard Cummings created a Periodic Table of Monosaccharides! So next time someone says “sugar is simple,” just casually drop that there’s a whole periodic table for them! #glycotime 🧪
academic.oup.com/glycob/artic...

Super excited by our new #glycotime preprint! A long-term project from my group with awesome collaborator @elisafadda.bsky.social

Regulation of N-glycosylation efficiency by eukaryotic oligosaccharyltransferase www.biorxiv.org/content/10.1...

thread below 👇

We’re proud to support our community through our published work and gifting profits back into the Society to fund their charitable aims and now we’re seeking experts in their field to join our international editorial boards, find out more and apply: www.biochemistry.org/about-us/new...

In case you missed it: DNA miniprep columns are an equivalent replacement for the classic proteomics suspension-traps, and 10x cheaper.
$5 a sample in prep just doesn't scale so it's either SP3 or this approach.
pubs.rsc.org/en/content/a...

🧪

🍭 Glycans are biology’s sugar code—super complex, super important. Thanks to AlphaFold3, we can now model their interactions with proteins! 🧪 Our new workflow unlocks fresh ways to explore immunity, infection & disease.

doi.org/10.1093/glyc...

#BioFGREAT #NSF #glycotime

The Kannan Lab at UGA, with BioF:GREAT, has shown that the “dark kinome” still hides secrets 🔦 Enter DCLK3—a kinase with neuroprotective potential. We found it self-regulates in a brand-new way, and tags Tau as a substrate. A fresh spark for neurodegenerative research! 🧪

#BioFGREAT #NSF #kinase