Bettina Böttcher
@boettchercryoem.bsky.social
190 followers 160 following 5 posts
scientist in #cryoem and professor @uni-wuerzburg.de
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boettchercryoem.bsky.social
Very cool work by the Schindelin [email protected] @uni-wuerzburg.de. Very excited to see this preprint. Happy to have contribute some #cryoEM
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biorxivpreprint.bsky.social
Cryo-EM Structures of Higher Order Gephyrin OligomersReveal Principles of Inhibitory Postsynaptic Scaffold Organization https://www.biorxiv.org/content/10.1101/2025.09.01.673457v1
Reposted by Bettina Böttcher
ibbacnr.bsky.social
Erice Structural Biology Course 2026 (29 May–6 Jun): apply! Train in Cryo-EM, Cryo-ET & ML to study macromolecular assemblies in cells. Hands-on + theory for next-gen structural cell biology.
🔗 erice2026.azuleon.org/application....
#CryoEM #CryoET #MachineLearning #StructuralBiology #CellBiology
International School of Crystallography :: APPLICATION
The International School of Crystallography - held in Erice, Italy, since 1974
erice2026.azuleon.org
boettchercryoem.bsky.social
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We were very surprised to find out that the MscS-like channel YnaI does not tilt its paddle helices to open.... almost overlooked the huge pore in our cryo-EM maps
Very proud that this is finally out: rdcu.be/eB3FF
Well done, Vanessa @uni-wuerzburg.de
YnaI in the open and closed state
Reposted by Bettina Böttcher
biorxiv-biochem.bsky.social
SLC26A11 is an atypical solute carrier with dual transport-channel function mediating lysosomal sulfate transport https://www.biorxiv.org/content/10.1101/2025.08.17.670773v1
Reposted by Bettina Böttcher
uni-wuerzburg.de
🎉 Congratulations to @angelifriedmann.bsky.social‬ on receiving an @erc.europa.eu Proof of Concept grant! With his project “SulFex”, he is working on a new strategy for treating a specific form of lung cancer #ERCPoC 📷Andreas Heddergott go.uniwue.de/poc-grant-an...
Reposted by Bettina Böttcher
cryoempapers.bsky.social
Structure of lymphostatin, a large multi-functional virulence factor of pathogenic Escherichia coli pubmed.ncbi.nlm.nih.gov/40562750/ #cryoem
boettchercryoem.bsky.social
Our paper on Lymphostatin is now out (rdcu.be/etk2v). It shows #cryoEM structures of this huge virulence factor revealing amazing domain reorganisations.
Very enjoyable collaborating with the Stevens Lab in Edinburgh and the Boersch Lab in Jena to see how it gets into cells.
@uni-wuerzburg.de 🧪❄️
boettchercryoem.bsky.social
Very happy that this is now out. Cool collaboration with Weikert and Gmeiner group
#cryoem #gpcrs 🧪 @uni-wuerzburg.de @fau.de
cryoempapers.bsky.social
Discovery of a functionally selective serotonin receptor (5-HT1AR) agonist for the treatment of pain pubmed.ncbi.nlm.nih.gov/40531992/ #cryoem
Reposted by Bettina Böttcher
dfg.de
Die #Exzellenzcluster stehen fest: Heute hat die Exzellenzkommission 70 Projekte zur Förderung ausgewählt. 45 Cluster werden fortgesetzt, 25 neu eingerichtet. Die Förderung beginnt ab 1. Jan. 2026 für 7 Jahre, die Fördersumme beträgt insg. 539 Mio. €/Jahr. Die Liste: www.dfg.de/resource/blo... 1/3
Deutschlandkarte der Verteilung der Exzellenzcluster auf Bundesländer und Universitäten.
Reposted by Bettina Böttcher
uni-wuerzburg.de
Die Uni Würzburg unterstützt die Petition "Geht wählen – mit Verstand: #Demokratie braucht #Fakten"
Heute fand dazu ein Flashmob am RVZ statt - und 150 Personen folgten dem Ruf.
🗣️"Nur eine demokratische Gesellschaft schützt Forschungs- und Meinungsfreiheit", so Organisator Prof. Manfred Gessler.
Etwa 150 Personen folgten dem Aufruf zum Flashmob. (Bild: Jochen Kuper)
boettchercryoem.bsky.social
Our joined effort with the the Maric Lab @hmariclab.bsky.social @uniwuerzburg.bsky.social on how to aggregate capsids of Hepatitis B virus inside cells is now out in Elife doi.org/10.7554/eLif... . #cryoEM 🧪❄️🔬