Brian DePasquale
@briandepasquale.bsky.social
1.6K followers 390 following 43 posts
science. https://briandepasquale.github.io
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Reposted by Brian DePasquale
mehr.nz
"the quickest way to get a collaborator to return edits on your manuscript is to write down their affiliation wrong" (ancient academic proverb)
Reposted by Brian DePasquale
zamakany.bsky.social
Can one bring together Reinforcement learning and Drift Diffusion models to understand collective foraging ?

Congrads to Jonathan Marienhagen , Lisa Blum Moyse and Dominik Deffner on this new study. Very happy that I was part of this collaboration.

Preprint here: osf.io/preprints/ps...
Reposted by Brian DePasquale
Reposted by Brian DePasquale
dlevenstein.bsky.social
“NeuroAI should not remain limited to learning statistical relationships, but should also help in building mechanistic and causal models of neural activity. These models will incorporate biological properties of neural circuits, including cellular characteristics and network properties.”

💯💯💯
clopathlab.bsky.social
We were asked to write a commentary on NeuroAI for Nat. Rev. Neuro. with Sadra Sadeh, so here it is: www.nature.com/articles/s41...
www.nature.com
Reposted by Brian DePasquale
tuthill.bsky.social
Congrats to the 2025 cohort of McKnight Scholars!

www.mcknight.org/news-ideas/2...
Reposted by Brian DePasquale
neuroluci.bsky.social
How do brain circuits evolve? We started looking for some answers by using synapse-resolution cross-species comparative connectomics on an entire olfactory circuit 👇

bit.ly/44aVm9E
Reposted by Brian DePasquale
briandepasquale.bsky.social
Tired of your boring old DDM? Check out recent work by grad student @ryguy.io that introduces a *state-dependent* DDM using an underlying HMM. We find mice change their speed-accuracy strategy from trial to trial! Code provided! (in Julia of course!)
ryguy.io
🚨PREPRINT ALERT🚨

"A State–Dependent Drift Diffusion Model Reveals Mice Actively Explore A Speed–Accuracy Continuum During Decision-Making" is now available on biorxiv! Check it out below 👇

www.biorxiv.org/content/10.1...

In this work we find that mice are not just static mindless decision makers.
A State-Dependent Drift Diffusion Model Reveals Mice Actively Explore A Speed–Accuracy Continuum During Decision-Making
Understanding how animals shift between different decision-making strategies is critical for bridging normative models with naturalistic behavior. While drift diffusion models (DDMs) provide a powerfu...
www.biorxiv.org
Reposted by Brian DePasquale
itaiyanai.bsky.social
90% of doing science is being open to new ideas.
Reposted by Brian DePasquale
nicoadams.bsky.social
Unsurprising, but nevertheless tragic. Makes it very hard for integrators and multidisciplinarians to exist in academia. #academicsky
Reposted by Brian DePasquale
athenaakrami.bsky.social
Hivemind, what's the best approach/tool to aggregate neural data across sessions (and animals) in dimensionality reduction analyses, particularly when it's not known how overlapping the pool of neurons are over different sessions?
Reposted by Brian DePasquale
richardsever.bsky.social
"The core strategy is to slow NIH spending to generate surpluses...then use surpluses as justification for slashing the budget...unspent [$] won’t be because NIH doesn’t have good science to spend on [but] because the administration has blocked spending" donmoynihan.substack.com/p/the-nih-bu...
donmoynihan.substack.com
Reposted by Brian DePasquale
tyrellturing.bsky.social
Using pretrained vision-language models to align neural signals from different modalities:

arxiv.org/pdf/2407.14020

Cool stuff, though I would still love to see if we could align different neural modalities without the pretrained VLMs...

🧠📈 🧪 #NeuroAI
arxiv.org
Reposted by Brian DePasquale
p1sh.bsky.social
“Science is a smart, low cost investment. The costs of not investing in it are higher than the risk of doing so… talk to people about science.” - @kevinochsner.bsky.social makes his case to the field #sans2025
briandepasquale.bsky.social
Would love to be added. Developing StateSpaceDynamics.jl
Reposted by Brian DePasquale
hritz.bsky.social
Cool project led by Victor Geadah, fitting smoothly time-varying (and condition-varying) linear dynamical systems to neural activity.

arxiv.org/abs/2502.18347
screenshot of a figure from the paper. a linear dynamical system with time-varying inputs and dynamics reproduces mouse foraging behavior
Reposted by Brian DePasquale
neurovenki.bsky.social
I feel compelled to acknowledge the dread and dismay that many international students in the US are feeling at the moment - we see you, even if we feel rather powerless for now. Here's the very first visa stamp on my Indian passport ~40 years ago to come to UW Seattle for an MS in Bioengineering.
Page for passport showing a US student visa stamp from 1986
Reposted by Brian DePasquale
lipshutz.bsky.social
📣 Grad students and postdocs in computational and theoretical neuroscience: please consider applying for the 2025 Flatiron Institute Junior Theoretical Neuroscience Workshop! All expenses are covered. Apply by April 14. jtnworkshop2025.flatironinstitute.org
Reposted by Brian DePasquale
neurovium.bsky.social
@petersenpeter.bsky.social @jakhmack.bsky.social @sejdevries.bsky.social @bingbrunton.bsky.social @jeremymagland.bsky.social @briandepasquale.bsky.social @maryamshanechi.bsky.social
+others not on sky: David Kleinfeld , Tim Gardner, Maryam Shanechi, Carlos Ponce, Eli Schlizerman, Edgar Walker,...
neurovium.bsky.social
Arrived for #ODIN2025 @alleninstitute.bsky.social we have organized a fantastic lineup of speakers & participants:
Topics cover High Throughput Acquisitions & Data Integration, Building/Benchmarking AI Models, Multiscale Analyses & AI Models.
CompNeuro North Star!
alleninstitute.org/odin-symposi...
ODIN Symposium 2025 I Speakers
Preview the speakers and workshops below to gain further insight into conference programming.
alleninstitute.org