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John Tuthill @tuthill.bsky.social · 14h

legend

John Tuthill @tuthill.bsky.social · 14h

peak bloobs right now out in the glacier peak wilderness

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Institute of Neurobiology - UPR @neurobio-upr.bsky.social · 1d

Apply now!!! 🔥

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eLife @elife.bsky.social · 1d

1/ We’re delighted to hear that our Reviewing Editor, Shimon Sakaguchi, has been awarded the 2025 Nobel Prize in Physiology and Medicine today alongside colleagues Fred Ramsdell and Mary Brunkell: www.nobelprize.org

The official website of the Nobel Prize - NobelPrize.org

The Nobel Prize rewards science, humanism and peace efforts. This is one of the central concepts in the will of Alfred Nobel, and it also permeates the outreach activities that have been developed for...

www.nobelprize.org

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Janelia Research Campus @hhmijanelia.bsky.social · 1d

🪰 A team of researchers has unveiled the complete connectome of a male fruit fly central nervous system—a seamless map of all the neurons in the brain and nerve cord of a single male fruit fly and the millions of connections between them.
🔗 https://hhmi.news/4o3EJnk

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Julie Sedivy @juliesedivy.bsky.social · 8d

Important article at this point in history: "As much harm as a 40 percent cut to the NIH budget would have on scientific innovation, destroying the peer-evaluation system that decides what science is funded would be far worse." Indeed. It would be like doing away with criminal trial by jury.

John Tuthill @tuthill.bsky.social · 8d

This is the original story that i wrote about the topic for The Transmitter.
www.thetransmitter.org/craft-and-ca...

Fear and loathing on study section: Reviewing grant proposals while the system is burning

As grants are canceled, delayed and subject to general uncertainty, participating in study sections can feel futile. But it’s more important than ever.

www.thetransmitter.org

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John Tuthill @tuthill.bsky.social · 6d

thanks for speaking out @markhisted.org

Science and Freedom Alliance - SAFA @safa-science.bsky.social · 6d

Federal workers are speaking out on how the Trump regime is harming Americans:

"We stand here today at a moment of the greatest assault of our lifetimes on our freedoms. The US Constitution is being shredded... We are here to call on Congress to stand up and stop it."

youtu.be/uw1KwIBgrCw?...

Mark Histed, NIH Scientist *speaking in personal capacity

YouTube video by Civil Servants Coalition

youtu.be

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John Tuthill @tuthill.bsky.social · 6d

Congrats, Sweta! UBC is lucky to have recruited you and we're so happy to have you back in the PNW neighborhood.

Sweta Agrawal @hokuba.bsky.social · 6d

The Agrawal lab is moving! This January we will be setting up shop at #UBC in Vancouver, in the department of #Zoology! We are actively recruiting at all levels, especially masters and PhD students. These position are #funded! Please send anyone interested my way!

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Jeremy Berg @jeremymberg.bsky.social · 6d

The fiscal year is over.

So how was the NIH appropriation committed?

A long thread with institute by institute results about where the money went.

a white cat is sitting on a box with the words where written on it .

ALT: a white cat is sitting on a box with the words where written on it .

media.tenor.com

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John Tuthill @tuthill.bsky.social · 8d

still a nerd. also, i think the first article i ever wrote for publication was about your catering business for the phoenix.

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John Tuthill @tuthill.bsky.social · 8d

we made one! id make it open access but the royalties are paying for my country club membership

John Tuthill @tuthill.bsky.social · 8d

oh hi ja'dell! thanks

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John Tuthill @tuthill.bsky.social · 8d

This is the original story that i wrote about the topic for The Transmitter.
www.thetransmitter.org/craft-and-ca...

Fear and loathing on study section: Reviewing grant proposals while the system is burning

As grants are canceled, delayed and subject to general uncertainty, participating in study sections can feel futile. But it’s more important than ever.

www.thetransmitter.org

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John Tuthill @tuthill.bsky.social · 8d

also i got several emails pointing out that i failed to mention the impact of the NIH's new "forward-funding" scheme. i think this discussion didn't make it in for one of the reasons they are using it - it's not straightforward to explain and understand.

www.science.org/content/arti...

Odds of winning NIH grants plummet as new funding policy and spending delays bite

Funding multiyear grants up front will sharply cut number of investigators receiving awards

www.science.org

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John Tuthill @tuthill.bsky.social · 8d

thanks to @javierapfeld.bsky.social whose thread on microRNAs i had just read when the asked about the huntington's clinical trial bsky.app/profile/javi...

Javier Apfeld @javierapfeld.bsky.social · 13d

New cures feel sudden, but the seeds were planted decades ago by basic scientists.

Which seeds will turn into cures? Unpredictable looking forward, a straight line looking back. 🧪🧬 🧵

Huntington's disease successfully treated for first time

One of the most devastating diseases finally has a treatment that can slow its progression and transform lives, tearful doctors tell BBC.

www.bbc.com

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John Tuthill @tuthill.bsky.social · 8d

last week i spoke with the NPR show @onthemedia.bsky.social about what it feels like serving on an NIH grant review panel as the Trump administration works to defund and destroy US universities and biomedical research

www.wnycstudios.org/podcasts/otm...

Trump v. Tylenol. Plus, How Charlie Kirk Became a Martyr for the Christian Right. | On the Media | WNYC Studios

President Trump has declared that Tylenol should not be used during pregnancy. On this week’s On the Media, how funding cuts and disputed claims linking the drug to autism have sent s...

www.wnycstudios.org

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On the Media @onthemedia.bsky.social · 10d

📻👂On this week’s show: scientist @tuthill.bsky.social on what is being lost at the NIH, @joshuakeating.bsky.social on Trump’s ever expanding use of the word “terrorist.” And the always essential @matthewdtaylor.bsky.social on the martyrdom of Charlie Kirk. 👂📻 www.wnycstudios.org/podcasts/otm...

Trump v. Tylenol. Plus, How Charlie Kirk Became a Martyr for the Christian Right. | On the Media | WNYC Studios

President Trump has declared that Tylenol should not be used during pregnancy. On this week’s On the Media, how funding cuts and disputed claims linking the drug to autism have sent s...

www.wnycstudios.org

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Reposted by John Tuthill

Drug Monkey @drugmonkey.bsky.social · 10d

Whether you think limiting student visas to 4 years is a good or bad thing, please comment. Be heard.

Dr. Kat Napaaqtuk❄️ @napaaqtuk.bsky.social · 11d

Comment period ends on Monday for a proposed rule change that would terminate student visas after 4 years. It also puts limits on exchange visitors and reps of foreign media, and shortens the length of time at the end of the visa from 60 days to 30 days.

www.federalregister.gov/documents/20...

Establishing a Fixed Time Period of Admission and an Extension of Stay Procedure for Nonimmigrant Academic Students, Exchange Visitors, and Representatives of Foreign Information Media

Unlike most nonimmigrant classifications, which are admitted for a fixed time period, aliens in the F (academic student), J (exchange visitor), and most I (representatives of foreign information media...

www.federalregister.gov

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John Tuthill @tuthill.bsky.social · 11d

@chrisjdallmann.bsky.social pointed out that his paper was in review so long that it made it on twice! (preprint and final pub) totally worth it in my opinion

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eLife @elife.bsky.social · 12d

1/ Starting next year, @hhmi.org will require all authors to share their research as preprints under a CC BY 4.0 license as part of its new Immediate Access to Research policy.
buff.ly/NrHlEKD

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Jeremy Berg @jeremymberg.bsky.social · 12d

This paper does a great job with a "It's a Wonderful Life" scenario about NIH, supposing the consequences of the bottom 40% of the funding NIH grants never existed.

www.science.org/doi/10.1126/...

tl:dr The world would lose a lot, but directly and indirectly

What if NIH had been 40% smaller?

Replaying history with less NIH funding shows widespread impacts on drug-linked research

www.science.org

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Reposted by John Tuthill

Javier Apfeld @javierapfeld.bsky.social · 13d

New cures feel sudden, but the seeds were planted decades ago by basic scientists.

Which seeds will turn into cures? Unpredictable looking forward, a straight line looking back. 🧪🧬 🧵

Huntington's disease successfully treated for first time

One of the most devastating diseases finally has a treatment that can slow its progression and transform lives, tearful doctors tell BBC.

www.bbc.com

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Reposted by John Tuthill

Maria Paz Fernandez @mariadelapax.bsky.social · 15d

Ed Kravitz passed away yesterday.
He was a remarkable scientist and mentor- brilliant, curious, creative, and kind. I am grateful to have learned from him. His legacy will endure through his science and through the many people he inspired.

We will miss you, Ed.

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John Tuthill @tuthill.bsky.social · 18d

thanks for attending, ish. she passed!

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Daniel Kronauer @danielkronauer.bsky.social · 18d

The final version of our paper on how ants and possibly other insects use a crazy mechanism involving extensive transcriptional interference to regulate odorant receptor expression is now open access in my favorite journal, @currentbiology.bsky.social

authors.elsevier.com/sd/article/S...

ScienceDirect.com | Science, health and medical journals, full text articles and books.

authors.elsevier.com

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