Cascales Lab
@cascaleslab.bsky.social
570 followers 640 following 14 posts
How to specifically select a protein from one side of the membrane and to transport it on the other side ? That's what we love to understand. #T6SS #T9SS Location: CNRS - Aix-Marseille Université, France https://www.cascaleslab.fr
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Reposted by Cascales Lab
juliengiraud.bsky.social
Amazing science at the 2nd edition of the Secretion Days in Marseille 🌞 ! Huge thanks to all participants and to @archaellum.bsky.social for an outstanding opening talk. Looking forward to the next edition!
Reposted by Cascales Lab
pierresantucci.bsky.social
Extremely happy to share the fruit of a beautiful collaborative research study.

France 🇫🇷, Russia 🇷🇺 and USA 🇺🇸 teaming up to tackle a long-standing question in the TB field! 🧫🦠💊🥼🩺

Our latest Preprint on Pyrazinamide Mode of Action against M.tuberculosis is online! 👇👇👇

doi.org/10.1101/2025...
Pyrazinamide kills Mycobacterium tuberculosis via pH-driven weak-acid permeation and cytosolic acidification
Pyrazinamide (PZA) is a cornerstone drug in tuberculosis (TB) treatment with a strong bactericidal activity in vivo on both actively and non-replicating bacterial subpopulations. Yet the precise mode ...
doi.org
cascaleslab.bsky.social
We will have soon an Open position for a PhD thesis position to work on bacterial secretion systems !

Stay tuned !!
cascaleslab.bsky.social
Open position !!
Either at the Engineer or post-doctoral level, to work on filamentous phages. Collaboration between Laetitia Houot's group and Thierry Doan @thicoz.bsky.social.
To apply at the E level:
emploi.cnrs.fr/Offres/CDD/U...
To apply at the post-doc level:
emploi.cnrs.fr/Offres/CDD/U...
cascaleslab.bsky.social
This work complements the great work published in July on a T7SS effector with ADP ribose cyclase activity, by Jake Collauti and John Whitney
www.jbc.org/article/S002...
www.jbc.org
cascaleslab.bsky.social
We have an open engineer position to work on type IX secretion (T9SS), under the supervision of @doan_thierry (collab with HP Fierobe & A. Tolonen). 1-year contract, renewable up to 3.5 years. Please apply here or forward to anyone potentially interested:

emploi.cnrs.fr/Offres/CDD/U...
Portail Emploi CNRS - Offre d'emploi - Ingénieur d'Etude en Microbiologie (H/F)
emploi.cnrs.fr
cascaleslab.bsky.social
Le LISM (lism.imm.cnrs.fr) propose une mobilité en NOEMI pour travailler sur des assemblages de l'enveloppe bactérienne. Profil microbiologie, biologie moléculaire, avec une envie de faire de la biochimie, de la microscopie ou de la biologie cellulaire ! Rejoignez une unité dynamique !!
Welcome - LISM
The research topics of the LISM today remain centered on biological membranes and in particular membranes of Gram-negative bacteria. Since […]
lism.imm.cnrs.fr
Reposted by Cascales Lab
lowlab.bsky.social
Please RT. Post-doc opportunity alert! 💥 closing 5th May.. Come join our team (thelowlab.org) at Imperial, London, working on bacterial secretion systems. The position is funded by the Wellcome Trust.

For more details and to apply please see

www.imperial.ac.uk/jobs/search-...
cascaleslab.bsky.social
For those interested on the bacterial envelope and on secretion system: a 2-day symposium in Marseille ! Second edition of the Secretion Days !
juliengiraud.bsky.social
👉Don’t forget👈
📅 Secretion Days 2025 will take place on October 2–3 in Marseille 🌊
🎤Invited speaker : Sonja-Verena Albers; @archaellum.bsky.social
🆓 Free, spot are limited !
📥 Registration is open until May 15 via the following link:
🔗 docs.google.com/forms/d/e/1F...
Journées Sécrétion 2025
Contact: [email protected]
docs.google.com
cascaleslab.bsky.social
I understand now why you wanted to go to Compostelle ! 32 days to go (and how many beers ??) ! 😂
cascaleslab.bsky.social
You are a young researcher working on the bacterial cell envelope ? Don't miss this opportunity !!
maellepllt.bsky.social
The Journées Sécrétion are back!

2nd and 3rd October in Marseille

Keynote lecture by: @archaellum.bsky.social

Registration is open until May 15: forms.gle/2qxHntTktoxw...

Organized by Romé Voulhoux @lcbofficiel.bsky.social, @cascaleslab.bsky.social, Thierry Doan, @juliengiraud.bsky.social
cascaleslab.bsky.social
Great talk on RNA modifications in bacteria by Zeynep Baharoglu @zeynepbaharoglu.bsky.social at the weekly IMM seminar today !
cascaleslab.bsky.social
Thank you Nadia for the invitation and the organization ! It was great meeting so many colleagues ! See you soon !
cascaleslab.bsky.social

We have an open PhD position to work on bacterial secretion systems. Please RT, write us or apply through the CNRS job portal:
t.co/HxX23Od1oa
https://emploi.cnrs.fr/Offres/Doctorant/UMR7255-ERICAS-004/Default.aspx?lang=EN
t.co
cascaleslab.bsky.social
Happy to start a new social life on BlueSky !
Love from Marseille !