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Charles de Bock @charles-debock.bsky.social · Sep 5

Another great conversation on NUP98-rearranged #AML and the use of #Menin inhibitors. Plus some hot tips on how to measure cytotoxicity in co-culture systems and finally, how to pronounce #MEIS1. Listen below and subscribe where ever you get your podcasts from @hemasphere-journal.bsky.social

HemaSphere Journal @hemasphere-journal.bsky.social · Sep 5

🎙️New Episode!

Dr Charles de Bock hosts Prof Michel Zwaan and Prof Olaf Heidenreich, two co-authors from the 2025 HemaSphere Award - Top Cited: Biology paper "The MLL-Menin Interaction is a Therapeutic Vulnerability in NUP98-rearranged AML." 🎧 https://bit.ly/3HJbmr6

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HemaSphere Journal @hemasphere-journal.bsky.social · Aug 22

🎧REPLAY!

In this episode host Dr Charles de Bock discusses the role of mouse models in understanding leukemogenesis & hematopoiesis w/ Prof Richard Lock: https://bit.ly/40Ch3NP

Listen & enjoy casual, insightful discussions about #hematology research.

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NDLR_conference @ndlrconference.bsky.social · Aug 19

We are honoured to welcome Professor John D. Crispino, from
@stjude.bsky.social as speaker to #NDLR2026. John’s research focuses on mechanisms of #Leukemia development in children with Down syndrome and the malignant progression of #MyelodysplasticSyndrome and #MyeloproliferativeNeoplasms.

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Charles de Bock @charles-debock.bsky.social · Aug 15

Amazing work @bethpsaila.bsky.social and whilst platelets are certainly not my area, this is a paper that I will be digging into more. Congratulations to the entire team.

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Charles de Bock @charles-debock.bsky.social · Aug 5

Welcome back downunder!

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ISEH - International Society for Experimental Hematology @isehsociety.bsky.social · Jul 31

The NIC welcomes speakers Hanna Mikkola and Elizabeth Ng who will present their latest research on stem cell development and regeneration at the 20 August webinar on Human HSC Ontogeny. Register now www.iseh.org/ISEHWebinars

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Charles de Bock @charles-debock.bsky.social · Aug 1

Also - Super interested to hear from listeners. As host, I want to improve. Are the podcasts too long? too short? Need to have more clinical focus? More basic science focus? You want to know more about the technical side? Do I talk too fast? talk to slow? Are there topics you want to hear more on?

Charles de Bock @charles-debock.bsky.social · Aug 1

So the latest @hemasphere-journal.bsky.social Podcast is out! This time all about Metabolism. You can subscribe podcasts.apple.com/au/podcast/h... to get all the podcasts direct into your feed. Each is around 30 min, perfect for that commute to work.

HemaSphere Podcast

Medicine Podcast · Updated Monthly · HemaSphere is the official online, open access journal of the European Hematology Association (EHA). HemaSphere publishes exciting basic, translational, and clinic...

podcasts.apple.com

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Heather Lee @heatherjlee.bsky.social · Jul 28

I'm pleased to share that Leukemia have published our analysis of heterogeneous responses to hypomethylating agents #HMAs in Acute Myeloid Leukaemia #AML
www.nature.com/articles/s41...

Hypomethylating agents induce epigenetic and transcriptional heterogeneity with implications for acute myeloid leukemia cell self-renewal - Leukemia

Leukemia - Hypomethylating agents induce epigenetic and transcriptional heterogeneity with implications for acute myeloid leukemia cell self-renewal

www.nature.com

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Reposted by Charles de Bock

HemaSphere Journal @hemasphere-journal.bsky.social · Jun 18

This was very happy news to arrive to today! Thank you to our authors, reviewers, and readership for your continued support. We are glad to know that everyone's hard work is well-appreciated.

Jan Cools @jancools.bsky.social · Jun 18

Exciting to share the new impact factor of @hemasphere-journal.bsky.social, the #openaccess journal of the European Hematology Association (EHA).
The 2024 Journal Impact Factor is 14.6 - ranking as number 5 of 99 hematology journals (Source: Journal Citations Reports, Clarivate).

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HemaSphere Journal @hemasphere-journal.bsky.social · Jun 14

🚨Today! @ 15:45, MiCo room CORAL 6
We warmly invite you to the HemaSphere Scientific Session where we will dive into 3 of our exciting + cutting-edge biology publications. Hope to see you there!
🕰️: 15:45 - 16:45
📍: Room CORAL 6, #EHA2025
🎤: https://bit.ly/4koLwXk

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Reposted by Charles de Bock

Franziska Auer @franziskaauer.bsky.social · Jun 14

Don’t miss the second YERM Session on „New insights into clonal hematopoiesis“ at 10 o‘clock in Brown Hall 2!
#EHA2025 #YoungEHA #Hematology

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Charles de Bock @charles-debock.bsky.social · Jun 12

The team representing @kidscancerinst.bsky.social at #EHA2025 @hansenjk.bsky.social Faezeh Khalili, Jackie Huang, Yashna Walia

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HemaSphere Journal @hemasphere-journal.bsky.social · Jun 12

We are HemaSphere proud at #EHA2025, where 2 of our editors received special EHA awards! Congrats to Jan Cools, Ed in Chief, for the education & mentoring award; and to Mandy Lauw, Scientific Ed, for the YoungEHA award. Well deserved 👏 @jancools.bsky.social @mandylauw.bsky.social

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Charles de Bock @charles-debock.bsky.social · Jun 12

Honoured to have been a mentee of @jancools.bsky.social who is this years #EHA2025 Education and Mentoring award winner. Amazing and recognising his unwavering support for so many researchers!

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HemaSphere Journal @hemasphere-journal.bsky.social · Jun 12

Dr C de Bock hosts co-authors Dr F Fioredda & Dr E Papadaki to discuss Guidelines for treating neutropenias. Delve into the importance of international guidelines, challenges ➕ more. 🎧 https://bit.ly/42O9l4v.

Part 1: 2023 neutropenia Guidelines, diagnosis &management #2025HemaSphereAward winner 🏆

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Charles de Bock @charles-debock.bsky.social · Jun 12

Next up is Dr Hansen Kosasih @hansenjk.bsky.social looking at cis-regulome of AKR1C3 which activates super prodrug ACHM-025 and can eradicate T-ALL. He is speaking today at #EHA2025 molecular Hematopoiesis workshop. Plus poster PS1332 @kidscancerinst.bsky.social

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Charles de Bock @charles-debock.bsky.social · Jun 12

Where is the hemaSphere hut? Trying to find you👀

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Charles de Bock @charles-debock.bsky.social · Jun 12

Yes! I will look out for you!

Charles de Bock @charles-debock.bsky.social · Jun 12

For #EHA2025 our group has Phd Candidate Yashna Walia doing in vivo PDX dual gRNA screen of epigenetic regions looking into GR resistance. Check out Poster PS1334 @kidscancerinst.bsky.social

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Charles de Bock @charles-debock.bsky.social · Jun 12

Hello #EHA2025. Happy to be here with my group this week. Connecting with old friends and colleagues and making new friends this week. Let me know if you are around!

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Charles de Bock @charles-debock.bsky.social · Jun 12

Hello #EHA2025. Happy to be here with my group this week. Connecting with old friends and colleagues and making new friends this week. Let me know if you are around!

Charles de Bock @charles-debock.bsky.social · Jun 8

Looking forward to attend the #EHA2025 @hemasphere-journal.bsky.social sessions next week!

HemaSphere Journal @hemasphere-journal.bsky.social · Jun 7

Attention fundamental #hematology researchers: we warmly invite you to the HemaSphere Scientific Session at #EHA2025.
Dive into 3 of our exciting + cutting-edge biology publications. Mark your cals & see you there!
📆: Saturday, June 14
🕰️: 15:45 - 16:45
📍: MiCo, Room CORAL 6
🎤: https://bit.ly/4koLwXk

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Reposted by Charles de Bock

HemaSphere Journal @hemasphere-journal.bsky.social · May 29

Heading to #EHA2025 in Milan in 1.5(ish) weeks? HemaSphere has 2 exciting sessions on the program!
📌Peer Review Workshop: Fri 13 June, 13:30 - 15:00
💡Learn + master the peer review role/process
📌HemaSphere Scientific Session: Sat 14 June, 15:45 - 16:45
💡Dive into 3 of our cutting-edge biology papers

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Reposted by Charles de Bock

HemaSphere Journal @hemasphere-journal.bsky.social · May 16

This HemaTopic by Sci Ed C de Bock discusses using PDXs for testing leukemia therapies, focusing on PDX model maintenance, immunodeficient mice & standardized reporting for preclinical drug testing. It also ties in a recent HemaSphere podcast with Prof Richard Lock. See both👉

Patient‐derived xenografts: Practical considerations for preclinical drug testing

Click on the article title to read more.

bit.ly

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