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Chris Adami @chrisadami.bsky.social · 2d

Ummm.

Chris Adami @chrisadami.bsky.social · 3d

In the old German script the “ss” looks like “ff”

Reposted by Chris Adami

The Fake History Hunter @fakehistoryhunter.net · 4d

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Chris Adami @chrisadami.bsky.social · 8d

In case you were wondering...

Chris Adami @chrisadami.bsky.social · 8d

For those of you in the area: I will be part of the MSU Choir at this Saturday's performance at the Wharton Center of Jocelyn Hagen's "The Notebooks of Leonardo Da Vinci", which is a beautiful piece that marries orchestra, voice, and audiovisual effects. www.whartoncenter.com/events/detai...

The Planets | Wharton Center for Performing Arts

www.whartoncenter.com

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Chris Adami @chrisadami.bsky.social · 8d

That's been on my favorite list on YouTube for a while now!

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Chris Adami @chrisadami.bsky.social · 16d

1982-1986 Teaching Assistant
1986-1991 Research Assistant
1992-1995 Postdoc
1995-today Faculty
That's it. Never had another job.

Mueller, She Wrote @muellershewrote.com · 16d

Some jobs I’ve had:

1990: Telemarketer for Olan Mills
1991: McDonald’s
1992: Denny’s
1993: Olive Garden
1994: Super Crown Books
1995: Navy
1998: Denny’s again
1999: Sprint phone mall kiosk
2002: Guitar Center
2007: Hard Rock Hotel
2009: Veterans Affairs
2017: Podcaster

How about you?

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Chris Adami @chrisadami.bsky.social · 18d

Can confirm.

Nicholas Weaver @ncweaver.skerry-tech.com · 18d

Why is this horrible for Universities?

Just about everyone who isn't a citizen or green card holder already who's hired for a tenure track faculty position is hired through an H1B and then, after 3-5 years, applies for a green card.

This is literally "No more foreign professors can be hired"

Gergely Orosz @gergely.pragmaticengineer.com · 18d

Those on an H1B cannot return to the US from tomorrow (Sunday) unless paying $100K. This is an out-of-the blue presidential action. We’ll see software engineers stranded abroad.

One easy to predict outcome: those on US visas will travel less… for work, for conferences etc.

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Reposted by Chris Adami

Michael Baym @baym.lol · 18d

Immigrants, particularly on H1Bs, are the lifeblood of American innovation. If you wanted to hurt US competitiveness in the next century, I can think of few more effective ways than a move like this

Even when found illegal, the mere intent will have irreparably harmed our future

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Chris Adami @chrisadami.bsky.social · 19d

I think the point here is that these proteins do not carry out any function. If they were important than of course mutations to functionally important residues would matter. But these proteins do nothing at all. Yet, when mutated some mutations impair fitness.

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Reposted by Chris Adami

David Ho @davidho.bsky.social · 19d

Of all the stupid things that this regime has done, this is right up near the top. Postdoctoral researchers come to the US on H-1B visas. This will further destroy the US science enterprise. Stupid stupid stupid.

Trump administration to add $100,000 fee for H-1B visas

The Trump administration is targeting a visa widely used by tech companies and other employers to hire foreign workers.

www.cbsnews.com

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Chris Adami @chrisadami.bsky.social · 19d

The authors offer no clues. They used YFP, and some mutations appear to impair fitness, but not the ones that lead to misfolding. It's a mystery! It's like there is toxicity, but not due to what we usually assume (misfolded proteins).

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Chris Adami @chrisadami.bsky.social · 19d

This is really interesting! Mutations that affect a protein's foldability do not seem to impact org fitness if the protein is not important for function. But there *are* effects from mutations on those proteins (just not related to foldability). What are they due to??
www.biorxiv.org/content/10.1...

Collateral fitness effects of mutation are not commonly caused by protein misfolding

Mutations in coding sequences are often assumed to harm cells by destabilizing proteins and creating toxic misfolded species. Here we directly test how fitness scales with predicted folding stability....

www.biorxiv.org

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Chris Adami @chrisadami.bsky.social · 21d

My “I got the Covid vaccine” sticker from 2020 (which tells me which side is up on my laptop) got a bit ragged, so I replaced it.

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Chris Adami @chrisadami.bsky.social · 24d

My oldest brother and I were both left handed. He was forced to write with his right, I was in the first year where we were allowed to choose our hand. He suffered at school (and later in life, dead at 25). I prospered. Of course this is anecdotal, but I’ve been wondering ever since.

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Chris Adami @chrisadami.bsky.social · 24d

Hey, local news!

Lansing Facts @lansingmifacts.com · 24d

Dutch is a beautiful language

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Chris Adami @chrisadami.bsky.social · 27d

While I cannot say anything about this paper (as I haven't read it), I should point out that I reviewed several papers of the senior author, and they were not good. At all.

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Reposted by Chris Adami

Richard Lenski @relenski.bsky.social · 28d

With Jeff Barrick's return to #MSU, the #LTEE was restarted today after a short pause (frozen) for the move.

Today was daily transfer 12,301. With ~6.6 generations per day, they are now at ~82,007 generations.

100,000 generations is fast approaching! Are you ready, #Spartans?

@msumgi.bsky.social

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Chris Adami @chrisadami.bsky.social · 28d

www.nytimes.com/2025/09/07/s.... When David was President of Caltech he and I often ran on adjacent treadmills at the Gym, and we got to talking. He was very interested in the brain and consciousness, and we ended up friends. All around great guy.