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Reposted by Michael Baym

Dave Baltrus 🦦 @surtlab.bsky.social · 1d

Here’s published version of our manuscript using GWAS to investigate tailocin sensitivity in Pseudomonas syringae. TL:DR pretty clear LPS is tailocin receptor but also that P.syringae often completely swaps out its entire O antigen biosynth pathway w/ recombination

academic.oup.com/g3journal/ad...

Genomic correlates of tailocin sensitivity in Pseudomonas syringae

Abstract. Phage-derived bacteriocins, also referred to as tailocins, are structures encoded by bacterial genomes and deployed into the extracellular enviro

academic.oup.com

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Reposted by Michael Baym

Jeremy Berg @jeremymberg.bsky.social · 1d

6/14

In communicating with some of the scientists affected by grant terminations, it was striking (but not surprising) that many felt abandoned by their institutions and the scientific establishment at large. This was fueled, in part, by the contrast between this acquiescence and the rapid institutional responses, including lawsuits, after the administration had proposed a cap on the rate of reimbursement for so-called indirect costs of research. The scientific establishment had the capacity to push back vigorously when some of their values (financial viability) were threatened but could not seem to muster much energy when other principles were under assault.

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Michael Baym @baym.lol · 5d

So cool to see this work out!! I love it

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Reposted by Michael Baym

Vaughn Cooper @vscooper.micropopbio.org · 5d

DYK most P. aeruginosa carry filamentous phage(s) that don't need to kill the cell to reproduce?

We 👉🏻@nanamikubota.bsky.social show that these Pf phages can go ROGUE.

"Filamentous cheater phages drive bacterial and phage populations to lower fitness"

🔗 authors.elsevier.com/c/1lt5I3QW8S...

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Michael Baym @baym.lol · 6d

$5 says every single one of these is an LLM-powered bot at some farm trying to influence public opinion by arguing with and griefing certain points of view

worm @rfksbrainworm.bsky.social · 6d

really enjoying all the people trying to explain the bible to the pope today

Pope Leo XIV
Today, more than ever, we must return to the heart, the center of feeling and emotion, the locus of freedom. Though it includes reason, the heart transcends and transforms it. Only by returning to the heart can we undergo a true ecological conversion that transforms our personal

Austin
I reject this whole heartedly. What you fail to see Mr Pope, the Bible says

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Michael Baym @baym.lol · 6d

I cannot tell you how much I want to see someone draw this

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Michael Baym @baym.lol · 6d

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Michael Baym @baym.lol · 6d

Faculty meeting as memento mori

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Reposted by Michael Baym

Saloni @scientificdiscovery.dev · 7d

Most graphs of the fertility rate depict the 'period fertility rate', which is based on a single year's data and doesn't necessarily reflect how many children women actually have across their lifetimes.

I've used data from the Human Fertility Database to show the cumulative number instead:

Cohort fertility rates for the United States, by age 40, 45 and 50.

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Michael Baym @baym.lol · 7d

Second, that should affect total plasmid complement and not act differently on resistance carriage. @zaminiqbal.bsky.social’s recent paper on the same subject also finds plenty of old plasmids, so I would assume there isn’t a storage effect?

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Michael Baym @baym.lol · 7d

Thank you! I hadn’t considered that point before, but thinking about it, it seems unlikely to be a major source of bias for two reasons: first, to my understanding the NCTC were all freeze-dried exactly once before revival and sequencing, so there’s a time difference lyophilized but not cycles

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Reposted by Michael Baym

Max Kozlov @maxkozlov.bsky.social · 7d

Staff members at the NIH seem to have done the impossible: spend the agency's $48 billion budget.

“Everyone has been rallying together to clean up the mess, but it’s a mess that did not need to be made,” an NIH program officer told me.

www.nature.com/articles/d41...

NIH races to spend its 2025 grant money — but fewer projects win funding

Despite political obstacles, officials are on track to disburse all of the research funds allocated to US biomedical behemoth.

www.nature.com

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Reposted by Michael Baym

Harmit Singh Malik @harmitmalik.bsky.social · 8d

Trump Administration Opens New Front to Strip Harvard of Federal Funding

apple.news/ALbyXj8lfRAi...

Trump Administration Opens New Front to Strip Harvard of Federal Funding — The Wall Street Journal

The government is starting a process that could make the university ineligible for future funding

apple.news

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Michael Baym @baym.lol · 8d

It’s going great here 🫠🫠

Reposted by Michael Baym

Vaughn Cooper @vscooper.micropopbio.org · 8d

View from the lab now. Did I mention that we are recruiting faculty microbiologists?

www.linkedin.com/posts/vaughn...

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Reposted by Michael Baym

Molly Schumer @mollyschumer.bsky.social · 9d

What are people using for calling m6A from pacbio revio data? This is for analysis of fiberseq library. Any suggestions appreciated, we are newbies with m6A analysis!

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Reposted by Michael Baym

Wolfgang Huber @wkhuber.bsky.social · 9d

Do you like theoretical biology, mathematical&conceptual modelling and want to apply yourself to cutting-edge research at all levels of biology, from molecules to ecosystems?

Come to EMBL! Scope includes physics-based models, emergence, statistics, ML/AI
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

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Michael Baym @baym.lol · 9d

Did The Feed recently transition from a boring place to buy discount prepackaged sugar to a sketchy unregulated peptide dealer, or was it always and I only just noticed?

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Reposted by Michael Baym

Mark Copelovitch @mcopelov.bsky.social · 10d

We have allowed the lazy, grifting Silicon Valley charlatans into the front door, & in doing so, we have learned just how many of our own colleagues & administrators simply are not interested in the actual business of education. It's incredibly demoralizing.

bsky.app/profile/mcop...

Erin Lockwood @erinkaylockwood.bsky.social · 10d

Thanks so much for your reporting on this, Ben. I just got an email from my campus's IT office triumphantly advertising free student access to four different AI models -- at the same time as we have a hiring freeze, caps on grad enrollment, and a 7% budget cut -- and wanted to scream.

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Reposted by Michael Baym

Tressie McMillan Cottom @tressiemcphd.bsky.social · 10d

It is, far and away, the most challenging thing I’ve encountered since entering the academy. And that is saying a lot. I might be working on this but I keep putting it aside because I’m not medicated enough to describe how demoralizing it all is.

Mark Copelovitch @mcopelov.bsky.social · 10d

We have allowed the lazy, grifting Silicon Valley charlatans into the front door, & in doing so, we have learned just how many of our own colleagues & administrators simply are not interested in the actual business of education. It's incredibly demoralizing.

bsky.app/profile/mcop...

Erin Lockwood @erinkaylockwood.bsky.social · 10d

Thanks so much for your reporting on this, Ben. I just got an email from my campus's IT office triumphantly advertising free student access to four different AI models -- at the same time as we have a hiring freeze, caps on grad enrollment, and a 7% budget cut -- and wanted to scream.

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Reposted by Michael Baym

Drug Monkey @drugmonkey.bsky.social · 10d

Whether you think limiting student visas to 4 years is a good or bad thing, please comment. Be heard.

Dr. Kat Napaaqtuk❄️ @napaaqtuk.bsky.social · 11d

Comment period ends on Monday for a proposed rule change that would terminate student visas after 4 years. It also puts limits on exchange visitors and reps of foreign media, and shortens the length of time at the end of the visa from 60 days to 30 days.

www.federalregister.gov/documents/20...

Establishing a Fixed Time Period of Admission and an Extension of Stay Procedure for Nonimmigrant Academic Students, Exchange Visitors, and Representatives of Foreign Information Media

Unlike most nonimmigrant classifications, which are admitted for a fixed time period, aliens in the F (academic student), J (exchange visitor), and most I (representatives of foreign information media...

www.federalregister.gov

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Reposted by Michael Baym

Dr. Kat Napaaqtuk❄️ @napaaqtuk.bsky.social · 11d

Comment period ends on Monday for a proposed rule change that would terminate student visas after 4 years. It also puts limits on exchange visitors and reps of foreign media, and shortens the length of time at the end of the visa from 60 days to 30 days.

www.federalregister.gov/documents/20...

Establishing a Fixed Time Period of Admission and an Extension of Stay Procedure for Nonimmigrant Academic Students, Exchange Visitors, and Representatives of Foreign Information Media

Unlike most nonimmigrant classifications, which are admitted for a fixed time period, aliens in the F (academic student), J (exchange visitor), and most I (representatives of foreign information media...

www.federalregister.gov

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Reposted by Michael Baym

Type VI Sophia System @wheezenfeld.bsky.social · 11d

Really cool work on anthropomorphic driven change of plasmids :)!
www.science.org/doi/10.1126/...

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Michael Baym @baym.lol · 11d

I truly don’t think owners of off-leash dogs near newborns and their parents understand how much danger their pets are in

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Reposted by Michael Baym

👻madeline boOoOoOodent👻 @oldenoughtosay.com · 12d

thank you all for telling me it was actually half a teaspoon of chilli flakes; that is still not enough but also I can’t read idk.

And now!! The ultimate test!
It is time to summon my French husband

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