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Genetic and environmental control of parasexual reproduction in the pathogenic Candida species | Microbiology and Molecular Biology Reviews

Reposted by Clement Tsui PhD 🇭🇰 🇨🇦

Center for Advanced Microbiome Research & Innovation (CAMRI) @camri-igs.bsky.social · 4d

We're hiring a #postdoc with knowledge of the #microbiome, #microbiology, #bioinformatics, #computationalbiology to understand the role of the vaginal microbiome in women's health. #Baltimore #womenshealth

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Clement Tsui PhD 🇭🇰 🇨🇦 @clementsui.bsky.social · 4d

Genetic and environmental control of parasexual reproduction in the pathogenic #Candida species | Microbiology and Molecular Biology Reviews journals.asm.org/doi/abs/10.1...

SUMMARYCandida species are major yeast pathogens that cause both mucosal candidiasis and life-threatening invasive infections. Most Candida species, including Candida albicans, have long been thought ...

mGem: Submarine mycology—an analog to astromycology | mBio

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Clement Tsui PhD 🇭🇰 🇨🇦 @clementsui.bsky.social · 5d

sounds scary!
mGem: Submarine #mycology—an analog to astromycology | mBio journals.asm.org/doi/10.1128/...

Astromycology, the study of fungi in space environments, has emerged as a critical field for understanding both their risks and potential applications (1). Among the most pressing concerns is the prot...

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Clement Tsui PhD 🇭🇰 🇨🇦 @clementsui.bsky.social · 5d

Everyone losers 🥲

Dual transposon sequencing profiles the genetic interaction landscape in bacteria

Reposted by Clement Tsui PhD 🇭🇰 🇨🇦

Biological Journal of the Linnean Society @biojlinnsoc.bsky.social · 11d

Are you a PhD student ready to publish a paper? Submit your research to our journal today & enter one of our new journal prizes, celebrating PhD student work in #Botany or #Biology !🧪🌍👇
academic.oup.com/biolinnean/p...
@linneansociety.bsky.social

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Reposted by Clement Tsui PhD 🇭🇰 🇨🇦

Di Jiang @dijiang319.bsky.social · 12d

This week @science.org Dual #transposon sequencing profiles the #genetic interaction landscape in #bacteria | Science www.science.org/doi/10.1126/... 🦠🔬🧫🧬

Gene redundancy complicates systematic characterization of gene function as single-gene deletions may not produce discernible phenotypes. We report dual transposon sequencing (dual Tn-seq), a platform...

www.science.org

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Clement Tsui PhD 🇭🇰 🇨🇦 @clementsui.bsky.social · 13d

Acquired amphotericin B resistance attributed to a mutated ERG3 in Candidozyma auris | Antimicrobial Agents and Chemotherapy journals.asm.org/doi/full/10....

Acquired amphotericin B resistance attributed to a mutated ERG3 in Candidozyma auris | Antimicrobial Agents and Chemotherapy

In 2019, the Centers for Disease Control and Prevention (CDC) designated Candidozyma auris (previously known as Candida auris) as an urgent antimicrobial threat, making it the first fungal pathogen to...

Dynamic airborne mycobiome in the metropolitan city transit system is driven by seasonality and station type | Microbiology Spectrum

Clement Tsui PhD 🇭🇰 🇨🇦 @clementsui.bsky.social · 13d

Dynamic airborne mycobiome in the metropolitan city transit system is driven by seasonality and station type | Microbiology Spectrum journals.asm.org/doi/10.1128/...

Respiratory infections and allergic reactions caused by airborne fungi have received considerable public attention; however, fungal communities remain poorly investigated. This research performed the ...

Gut fungal profiles reveal phylosymbiosis and codiversification across humans and nonhuman primates

Clement Tsui PhD 🇭🇰 🇨🇦 @clementsui.bsky.social · 15d

Gut #fungal profiles reveal phylosymbiosis and codiversification across humans and nonhuman primates dx.plos.org/10.1371/jour...

Fungi in the gut microbiome (the "mycobiome") are a neglected component of the human holobiont. This study of gut fungal profiles across natural populations of humans and non-human primates reveals si...

dx.plos.org

Clement Tsui PhD 🇭🇰 🇨🇦 @clementsui.bsky.social · 15d

Complex Genomic Landscape of Inversion Polymorphism in Europe's Most Destructive Forest Pest url: academic.oup.com/gbe/article/...

academic.oup.com

Clement Tsui PhD 🇭🇰 🇨🇦 @clementsui.bsky.social · 17d

wow, what a mess! Blessings

Fungal resistance in rice is restored by interfamily transfer of an evolutionarily lost co-receptor

Reposted by Clement Tsui PhD 🇭🇰 🇨🇦

Cameron Thrash @jcamthrash.bsky.social · 19d

How sequencing technology shapes our understanding of river water microbiomes and resistomes: a comparative study journals.asm.org/doi/full/10.... #jcampubs

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Reposted by Clement Tsui PhD 🇭🇰 🇨🇦

Rike Stelkens @stelkens.bsky.social · 20d

We have a new paper out in Molecular Ecology, led by @devinbendixsen.bsky.social ! Reproductive isolation due to divergent ecological selection is accompanied by vast genomic instability in experimentally evolved yeast populations onlinelibrary.wiley.com/doi/10.1111/...

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Clement Tsui PhD 🇭🇰 🇨🇦 @clementsui.bsky.social · 19d

Fungal resistance in rice is restored by interfamily transfer of an evolutionarily lost co-receptor: Cell Host & Microbe www.cell.com/cell-host-mi...

Zhang et al. identify STOM, a previously unknown fungal MAMP, and its receptor-co-receptor pair, STOMR/STOMRh. The evolutionary loss of functional STOMRh in monocots restricts immune recognition, whil...

www.cell.com

How Klebsiella pneumoniae controls its virulence

Clement Tsui PhD 🇭🇰 🇨🇦 @clementsui.bsky.social · 19d

Checkout this article I found at PLOS: dx.plos.org/10.1371/jour...

The bacterial pathogen Klebsiella pneumoniae is a serious public health threat due to its propensity to develop antimicrobial resistance (AMR), the emergence of hypervirulent strains able to cause com...

dx.plos.org

Long-term monitoring of a North American cheese cave reveals mechanisms and consequences of fungal adaptation

Reposted by Clement Tsui PhD 🇭🇰 🇨🇦

Cameron Thrash @jcamthrash.bsky.social · 23d

Aquatic fungal diversity assessment through metagenomics is still limited to current databases aslopubs.onlinelibrary.wiley.com/doi/10.1002/... #jcampubs

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Reposted by Clement Tsui PhD 🇭🇰 🇨🇦

Ákos T Kovács @evolvedbiofilm.bsky.social · 24d

Long-term monitoring of a North American cheese cave reveals mechanisms and consequences of fungal adaptation

Penicillium solitum over 8 years in a cheese cave => green-to-white shift

@currentbiology.bsky.social from @benwolfe.bsky.social with @kellerlab.bsky.social

www.cell.com/current-biol...

Using a unique longitudinal sampling approach, Louw et al. demonstrate how a cheese-associated Penicillium population has adapted in an artisan cheese production facility in Vermont, USA. Adaptation i...

www.cell.com

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Reposted by Clement Tsui PhD 🇭🇰 🇨🇦

Methods in Ecology and Evolution @methodsinecoevol.bsky.social · 26d

📖Published📖

Pappalardo et al. developed taxon-specific confidence thresholds for eukaryotes at different taxonomic levels to optimize the accuracy of BLAST-based taxonomic assignments for metabarcoding 🧬 🌍 🧪 Read more here 👇

Taxon‐specific BLAST percent identity thresholds for identification of unknown sequences using metabarcoding

The identification of organisms in environmental samples using metabarcoding relies on factors such as taxonomic assignment methods, genetic markers, reference databases and confidence thresholds ...

buff.ly

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Clement Tsui PhD 🇭🇰 🇨🇦 @clementsui.bsky.social · 25d

www.biorxiv.org/content/10.1...

Genomic rearrangements at the MAT locus suggest reproductive shifts in Rhodotorula yeasts

Rhodotorula, a red yeast genus inhabiting diverse environmental and clinical niches, is a promising microbial source for carotenoid and lipid production. Despite the coexistence of sexual and asexual ...

www.biorxiv.org

The landscape of microbial associations in human cancer

Clement Tsui PhD 🇭🇰 🇨🇦 @clementsui.bsky.social · 25d

The landscape of microbial associations in human cancer | Science Translational Medicine www.science.org/doi/10.1126/...

Differences between cancer types, infectious disease, and potential prognostic markers are uncovered by studying microbes within cancer DNA.

www.science.org

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Clement Tsui PhD 🇭🇰 🇨🇦 @clementsui.bsky.social · 26d

Checkout this article I found at PLOS: dx.plos.org/10.1371/jour...

The dimorphic fungus Talaromyces marneffei: An opportunistic killer in Southeast Asia

dx.plos.org

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Reposted by Clement Tsui PhD 🇭🇰 🇨🇦

Zamin Iqbal @zaminiqbal.bsky.social · 28d

Sometimes you meet absolutely incredible bioinfo-magicians.
It was a huge privilege when @shenwei356.bsky.social
joined our group for a year on an @embl.org sabbatical.
While here, he developed a new way of aligning to
millions of bacteria, called LexicMap 1/n
www.nature.com/articles/s41...

Efficient sequence alignment against millions of prokaryotic genomes with LexicMap - Nature Biotechnology

LexicMap uses a fixed set of probes to efficiently query gene sequences for fast and low-memory alignment.

www.nature.com

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Clement Tsui PhD 🇭🇰 🇨🇦 @clementsui.bsky.social · 29d

Conflicts drive #AMR! www.sciencedirect.com/science/arti...

Comparison of carbapenemase-producing Enterobacterales colonizing war-affected children from the Gaza Strip and hospitalized children from a national reference center in Qatar: An observational cohort...

To compare the rates and molecular characteristics of carbapenemase-producing Enterobacterales (CPE) from rectal screening swabs in war-affected Pales…

www.sciencedirect.com

An update on clinically relevant, rare, and emerging Candida and Saccharomycotina yeasts that have been recently reclassified from Candida | Clinical Microbiology Reviews

Clement Tsui PhD 🇭🇰 🇨🇦 @clementsui.bsky.social · Sep 8

An update on clinically relevant, rare, and emerging Candida and Saccharomycotina yeasts that have been recently reclassified from Candida | Clinical Microbiology Reviews journals.asm.org/doi/abs/10.1...

SUMMARYMany yeast species causing life-threatening invasive infections that were formerly classified in the genus Candida have been reclassified due to their evolutionary and phylogenetic relationships elucidated by DNA sequencing methods that are ...